Short-chain fatty acids from periodontal pathogens suppress histone deacetylases, EZH2, and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication

Journal of Virology

Volumn 88, Issue 8, 2014, Pages 4466-4479

  Yu, Xiaolan ^a,c   Shahir, Abdel Malek ^a   Sha, Jingfeng ^a   Feng, Zhimin ^a   Eapen, Betty ^a   Nithianantham, Stanley ^a   Das, Biswajit ^b   Karn, Jonathan ^b   Weinberg, Aaron ^a   Bissada, Nabil F ^a   Ye, Fengchun ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HUBEI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; HISTONE DEACETYLASE; HISTONE LYSINE METHYLTRANSFERASE; SILENT INFORMATION REGULATOR PROTEIN; SILENT INFORMATION REGULATOR PROTEIN 1; SUPPRESSOR OF VARIEGATION 3 9 HOMOLOG1; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; ENZYME REPRESSION; FATTY ACID BLOOD LEVEL; FEMALE; FUSOBACTERIUM NUCLEATUM; GENE EXPRESSION; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; KAPOSI SARCOMA; MALE; MOUTH CAVITY; NONHUMAN; PATHOGENESIS; PERIODONTAL DISEASE; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; RISK FACTOR; SALIVA ANALYSIS; VIRUS REPLICATION;

ADULT; AGED; COINFECTION; DOWN-REGULATION; FATTY ACIDS, VOLATILE; FEMALE; FUSOBACTERIUM NUCLEATUM; HERPESVIRUS 8, HUMAN; HUMANS; MALE; METHYLTRANSFERASES; MIDDLE AGED; PERIODONTAL DISEASES; POLYCOMB REPRESSIVE COMPLEX 2; PORPHYROMONAS GINGIVALIS; REPRESSOR PROTEINS; SARCOMA, KAPOSI; VIRUS REPLICATION;

EID: 84896993870     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03326-13     Document Type: Article

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