-
1
-
-
85020530779
-
Nephroprotection by hypoglycemic agents: do we have supporting data?
-
Górriz JL, Nieto J, Navarro-González JF, Molina P, Martínez-Castelao A, Pallardó LM. Nephroprotection by hypoglycemic agents: do we have supporting data? J Clin Med. 2015;4:1866-1889.
-
(2015)
J Clin Med
, vol.4
, pp. 1866-1889
-
-
Górriz, J.L.1
Nieto, J.2
Navarro-González, J.F.3
Molina, P.4
Martínez-Castelao, A.5
Pallardó, L.M.6
-
2
-
-
33645472464
-
Renal protection in diabetes: role of glycemic control
-
Fioretto P, Bruseghin M, Berto I, Gallina P, Manzato E, Mussap M. Renal protection in diabetes: role of glycemic control. J Am Soc Nephrol. 2006;17:S86-S89.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. S86-S89
-
-
Fioretto, P.1
Bruseghin, M.2
Berto, I.3
Gallina, P.4
Manzato, E.5
Mussap, M.6
-
3
-
-
79551469139
-
Drug-induced chan-ges in risk/biomarkers and their relationship with renal and cardiovas-cular long-term outcome in patients with diabetes
-
Miao Y, Smink PA, de Zeeuw D, Lambers Heerspink HJ. Drug-induced chan-ges in risk/biomarkers and their relationship with renal and cardiovas-cular long-term outcome in patients with diabetes. Clin Chem. 2011;57:186-195.
-
(2011)
Clin Chem
, vol.57
, pp. 186-195
-
-
Miao, Y.1
Smink, P.A.2
de Zeeuw, D.3
Lambers Heerspink, H.J.4
-
4
-
-
45149133036
-
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
-
ADVANCE Collaborative Group, Patel A, MacMahon S, et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med. 2008;358:2560-2572.
-
(2008)
N Engl J Med
, vol.358
, pp. 2560-2572
-
-
Patel, A.1
MacMahon, S.2
-
5
-
-
77955585592
-
Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial
-
Ismail-Beigi F, Craven T, Banerji MA, et al. Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet. 2010;376:419-430.
-
(2010)
Lancet
, vol.376
, pp. 419-430
-
-
Ismail-Beigi, F.1
Craven, T.2
Banerji, M.A.3
-
6
-
-
58149389215
-
Glucose control and vascular complications in veterans with type 2 diabetes
-
Duckworth W, Abraira C, Moritz T, et al. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med. 2009;36:129-139.
-
(2009)
N Engl J Med
, vol.36
, pp. 129-139
-
-
Duckworth, W.1
Abraira, C.2
Moritz, T.3
-
7
-
-
84979895487
-
Empagliflozin and progression of kidney disease in type 2 diabetes
-
Wanner C, Inzucchi SE, Lachin JM, et al. Empagliflozin and progression of kidney disease in type 2 diabetes. N Engl J Med. 2016;375:323-334.
-
(2016)
N Engl J Med
, vol.375
, pp. 323-334
-
-
Wanner, C.1
Inzucchi, S.E.2
Lachin, J.M.3
-
8
-
-
84891588645
-
Comparative effectiveness of renin-angiotensin system blockers and other antihypertensive drugs in patients with diabetes: systematic review and bayesian network meta-analysis
-
HY W, Huang JW, Lin HJ, et al. Comparative effectiveness of renin-angiotensin system blockers and other antihypertensive drugs in patients with diabetes: systematic review and bayesian network meta-analysis. BMJ. 2013;347:f6008. https://doi.org/10.1136/bmj.f6008.
-
(2013)
BMJ
, vol.347
, pp. 6008
-
-
Hy, W.1
Huang, J.W.2
Lin, H.J.3
-
9
-
-
84992144623
-
Efficacy of statins in patients with diabetic nephropathy: a meta-analysis of randomized controlled trials
-
Shen X, Zhang Z, Zhang X, et al. Efficacy of statins in patients with diabetic nephropathy: a meta-analysis of randomized controlled trials. Lipids Health Dis. 2016;15:179.
-
(2016)
Lipids Health Dis
, vol.15
, pp. 179
-
-
Shen, X.1
Zhang, Z.2
Zhang, X.3
-
10
-
-
84876497088
-
Recent advances in understanding the biochemical and molecular mechanism of diabetic nephropathy
-
Sun YM, Su Y, Li J, Wang LF. Recent advances in understanding the biochemical and molecular mechanism of diabetic nephropathy. Biochem Biophys Res Commun. 2013;433:359-361.
-
(2013)
Biochem Biophys Res Commun
, vol.433
, pp. 359-361
-
-
Sun, Y.M.1
Su, Y.2
Li, J.3
Wang, L.F.4
-
12
-
-
84940702428
-
Physiological functions and regulation of the Na+/H+ exchanger [NHE1] in renal tubule epithelial cells
-
Vallés PG, Bocanegra V, Gil Lorenzo A, Costantino VV. Physiological functions and regulation of the Na+/H+ exchanger [NHE1] in renal tubule epithelial cells. Kidney Blood Press Res. 2015;40:452-466.
-
(2015)
Kidney Blood Press Res
, vol.40
, pp. 452-466
-
-
Vallés, P.G.1
Bocanegra, V.2
Gil Lorenzo, A.3
Costantino, V.V.4
-
15
-
-
84867885513
-
Role of the Na(+)/H(+) exchanger on the development of diabetes mellitus and its chronic complications
-
Sun YM, Su Y, Li J, Tian Y, Wang LF. Role of the Na(+)/H(+) exchanger on the development of diabetes mellitus and its chronic complications. Biochem Biophys Res Commun. 2012;427:229-231.
-
(2012)
Biochem Biophys Res Commun
, vol.427
, pp. 229-231
-
-
Sun, Y.M.1
Su, Y.2
Li, J.3
Tian, Y.4
Wang, L.F.5
-
16
-
-
30644465312
-
Acute and chronic regulation of the renal Na/H+ exchanger NHE3 in rats with STZ-induced diabetes mellitus
-
Klisic J, Nief V, Reyes L, Ambuhl PM. Acute and chronic regulation of the renal Na/H+ exchanger NHE3 in rats with STZ-induced diabetes mellitus. Nephron Physiol. 2006;102:27-35.
-
(2006)
Nephron Physiol
, vol.102
, pp. 27-35
-
-
Klisic, J.1
Nief, V.2
Reyes, L.3
Ambuhl, P.M.4
-
17
-
-
0033963490
-
High glucose induces the activity and expression of Na(+)/H(+) exchange in glomerular mesangial cells
-
Ganz MB, Hawkins K, Reilly RF. High glucose induces the activity and expression of Na(+)/H(+) exchange in glomerular mesangial cells. Am J Physiol Renal Physiol. 2000;278:F91-F96.
-
(2000)
Am J Physiol Renal Physiol
, vol.278
, pp. F91-F96
-
-
Ganz, M.B.1
Hawkins, K.2
Reilly, R.F.3
-
19
-
-
0029043165
-
Activity and expression of the Na+/H+ exchanger in human endothelial cells cultured in high glucose
-
Zerbini G, Roth T, Podestá F, et al. Activity and expression of the Na+/H+ exchanger in human endothelial cells cultured in high glucose. Diabetologia. 1995;38:785-791.
-
(1995)
Diabetologia
, vol.38
, pp. 785-791
-
-
Zerbini, G.1
Roth, T.2
Podestá, F.3
-
20
-
-
84949996614
-
Inhibition of Na(+)/H(+) exchanger 1 attenuates renal dysfunction induced by advanced glycation end products in rats
-
1802036
-
Li P, Chen GR, Wang F, et al. Inhibition of Na(+)/H(+) exchanger 1 attenuates renal dysfunction induced by advanced glycation end products in rats. J Diabetes Res. 2016;2016:1802036. https://doi.org/10.1155/2016/1802036.
-
(2016)
J Diabetes Res
, vol.2016
-
-
Li, P.1
Chen, G.R.2
Wang, F.3
-
22
-
-
84877948801
-
Acid loading stimulates rat glomerular mesangial cells proliferation through Na(+)-H (+) exchanger isoform 1 (NHE1)-depend-ent pathway
-
Li K, Su W, Li M, et al. Acid loading stimulates rat glomerular mesangial cells proliferation through Na(+)-H (+) exchanger isoform 1 (NHE1)-depend-ent pathway. Naunyn Schmiedebergs Arch Pharmacol. 2013;386:563-569.
-
(2013)
Naunyn Schmiedebergs Arch Pharmacol
, vol.386
, pp. 563-569
-
-
Li, K.1
Su, W.2
Li, M.3
-
23
-
-
0036760072
-
Regulation of glomerular filtration in essential hypertension: role of abnormal Na+ transport and atrial natriuretic peptide
-
Semplicini A, Ceolotto G, Sartori M, et al. Regulation of glomerular filtration in essential hypertension: role of abnormal Na+ transport and atrial natriuretic peptide. J Nephrol. 2002;15:489-496.
-
(2002)
J Nephrol
, vol.15
, pp. 489-496
-
-
Semplicini, A.1
Ceolotto, G.2
Sartori, M.3
-
24
-
-
0141702083
-
Effects of pathophysiological concentrations of albumin on NHE3 activity and cell proliferation in primary cultures of human proximal tubule cells
-
Lee EM, Pollock CA, Drumm K, Barden JA, Poronnik P. Effects of pathophysiological concentrations of albumin on NHE3 activity and cell proliferation in primary cultures of human proximal tubule cells. Am J Physiol Renal Physiol. 2003;285:F748-F757.
-
(2003)
Am J Physiol Renal Physiol
, vol.285
, pp. F748-F757
-
-
Lee, E.M.1
Pollock, C.A.2
Drumm, K.3
Barden, J.A.4
Poronnik, P.5
-
25
-
-
85031915334
-
Activation and inhibition of sodium-hydrogen exchange is a mechanism that links the pathophysiology and treatment of diabetes with that of heart failure
-
Packer M. Activation and inhibition of sodium-hydrogen exchange is a mechanism that links the pathophysiology and treatment of diabetes with that of heart failure. Circulation. 2017;136:1548-1559.
-
(2017)
Circulation
, vol.136
, pp. 1548-1559
-
-
Packer, M.1
-
26
-
-
34447629085
-
Regulatory binding partners and complexes of NHE3
-
Donowitz M, Li X. Regulatory binding partners and complexes of NHE3. Physiol Rev. 2007;87:825-872.
-
(2007)
Physiol Rev
, vol.87
, pp. 825-872
-
-
Donowitz, M.1
Li, X.2
-
28
-
-
35348845831
-
Insulin's impact on renal sodium transport and blood pressure in health, obesity, and diabetes
-
Tiwari S, Riazi S, Ecelbarger CA. Insulin's impact on renal sodium transport and blood pressure in health, obesity, and diabetes. Am J Physiol Renal Physiol. 2007;293:F974-F984.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. F974-F984
-
-
Tiwari, S.1
Riazi, S.2
Ecelbarger, C.A.3
-
29
-
-
84876548389
-
Thiazolidinedione-induced fluid retention: recent insights into the molecular mechanisms
-
628628
-
Bełtowski J, Rachańczyk J, Włodarczyk M. Thiazolidinedione-induced fluid retention: recent insights into the molecular mechanisms. PPAR Res. 2013;2013:628628. https://doi.org/10.1155/2013/628628.
-
(2013)
PPAR Res
, vol.2013
-
-
Bełtowski, J.1
Rachańczyk, J.2
Włodarczyk, M.3
-
30
-
-
7044253431
-
A meta-analysis comparing the effect of thiazolidinediones on cardiovascular risk factors
-
Chiquette E, Ramirez G, Defronzo R. A meta-analysis comparing the effect of thiazolidinediones on cardiovascular risk factors. Arch Intern Med. 2004;164:2097-2104.
-
(2004)
Arch Intern Med
, vol.164
, pp. 2097-2104
-
-
Chiquette, E.1
Ramirez, G.2
Defronzo, R.3
-
31
-
-
84864270406
-
Basal insulin and cardiovascular and other outcomes in dysglycemia
-
ORIGIN Trial Investigators, Gerstein HC, Bosch J, et al. Basal insulin and cardiovascular and other outcomes in dysglycemia. N Engl J Med. 2012;367:319-328.
-
(2012)
N Engl J Med
, vol.367
, pp. 319-328
-
-
Gerstein, H.C.1
Bosch, J.2
-
32
-
-
33846883310
-
Characterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin
-
Fuster DG, Bobulescu IA, Zhang J, Wade J, Moe OW. Characterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin. Am J Physiol Renal Physiol. 2007;292:F577-F585.
-
(2007)
Am J Physiol Renal Physiol
, vol.292
, pp. F577-F585
-
-
Fuster, D.G.1
Bobulescu, I.A.2
Zhang, J.3
Wade, J.4
Moe, O.W.5
-
33
-
-
0025858999
-
Insulin increases Na(+)-H+ exchange activity in proximal tubules from normotensive and hypertensive rats
-
Gesek FA, Schoolwerth AC. Insulin increases Na(+)-H+ exchange activity in proximal tubules from normotensive and hypertensive rats. Am J Physiol. 1991;260:F695-F703.
-
(1991)
Am J Physiol
, vol.260
, pp. F695-F703
-
-
Gesek, F.A.1
Schoolwerth, A.C.2
-
34
-
-
65349084594
-
The role of Sgk-1 in the upregulation of transport proteins by PPAR-{gamma} agonists in human proximal tubule cells
-
Saad S, Agapiou DJ, Chen XM, Stevens V, Pollock CA. The role of Sgk-1 in the upregulation of transport proteins by PPAR-{gamma} agonists in human proximal tubule cells. Nephrol Dial Transplant. 2009;24:1130-1141.
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 1130-1141
-
-
Saad, S.1
Agapiou, D.J.2
Chen, X.M.3
Stevens, V.4
Pollock, C.A.5
-
35
-
-
79955624781
-
Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARγ-dependent nongenomic signaling
-
Endo Y, Suzuki M, Yamada H, et al. Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARγ-dependent nongenomic signaling. Cell Metab. 2011;13:550-561.
-
(2011)
Cell Metab
, vol.13
, pp. 550-561
-
-
Endo, Y.1
Suzuki, M.2
Yamada, H.3
-
36
-
-
82255181476
-
PPARγ2 P12A polymorphism and albuminuria in patients with type 2 diabetes: a meta-analysis of case-control studies
-
De Cosmo S, Prudente S, Lamacchia O, et al. PPARγ2 P12A polymorphism and albuminuria in patients with type 2 diabetes: a meta-analysis of case-control studies. Nephrol Dial Transplant. 2011;26:4011-4016.
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 4011-4016
-
-
De Cosmo, S.1
Prudente, S.2
Lamacchia, O.3
-
37
-
-
24944536256
-
A pilot randomized controlled trial of renal protection with pioglitazone in diabetic nephropathy
-
Agarwal R, Saha C, Battiwala M, et al. A pilot randomized controlled trial of renal protection with pioglitazone in diabetic nephropathy. Kidney Int. 2005;68:285-292.
-
(2005)
Kidney Int
, vol.68
, pp. 285-292
-
-
Agarwal, R.1
Saha, C.2
Battiwala, M.3
-
38
-
-
9244227632
-
Improvement of insulin sensitivity by metformin treatment does not lower blood pressure of nonobese insulin-resistant hypertensive patients with normal glucose tolerance
-
Dorella M, Giusto M, Da Tos V, et al. Improvement of insulin sensitivity by metformin treatment does not lower blood pressure of nonobese insulin-resistant hypertensive patients with normal glucose tolerance. J Clin Endocrinol Metab. 1996;81:1568-1574.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1568-1574
-
-
Dorella, M.1
Giusto, M.2
Da Tos, V.3
-
39
-
-
0034874812
-
Sulfonylurea receptors inhibit the epithelial sodium channel (ENaC) by reducing surface expression
-
Konstas AA, Bielfeld-Ackermann A, Korbmacher C. Sulfonylurea receptors inhibit the epithelial sodium channel (ENaC) by reducing surface expression. Pflugers Arch. 2001;442:752-761.
-
(2001)
Pflugers Arch
, vol.442
, pp. 752-761
-
-
Konstas, A.A.1
Bielfeld-Ackermann, A.2
Korbmacher, C.3
-
40
-
-
0141519823
-
Stimulation of epithelial sodium channel activity by the sulfonylurea glibenclamide
-
Chrabi A, Horisberger JD. Stimulation of epithelial sodium channel activity by the sulfonylurea glibenclamide. J Pharmacol Exp Ther. 1999;290:341-347.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 341-347
-
-
Chrabi, A.1
Horisberger, J.D.2
-
41
-
-
70449360911
-
Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: new results from the ADVANCE trial
-
Zoungas S, de Galan BE, Ninomiya T, et al. Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: new results from the ADVANCE trial. Diabetes Care. 2009;32:2068-2074.
-
(2009)
Diabetes Care
, vol.32
, pp. 2068-2074
-
-
Zoungas, S.1
de Galan, B.E.2
Ninomiya, T.3
-
42
-
-
79957824748
-
Renal function in type 2 diabetes with rosiglitazone, metformin, and glyburide monotherapy
-
Lachin JM, Viberti G, Zinman B, et al. Renal function in type 2 diabetes with rosiglitazone, metformin, and glyburide monotherapy. Clin J Am Soc Nephrol. 2011;6:1032-1040.
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, pp. 1032-1040
-
-
Lachin, J.M.1
Viberti, G.2
Zinman, B.3
-
43
-
-
84895072279
-
The gut-renal axis: do incretin-based agents confer renoprotection in diabetes?
-
Muskiet MH, Smits MM, Morsink LM, Diamant M. The gut-renal axis: do incretin-based agents confer renoprotection in diabetes? Nat Rev Nephrol. 2014;10:88-103.
-
(2014)
Nat Rev Nephrol
, vol.10
, pp. 88-103
-
-
Muskiet, M.H.1
Smits, M.M.2
Morsink, L.M.3
Diamant, M.4
-
44
-
-
84962332896
-
Incretin-based therapy for diabetes: what a cardiologist needs to know
-
Waldrop G, Zhong J, Peters M, Rajagopalan S. Incretin-based therapy for diabetes: what a cardiologist needs to know. J Am Coll Cardiol. 2016;67:1488-1496.
-
(2016)
J Am Coll Cardiol
, vol.67
, pp. 1488-1496
-
-
Waldrop, G.1
Zhong, J.2
Peters, M.3
Rajagopalan, S.4
-
45
-
-
85001850036
-
Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide: a randomized controlled trial in patients with type 2 diabetes
-
Nauck MA, Kahle M, Baranov O, Deacon CF, Holst JJ. Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide: a randomized controlled trial in patients with type 2 diabetes. Diabetes Obes Metab. 2017;19:200-207.
-
(2017)
Diabetes Obes Metab
, vol.19
, pp. 200-207
-
-
Nauck, M.A.1
Kahle, M.2
Baranov, O.3
Deacon, C.F.4
Holst, J.J.5
-
46
-
-
84930625640
-
DPP4 in cardiometabolic disease: recent insights from the laboratory and clinical trials of DPP4 inhibition
-
Zhong J, Maiseyeu A, Davis SN, Rajagopalan S. DPP4 in cardiometabolic disease: recent insights from the laboratory and clinical trials of DPP4 inhibition. Circ Res. 2015;116:1491-1504.
-
(2015)
Circ Res
, vol.116
, pp. 1491-1504
-
-
Zhong, J.1
Maiseyeu, A.2
Davis, S.N.3
Rajagopalan, S.4
-
47
-
-
2942668372
-
Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men
-
Gutzwiller JP, Tschopp S, Bock A, et al. Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men. J Clin Endocrinol Metab. 2004;89:3055-3061.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 3055-3061
-
-
Gutzwiller, J.P.1
Tschopp, S.2
Bock, A.3
-
48
-
-
84922572669
-
Time course and mechanisms of the anti-hypertensive and renal effects of liraglutide treatment
-
von Scholten BJ, Lajer M, Goetze JP, Persson F, Rossing P. Time course and mechanisms of the anti-hypertensive and renal effects of liraglutide treatment. Diabet Med. 2015;32:343-352.
-
(2015)
Diabet Med
, vol.32
, pp. 343-352
-
-
von Scholten, B.J.1
Lajer, M.2
Goetze, J.P.3
Persson, F.4
Rossing, P.5
-
49
-
-
38849093208
-
Dipeptidyl peptidase IV inhibition downregulates Na+ - H+ exchanger NHE3 in rat renal proximal tubule
-
Girardi AC, Fukuda LE, Rossoni LV, Malnic G, Rebouças NA. Dipeptidyl peptidase IV inhibition downregulates Na+ - H+ exchanger NHE3 in rat renal proximal tubule. Am J Physiol Renal Physiol. 2008;294:F414-F422.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, pp. F414-F422
-
-
Girardi, A.C.1
Fukuda, L.E.2
Rossoni, L.V.3
Malnic, G.4
Rebouças, N.A.5
-
50
-
-
84957427098
-
Effects of dipeptidyl peptidase-4 inhibitors on blood pressure in patients with type 2 diabetes: a systematic review and meta-analysis
-
Zhang X, Zhao Q. Effects of dipeptidyl peptidase-4 inhibitors on blood pressure in patients with type 2 diabetes: a systematic review and meta-analysis. J Hypertens. 2016;34:167-175.
-
(2016)
J Hypertens
, vol.34
, pp. 167-175
-
-
Zhang, X.1
Zhao, Q.2
-
51
-
-
79953826349
-
Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes
-
Kodera R, Shikata K, Kataoka HU, et al. Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes. Diabetologia. 2011;54:965-978.
-
(2011)
Diabetologia
, vol.54
, pp. 965-978
-
-
Kodera, R.1
Shikata, K.2
Kataoka, H.U.3
-
52
-
-
34047205064
-
Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice
-
Park CW, Kim HW, Ko SH, et al. Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice. J Am Soc Nephrol. 2007;18:1227-1238.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1227-1238
-
-
Park, C.W.1
Kim, H.W.2
Ko, S.H.3
-
53
-
-
84869238002
-
DPP-4 inhibition on top of angiotensin receptor blockade offers a new therapeutic approach for diabetic nephropathy
-
Alter ML, Ott IM, von Websky K, et al. DPP-4 inhibition on top of angiotensin receptor blockade offers a new therapeutic approach for diabetic nephropathy. Kidney Blood Press Res. 2012;36:119-130.
-
(2012)
Kidney Blood Press Res
, vol.36
, pp. 119-130
-
-
Alter, M.L.1
Ott, I.M.2
von Websky, K.3
-
54
-
-
84862944057
-
Dipeptidyl peptidase IV inhibitor attenuates kidney injury in streptozotocin-induced diabetic rats
-
Liu WJ, Xie SH, Liu YN, et al. Dipeptidyl peptidase IV inhibitor attenuates kidney injury in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther. 2012;340:248-255.
-
(2012)
J Pharmacol Exp Ther
, vol.340
, pp. 248-255
-
-
Liu, W.J.1
Xie, S.H.2
Liu, Y.N.3
-
55
-
-
85026922718
-
Microvascular effects of glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized controlled trials
-
Dicembrini I, Nreu B, Scatena A, et al. Microvascular effects of glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized controlled trials. Acta Diabetol. 2017;54(10):933-941. https://doi.org/10.1007/s00592-017-1031-9.
-
(2017)
Acta Diabetol
, vol.54
, Issue.10
, pp. 933-941
-
-
Dicembrini, I.1
Nreu, B.2
Scatena, A.3
-
56
-
-
85008230357
-
Effect of saxagliptin on renal outcomes in the SAVOR-TIMI 53 trial
-
Mosenzon O, Leibowitz G, Bhatt DL, et al. Effect of saxagliptin on renal outcomes in the SAVOR-TIMI 53 trial. Diabetes Care. 2017;40:69-76.
-
(2017)
Diabetes Care
, vol.40
, pp. 69-76
-
-
Mosenzon, O.1
Leibowitz, G.2
Bhatt, D.L.3
-
57
-
-
85026454641
-
Linagliptin and its effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: the randomized MARLINA-T2D trial
-
Groop PH, Cooper ME, Perkovic V, et al. Linagliptin and its effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: the randomized MARLINA-T2D trial. Diabetes Obes Metab. 2017;19:1610-1619. https://doi.org/10.1111/dom.13041.
-
(2017)
Diabetes Obes Metab
, vol.19
, pp. 1610-1619
-
-
Groop, P.H.1
Cooper, M.E.2
Perkovic, V.3
-
58
-
-
84978839381
-
Liraglutide and cardiovascular outcomes in type 2 diabetes
-
Marso SP, Daniels GH, Brown-Frandsen K, et al. Liraglutide and cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2016;375:311-322.
-
(2016)
N Engl J Med
, vol.375
, pp. 311-322
-
-
Marso, S.P.1
Daniels, G.H.2
Brown-Frandsen, K.3
-
60
-
-
84883765959
-
Saxagliptin and cardiovasc-ular outcomes in patients with type 2 diabetes mellitus
-
Scirica BM, Bhatt DL, Braunwald E, et al. Saxagliptin and cardiovasc-ular outcomes in patients with type 2 diabetes mellitus. N Engl J Med. 2013;369:1317-1326.
-
(2013)
N Engl J Med
, vol.369
, pp. 1317-1326
-
-
Scirica, B.M.1
Bhatt, D.L.2
Braunwald, E.3
-
61
-
-
84937053742
-
Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes
-
Green JB, Bethel MA, Armstrong PW, et al. Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2015;373:232-242.
-
(2015)
N Engl J Med
, vol.373
, pp. 232-242
-
-
Green, J.B.1
Bethel, M.A.2
Armstrong, P.W.3
-
63
-
-
85027575424
-
Dipeptidyl peptidase-4 inhibitors and the risk of heart failure: a systematic review and meta-analysis
-
Verma S, Goldenberg RM, Bhatt DL, et al. Dipeptidyl peptidase-4 inhibitors and the risk of heart failure: a systematic review and meta-analysis. CMAJ Open. 2017;5:E152-E177.
-
(2017)
CMAJ Open
, vol.5
, pp. E152-E177
-
-
Verma, S.1
Goldenberg, R.M.2
Bhatt, D.L.3
-
64
-
-
84901926135
-
Dipeptidyl peptidase-4 inhibitors and heart failure: a meta-analysis of randomized clinical trials
-
Monami M, Dicembrini I, Mannucci E. Dipeptidyl peptidase-4 inhibitors and heart failure: a meta-analysis of randomized clinical trials. Nutr Metab Cardiovasc Dis. 2014;24:689-697.
-
(2014)
Nutr Metab Cardiovasc Dis
, vol.24
, pp. 689-697
-
-
Monami, M.1
Dicembrini, I.2
Mannucci, E.3
-
65
-
-
84917723836
-
Heart failure, saxagliptin, and diabetes mellitus: observations from the SAVOR-TIMI 53 randomized trial
-
Scirica BM, Braunwald E, Raz I, et al. Heart failure, saxagliptin, and diabetes mellitus: observations from the SAVOR-TIMI 53 randomized trial. Circulation. 2014;130:1579-1588.
-
(2014)
Circulation
, vol.130
, pp. 1579-1588
-
-
Scirica, B.M.1
Braunwald, E.2
Raz, I.3
-
66
-
-
84955301664
-
The physiological role of glucagon-like peptide-1 in the regulation of renal function
-
Farah LX, Valentini V, Pessoa TD, Malnic G, McDonough AA, Girardi AC. The physiological role of glucagon-like peptide-1 in the regulation of renal function. Am J Physiol Renal Physiol. 2016;310:F123-F127.
-
(2016)
Am J Physiol Renal Physiol
, vol.310
, pp. F123-F127
-
-
Farah, L.X.1
Valentini, V.2
Pessoa, T.D.3
Malnic, G.4
McDonough, A.A.5
Girardi, A.C.6
-
67
-
-
57049179612
-
Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation status
-
Yang LE, Sandberg MB, Can AD, Pihakaski-Maunsbach K, McDonough AA. Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation status. Am J Physiol Renal Physiol. 2008;295:F1003-F1016.
-
(2008)
Am J Physiol Renal Physiol
, vol.295
, pp. F1003-F1016
-
-
Yang, L.E.1
Sandberg, M.B.2
Can, A.D.3
Pihakaski-Maunsbach, K.4
McDonough, A.A.5
-
68
-
-
71449111050
-
Regulation of Na+/H+ exchanger NHE3 by glucagon-like peptide 1 receptor agonist exendin-4 in renal proximal tubule cells
-
Carraro-Lacroix LR, Malnic G, Girardi AC. Regulation of Na+/H+ exchanger NHE3 by glucagon-like peptide 1 receptor agonist exendin-4 in renal proximal tubule cells. Am J Physiol Renal Physiol. 2009;297:F1647-F1655.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F1647-F1655
-
-
Carraro-Lacroix, L.R.1
Malnic, G.2
Girardi, A.C.3
-
69
-
-
0035824614
-
Association of Na(+)-H(+) exchanger isoform NHE3 and dipeptidyl peptidase IV in the renal proximal tubule
-
Girardi AC, Degray BC, Nagy T, Biemesderfer D, Aronson PS. Association of Na(+)-H(+) exchanger isoform NHE3 and dipeptidyl peptidase IV in the renal proximal tubule. J Biol Chem. 2001;276:46671-46677.
-
(2001)
J Biol Chem
, vol.276
, pp. 46671-46677
-
-
Girardi, A.C.1
Degray, B.C.2
Nagy, T.3
Biemesderfer, D.4
Aronson, P.S.5
-
70
-
-
79961180020
-
Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1
-
Crajoinas RO, Oricchio FT, Pessoa TD, et al. Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1. Am J Physiol Renal Physiol. 2011;301:F355-F363.
-
(2011)
Am J Physiol Renal Physiol
, vol.301
, pp. F355-F363
-
-
Crajoinas, R.O.1
Oricchio, F.T.2
Pessoa, T.D.3
-
71
-
-
6044261454
-
Role of dipeptidyl peptidase IV in regulating activity of Na+/H+ exchanger isoform NHE3 in proximal tubule cells
-
Girardi AC, Knauf F, Demuth HU, Aronson PS. Role of dipeptidyl peptidase IV in regulating activity of Na+/H+ exchanger isoform NHE3 in proximal tubule cells. Am J Physiol Cell Physiol. 2004;287:C1238-C1245.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
, pp. C1238-C1245
-
-
Girardi, A.C.1
Knauf, F.2
Demuth, H.U.3
Aronson, P.S.4
-
72
-
-
84867136387
-
Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice
-
Rieg T, Gerasimova M, Murray F, et al. Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice. Am J Physiol Renal Physiol. 2012;303:F963-F971.
-
(2012)
Am J Physiol Renal Physiol
, vol.303
, pp. F963-F971
-
-
Rieg, T.1
Gerasimova, M.2
Murray, F.3
-
73
-
-
84908295120
-
Intestinal regulation of urinary sodium excretion and the pathophysiology of diabetic kidney disease: a focus on glucagon-like peptide 1 and dipeptidyl peptidase 4
-
Vallon V, Docherty NG. Intestinal regulation of urinary sodium excretion and the pathophysiology of diabetic kidney disease: a focus on glucagon-like peptide 1 and dipeptidyl peptidase 4. Exp Physiol. 2014;99:1140-1145.
-
(2014)
Exp Physiol
, vol.99
, pp. 1140-1145
-
-
Vallon, V.1
Docherty, N.G.2
-
74
-
-
85028082197
-
Dipeptidyl peptidase 4 inhibition stimulates distal tubular natriuresis and increases in circulating SDF-1α1-67 in patients with type 2 diabetes
-
Lovshin JA, Rajasekeran H, Lytvyn Y, et al. Dipeptidyl peptidase 4 inhibition stimulates distal tubular natriuresis and increases in circulating SDF-1α1-67 in patients with type 2 diabetes. Diabetes Care. 2017;40:1073-1081.
-
(2017)
Diabetes Care
, vol.40
, pp. 1073-1081
-
-
Lovshin, J.A.1
Rajasekeran, H.2
Lytvyn, Y.3
-
75
-
-
84997428811
-
Stromal cell-derived factor-1 is upregulated by dipeptidyl peptidase-4 inhibition and has protective roles in progressive diabetic nephropathy
-
Takashima S, Fujita H, Fujishima H, et al. Stromal cell-derived factor-1 is upregulated by dipeptidyl peptidase-4 inhibition and has protective roles in progressive diabetic nephropathy. Kidney Int. 2016;90:783-796.
-
(2016)
Kidney Int
, vol.90
, pp. 783-796
-
-
Takashima, S.1
Fujita, H.2
Fujishima, H.3
-
76
-
-
85017582486
-
The potential and pitfalls of GLP-1 receptor agonists for renal protection in type 2 diabetes
-
Thomas MC. The potential and pitfalls of GLP-1 receptor agonists for renal protection in type 2 diabetes. Diabetes Metab. 2017;43(suppl 1):2S20-2S27.
-
(2017)
Diabetes Metab
, vol.43
, pp. 2S20-2S27
-
-
Thomas, M.C.1
-
77
-
-
84956596221
-
Mechanisms for the cardiovascular effects of glucagon-like peptide-1
-
Poudyal H. Mechanisms for the cardiovascular effects of glucagon-like peptide-1. Acta Physiol (Oxf). 2016;216:277-313.
-
(2016)
Acta Physiol (Oxf)
, vol.216
, pp. 277-313
-
-
Poudyal, H.1
-
78
-
-
84903266061
-
Sodium/glucose cotransporter 2 inhibitors and prevention of diabetic nephropathy: targeting the renal tubule in diabetes
-
De Nicola L, Gabbai FB, Liberti ME, Sagliocca A, Conte G, Minutolo R. Sodium/glucose cotransporter 2 inhibitors and prevention of diabetic nephropathy: targeting the renal tubule in diabetes. Am J Kidney Dis. 2014;64:16-24.
-
(2014)
Am J Kidney Dis
, vol.64
, pp. 16-24
-
-
De Nicola, L.1
Gabbai, F.B.2
Liberti, M.E.3
Sagliocca, A.4
Conte, G.5
Minutolo, R.6
-
79
-
-
84862875221
-
Effects of dapagliflozin, an SGLT2 inhibitor, on HbA(1c), body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy
-
Rosenstock J, Vico M, Wei L, Salsali A, List JF. Effects of dapagliflozin, an SGLT2 inhibitor, on HbA(1c), body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy. Diabetes Care. 2012;35:1473-1478.
-
(2012)
Diabetes Care
, vol.35
, pp. 1473-1478
-
-
Rosenstock, J.1
Vico, M.2
Wei, L.3
Salsali, A.4
List, J.F.5
-
80
-
-
84994476908
-
Impact of sodium-glucose cotransporter 2 inhibitors on blood pressure
-
Reed JW. Impact of sodium-glucose cotransporter 2 inhibitors on blood pressure. Vasc Health Risk Manag. 2016;12:393-405.
-
(2016)
Vasc Health Risk Manag
, vol.12
, pp. 393-405
-
-
Reed, J.W.1
-
81
-
-
84996486377
-
Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition
-
Vallon V, Thomson SC. Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition. Diabetologia. 2017;60:215-225.
-
(2017)
Diabetologia
, vol.60
, pp. 215-225
-
-
Vallon, V.1
Thomson, S.C.2
-
82
-
-
85018515017
-
Mechanism of the blood pressure-lowering effect of sodium-glucose cotransporter 2 inhibitors in obese patients with type 2 diabetes
-
Kawasoe S, Maruguchi Y, Kajiya S, et al. Mechanism of the blood pressure-lowering effect of sodium-glucose cotransporter 2 inhibitors in obese patients with type 2 diabetes. BMC Pharmacol Toxicol. 2017;18(1):23. https://doi.org/10.1186/s40360-017-0125-x.
-
(2017)
BMC Pharmacol Toxicol
, vol.18
, Issue.1
, pp. 23
-
-
Kawasoe, S.1
Maruguchi, Y.2
Kajiya, S.3
-
83
-
-
84897394040
-
Long-term study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control
-
Kohan DE, Fioretto P, Tang W, List JF. Long-term study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control. Kidney Int. 2014;85:962-971.
-
(2014)
Kidney Int
, vol.85
, pp. 962-971
-
-
Kohan, D.E.1
Fioretto, P.2
Tang, W.3
List, J.F.4
-
84
-
-
84903528312
-
Long-term treatment with the sodium glucose cotransporter 2 inhibitor, dapagliflozin, ameliorates glucose homeostasis and diabetic nephropathy in db/db mice
-
Terami N, Ogawa D, Tachibana H, et al. Long-term treatment with the sodium glucose cotransporter 2 inhibitor, dapagliflozin, ameliorates glucose homeostasis and diabetic nephropathy in db/db mice. PLoS One. 2014;9:e100777.
-
(2014)
PLoS One
, vol.9
-
-
Terami, N.1
Ogawa, D.2
Tachibana, H.3
-
85
-
-
84872400230
-
Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus
-
Vallon V, Rose M, Gerasimova M, et al. Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus. Am J Physiol Renal Physiol. 2013;304:F156-F167.
-
(2013)
Am J Physiol Renal Physiol
, vol.304
, pp. F156-F167
-
-
Vallon, V.1
Rose, M.2
Gerasimova, M.3
-
86
-
-
84255185190
-
Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat
-
Thomson SC, Rieg T, Miracle C, et al. Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat. Am J Physiol Regul Integr Comp Physiol. 2012;302:R75-R83.
-
(2012)
Am J Physiol Regul Integr Comp Physiol
, vol.302
, pp. R75-R83
-
-
Thomson, S.C.1
Rieg, T.2
Miracle, C.3
-
87
-
-
84905238756
-
The SGLT2 inhibitor empagliflozin ameliorates early features of diabetic nephropathy in BTBR ob/ob type 2 diabetic mice with and without hypertension
-
Gembardt F, Bartaun C, Jarzebska N, et al. The SGLT2 inhibitor empagliflozin ameliorates early features of diabetic nephropathy in BTBR ob/ob type 2 diabetic mice with and without hypertension. Am J Physiol Renal Physiol. 2014;307:F317-F325.
-
(2014)
Am J Physiol Renal Physiol
, vol.307
, pp. F317-F325
-
-
Gembardt, F.1
Bartaun, C.2
Jarzebska, N.3
-
88
-
-
84980320178
-
Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications
-
Heerspink HJ, Perkins BA, Fitchett DH, Husain M, Cherney DZ. Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications. Circulation. 2016;134:752-772.
-
(2016)
Circulation
, vol.134
, pp. 752-772
-
-
Heerspink, H.J.1
Perkins, B.A.2
Fitchett, D.H.3
Husain, M.4
Cherney, D.Z.5
-
89
-
-
84944800184
-
Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
-
Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015;373:2117-2128.
-
(2015)
N Engl J Med
, vol.373
, pp. 2117-2128
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
-
90
-
-
85023777061
-
Canagliflozin and cardiovascular and renal events in type 2 diabetes
-
Neal B, Perkovic V, Mahaffey KW, et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med. 2017;377:644-657. https://doi.org/10.1056/NEJMoa1611925.
-
(2017)
N Engl J Med
, vol.377
, pp. 644-657
-
-
Neal, B.1
Perkovic, V.2
Mahaffey, K.W.3
-
91
-
-
84975698839
-
Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME trial
-
Fitchett D, Zinman B, Wanner C, et al. Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME trial. Eur Heart J. 2016;37:1526-1534.
-
(2016)
Eur Heart J
, vol.37
, pp. 1526-1534
-
-
Fitchett, D.1
Zinman, B.2
Wanner, C.3
-
92
-
-
84975153660
-
The effect of sodium glucose cotransporter 2 inhibition with empagliflozin on microalbuminuria and macroalbuminuria in patients with type 2 diabetes
-
Cherney D, Lund SS, Perkins BA, et al. The effect of sodium glucose cotransporter 2 inhibition with empagliflozin on microalbuminuria and macroalbuminuria in patients with type 2 diabetes. Diabetologia. 2016;59:1860-1870.
-
(2016)
Diabetologia
, vol.59
, pp. 1860-1870
-
-
Cherney, D.1
Lund, S.S.2
Perkins, B.A.3
-
93
-
-
84919681923
-
Effect of canagliflozin on blood pressure and adverse events related to osmotic diuresis and reduced intravascular volume in patients with type 2 diabetes mellitus
-
Weir MR, Januszewicz A, Gilbert RE, et al. Effect of canagliflozin on blood pressure and adverse events related to osmotic diuresis and reduced intravascular volume in patients with type 2 diabetes mellitus. J Clin Hypertens (Greenwich). 2014;16:875-882.
-
(2014)
J Clin Hypertens (Greenwich)
, vol.16
, pp. 875-882
-
-
Weir, M.R.1
Januszewicz, A.2
Gilbert, R.E.3
-
94
-
-
84964507777
-
SGLT2 Inhibi-tion and cardiovascular events: why did EMPA-REG outcomes surprise and what were the likely mechanisms?
-
Sattar N, McLaren J, Kristensen SL, Preiss D, McMurray JJ. SGLT2 Inhibi-tion and cardiovascular events: why did EMPA-REG outcomes surprise and what were the likely mechanisms? Diabetologia. 2016;59:1333-1339.
-
(2016)
Diabetologia
, vol.59
, pp. 1333-1339
-
-
Sattar, N.1
McLaren, J.2
Kristensen, S.L.3
Preiss, D.4
McMurray, J.J.5
-
95
-
-
84898791440
-
Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes on background metformin and pioglitazone
-
Forst T, Guthrie R, Goldenberg R, et al. Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes on background metformin and pioglitazone. Diabetes Obes Metab. 2014;16:467-477.
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 467-477
-
-
Forst, T.1
Guthrie, R.2
Goldenberg, R.3
-
96
-
-
84991018034
-
Reappraisal of the diuretic effect of empagliflozin in the EMPA-REG OUTCOME trial: comparison with classic diuretics
-
Scheen AJ. Reappraisal of the diuretic effect of empagliflozin in the EMPA-REG OUTCOME trial: comparison with classic diuretics. Diabetes Metab. 2016;42:224-233.
-
(2016)
Diabetes Metab
, vol.42
, pp. 224-233
-
-
Scheen, A.J.1
-
97
-
-
84860783536
-
Dapagliflozin: a novel sodium-glucose cotransporter type 2 inhibitor for the treatment of type 2 diabetes mellitus
-
Shah NK, Deeb WE, Choksi R, Epstein BJ. Dapagliflozin: a novel sodium-glucose cotransporter type 2 inhibitor for the treatment of type 2 diabetes mellitus. Pharmacotherapy. 2012;32:80-94.
-
(2012)
Pharmacotherapy
, vol.32
, pp. 80-94
-
-
Shah, N.K.1
Deeb, W.E.2
Choksi, R.3
Epstein, B.J.4
-
98
-
-
0032707179
-
Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption
-
Vallon V, Richter K, Blantz RC, Thomson S, Osswald H. Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption. J Am Soc Nephrol. 1999;10:2569-2576.
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 2569-2576
-
-
Vallon, V.1
Richter, K.2
Blantz, R.C.3
Thomson, S.4
Osswald, H.5
-
99
-
-
0018858520
-
Hemodynamic changes during long-term thiazide treatment of essential hypertension in responders and nonresponders
-
van Brummelen P, Man in 't Veld AJ, Schalekamp MA. Hemodynamic changes during long-term thiazide treatment of essential hypertension in responders and nonresponders. Clin Pharmacol Ther. 1980;27:328-336.
-
(1980)
Clin Pharmacol Ther
, vol.27
, pp. 328-336
-
-
van Brummelen, P.1
Man in 't Veld, A.J.2
Schalekamp, M.A.3
-
100
-
-
0018891896
-
Body fluid volumes and the response of renin and aldosterone to short- and long-term thiazide therapy of essential hypertension
-
van Brummelen P, Schalekamp MA. Body fluid volumes and the response of renin and aldosterone to short- and long-term thiazide therapy of essential hypertension. Acta Med Scand. 1980;207:259-264.
-
(1980)
Acta Med Scand
, vol.207
, pp. 259-264
-
-
van Brummelen, P.1
Schalekamp, M.A.2
-
101
-
-
0027243453
-
Comparative effects of different antihypertensive treatments on progression of diabetic renal disease
-
Slataper R, Vicknair N, Sadler R, Bakris GL. Comparative effects of different antihypertensive treatments on progression of diabetic renal disease. Arch Intern Med. 1993;153:973-980.
-
(1993)
Arch Intern Med
, vol.153
, pp. 973-980
-
-
Slataper, R.1
Vicknair, N.2
Sadler, R.3
Bakris, G.L.4
-
102
-
-
0027082683
-
Blood pressure disturbance in diabetes mellitus
-
Zanella MT, Freire MB, Milagres R, et al. Blood pressure disturbance in diabetes mellitus. J Hypertens. 1992;10(suppl):S59-S70.
-
(1992)
J Hypertens
, vol.10
, pp. S59-S70
-
-
Zanella, M.T.1
Freire, M.B.2
Milagres, R.3
-
103
-
-
33644546432
-
Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting
-
Calado J, Loeffler J, Sakallioglu O, et al. Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting. Kidney Int. 2006;69:852-855.
-
(2006)
Kidney Int
, vol.69
, pp. 852-855
-
-
Calado, J.1
Loeffler, J.2
Sakallioglu, O.3
-
104
-
-
78651406659
-
SGLT2 mediates glucose reabsorption in the early proximal tubule
-
Vallon V, Platt KA, Cunard R, et al. SGLT2 mediates glucose reabsorption in the early proximal tubule. J Am Soc Nephrol. 2011;22:104-112.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 104-112
-
-
Vallon, V.1
Platt, K.A.2
Cunard, R.3
-
105
-
-
84921374693
-
Functional role of glucose metabolism, osmotic stress, and sodium-glucose cotransporter isoform-mediated transport on Na+/H+ exchanger isoform 3 activity in the renal proximal tubule
-
Pessoa TD, Campos LC, Carraro-Lacroix L, Girardi AC, Malnic G. Functional role of glucose metabolism, osmotic stress, and sodium-glucose cotransporter isoform-mediated transport on Na+/H+ exchanger isoform 3 activity in the renal proximal tubule. J Am Soc Nephrol. 2014;25:2028-2039.
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 2028-2039
-
-
Pessoa, T.D.1
Campos, L.C.2
Carraro-Lacroix, L.3
Girardi, A.C.4
Malnic, G.5
-
106
-
-
85021851549
-
MAP17 is a necessary activator of renal Na+/glucose cotransporter SGLT2
-
Coady MJ, El Tarazi A, Santer R, et al. MAP17 is a necessary activator of renal Na+/glucose cotransporter SGLT2. J Am Soc Nephrol. 2017;28:85-93.
-
(2017)
J Am Soc Nephrol
, vol.28
, pp. 85-93
-
-
Coady, M.J.1
El Tarazi, A.2
Santer, R.3
-
107
-
-
84923388220
-
SGLT2 inhibitor empagliflozin increases renal NHE3 phosphorylation in diabetic Akita mice: possible implications for the prevention of glomerular hyperfiltration
-
Fu Y, Gerasimova M, Mayoux E, et al. SGLT2 inhibitor empagliflozin increases renal NHE3 phosphorylation in diabetic Akita mice: possible implications for the prevention of glomerular hyperfiltration. Diabetes. 2014;63(suppl 1):A132.
-
(2014)
Diabetes
, vol.63
, pp. A132
-
-
Fu, Y.1
Gerasimova, M.2
Mayoux, E.3
-
108
-
-
84991712516
-
Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits
-
Baartscheer A, Schumacher CA, Wüst RC, et al. Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits. Diabetologia. 2017;60:568-573.
-
(2017)
Diabetologia
, vol.60
, pp. 568-573
-
-
Baartscheer, A.1
Schumacher, C.A.2
Wüst, R.C.3
-
109
-
-
85040781177
-
SGLT2 inhibitors inhibit NHE-1, lower [Na+]c and induced vasodilation, but only empaglilozin increases oxygen and glucose consumption in isolated mouse hearts
-
June 13,, San Diego
-
Uthman L, Baartscheer A, Schumacher CA, et al. SGLT2 inhibitors inhibit NHE-1, lower [Na+]c and induced vasodilation, but only empaglilozin increases oxygen and glucose consumption in isolated mouse hearts. Presented at the American Diabetes Association Meeting; June 13, 2017; San Diego.
-
(2017)
Presented at the American Diabetes Association Meeting
-
-
Uthman, L.1
Baartscheer, A.2
Schumacher, C.A.3
-
110
-
-
85019618220
-
The SGLT2 inhibitor dapagliflozin prevents cardiomyopathy in a diabetic lipodystrophic mouse model
-
Joubert M, Jagu B, Montaigne D, et al. The SGLT2 inhibitor dapagliflozin prevents cardiomyopathy in a diabetic lipodystrophic mouse model. Diabetes. 2017;66(4):1030-1040. https://doi.org/10.2337/db16-0733.
-
(2017)
Diabetes
, vol.66
, Issue.4
, pp. 1030-1040
-
-
Joubert, M.1
Jagu, B.2
Montaigne, D.3
-
111
-
-
84995969879
-
Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome
-
Kusaka H, Koibuchi N, Hasegawa Y, Ogawa H, Kim-Mitsuyama S. Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome. Cardiovasc Diabetol. 2016;15:157.
-
(2016)
Cardiovasc Diabetol
, vol.15
, pp. 157
-
-
Kusaka, H.1
Koibuchi, N.2
Hasegawa, Y.3
Ogawa, H.4
Kim-Mitsuyama, S.5
-
112
-
-
85032620814
-
Effects of sodium-glucose cotransporter 2 inhibitors for the treatment of patients with heart failure: proposal of a novel mechanism of action
-
Packer M, Anker SD, Butler J, Filippatos G, Zannad F. Effects of sodium-glucose cotransporter 2 inhibitors for the treatment of patients with heart failure: proposal of a novel mechanism of action. JAMA Cardiol. 2017;2(9):1025-1029. https://doi.org/10.1001/jamacardio.2017.2275.
-
(2017)
JAMA Cardiol
, vol.2
, Issue.9
, pp. 1025-1029
-
-
Packer, M.1
Anker, S.D.2
Butler, J.3
Filippatos, G.4
Zannad, F.5
-
113
-
-
33846362954
-
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system
-
Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol. 2007;292:C82-C97.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
, pp. C82-C97
-
-
Mehta, P.K.1
Griendling, K.K.2
-
114
-
-
84968772300
-
Angiotensin-(1-7): a novel peptide to treat hypertension and nephropathy in diabetes?
-
Padda RS, Shi Y, Lo CS, Zhang SL, Chan JS. Angiotensin-(1-7): a novel peptide to treat hypertension and nephropathy in diabetes? J Diabetes Metab. 2015;6. https://doi.org/10.4172/2155-6156.1000615.
-
(2015)
J Diabetes Metab
, vol.6
-
-
Padda, R.S.1
Shi, Y.2
Lo, C.S.3
Zhang, S.L.4
Chan, J.S.5
-
115
-
-
84928929919
-
Angiotensin-(1-7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice
-
Shi Y, Lo CS, Padda R, et al. Angiotensin-(1-7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice. Clin Sci (Lond). 2015;128:649-663.
-
(2015)
Clin Sci (Lond)
, vol.128
, pp. 649-663
-
-
Shi, Y.1
Lo, C.S.2
Padda, R.3
-
116
-
-
84922252826
-
Angiotensin(1-7) attenuates the progression of streptozotocin-induced diabetic renal injury better than angiotensin receptor blockade
-
Zhang K, Meng X, Li D, et al. Angiotensin(1-7) attenuates the progression of streptozotocin-induced diabetic renal injury better than angiotensin receptor blockade. Kidney Int. 2015;87:359-369.
-
(2015)
Kidney Int
, vol.87
, pp. 359-369
-
-
Zhang, K.1
Meng, X.2
Li, D.3
-
117
-
-
77449160523
-
Human recombinant ACE2 reduces the progression of diabetic nephropathy
-
Oudit GY, Liu GC, Zhong J, et al. Human recombinant ACE2 reduces the progression of diabetic nephropathy. Diabetes. 2010;59:529-538.
-
(2010)
Diabetes
, vol.59
, pp. 529-538
-
-
Oudit, G.Y.1
Liu, G.C.2
Zhong, J.3
-
118
-
-
84896859922
-
Activation of angiotensin type 2 receptors partially ameliorates streptozotocin-induced diabetes in male rats by islet protection
-
Shao C, Yu L, Gao L. Activation of angiotensin type 2 receptors partially ameliorates streptozotocin-induced diabetes in male rats by islet protection. Endocrinology. 2014;155:793-804.
-
(2014)
Endocrinology
, vol.155
, pp. 793-804
-
-
Shao, C.1
Yu, L.2
Gao, L.3
-
120
-
-
84930989439
-
AT2R agonist, compound 21, is renoprotective against type 1 diabetic nephropathy
-
Koulis C, Chow BS, McKelvey M, et al. AT2R agonist, compound 21, is renoprotective against type 1 diabetic nephropathy. Hypertension. 2015;65:1073-1081.
-
(2015)
Hypertension
, vol.65
, pp. 1073-1081
-
-
Koulis, C.1
Chow, B.S.2
McKelvey, M.3
-
121
-
-
0035818501
-
Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse
-
Huang W, Gallois Y, Bouby N, et al. Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse. Proc Natl Acad Sci U S A. 2001;98:13330-13334.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13330-13334
-
-
Huang, W.1
Gallois, Y.2
Bouby, N.3
-
122
-
-
40849127119
-
Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls
-
Mizuiri S, Hemmi H, Arita M, et al. Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls. Am J Kidney Dis. 2008;51:613-623.
-
(2008)
Am J Kidney Dis
, vol.51
, pp. 613-623
-
-
Mizuiri, S.1
Hemmi, H.2
Arita, M.3
-
123
-
-
57049086924
-
Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease
-
Reich HN, Oudit GY, Penninger JM, Scholey JW, Herzenberg AM. Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease. Kidney Int. 2008;74(12):1610-1616. https://doi.org/10.1038/ki.2008.497.
-
(2008)
Kidney Int
, vol.74
, Issue.12
, pp. 1610-1616
-
-
Reich, H.N.1
Oudit, G.Y.2
Penninger, J.M.3
Scholey, J.W.4
Herzenberg, A.M.5
-
124
-
-
0027517659
-
The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group
-
Lewis EJ, Hunsicker LG, Bain RP, Rohde RD. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. N Engl J Med. 1993;329:1456-1462.
-
(1993)
N Engl J Med
, vol.329
, pp. 1456-1462
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Bain, R.P.3
Rohde, R.D.4
-
125
-
-
0035922447
-
Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
-
Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med. 2001;345:851-860.
-
(2001)
N Engl J Med
, vol.345
, pp. 851-860
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Clarke, W.R.3
-
126
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001;345:861-869.
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
de Zeeuw, D.3
-
127
-
-
84983372741
-
Protection against death and renal failure by renin-angiotensin system blockers in patients with diabetes and kidney disease
-
Shen J, Huang YM, Song XN, et al. Protection against death and renal failure by renin-angiotensin system blockers in patients with diabetes and kidney disease. J Renin Angiotensin Aldosterone Syst. 2016;17(3):pii: 1470320316656481.
-
(2016)
J Renin Angiotensin Aldosterone Syst
, vol.17
, Issue.3
-
-
Shen, J.1
Huang, Y.M.2
Song, X.N.3
-
128
-
-
84962068631
-
Cardiovascular and renal outcomes of renin-angiotensin system blockade in adult patients with diabetes mellitus: a systematic review with network meta-analyses
-
Catalá-López F, Macías Saint-Gerons D, González-Bermejo D, et al. Cardiovascular and renal outcomes of renin-angiotensin system blockade in adult patients with diabetes mellitus: a systematic review with network meta-analyses. PLoS Med. 2016;13(3):e1001971.
-
(2016)
PLoS Med
, vol.13
, Issue.3
-
-
Catalá-López, F.1
Macías Saint-Gerons, D.2
González-Bermejo, D.3
-
129
-
-
79961132281
-
Angiotensin II-mediated biphasic regulation of proximal tubular Na+/H+ exchanger 3 is impaired during oxidative stress
-
Banday AA, Lokhandwala MF. Angiotensin II-mediated biphasic regulation of proximal tubular Na+/H+ exchanger 3 is impaired during oxidative stress. Am J Physiol Renal Physiol. 2011;301:F364-F370.
-
(2011)
Am J Physiol Renal Physiol
, vol.301
, pp. F364-F370
-
-
Banday, A.A.1
Lokhandwala, M.F.2
-
130
-
-
77956243677
-
Activation of Na+/H+ exchanger NHE3 by angiotensin II is mediated by inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3 (IRBIT) and Ca2+/calmodulin-dependent protein kinase II
-
He P, Klein J, Yun CC. Activation of Na+/H+ exchanger NHE3 by angiotensin II is mediated by inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3 (IRBIT) and Ca2+/calmodulin-dependent protein kinase II. J Biol Chem. 2010;285:27869-27878.
-
(2010)
J Biol Chem
, vol.285
, pp. 27869-27878
-
-
He, P.1
Klein, J.2
Yun, C.C.3
-
131
-
-
33646802312
-
Regulation of Na+/H+ exchanger-NHE3 by angiotensin-II in OKP cells
-
Xu L, Dixit MP, Nullmeyer KD, et al. Regulation of Na+/H+ exchanger-NHE3 by angiotensin-II in OKP cells. Biochim Biophys Acta. 2006;1758:519-526.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 519-526
-
-
Xu, L.1
Dixit, M.P.2
Nullmeyer, K.D.3
-
132
-
-
78149425568
-
Regulation of Na+/H+ exchanger isoform 1 (NHE1) by calmodulin-binding sites: role of angiotensin II
-
Eguti DM, Thieme K, Leung GP, Mello-Aires M, Oliveira-Souza M. Regulation of Na+/H+ exchanger isoform 1 (NHE1) by calmodulin-binding sites: role of angiotensin II. Cell Physiol Biochem. 2010;26:541-552.
-
(2010)
Cell Physiol Biochem
, vol.26
, pp. 541-552
-
-
Eguti, D.M.1
Thieme, K.2
Leung, G.P.3
Mello-Aires, M.4
Oliveira-Souza, M.5
-
133
-
-
84977661289
-
Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines
-
Li XC, Shull GE, Miguel-Qin E, Chen F, Zhuo JL. Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines. Physiol Rep. 2015;3(11):pii: e12605.
-
(2015)
Physiol Rep
, vol.3
, Issue.11
-
-
Li, X.C.1
Shull, G.E.2
Miguel-Qin, E.3
Chen, F.4
Zhuo, J.L.5
-
134
-
-
84986562939
-
Short-term nonpressor angiotensin II infusion stimulates sodium transporters in proximal tubule and distal nephron
-
Nguyen MT, Han J, Ralph DL, Veiras LC, McDonough AA. Short-term nonpressor angiotensin II infusion stimulates sodium transporters in proximal tubule and distal nephron. Physiol Rep. 2015;3(9):pii: e12496.
-
(2015)
Physiol Rep
, vol.3
, Issue.9
-
-
Nguyen, M.T.1
Han, J.2
Ralph, D.L.3
Veiras, L.C.4
McDonough, A.A.5
-
135
-
-
77949801479
-
Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure
-
McDonough AA. Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure. Am J Physiol Regul Integr Comp Physiol. 2010;298:R851-RR61.
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.298
, pp. 851-861
-
-
McDonough, A.A.1
-
136
-
-
71449103039
-
Changes of renal AQP2, ENaC, and NHE3 in experimentally induced heart failure: response to angiotensin II AT1 receptor blockade
-
Lütken SC, Kim SW, Jonassen T, et al. Changes of renal AQP2, ENaC, and NHE3 in experimentally induced heart failure: response to angiotensin II AT1 receptor blockade. Am J Physiol Renal Physiol. 2009;297:F1678-F1688.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F1678-F1688
-
-
Lütken, S.C.1
Kim, S.W.2
Jonassen, T.3
-
137
-
-
3042542021
-
Effect of angiotensin-II on renal Na+/H+ exchanger-NHE3 and NHE2
-
Dixit MP, Xu L, Xu H, Bai L, Collins JF, Ghishan FK. Effect of angiotensin-II on renal Na+/H+ exchanger-NHE3 and NHE2. Biochim Biophys Acta. 2004;1664:38-44.
-
(2004)
Biochim Biophys Acta
, vol.1664
, pp. 38-44
-
-
Dixit, M.P.1
Xu, L.2
Xu, H.3
Bai, L.4
Collins, J.F.5
Ghishan, F.K.6
-
138
-
-
44449179352
-
The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells
-
Stevens VA, Saad S, Poronnik P, Fenton-Lee CA, Polhill TS, Pollock CA. The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells. Nephrol Dial Transplant. 2008;23:1834-1843.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 1834-1843
-
-
Stevens, V.A.1
Saad, S.2
Poronnik, P.3
Fenton-Lee, C.A.4
Polhill, T.S.5
Pollock, C.A.6
-
139
-
-
84929659869
-
Crosstalk between the renal sympathetic nerve and intrarenal angiotensin II modulates proximal tubular sodium reabsorption
-
Pontes RB, Girardi AC, Nishi EE, Campos RR, Bergamaschi CT. Crosstalk between the renal sympathetic nerve and intrarenal angiotensin II modulates proximal tubular sodium reabsorption. Exp Physiol. 2015;100:502-506.
-
(2015)
Exp Physiol
, vol.100
, pp. 502-506
-
-
Pontes, R.B.1
Girardi, A.C.2
Nishi, E.E.3
Campos, R.R.4
Bergamaschi, C.T.5
-
141
-
-
84890124294
-
3 activity by angiotensin II is mediated by the activation of the angiotensin II type I receptor/phospholipase C/calcium/cal-modulin pathway in distal nephron cells
-
3 activity by angiotensin II is mediated by the activation of the angiotensin II type I receptor/phospholipase C/calcium/cal-modulin pathway in distal nephron cells. Eur J Pharmacol. 2013;721:322-331.
-
(2013)
Eur J Pharmacol
, vol.721
, pp. 322-331
-
-
Costa-Pessoa, J.M.1
Figueiredo, C.F.2
Thieme, K.3
Oliveira-Souza, M.4
-
142
-
-
84878667060
-
Dose-dependent effects of angiotensin-(1-7) on the NHE3 exchanger and [Ca(2+)](i) in in vivo proximal tubules
-
Castelo-Branco RC, Leite-Delova DC, de Mello-Aires M. Dose-dependent effects of angiotensin-(1-7) on the NHE3 exchanger and [Ca(2+)](i) in in vivo proximal tubules. Am J Physiol Renal Physiol. 2013;304:F1258-F1265.
-
(2013)
Am J Physiol Renal Physiol
, vol.304
, pp. F1258-F1265
-
-
Castelo-Branco, R.C.1
Leite-Delova, D.C.2
de Mello-Aires, M.3
-
143
-
-
84907212771
-
Novel mechanism of intra-renal angiotensin II-induced sodium/proton exchanger 3 expression by losartan in spontaneously hypertensive rats
-
Fan X, Liu K, Cui W, Huang J, Wang W, Gao Y. Novel mechanism of intra-renal angiotensin II-induced sodium/proton exchanger 3 expression by losartan in spontaneously hypertensive rats. Mol Med Rep. 2014;10:2483-2488.
-
(2014)
Mol Med Rep
, vol.10
, pp. 2483-2488
-
-
Fan, X.1
Liu, K.2
Cui, W.3
Huang, J.4
Wang, W.5
Gao, Y.6
-
144
-
-
35348817994
-
Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance
-
Yang LE, Leong PK, McDonough AA. Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance. Am J Physiol Renal Physiol. 2007;293:F1197-F1208.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. F1197-F1208
-
-
Yang, L.E.1
Leong, P.K.2
McDonough, A.A.3
-
146
-
-
84871213936
-
Renal hyperfiltration related to diabetes mellitus and obesity in human disease
-
Sasson AN, Cherney DZ. Renal hyperfiltration related to diabetes mellitus and obesity in human disease. World J Diabetes. 2012;3:1-6.
-
(2012)
World J Diabetes
, vol.3
, pp. 1-6
-
-
Sasson, A.N.1
Cherney, D.Z.2
-
147
-
-
84907087561
-
Angiotensin-neprilysin inhibition versus enalapril in heart failure
-
McMurray JJ, Packer M, Desai AS, et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014;371:993-1004.
-
(2014)
N Engl J Med
, vol.371
, pp. 993-1004
-
-
McMurray, J.J.1
Packer, M.2
Desai, A.S.3
-
148
-
-
84955319328
-
Risk related to pre-diabetes mellitus and diabetes mellitus in heart failure With reduced ejection fraction: insights from Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure trial
-
Kristensen SL, Preiss D, Jhund PS, et al. Risk related to pre-diabetes mellitus and diabetes mellitus in heart failure With reduced ejection fraction: insights from Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure trial. Circ Heart Fail. 2016;9(1):pii:e002560.
-
(2016)
Circ Heart Fail
, vol.9
, Issue.1
-
-
Kristensen, S.L.1
Preiss, D.2
Jhund, P.S.3
-
149
-
-
85007440122
-
Importance of endogenous compensatory vaso-active peptides in broadening the effects of inhibitors of the renin-angiotensin system for the treatment of heart failure
-
Packer M, McMurray JJV. Importance of endogenous compensatory vaso-active peptides in broadening the effects of inhibitors of the renin-angiotensin system for the treatment of heart failure. Lancet. 2017;389:1831-1840.
-
(2017)
Lancet
, vol.389
, pp. 1831-1840
-
-
Packer, M.1
McMurray, J.J.V.2
-
150
-
-
0029058341
-
Effect of atrial natriuretic peptide on renal and vascular permeability in diabetes mellitus
-
Zietse R, Derkx FH, Weimar W, Schalekamp MA. Effect of atrial natriuretic peptide on renal and vascular permeability in diabetes mellitus. J Am Soc Nephrol. 1995;5:2057-2066.
-
(1995)
J Am Soc Nephrol
, vol.5
, pp. 2057-2066
-
-
Zietse, R.1
Derkx, F.H.2
Weimar, W.3
Schalekamp, M.A.4
-
151
-
-
0023377922
-
Atrial natriuretic peptide and the kidney
-
Ballermann BJ, Brenner BM. Atrial natriuretic peptide and the kidney. Am J Kidney Dis. 1987;10(suppl 1):7-12.
-
(1987)
Am J Kidney Dis
, vol.10
, pp. 7-12
-
-
Ballermann, B.J.1
Brenner, B.M.2
-
152
-
-
0028375948
-
Effects of an atrial natriuretic peptide receptor antagonist on glomerular hyperfiltration in diabetic rats
-
Zhang PL, Mackenzie HS, Troy JL, Brenner BM. Effects of an atrial natriuretic peptide receptor antagonist on glomerular hyperfiltration in diabetic rats. J Am Soc Nephrol. 1994;4:1564-1570.
-
(1994)
J Am Soc Nephrol
, vol.4
, pp. 1564-1570
-
-
Zhang, P.L.1
Mackenzie, H.S.2
Troy, J.L.3
Brenner, B.M.4
-
153
-
-
0032993031
-
Atrial natriuretic peptide increases albuminuria in type I diabetic patients: evidence for blockade of tubular protein reabsorption
-
Jacobs EM, Vervoort G, Branten AJ, Klasen I, Smits P, Wetzels JF. Atrial natriuretic peptide increases albuminuria in type I diabetic patients: evidence for blockade of tubular protein reabsorption. Eur J Clin Invest. 1999;29:109-115.
-
(1999)
Eur J Clin Invest
, vol.29
, pp. 109-115
-
-
Jacobs, E.M.1
Vervoort, G.2
Branten, A.J.3
Klasen, I.4
Smits, P.5
Wetzels, J.F.6
-
154
-
-
0036283432
-
Atrial natriuretic peptide-induced microalbuminuria is associated with endothelial dysfunction in noncomplicated type 1 diabetes patients
-
Vervoort G, Wetzels JF, Lutterman JA, Bravenboer B, Berden JH, Smits P. Atrial natriuretic peptide-induced microalbuminuria is associated with endothelial dysfunction in noncomplicated type 1 diabetes patients. Am J Kidney Dis. 2002;40:9-15.
-
(2002)
Am J Kidney Dis
, vol.40
, pp. 9-15
-
-
Vervoort, G.1
Wetzels, J.F.2
Lutterman, J.A.3
Bravenboer, B.4
Berden, J.H.5
Smits, P.6
-
155
-
-
0037143601
-
Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE)
-
Packer M, Califf RM, Konstam MA, et al. Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE). Circulation. 2002;106:920-926.
-
(2002)
Circulation
, vol.106
, pp. 920-926
-
-
Packer, M.1
Califf, R.M.2
Konstam, M.A.3
-
156
-
-
0034686963
-
Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial
-
Rouleau JL, Pfeffer MA, Stewart DJ, et al. Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial. Lancet. 2000;356:615-620.
-
(2000)
Lancet
, vol.356
, pp. 615-620
-
-
Rouleau, J.L.1
Pfeffer, M.A.2
Stewart, D.J.3
-
157
-
-
84928609455
-
Renal effects of the angiotensin receptor neprilysin inhibitor LCZ696 in patients with heart failure and preserved ejection fraction
-
Voors AA, Gori M, Liu LC, et al. Renal effects of the angiotensin receptor neprilysin inhibitor LCZ696 in patients with heart failure and preserved ejection fraction. Eur J Heart Fail. 2015;17:510-517.
-
(2015)
Eur J Heart Fail
, vol.17
, pp. 510-517
-
-
Voors, A.A.1
Gori, M.2
Liu, L.C.3
-
158
-
-
0031915399
-
Effect of BNP on renal hemodynamics, tubular function and vasoactive hormones in humans
-
Jensen KT, Carstens J, Pedersen EB. Effect of BNP on renal hemodynamics, tubular function and vasoactive hormones in humans. Am J Physiol. 1998;274:F63-F72.
-
(1998)
Am J Physiol
, vol.274
, pp. F63-F72
-
-
Jensen, K.T.1
Carstens, J.2
Pedersen, E.B.3
-
159
-
-
0029779330
-
Renal and hormonal actions of atrial natriuretic peptide during angiotensin II or noradrenaline infusion in man
-
Eiskjaer H, Nielsen CB, Sørensen SS, Pedersen EB. Renal and hormonal actions of atrial natriuretic peptide during angiotensin II or noradrenaline infusion in man. Eur J Clin Invest. 1996;26:584-595.
-
(1996)
Eur J Clin Invest
, vol.26
, pp. 584-595
-
-
Eiskjaer, H.1
Nielsen, C.B.2
Sørensen, S.S.3
Pedersen, E.B.4
-
160
-
-
0028273520
-
Cardiovascular and renal effects of low dose brain natriuretic peptide infusion in man
-
La Villa G, Fronzaroli C, Lazzeri C, et al. Cardiovascular and renal effects of low dose brain natriuretic peptide infusion in man. J Clin Endocrinol Metab. 1994;78:1166-1171.
-
(1994)
J Clin Endocrinol Metab
, vol.78
, pp. 1166-1171
-
-
La Villa, G.1
Fronzaroli, C.2
Lazzeri, C.3
-
161
-
-
0027492174
-
Dose-response study of atrial natriuretic peptide bolus injection in healthy man
-
Eiskjaer H, Pedersen EB. Dose-response study of atrial natriuretic peptide bolus injection in healthy man. Eur J Clin Invest. 1993;23:37-45.
-
(1993)
Eur J Clin Invest
, vol.23
, pp. 37-45
-
-
Eiskjaer, H.1
Pedersen, E.B.2
-
162
-
-
0025285642
-
Role of renal interstitial hydrostatic pressure in natriuretic response to ANP
-
García-Estañ J, Roman RJ. Role of renal interstitial hydrostatic pressure in natriuretic response to ANP. Am J Physiol. 1990;258:R1333-R1339.
-
(1990)
Am J Physiol
, vol.258
, pp. R1333-R1339
-
-
García-Estañ, J.1
Roman, R.J.2
-
163
-
-
0023775716
-
Effect of low dose infusion of atrial natriuretic peptide on renal function in man
-
Solomon LR, Atherton JC, Bobinski H, Hillier V, Green R. Effect of low dose infusion of atrial natriuretic peptide on renal function in man. Clin Sci (Lond). 1988;75:403-410.
-
(1988)
Clin Sci (Lond)
, vol.75
, pp. 403-410
-
-
Solomon, L.R.1
Atherton, J.C.2
Bobinski, H.3
Hillier, V.4
Green, R.5
-
164
-
-
0023628410
-
Site of the action of a synthetic atrial natriuretic peptide evaluated in humans
-
Biollaz J, Bidiville J, Diézi J, et al. Site of the action of a synthetic atrial natriuretic peptide evaluated in humans. Kidney Int. 1987;32:537-546.
-
(1987)
Kidney Int
, vol.32
, pp. 537-546
-
-
Biollaz, J.1
Bidiville, J.2
Diézi, J.3
-
165
-
-
0023272139
-
Atrial natriuretic peptide inhibits angiotensin-stimulated proximal tubular sodium and water reabsorption
-
Harris PJ, Thomas D, Morgan TO. Atrial natriuretic peptide inhibits angiotensin-stimulated proximal tubular sodium and water reabsorption. Nature. 1987;326:697-698.
-
(1987)
Nature
, vol.326
, pp. 697-698
-
-
Harris, P.J.1
Thomas, D.2
Morgan, T.O.3
-
166
-
-
0037269041
-
Cyclic GMP mediates influence of macula densa nitric oxide over tubuloglomerular feedback
-
Thomson SC, Deng A. Cyclic GMP mediates influence of macula densa nitric oxide over tubuloglomerular feedback. Kidney Blood Press Res. 2003;26:10-18.
-
(2003)
Kidney Blood Press Res
, vol.26
, pp. 10-18
-
-
Thomson, S.C.1
Deng, A.2
-
167
-
-
0036021809
-
Hormonal, renal, hemodynamic responses to acute neutral endopeptidase inhibition in heart transplant patients
-
Piquard F, Richard R, Charloux A, et al. Hormonal, renal, hemodynamic responses to acute neutral endopeptidase inhibition in heart transplant patients. J Appl Physiol (1985). 2002;93:569-575.
-
(2002)
J Appl Physiol (1985)
, vol.93
, pp. 569-575
-
-
Piquard, F.1
Richard, R.2
Charloux, A.3
-
168
-
-
29244450147
-
Anti-atherosclerotic and renoprotective effects of combined angiotensin-converting enzyme and neutral endopeptidase inhibi-tion in diabetic apolipoprotein E-knockout mice
-
Jandeleit-Dahm K, Lassila M, Davis BJ, et al. Anti-atherosclerotic and renoprotective effects of combined angiotensin-converting enzyme and neutral endopeptidase inhibi-tion in diabetic apolipoprotein E-knockout mice. J Hypertens. 2005;23:2071-2082.
-
(2005)
J Hypertens
, vol.23
, pp. 2071-2082
-
-
Jandeleit-Dahm, K.1
Lassila, M.2
Davis, B.J.3
-
169
-
-
0041903652
-
Renoprotective effects of vasopeptidase inhibition in an experimental model of diabetic nephropathy
-
Davis BJ, Johnston CI, Burrell LM, et al. Renoprotective effects of vasopeptidase inhibition in an experimental model of diabetic nephropathy. Diabetologia. 2003;46:961-971.
-
(2003)
Diabetologia
, vol.46
, pp. 961-971
-
-
Davis, B.J.1
Johnston, C.I.2
Burrell, L.M.3
-
170
-
-
85014114230
-
Blood pressure-independent renoprotection in diabetic rats treated with AT1 receptor-neprilysin inhibition compared with AT1 receptor blockade alone
-
Roksnoer LC, van Veghel R, van Groningen MC, et al. Blood pressure-independent renoprotection in diabetic rats treated with AT1 receptor-neprilysin inhibition compared with AT1 receptor blockade alone. Clin Sci (Lond). 2016;130:1209-1220.
-
(2016)
Clin Sci (Lond)
, vol.130
, pp. 1209-1220
-
-
Roksnoer, L.C.1
van Veghel, R.2
van Groningen, M.C.3
-
171
-
-
0034838230
-
Vasopeptidase inhibition affords greater renoprotection than angiotensin-converting enzyme inhibition alone
-
Taal MW, Nenov VD, Wong W, et al. Vasopeptidase inhibition affords greater renoprotection than angiotensin-converting enzyme inhibition alone. J Am Soc Nephrol. 2001;12:2051-2059.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 2051-2059
-
-
Taal, M.W.1
Nenov, V.D.2
Wong, W.3
-
172
-
-
0036714518
-
Renal hemodynamic and natriuretic effects of concomitant angiotensin-converting enzyme and neutral endopeptidase inhibition in men
-
Regamey F, Maillard M, Nussberger J, Brunner HR, Burnier M. Renal hemodynamic and natriuretic effects of concomitant angiotensin-converting enzyme and neutral endopeptidase inhibition in men. Hypertension. 2002;40:266-272.
-
(2002)
Hypertension
, vol.40
, pp. 266-272
-
-
Regamey, F.1
Maillard, M.2
Nussberger, J.3
Brunner, H.R.4
Burnier, M.5
-
173
-
-
84995452430
-
Effects of sacubitril/valsartan (LCZ696) on natriuresis, diuresis, blood pressures, and NT-proBNP in salt-sensitive hypertension
-
Wang TD, Tan RS, Lee HY, et al. Effects of sacubitril/valsartan (LCZ696) on natriuresis, diuresis, blood pressures, and NT-proBNP in salt-sensitive hypertension. Hypertension. 2017;69:32-41.
-
(2017)
Hypertension
, vol.69
, pp. 32-41
-
-
Wang, T.D.1
Tan, R.S.2
Lee, H.Y.3
-
174
-
-
0029150815
-
Systemic hemodynamics and renal function during brain natriuretic peptide infusion in patients with essential hypertension
-
Lazzeri C, Franchi F, Porciani C, et al. Systemic hemodynamics and renal function during brain natriuretic peptide infusion in patients with essential hypertension. Am J Hypertens. 1995;8:799-807.
-
(1995)
Am J Hypertens
, vol.8
, pp. 799-807
-
-
Lazzeri, C.1
Franchi, F.2
Porciani, C.3
-
175
-
-
0030899806
-
Control of proximal tubule acidification by the endothelium of the peritubular capillaries
-
Amorena C, Castro AF. Control of proximal tubule acidification by the endothelium of the peritubular capillaries. Am J Physiol. 1997;272:R691-R694.
-
(1997)
Am J Physiol
, vol.272
, pp. R691-R694
-
-
Amorena, C.1
Castro, A.F.2
-
176
-
-
20444441935
-
cGMP inhibition of Na+/H+ antiporter 3 (NHE3) requires PDZ domain adapter NHERF2, a broad specificity protein kinase G-anchoring protein
-
Cha B, Kim JH, Hut H, et al. cGMP inhibition of Na+/H+ antiporter 3 (NHE3) requires PDZ domain adapter NHERF2, a broad specificity protein kinase G-anchoring protein. J Biol Chem. 2005;280:16642-16650.
-
(2005)
J Biol Chem
, vol.280
, pp. 16642-16650
-
-
Cha, B.1
Kim, J.H.2
Hut, H.3
-
177
-
-
0035571917
-
Renal interstitial cGMP mediates natriuresis by direct tubule mechanism
-
Jin XH, Siragy HM, Carey RM. Renal interstitial cGMP mediates natriuresis by direct tubule mechanism. Hypertension. 2001;38:309-316.
-
(2001)
Hypertension
, vol.38
, pp. 309-316
-
-
Jin, X.H.1
Siragy, H.M.2
Carey, R.M.3
-
178
-
-
0942268856
-
Chronic nitric oxide synthase inhibition exacerbates renal dysfunction in cirrhotic rats
-
Graebe M, Brond L, Christensen S, Nielsen S, Olsen NV, Jonassen TE. Chronic nitric oxide synthase inhibition exacerbates renal dysfunction in cirrhotic rats. Am J Physiol Renal Physiol. 2004;286:F288-F297.
-
(2004)
Am J Physiol Renal Physiol
, vol.286
, pp. F288-F297
-
-
Graebe, M.1
Brond, L.2
Christensen, S.3
Nielsen, S.4
Olsen, N.V.5
Jonassen, T.E.6
-
179
-
-
84915809448
-
Amiloride lowers blood pressure and attenuates urine plasminogen activation in patients with treatment-resistant hypertension
-
Oxlund CS, Buhl KB, Jacobsen IA, et al. Amiloride lowers blood pressure and attenuates urine plasminogen activation in patients with treatment-resistant hypertension. J Am Soc Hypertens. 2014;8:872-881.
-
(2014)
J Am Soc Hypertens
, vol.8
, pp. 872-881
-
-
Oxlund, C.S.1
Buhl, K.B.2
Jacobsen, I.A.3
-
180
-
-
34047268344
-
Low-dose aldosterone blockade as a new treatment paradigm for controlling resistant hypertension
-
Calhoun DA. Low-dose aldosterone blockade as a new treatment paradigm for controlling resistant hypertension. J Clin Hypertens (Greenwich). 2007;9(suppl 1):19-24.
-
(2007)
J Clin Hypertens (Greenwich)
, vol.9
, pp. 19-24
-
-
Calhoun, D.A.1
-
181
-
-
84969801219
-
Significant natriuretic and antihypertensive action of the epithelial sodium channel blocker amiloride in diabetic patients with and without nephropathy
-
Andersen H, Hansen PB, Bistrup C, Nielsen F, Henriksen JE, Jensen BL. Significant natriuretic and antihypertensive action of the epithelial sodium channel blocker amiloride in diabetic patients with and without nephropathy. J Hypertens. 2016;34:1621-1629.
-
(2016)
J Hypertens
, vol.34
, pp. 1621-1629
-
-
Andersen, H.1
Hansen, P.B.2
Bistrup, C.3
Nielsen, F.4
Henriksen, J.E.5
Jensen, B.L.6
-
182
-
-
0014381551
-
On the biochemical mechanism of action of aldosterone
-
Edelman IS, Fimognari GM. On the biochemical mechanism of action of aldosterone. Recent Prog Horm Res. 1968;24:1-44.
-
(1968)
Recent Prog Horm Res
, vol.24
, pp. 1-44
-
-
Edelman, I.S.1
Fimognari, G.M.2
-
183
-
-
0021019634
-
Short-term effects of aldosterone and dexamethasone on Na-K-ATPase along the rabbit nephron
-
El Mernissi G, Doucet A. Short-term effects of aldosterone and dexamethasone on Na-K-ATPase along the rabbit nephron. Pflugers Arch. 1983;399:147-151.
-
(1983)
Pflugers Arch
, vol.399
, pp. 147-151
-
-
El Mernissi, G.1
Doucet, A.2
-
184
-
-
68049088827
-
K+ secretion in the rat kidney: Na+ channel-dependent and -independent mechanisms
-
Frindt G, Palmer LG. K+ secretion in the rat kidney: Na+ channel-dependent and -independent mechanisms. Am J Physiol Renal Physiol. 2009;297:F389-F396.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F389-F396
-
-
Frindt, G.1
Palmer, L.G.2
-
185
-
-
0028879781
-
Regulatory volume decrease in a renal distal tubular cell line (A6). I. Role of K+ and Cl-aaaaaaaa
-
De Smet P, Simaels J, Van Driessche W. Regulatory volume decrease in a renal distal tubular cell line (A6). I. Role of K+ and Cl-aaaaaaaa. Pflugers Arch. 1995;430:936-944.
-
(1995)
Pflugers Arch
, vol.430
, pp. 936-944
-
-
De Smet, P.1
Simaels, J.2
Van Driessche, W.3
-
186
-
-
84918822606
-
Combination therapy with spironolactone and candesartan protects against streptozotocin-induced diabetic nephropathy in rats
-
Hofni A, El-Moselhy MA, Taye A, Khalifa MM. Combination therapy with spironolactone and candesartan protects against streptozotocin-induced diabetic nephropathy in rats. Eur J Pharmacol. 2014;744:173-182.
-
(2014)
Eur J Pharmacol
, vol.744
, pp. 173-182
-
-
Hofni, A.1
El-Moselhy, M.A.2
Taye, A.3
Khalifa, M.M.4
-
187
-
-
77955100072
-
Effect of ramipril alone compared to ramipril with eplerenone on diabetic nephropathy in streptozocin-induced diabetic rats
-
Mavrakanas TA, Cheva A, Kallaras K, Karkavelas G, Mironidou-Tzouveleki M. Effect of ramipril alone compared to ramipril with eplerenone on diabetic nephropathy in streptozocin-induced diabetic rats. Pharmacology. 2010;86:85-91.
-
(2010)
Pharmacology
, vol.86
, pp. 85-91
-
-
Mavrakanas, T.A.1
Cheva, A.2
Kallaras, K.3
Karkavelas, G.4
Mironidou-Tzouveleki, M.5
-
188
-
-
84860531024
-
Long-term mineralocorticoid receptor blockade ameliorates progression of experimental diabetic renal disease
-
Lian M, Hewitson TD, Wigg B, Samuel CS, Chow F, Becker GJ. Long-term mineralocorticoid receptor blockade ameliorates progression of experimental diabetic renal disease. Nephrol Dial Transplant. 2012;27:906-912.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 906-912
-
-
Lian, M.1
Hewitson, T.D.2
Wigg, B.3
Samuel, C.S.4
Chow, F.5
Becker, G.J.6
-
189
-
-
36349013809
-
Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats
-
Yuan J, Jia R, Bao Y. Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats. J Renin Angiotensin Aldosterone Syst. 2007;8:118-126.
-
(2007)
J Renin Angiotensin Aldosterone Syst
, vol.8
, pp. 118-126
-
-
Yuan, J.1
Jia, R.2
Bao, Y.3
-
190
-
-
47549114629
-
Spironolactone exhibits direct renoprotective effects and inhibits renal renin-angiotensin-aldosterone system in diabetic rats
-
Taira M, Toba H, Murakami M, et al. Spironolactone exhibits direct renoprotective effects and inhibits renal renin-angiotensin-aldosterone system in diabetic rats. Eur J Pharmacol. 2008;589:264-271.
-
(2008)
Eur J Pharmacol
, vol.589
, pp. 264-271
-
-
Taira, M.1
Toba, H.2
Murakami, M.3
-
191
-
-
58049209809
-
Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats
-
Kang YS, Ko GJ, Lee MH, et al. Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats. Nephrol Dial Transplant. 2009;24:73-84.
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 73-84
-
-
Kang, Y.S.1
Ko, G.J.2
Lee, M.H.3
-
192
-
-
23144443886
-
Human renal mesangial cells produce aldosterone in response to low-density lipoprotein (LDL)
-
Nishikawa T, Suematsu S, Saito J, et al. Human renal mesangial cells produce aldosterone in response to low-density lipoprotein (LDL). J Steroid Biochem Mol Biol. 2005;96:309-316.
-
(2005)
J Steroid Biochem Mol Biol
, vol.96
, pp. 309-316
-
-
Nishikawa, T.1
Suematsu, S.2
Saito, J.3
-
193
-
-
84894106381
-
Mineralocorticoid receptor blockade in addition to angiotensin converting enzyme inhibitor or angiotensin II receptor blocker treatment: an emerging paradigm in diabetic nephropathy: a systematic review
-
Mavrakanas TA, Gariani K, Martin PY. Mineralocorticoid receptor blockade in addition to angiotensin converting enzyme inhibitor or angiotensin II receptor blocker treatment: an emerging paradigm in diabetic nephropathy: a systematic review. Eur J Intern Med. 2014;25:173-116.
-
(2014)
Eur J Intern Med
, vol.25
, pp. 116-173
-
-
Mavrakanas, T.A.1
Gariani, K.2
Martin, P.Y.3
-
194
-
-
57049133582
-
The effects of spironolactone on nephron function in patients with diabetic nephropathy
-
Ustundag A, Tugrul A, Ustundag S, Sut N, Demirkan B. The effects of spironolactone on nephron function in patients with diabetic nephropathy. Ren Fail. 2008;30:982-991.
-
(2008)
Ren Fail
, vol.30
, pp. 982-991
-
-
Ustundag, A.1
Tugrul, A.2
Ustundag, S.3
Sut, N.4
Demirkan, B.5
-
195
-
-
33746566456
-
Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy
-
Schjoedt KJ, Rossing K, Juhl TR, et al. Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy. Kidney Int. 2006;70:536-542.
-
(2006)
Kidney Int
, vol.70
, pp. 536-542
-
-
Schjoedt, K.J.1
Rossing, K.2
Juhl, T.R.3
-
196
-
-
39949083037
-
Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells
-
Pinto V, Pinho MJ, Hopfer U, Jose PA, Soares-da-Silva P. Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells. Mol Cell Biochem. 2008;310:191-201.
-
(2008)
Mol Cell Biochem
, vol.310
, pp. 191-201
-
-
Pinto, V.1
Pinho, M.J.2
Hopfer, U.3
Jose, P.A.4
Soares-da-Silva, P.5
-
197
-
-
70350641930
-
The role of Na+-H+ exchanger isoform 1 in aldosterone-induced glomerulosclerosis in vivo
-
Zhang M, Chen J, Liu S, You L, Lin S, Gu Y. The role of Na+-H+ exchanger isoform 1 in aldosterone-induced glomerulosclerosis in vivo. Ren Fail. 2009;31:726-735.
-
(2009)
Ren Fail
, vol.31
, pp. 726-735
-
-
Zhang, M.1
Chen, J.2
Liu, S.3
You, L.4
Lin, S.5
Gu, Y.6
-
198
-
-
33644996927
-
Aldosterone stimulates activity and surface expression of NHE3 in human primary proximal tubule epithelial cells (RPTEC)
-
Drumm K, Kress TR, Gassner B, Krug AW, Gekle M. Aldosterone stimulates activity and surface expression of NHE3 in human primary proximal tubule epithelial cells (RPTEC). Cell Physiol Biochem. 2006;17:21-28.
-
(2006)
Cell Physiol Biochem
, vol.17
, pp. 21-28
-
-
Drumm, K.1
Kress, T.R.2
Gassner, B.3
Krug, A.W.4
Gekle, M.5
-
199
-
-
70350695788
-
Aldosterone promotes fibronectin synthesis in rat mesangial cells via ERK1/2-stimulated Na-H+ exchanger isoform 1
-
Zhang M, Chen J, Lai L, et al. Aldosterone promotes fibronectin synthesis in rat mesangial cells via ERK1/2-stimulated Na-H+ exchanger isoform 1. Am J Nephrol. 2010;31:75-82.
-
(2010)
Am J Nephrol
, vol.31
, pp. 75-82
-
-
Zhang, M.1
Chen, J.2
Lai, L.3
-
200
-
-
0041665018
-
Aldosterone stimulates surface expression of NHE3 in renal proximal brush borders
-
Krug AW, Papavassiliou F, Hopfer U, Ullrich KJ, Gekle M. Aldosterone stimulates surface expression of NHE3 in renal proximal brush borders. Pflugers Arch. 2003;446:492-496.
-
(2003)
Pflugers Arch
, vol.446
, pp. 492-496
-
-
Krug, A.W.1
Papavassiliou, F.2
Hopfer, U.3
Ullrich, K.J.4
Gekle, M.5
-
201
-
-
2642647084
-
Chronic hyperosmolality increases NHE3 activity in OKP cells
-
Ambühl P, Amemiya M, Preisig PA, Moe OW, Alpern RJ. Chronic hyperosmolality increases NHE3 activity in OKP cells. J Clin Invest. 1998;101:170-177.
-
(1998)
J Clin Invest
, vol.101
, pp. 170-177
-
-
Ambühl, P.1
Amemiya, M.2
Preisig, P.A.3
Moe, O.W.4
Alpern, R.J.5
-
202
-
-
84943609141
-
Spironolactone inhibits podocyte motility via decreasing integrin β1 and increasing integrin β3 in podocytes under high-glucose conditions
-
Li Z, Zhang L, Shi W, et al. Spironolactone inhibits podocyte motility via decreasing integrin β1 and increasing integrin β3 in podocytes under high-glucose conditions. Mol Med Rep. 2015;12:6849-6854.
-
(2015)
Mol Med Rep
, vol.12
, pp. 6849-6854
-
-
Li, Z.1
Zhang, L.2
Shi, W.3
-
203
-
-
79961096910
-
Spironolactone inhibits hyperglycemia-induced podocyte injury by attenuating ROS production
-
Toyonaga J, Tsuruya K, Ikeda H, et al. Spironolactone inhibits hyperglycemia-induced podocyte injury by attenuating ROS production. Nephrol Dial Transplant. 2011;26:2475-2484.
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 2475-2484
-
-
Toyonaga, J.1
Tsuruya, K.2
Ikeda, H.3
-
204
-
-
77249109990
-
Mineralocorticoid receptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats
-
Nishiyama A, Kobori H, Konishi Y, et al. Mineralocorticoid receptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats. J Pharmacol Exp Ther. 2010;332:1072-1080.
-
(2010)
J Pharmacol Exp Ther
, vol.332
, pp. 1072-1080
-
-
Nishiyama, A.1
Kobori, H.2
Konishi, Y.3
-
205
-
-
70350710165
-
Activation of local aldosterone system within podocytes is involved in apoptosis under diabetic conditions
-
Lee SH, Yoo TH, Nam BY, et al. Activation of local aldosterone system within podocytes is involved in apoptosis under diabetic conditions. Am J Physiol Renal Physiol. 2009;297:F1381-F1390.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F1381-F1390
-
-
Lee, S.H.1
Yoo, T.H.2
Nam, B.Y.3
-
206
-
-
84880842887
-
+ exchanger type 1 and intracellular pH in angiotensin II-induced reactive oxygen species generation and podocyte apoptosis
-
+ exchanger type 1 and intracellular pH in angiotensin II-induced reactive oxygen species generation and podocyte apoptosis. J Pharmacol Sci. 2013;122:176-183.
-
(2013)
J Pharmacol Sci
, vol.122
, pp. 176-183
-
-
Liu, Y.1
Hitomi, H.2
Diah, S.3
-
207
-
-
0141457720
-
Mutations in the epithelial Na+ channel ENaC outer pore disrupt amiloride block by increasing its dissociation rate
-
Kellenberger S, Gautschi I, Schild L. Mutations in the epithelial Na+ channel ENaC outer pore disrupt amiloride block by increasing its dissociation rate. Mol Pharmacol. 2003;64:848-856.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 848-856
-
-
Kellenberger, S.1
Gautschi, I.2
Schild, L.3
-
208
-
-
38049033935
-
Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis
-
Kearney PM, Blackwell L, Collins R, et al. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet. 2008;371:117-125.
-
(2008)
Lancet
, vol.371
, pp. 117-125
-
-
Kearney, P.M.1
Blackwell, L.2
Collins, R.3
-
209
-
-
4344683381
-
Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial
-
Colhoun HM, Betteridge DJ, Durrington PN, et al. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet. 2004;364:685-696.
-
(2004)
Lancet
, vol.364
, pp. 685-696
-
-
Colhoun, H.M.1
Betteridge, D.J.2
Durrington, P.N.3
-
210
-
-
33748303084
-
Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: analysis of the Treating to New Targets study
-
Deedwania P, Barter P, Carmena R, et al. Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: analysis of the Treating to New Targets study. Lancet. 2006;368:919-928.
-
(2006)
Lancet
, vol.368
, pp. 919-928
-
-
Deedwania, P.1
Barter, P.2
Carmena, R.3
-
211
-
-
84906101827
-
Meta-analysis of the effect of statins on renal function
-
Geng Q, Ren J, Song J, Li S, Chen H. Meta-analysis of the effect of statins on renal function. Am J Cardiol. 2014;114:562-570.
-
(2014)
Am J Cardiol
, vol.114
, pp. 562-570
-
-
Geng, Q.1
Ren, J.2
Song, J.3
Li, S.4
Chen, H.5
-
212
-
-
84887210473
-
A meta-analysis of the role of statins on renal outcomes in patients with chronic kidney disease. Is the duration of therapy important?
-
Nikolic D, Banach M, Nikfar S, et al. A meta-analysis of the role of statins on renal outcomes in patients with chronic kidney disease. Is the duration of therapy important? Int J Cardiol. 2013;168:5437-5447.
-
(2013)
Int J Cardiol
, vol.168
, pp. 5437-5447
-
-
Nikolic, D.1
Banach, M.2
Nikfar, S.3
-
213
-
-
38349045501
-
Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt signaling pathway
-
Lin CL, Cheng H, Tung CW, et al. Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt signaling pathway. Am J Nephrol. 2008;28:290-297.
-
(2008)
Am J Nephrol
, vol.28
, pp. 290-297
-
-
Lin, C.L.1
Cheng, H.2
Tung, C.W.3
-
214
-
-
23844454204
-
Effects of simvastatin on oxidative stress in streptozotocin-induced diabetic rats: a role for glomeruli protection
-
Zhu B, Shen H, Zhou J, Lin F, Hu Y. Effects of simvastatin on oxidative stress in streptozotocin-induced diabetic rats: a role for glomeruli protection. Nephron Exp Nephrol. 2005;101:e1-e8.
-
(2005)
Nephron Exp Nephrol
, vol.101
, pp. e1-e8
-
-
Zhu, B.1
Shen, H.2
Zhou, J.3
Lin, F.4
Hu, Y.5
-
215
-
-
17044385829
-
Potential role of angiotensin-converting enzyme inhibitors and statins on early podocyte damage in a model of type 2 diabetes mellitus, obesity, and mild hypertension
-
Blanco S, Vaquero M, Gómez-Guerrero C, López D, Egido J, Romero R. Potential role of angiotensin-converting enzyme inhibitors and statins on early podocyte damage in a model of type 2 diabetes mellitus, obesity, and mild hypertension. Am J Hypertens. 2005;18(4, pt 1):557-565.
-
(2005)
Am J Hypertens
, vol.18
, pp. 557-565
-
-
Blanco, S.1
Vaquero, M.2
Gómez-Guerrero, C.3
López, D.4
Egido, J.5
Romero, R.6
-
216
-
-
0038119554
-
Effects of the combination of an angiotensin II antagonist with an HMG-CoA reductase inhibitor in experimental diabetes
-
Qin J, Zhang Z, Liu J, et al. Effects of the combination of an angiotensin II antagonist with an HMG-CoA reductase inhibitor in experimental diabetes. Kidney Int. 2003;64:565-571.
-
(2003)
Kidney Int
, vol.64
, pp. 565-571
-
-
Qin, J.1
Zhang, Z.2
Liu, J.3
-
217
-
-
78349285889
-
Adding a statin to a combination of ACE inhibitor and ARB normalizes proteinuria in experimental diabetes, which translates into full renoprotection
-
Zoja C, Corna D, Gagliardini E, et al. Adding a statin to a combination of ACE inhibitor and ARB normalizes proteinuria in experimental diabetes, which translates into full renoprotection. Am J Physiol Renal Physiol. 2010;299:F1203-F1211.
-
(2010)
Am J Physiol Renal Physiol
, vol.299
, pp. F1203-F1211
-
-
Zoja, C.1
Corna, D.2
Gagliardini, E.3
-
218
-
-
84904272570
-
Renoprotective effect of atorvastatin on STZ-diabetic rats through attenuating kidney-associated dysmetabolism
-
Zhou S, Zhao P, Li Y, Deng T, Tian L, Li H. Renoprotective effect of atorvastatin on STZ-diabetic rats through attenuating kidney-associated dysmetabolism. Eur J Pharmacol. 2014;740:9-14.
-
(2014)
Eur J Pharmacol
, vol.740
, pp. 9-14
-
-
Zhou, S.1
Zhao, P.2
Li, Y.3
Deng, T.4
Tian, L.5
Li, H.6
-
219
-
-
84999143081
-
Greater efficacy of atorvastatin versus a non-statin lipid-lowering agent against renal injury: potential role as a histone de-acetylase inhibitor
-
38034
-
Singh RS, Chaudhary DK, Mohan A, et al. Greater efficacy of atorvastatin versus a non-statin lipid-lowering agent against renal injury: potential role as a histone de-acetylase inhibitor. Sci Rep. 2016;6:38034. https://doi.org/10.1038/srep38034.
-
(2016)
Sci Rep
, vol.6
-
-
Singh, R.S.1
Chaudhary, D.K.2
Mohan, A.3
-
220
-
-
77956493744
-
The pleiotropic actions of rosuvastatin confer renal benefits in the diabetic Apo-E knockout mouse
-
Giunti S, Calkin AC, Forbes JM, et al. The pleiotropic actions of rosuvastatin confer renal benefits in the diabetic Apo-E knockout mouse. Am J Physiol Renal Physiol. 2010;299:F528-F535.
-
(2010)
Am J Physiol Renal Physiol
, vol.299
, pp. F528-F535
-
-
Giunti, S.1
Calkin, A.C.2
Forbes, J.M.3
-
221
-
-
28044452217
-
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial
-
Keech A, Simes RJ, Barter P, et al. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet. 2005;366:1849-1861.
-
(2005)
Lancet
, vol.366
, pp. 1849-1861
-
-
Keech, A.1
Simes, R.J.2
Barter, P.3
-
222
-
-
80052048877
-
Prevention of microvascular diabetic complications by fenofibrate: lessons from FIELD and ACCORD
-
Hermans MP. Prevention of microvascular diabetic complications by fenofibrate: lessons from FIELD and ACCORD. Diab Vasc Dis Res. 2011;8:180-189.
-
(2011)
Diab Vasc Dis Res
, vol.8
, pp. 180-189
-
-
Hermans, M.P.1
-
223
-
-
84865413263
-
Fenofibrate-associated changes in renal function and relationship to clinical outcomes among individuals with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) experience
-
Bonds DE, Craven TE, Buse J, et al. Fenofibrate-associated changes in renal function and relationship to clinical outcomes among individuals with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) experience. Diabetologia. 2012;55:1641-1650.
-
(2012)
Diabetologia
, vol.55
, pp. 1641-1650
-
-
Bonds, D.E.1
Craven, T.E.2
Buse, J.3
-
224
-
-
77956744479
-
Effects of combined ezetimibe and simvastatin therapy as compared with simvastatin alone in patients with type 2 diabetes: a prospective randomized double-blind clinical trial
-
Ruggenenti P, Cattaneo D, Rota S, et al. Effects of combined ezetimibe and simvastatin therapy as compared with simvastatin alone in patients with type 2 diabetes: a prospective randomized double-blind clinical trial. Diabetes Care. 2010;33:1954-1956.
-
(2010)
Diabetes Care
, vol.33
, pp. 1954-1956
-
-
Ruggenenti, P.1
Cattaneo, D.2
Rota, S.3
-
225
-
-
0026590192
-
Lipids and cellular Na+/H+ antiport activity in diabetic nephropathy
-
Ng LL, Davies JE. Lipids and cellular Na+/H+ antiport activity in diabetic nephropathy. Kidney Int. 1992;41:872-876.
-
(1992)
Kidney Int
, vol.41
, pp. 872-876
-
-
Ng, L.L.1
Davies, J.E.2
-
226
-
-
0026342514
-
HMG CoA reductase inhibitors affect Na(+)-H+ antiport activity in human lymphoblasts
-
Ng LL, Davies JE. HMG CoA reductase inhibitors affect Na(+)-H+ antiport activity in human lymphoblasts. Am J Physiol. 1991;261:C780-C786.
-
(1991)
Am J Physiol
, vol.261
, pp. C780-C786
-
-
Ng, L.L.1
Davies, J.E.2
-
227
-
-
0027246443
-
Simvastatin and intracellular pH regulation by the Na+/H+ antiport of SV40-virus-transformed human MRC5 fibroblasts
-
Davies JE, Ng LL. Simvastatin and intracellular pH regulation by the Na+/H+ antiport of SV40-virus-transformed human MRC5 fibroblasts. Clin Sci (Lond). 1993;84:633-643.
-
(1993)
Clin Sci (Lond)
, vol.84
, pp. 633-643
-
-
Davies, J.E.1
Ng, L.L.2
-
228
-
-
0032895195
-
In vitro effects of simvastatin on tubulointerstitial cells in a human model of cyclosporin nephrotoxicity
-
Johnson DW, Saunders HJ, Field MJ, Pollock CA. In vitro effects of simvastatin on tubulointerstitial cells in a human model of cyclosporin nephrotoxicity. Am J Physiol. 1999;276:F467-F475.
-
(1999)
Am J Physiol
, vol.276
, pp. F467-F475
-
-
Johnson, D.W.1
Saunders, H.J.2
Field, M.J.3
Pollock, C.A.4
-
229
-
-
0031611941
-
Effects of lipid-lowering agents in the Dahl salt-sensitive rat
-
Wilson TW, Alonso-Galicia M, Roman RJ. Effects of lipid-lowering agents in the Dahl salt-sensitive rat. Hypertension. 1998;31:225-231.
-
(1998)
Hypertension
, vol.31
, pp. 225-231
-
-
Wilson, T.W.1
Alonso-Galicia, M.2
Roman, R.J.3
-
230
-
-
84864516351
-
Atorvastatin improves sodium handling and decreases blood pressure in salt-loaded rats with chronic renal insufficiency
-
Juncos LI, Martín FL, Baigorria ST, et al. Atorvastatin improves sodium handling and decreases blood pressure in salt-loaded rats with chronic renal insufficiency. Nutrition. 2012;28:e23-e28.
-
(2012)
Nutrition
, vol.28
, pp. e23-e28
-
-
Juncos, L.I.1
Martín, F.L.2
Baigorria, S.T.3
-
231
-
-
77953802869
-
Acute effects of atorvastatin on glomerular filtration rate, tubular function, blood pressure, and vasoactive hormones in patients with type 2 diabetes
-
Paulsen L, Matthesen SK, Bech JN, Starklint J, Pedersen EB. Acute effects of atorvastatin on glomerular filtration rate, tubular function, blood pressure, and vasoactive hormones in patients with type 2 diabetes. J Clin Pharmacol. 2010;50:816-822.
-
(2010)
J Clin Pharmacol
, vol.50
, pp. 816-822
-
-
Paulsen, L.1
Matthesen, S.K.2
Bech, J.N.3
Starklint, J.4
Pedersen, E.B.5
-
232
-
-
44449123556
-
Effects of statins on renal sodium and water handling: acute and short-term effects of atorvastatin on renal haemodynamics, tubular function, vasoactive hormones, blood pressure and pulse rate in healthy, normocholesterolemic humans
-
Paulsen L, Holm C, Bech JN, Starklint J, Pedersen EB. Effects of statins on renal sodium and water handling: acute and short-term effects of atorvastatin on renal haemodynamics, tubular function, vasoactive hormones, blood pressure and pulse rate in healthy, normocholesterolemic humans. Nephrol Dial Transplant. 2008;23:1556-1561.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 1556-1561
-
-
Paulsen, L.1
Holm, C.2
Bech, J.N.3
Starklint, J.4
Pedersen, E.B.5
-
234
-
-
0042856663
-
Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarc-tion in high-risk CABG surgery patients: results of the CABG surgery cohort of the GUARDIAN study
-
Boyce SW, Bartels C, Bolli R, et al. Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarc-tion in high-risk CABG surgery patients: results of the CABG surgery cohort of the GUARDIAN study. J Thorac Cardiovasc Surg. 2003;126:420-427.
-
(2003)
J Thorac Cardiovasc Surg
, vol.126
, pp. 420-427
-
-
Boyce, S.W.1
Bartels, C.2
Bolli, R.3
-
235
-
-
85008253144
-
Na(+)/H(+) exchanger in the regulation of platelet activation and paradoxical effects of cariporide
-
Chang HB, Gao X, Nepomuceno R, Hu S, Sun D. Na(+)/H(+) exchanger in the regulation of platelet activation and paradoxical effects of cariporide. Exp Neurol. 2015;272:11-16.
-
(2015)
Exp Neurol
, vol.272
, pp. 11-16
-
-
Chang, H.B.1
Gao, X.2
Nepomuceno, R.3
Hu, S.4
Sun, D.5
-
236
-
-
0038851888
-
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger
-
Schultheis PJ, Clarke LL, Meneton P, et al. Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Nat Genet. 1998;19:282-285.
-
(1998)
Nat Genet
, vol.19
, pp. 282-285
-
-
Schultheis, P.J.1
Clarke, L.L.2
Meneton, P.3
-
237
-
-
85037646035
-
NHE3 blockade ameliorates type 2 diabetes mellitus via inhibition of SGLT1-mediated glucose absorption in the small intestine
-
Chan LKY, Wang Y, Ng EKW, Leung PS. NHE3 blockade ameliorates type 2 diabetes mellitus via inhibition of SGLT1-mediated glucose absorption in the small intestine. Diabetes Obes Metab. 2018;20:709-717.
-
(2018)
Diabetes Obes Metab
, vol.20
, pp. 709-717
-
-
Chan, L.K.Y.1
Wang, Y.2
Ng, E.K.W.3
Leung, P.S.4
-
238
-
-
84870244323
-
Antihypertensive and laxative effects by pharmacological inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut
-
Linz D, Wirth K, Linz W, et al. Antihypertensive and laxative effects by pharmacological inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut. Hypertension. 2012;60:1560-1567.
-
(2012)
Hypertension
, vol.60
, pp. 1560-1567
-
-
Linz, D.1
Wirth, K.2
Linz, W.3
-
239
-
-
84881258047
-
+ exchanger NHE3: effects on bicarbonate absorption and ammonium excretion
-
+ exchanger NHE3: effects on bicarbonate absorption and ammonium excretion. J Mol Med (Berl). 2013;91:951-963.
-
(2013)
J Mol Med (Berl)
, vol.91
, pp. 951-963
-
-
Li, H.C.1
Du, Z.2
Barone, S.3
-
240
-
-
84931096369
-
Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3
-
Fenton RA, Poulsen SB, de la Mora Chavez S, et al. Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3. Am J Physiol Renal Physiol. 2015;308:F1409-F1420.
-
(2015)
Am J Physiol Renal Physiol
, vol.308
, pp. F1409-F1420
-
-
Fenton, R.A.1
Poulsen, S.B.2
de la Mora Chavez, S.3
-
241
-
-
85014362087
-
Targeting gene expression to specific cells of kidney tubules in vivo, using adenoviral promoter fragments
-
Watanabe S, Ogasawara T, Tamura Y, et al. Targeting gene expression to specific cells of kidney tubules in vivo, using adenoviral promoter fragments. PLoS One. 2017;12(3):e0168638. https://doi.org/10.1371/journal.pone.0168638.
-
(2017)
PLoS One
, vol.12
, Issue.3
-
-
Watanabe, S.1
Ogasawara, T.2
Tamura, Y.3
-
242
-
-
84921683215
-
Cyclic GMP kinase II (cGKII) inhibits NHE3 by altering its trafficking and phosphorylating NHE3 at three required sites: identification of a multifunctional phosphorylation site
-
Chen T, Kocinsky HS, Cha B, et al. Cyclic GMP kinase II (cGKII) inhibits NHE3 by altering its trafficking and phosphorylating NHE3 at three required sites: identification of a multifunctional phosphorylation site. J Biol Chem. 2015;290:1952-1965.
-
(2015)
J Biol Chem
, vol.290
, pp. 1952-1965
-
-
Chen, T.1
Kocinsky, H.S.2
Cha, B.3
-
243
-
-
85021666674
-
Phosphorylation of NHE3-S719 regulates NHE3 activity through the formation of multiple signaling complexes
-
Sarker R, Cha B, Kovbasnjuk O, et al. Phosphorylation of NHE3-S719 regulates NHE3 activity through the formation of multiple signaling complexes. Mol Biol Cell. 2017;28:1754-1767.
-
(2017)
Mol Biol Cell
, vol.28
, pp. 1754-1767
-
-
Sarker, R.1
Cha, B.2
Kovbasnjuk, O.3
-
244
-
-
84984605072
-
The NHERF1 PDZ1 domain and IRBIT interact and mediate the activation of Na+/H+ exchanger 3 by ANG II
-
He P, Zhao L, No YR, Karvar S, Yun CC. The NHERF1 PDZ1 domain and IRBIT interact and mediate the activation of Na+/H+ exchanger 3 by ANG II. Am J Physiol Renal Physiol. 2016;311:F343-F351.
-
(2016)
Am J Physiol Renal Physiol
, vol.311
, pp. F343-F351
-
-
He, P.1
Zhao, L.2
No, Y.R.3
Karvar, S.4
Yun, C.C.5
-
245
-
-
84934903928
-
The Na+/H+ exchanger-3 (NHE3) activity requires ezrin binding to phosphoinositide and its phosphorylation
-
Babich V, Di Sole F. The Na+/H+ exchanger-3 (NHE3) activity requires ezrin binding to phosphoinositide and its phosphorylation. PLoS One. 2015;10:e0129306.
-
(2015)
PLoS One
, vol.10
-
-
Babich, V.1
Di Sole, F.2
-
246
-
-
84930386121
-
Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3
-
Singh V, Yang J, Cha B, et al. Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3. Mol Biol Cell. 2015;26:2030-2043.
-
(2015)
Mol Biol Cell
, vol.26
, pp. 2030-2043
-
-
Singh, V.1
Yang, J.2
Cha, B.3
|