Mutations in the epithelial Na+ channel ENaC outer pore disrupt amiloride block by increasing its dissociation rate

Molecular Pharmacology

Volumn 64, Issue 4, 2003, Pages 848-856

  Kellenberger, Stephan ^a   Gautschi, Ivan ^a   Schild, Laurent ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; BENZAMIL; POTASSIUM SPARING DIURETIC AGENT; SODIUM CHANNEL;

APICAL MEMBRANE; ARTICLE; BINDING SITE; DISSOCIATION CONSTANT; EPITHELIUM CELL; GENE MUTATION; MUTAGENESIS; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; RECEPTOR BINDING; SALT LOSING NEPHRITIS; SODIUM ABSORPTION; SODIUM BALANCE; SODIUM EXCRETION;

AMILORIDE; ANIMALS; ELECTROPHYSIOLOGY; EPITHELIAL SODIUM CHANNEL; KINETICS; MUTAGENESIS, SITE-DIRECTED; OOCYTES; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TRANSFECTION; XENOPUS LAEVIS;

EID: 0141457720     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.4.848     Document Type: Article

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