메뉴 건너뛰기




Volumn 12, Issue , 2016, Pages 393-405

Impact of sodium–glucose cotransporter 2 inhibitors on blood pressure

Author keywords

Blood pressure; Canagliflozin; Dapagliflozin; Empagliflozin; Sodium glucose cotransporter 2 inhibitors; Type 2 diabetes

Indexed keywords

CANAGLIFLOZIN; DAPAGLIFLOZIN; EMPAGLIFLOZIN; HYDROCHLOROTHIAZIDE; PLACEBO; 2-(3-(4-ETHOXYBENZYL)-4-CHLOROPHENYL)-6-HYDROXYMETHYLTETRAHYDRO-2H-PYRAN-3,4,5-TRIOL; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; BENZHYDRYL DERIVATIVE; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; GLUCOSIDE; SLC5A2 PROTEIN, HUMAN; SODIUM GLUCOSE COTRANSPORTER 2;

EID: 84994476908     PISSN: 11766344     EISSN: 11782048     Source Type: Journal    
DOI: 10.2147/VHRM.S111991     Document Type: Review
Times cited : (55)

References (100)
  • 1
    • 84884547666 scopus 로고    scopus 로고
    • Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: A systematic literature review
    • Colosia AD, Palencia R, Khan S. Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review. Diabetes Metab Syndr Obes. 2013;6:327-338.
    • (2013) Diabetes Metab Syndr Obes , vol.6 , pp. 327-338
    • Colosia, A.D.1    Palencia, R.2    Khan, S.3
  • 2
    • 84994436514 scopus 로고    scopus 로고
    • National Diabetes Statistics Report, 2014. Atlanta: CDC
    • Centers for Disease Control and Prevention. National Diabetes Statistics Report, 2014. Atlanta: CDC; 2014.
    • (2014)
  • 3
    • 85020346886 scopus 로고    scopus 로고
    • Clinical characteristics, complications, comorbidities and treatment patterns among patients with type 2 diabetes mellitus in a large integrated health system
    • Pantalone KM, Hobbs TM, Wells BJ, et al. Clinical characteristics, complications, comorbidities and treatment patterns among patients with type 2 diabetes mellitus in a large integrated health system. BMJ Open Diabetes Res Care. 2015;3(1):e000093.
    • (2015) BMJ Open Diabetes Res Care , vol.3 , Issue.1
    • Pantalone, K.M.1    Hobbs, T.M.2    Wells, B.J.3
  • 4
    • 84901808693 scopus 로고    scopus 로고
    • Blood pressure and incidence of twelve cardiovascular diseases: Lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people
    • Rapsomaniki E, Timmis A, George J, et al. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people. Lancet. 2014;383(9932):1899-1911.
    • (2014) Lancet , vol.383 , Issue.9932 , pp. 1899-1911
    • Rapsomaniki, E.1    Timmis, A.2    George, J.3
  • 5
    • 84958584867 scopus 로고    scopus 로고
    • Cardiovascular disease and risk management
    • American Diabetes Association. Cardiovascular disease and risk management. Diabetes Care. 2016;39(Suppl 1):S60-S71.
    • (2016) Diabetes Care , vol.39 , pp. S60-S71
  • 6
    • 84901467782 scopus 로고    scopus 로고
    • Importance of cardiovascular disease risk management in patients with type 2 diabetes mellitus
    • Lorber D. Importance of cardiovascular disease risk management in patients with type 2 diabetes mellitus. Diabetes Metab Syndr Obes. 2014;7:169-183.
    • (2014) Diabetes Metab Syndr Obes , vol.7 , pp. 169-183
    • Lorber, D.1
  • 8
    • 0032511580 scopus 로고    scopus 로고
    • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38
    • UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ. 1998;317(7160):703-713.
    • (1998) BMJ , vol.317 , Issue.7160 , pp. 703-713
  • 9
    • 0034641550 scopus 로고    scopus 로고
    • Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): Prospective observational study
    • Adler AI, Stratton IM, Neil HA, et al. Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study. BMJ. 2000;321(7258):412-419.
    • (2000) BMJ , vol.321 , Issue.7258 , pp. 412-419
    • Adler, A.I.1    Stratton, I.M.2    Neil, H.A.3
  • 10
    • 84922567942 scopus 로고    scopus 로고
    • Blood pressure lowering in type 2 diabetes: A systematic review and metaanalysis
    • Emdin CA, Rahimi K, Neal B, Callender T, Perkovic V, Patel A. Blood pressure lowering in type 2 diabetes: a systematic review and metaanalysis. JAMA. 2015;313(6):603-615.
    • (2015) JAMA , vol.313 , Issue.6 , pp. 603-615
    • Emdin, C.A.1    Rahimi, K.2    Neal, B.3    Callender, T.4    Perkovic, V.5    Patel, A.6
  • 11
    • 84885997413 scopus 로고    scopus 로고
    • ESC guidelines on diabetes, prediabetes, and cardiovascular diseases developed in collaboration with the EASD
    • Rydén L, Grant PJ, Anker SD, et al. ESC guidelines on diabetes, prediabetes, and cardiovascular diseases developed in collaboration with the EASD. Eur Heart J. 2013;34(39):3035-3087.
    • (2013) Eur Heart J , vol.34 , Issue.39 , pp. 3035-3087
    • Rydén, L.1    Grant, P.J.2    Anker, S.D.3
  • 12
    • 84892367290 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of hypertension in the community: A statement by the American Society of Hypertension and the International Society of Hypertension
    • Weber MA, Schiffrin EL, White WB, et al. Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. J Clin Hypertens (Greenwich). 2014;16(1):14-26.
    • (2014) J Clin Hypertens (Greenwich) , vol.16 , Issue.1 , pp. 14-26
    • Weber, M.A.1    Schiffrin, E.L.2    White, W.B.3
  • 13
    • 84897076285 scopus 로고    scopus 로고
    • An effective approach to high blood pressure control: A science advisory from the American Heart Association, the American College of Cardiology, and the Centers for Disease Control and Prevention
    • Go AS, Bauman MA, King SM, et al. An effective approach to high blood pressure control: a science advisory from the American Heart Association, the American College of Cardiology, and the Centers for Disease Control and Prevention. Hypertension. 2014;63(4):878-885.
    • (2014) Hypertension , vol.63 , Issue.4 , pp. 878-885
    • Go, A.S.1    Bauman, M.A.2    King, S.M.3
  • 14
    • 84893549987 scopus 로고    scopus 로고
    • Evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8)
    • James PA, Oparil S, Carter BL, et al. 2014 Evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311(5):507-520.
    • (2014) JAMA , vol.311 , Issue.5 , pp. 507-520
    • James, P.A.1    Oparil, S.2    Carter, B.L.3
  • 15
    • 84899468978 scopus 로고    scopus 로고
    • Blood pressure targets for hypertension in people with diabetes mellitus
    • CD008277
    • Arguedas JA, Leiva V, Wright JM. Blood pressure targets for hypertension in people with diabetes mellitus. Cochrane Database Syst Rev. 2013;(10):CD008277.
    • (2013) Cochrane Database Syst Rev , Issue.10
    • Arguedas, J.A.1    Leiva, V.2    Wright, J.M.3
  • 16
    • 84930841315 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists and American College of Endocrinology: Clinical practice guidelines for developing a diabetes mellitus comprehensive care plan-2015
    • Handelsman Y, Bloomgarden ZT, Grunberger G, et al. American Association of Clinical Endocrinologists and American College of Endocrinology: clinical practice guidelines for developing a diabetes mellitus comprehensive care plan-2015. Endocr Pract. 2015;21 Suppl 1:1-87.
    • Endocr Pract. 2015;21 Suppl , vol.1 , pp. 1-87
    • Handelsman, Y.1    Bloomgarden, Z.T.2    Grunberger, G.3
  • 17
    • 84928821188 scopus 로고    scopus 로고
    • The 2015 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension
    • Daskalopoulou SS, Rabi DM, Zarnke KB, et al. The 2015 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. Can J Cardiol. 2015;31(5):549-568.
    • (2015) Can J Cardiol , vol.31 , Issue.5 , pp. 549-568
    • Daskalopoulou, S.S.1    Rabi, D.M.2    Zarnke, K.B.3
  • 18
    • 84982074515 scopus 로고    scopus 로고
    • Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm: 2016 executive summary
    • Garber AJ, Abrahamson MJ, Barzilay JI, et al. Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm: 2016 executive summary. Endocr Pract. 2016;22(1): 84-113.
    • (2016) Endocr Pract , vol.22 , Issue.1 , pp. 84-113
    • Garber, A.J.1    Abrahamson, M.J.2    Barzilay, J.I.3
  • 19
    • 84929414367 scopus 로고    scopus 로고
    • Blood pressure targets in patients with diabetes: A new perspective
    • Rosendorff C. Blood pressure targets in patients with diabetes: a new perspective. J Am Soc Hypertens. 2015;9(5):334-336.
    • (2015) J am Soc Hypertens , vol.9 , Issue.5 , pp. 334-336
    • Rosendorff, C.1
  • 20
    • 84959363424 scopus 로고    scopus 로고
    • Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: Updated systematic review and meta-analysis
    • Xie X, Atkins E, Lv J, et al. Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis. Lancet. 2016;387(10017):435-443.
    • (2016) Lancet , vol.387 , Issue.10017 , pp. 435-443
    • Xie, X.1    Atkins, E.2    Lv, J.3
  • 21
    • 84882254968 scopus 로고    scopus 로고
    • The prevalence of meeting A1C, blood pressure, and LDL goals among people with diabetes, 1988-2010
    • Casagrande SS, Fradkin JE, Saydah SH, Rust KF, Cowie CC. The prevalence of meeting A1C, blood pressure, and LDL goals among people with diabetes, 1988-2010. Diabetes Care. 2013;36(8):2271-2279.
    • (2013) Diabetes Care , vol.36 , Issue.8 , pp. 2271-2279
    • Casagrande, S.S.1    Fradkin, J.E.2    Saydah, S.H.3    Rust, K.F.4    Cowie, C.C.5
  • 22
    • 64749089393 scopus 로고    scopus 로고
    • Inhibition of renal glucose reabsorption: A novel strategy for achieving glucose control in type 2 diabetes mellitus
    • Abdul-Ghani MA, DeFronzo RA. Inhibition of renal glucose reabsorption: a novel strategy for achieving glucose control in type 2 diabetes mellitus. Endocr Pract. 2008;14(6):782-790.
    • (2008) Endocr Pract , vol.14 , Issue.6 , pp. 782-790
    • Abdul-Ghani, M.A.1    Defronzo, R.A.2
  • 23
    • 83655193529 scopus 로고    scopus 로고
    • The role of the kidneys in glucose homeostasis: A new path towards normalizing glycaemia
    • DeFronzo RA, Davidson JA, Del Prato S. The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia. Diabetes Obes Metab. 2012;14(1):5-14.
    • (2012) Diabetes Obes Metab , vol.14 , Issue.1 , pp. 5-14
    • Defronzo, R.A.1    Davidson, J.A.2    Del Prato, S.3
  • 24
    • 84921374064 scopus 로고    scopus 로고
    • The mechanisms and therapeutic potential of SGLT2 inhibitors in diabetes mellitus
    • Vallon V. The mechanisms and therapeutic potential of SGLT2 inhibitors in diabetes mellitus. Annu Rev Med. 2015;66:255-270.
    • (2015) Annu Rev Med , vol.66 , pp. 255-270
    • Vallon, V.1
  • 25
    • 0027948971 scopus 로고
    • Molecular physiology of sodium-glucose cotransporters
    • Hediger MA, Rhoads DB. Molecular physiology of sodium-glucose cotransporters. Physiol Rev. 1994;74(4):993-1026.
    • (1994) Physiol Rev , vol.74 , Issue.4 , pp. 993-1026
    • Hediger, M.A.1    Rhoads, D.B.2
  • 26
    • 78651349221 scopus 로고    scopus 로고
    • Biology of human sodium glucose transporters
    • Wright EM, Loo DD, Hirayama BA. Biology of human sodium glucose transporters. Physiol Rev. 2011;91(2):733-794.
    • (2011) Physiol Rev , vol.91 , Issue.2 , pp. 733-794
    • Wright, E.M.1    Loo, D.D.2    Hirayama, B.A.3
  • 27
    • 33644688031 scopus 로고    scopus 로고
    • Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
    • Rahmoune H, Thompson PW, Ward JM, Smith CD, Hong G, Brown J. Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Diabetes. 2005;54(12):3427-3434.
    • (2005) Diabetes , vol.54 , Issue.12 , pp. 3427-3434
    • Rahmoune, H.1    Thompson, P.W.2    Ward, J.M.3    Smith, C.D.4    Hong, G.5    Brown, J.6
  • 28
    • 84891534541 scopus 로고    scopus 로고
    • Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30-50% of filtered glucose load in humans
    • Abdul-Ghani MA, Defronzo RA, Norton L. Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30-50% of filtered glucose load in humans. Diabetes. 2013;62(10):3324-3328.
    • (2013) Diabetes , vol.62 , Issue.10 , pp. 3324-3328
    • Abdul-Ghani, M.A.1    Defronzo, R.A.2    Norton, L.3
  • 29
    • 84994465741 scopus 로고    scopus 로고
    • Invokana (canagliflozin) tablets, for oral use [prescribing information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2016.
    • (2016) Janssen Pharmaceuticals, Inc
  • 30
    • 84994439086 scopus 로고    scopus 로고
    • Farxiga (dapagliflozin) tablets, for oral use [prescribing information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2016.
    • (2016) Astrazeneca Pharmaceuticals LP
  • 32
    • 84929676338 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin in subjects with type 2 diabetes: Systematic review and meta-analysis
    • Yang XP, Lai D, Zhong XY, Shen HP, Huang YL. Efficacy and safety of canagliflozin in subjects with type 2 diabetes: systematic review and meta-analysis. Eur J Clin Pharmacol. 2014;70(10):1149-1158.
    • (2014) Eur J Clin Pharmacol , vol.70 , Issue.10 , pp. 1149-1158
    • Yang, X.P.1    Lai, D.2    Zhong, X.Y.3    Shen, H.P.4    Huang, Y.L.5
  • 33
    • 84895484977 scopus 로고    scopus 로고
    • Dapagliflozin treatment for type 2 diabetes: A systematic review and metaanalysis of randomized controlled trials
    • Zhang M, Zhang L, Wu B, Song H, An Z, Li S. Dapagliflozin treatment for type 2 diabetes: a systematic review and metaanalysis of randomized controlled trials. Diabetes Metab Res Rev. 2014;30(3):204-221.
    • (2014) Diabetes Metab Res Rev , vol.30 , Issue.3 , pp. 204-221
    • Zhang, M.1    Zhang, L.2    Wu, B.3    Song, H.4    An, Z.5    Li, S.6
  • 34
    • 84912533839 scopus 로고    scopus 로고
    • Efficacy and safety of empagliflozin for type 2 diabetes: A systematic review and metaanalysis
    • Liakos A, Karagiannis T, Athanasiadou E, et al. Efficacy and safety of empagliflozin for type 2 diabetes: a systematic review and metaanalysis. Diabetes Obes Metab. 2014;16(10):984-993.
    • (2014) Diabetes Obes Metab , vol.16 , Issue.10 , pp. 984-993
    • Liakos, A.1    Karagiannis, T.2    Athanasiadou, E.3
  • 35
    • 84931007816 scopus 로고    scopus 로고
    • The role of sodium-glucose cotransporter 2 inhibitors in the treatment of type 2 diabetes
    • Whalen K, Miller S, Onge ES. The role of sodium-glucose cotransporter 2 inhibitors in the treatment of type 2 diabetes. Clin Ther. 2015;37(6):1150-1166.
    • (2015) Clin Ther , vol.37 , Issue.6 , pp. 1150-1166
    • Whalen, K.1    Miller, S.2    Onge, E.S.3
  • 36
    • 84893872877 scopus 로고    scopus 로고
    • Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients
    • Ferrannini E, Muscelli E, Frascerra S, et al. Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients. J Clin Invest. 2014;124(2):499-508.
    • (2014) J Clin Invest , vol.124 , Issue.2 , pp. 499-508
    • Ferrannini, E.1    Muscelli, E.2    Frascerra, S.3
  • 37
    • 84893827104 scopus 로고    scopus 로고
    • Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production
    • Merovci A, Solis-Herrera C, Daniele G, et al. Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production. J Clin Invest. 2014;124(2):509-514.
    • (2014) J Clin Invest , vol.124 , Issue.2 , pp. 509-514
    • Merovci, A.1    Solis-Herrera, C.2    Daniele, G.3
  • 38
    • 84929377076 scopus 로고    scopus 로고
    • Dapagliflozin lowers plasma glucose concentration and improves -cell function
    • Merovci A, Mari A, Solis C, et al. Dapagliflozin lowers plasma glucose concentration and improves -cell function. J Clin Endocrinol Metab. 2015;100(5):1927-1932.
    • (2015) J Clin Endocrinol Metab , vol.100 , Issue.5 , pp. 1927-1932
    • Merovci, A.1    Mari, A.2    Solis, C.3
  • 39
    • 84884167643 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial
    • Cefalu WT, Leiter LA, Yoon KH, et al. Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial. Lancet. 2013;382(9896):941-950.
    • (2013) Lancet , vol.382 , Issue.9896 , pp. 941-950
    • Cefalu, W.T.1    Leiter, L.A.2    Yoon, K.H.3
  • 40
    • 84892479365 scopus 로고    scopus 로고
    • Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin
    • Bolinder J, Ljunggren Ö, Johansson L, et al. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin. Diabetes Obes Metab. 2014;16(2):159-169.
    • (2014) Diabetes Obes Metab , vol.16 , Issue.2 , pp. 159-169
    • Bolinder, J.1    Ljunggren, Ö.2    Johansson, L.3
  • 41
    • 84908332537 scopus 로고    scopus 로고
    • Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: A 104-week randomised, activecontrolled, double-blind, phase 3 trial
    • Ridderstråle M, Andersen KR, Zeller C, Kim G, Woerle HJ, Broedl UC. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, activecontrolled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol. 2014;2(9):691-700.
    • (2014) Lancet Diabetes Endocrinol , vol.2 , Issue.9 , pp. 691-700
    • Ridderstråle, M.1    Ersen, K.R.2    Zeller, C.3    Kim, G.4    Woerle, H.J.5    Broedl, U.C.6
  • 43
    • 84901198078 scopus 로고    scopus 로고
    • Blood pressure effects of sodium-glucose co-transport 2 (SGLT2) inhibitors
    • Oliva RV, Bakris GL. Blood pressure effects of sodium-glucose co-transport 2 (SGLT2) inhibitors. J Am Soc Hypertens. 2014;8(5):330-339.
    • (2014) J am Soc Hypertens , vol.8 , Issue.5 , pp. 330-339
    • Oliva, R.V.1    Bakris, G.L.2
  • 46
    • 84962339296 scopus 로고    scopus 로고
    • Euglycemic diabetic ketoacidosis: A potential complication of treatment with sodium-glucose cotransporter 2 inhibition
    • Peters AL, Buschur EO, Buse JB, Cohan P, Diner JC, Hirsch IB. Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium-glucose cotransporter 2 inhibition. Diabetes Care. 2015;38(9):1687-1693.
    • (2015) Diabetes Care , vol.38 , Issue.9 , pp. 1687-1693
    • Peters, A.L.1    Buschur, E.O.2    Buse, J.B.3    Cohan, P.4    Diner, J.C.5    Hirsch, I.B.6
  • 47
    • 84962050697 scopus 로고    scopus 로고
    • Euglycemic diabetic ketoacidosis in a patient with type 2 diabetes after treatment with empagliflozin
    • Roach P, Skierczynski P. Euglycemic diabetic ketoacidosis in a patient with type 2 diabetes after treatment with empagliflozin. Diabetes Care. 2016;39(1):e3.
    • (2016) Diabetes Care , vol.39 , Issue.1 , pp. e3
    • Roach, P.1    Skierczynski, P.2
  • 49
    • 84962381148 scopus 로고    scopus 로고
    • Diabetic ketoacidosis and related events in the canagliflozin type 2 diabetes clinical program
    • Erondu N, Desai M, Ways K, Meininger G. Diabetic ketoacidosis and related events in the canagliflozin type 2 diabetes clinical program. Diabetes Care. 2015;38(9):1680-1686.
    • (2015) Diabetes Care , vol.38 , Issue.9 , pp. 1680-1686
    • Erondu, N.1    Desai, M.2    Ways, K.3    Meininger, G.4
  • 50
    • 84962439093 scopus 로고    scopus 로고
    • Euglycemic diabetic ketoacidosis: A predictable, detectable, and preventable safety concern with SGLT2 inhibitors
    • Rosenstock J, Ferrannini E. Euglycemic diabetic ketoacidosis: a predictable, detectable, and preventable safety concern with SGLT2 inhibitors. Diabetes Care. 2015;38(9):1638-1642.
    • (2015) Diabetes Care , vol.38 , Issue.9 , pp. 1638-1642
    • Rosenstock, J.1    Ferrannini, E.2
  • 51
    • 84898854471 scopus 로고    scopus 로고
    • Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: A systematic review and meta-analysis
    • Baker WL, Smyth LR, Riche DM, Bourret EM, Chamberlin KW, White WB. Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis. J Am Soc Hypertens. 2014;8(4):262-275.e9.
    • (2014) J am Soc Hypertens , vol.8 , Issue.4 , pp. 262-275
    • Baker, W.L.1    Smyth, L.R.2    Riche, D.M.3    Bourret, E.M.4    Chamberlin, K.W.5    White, W.B.6
  • 52
    • 84962360678 scopus 로고    scopus 로고
    • Blood pressure reduction: An added benefit of sodium-glucose cotransporter 2 inhibitors in patients with type 2 diabetes
    • Majewski C, Bakris GL. Blood pressure reduction: an added benefit of sodium-glucose cotransporter 2 inhibitors in patients with type 2 diabetes. Diabetes Care. 2015;38(3):429-430.
    • (2015) Diabetes Care , vol.38 , Issue.3 , pp. 429-430
    • Majewski, C.1    Bakris, G.L.2
  • 53
    • 65349196064 scopus 로고    scopus 로고
    • Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes
    • List JF, Woo V, Morales E, Tang W, Fiedorek FT. Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes. Diabetes Care. 2009;32(4):650-657.
    • (2009) Diabetes Care , vol.32 , Issue.4 , pp. 650-657
    • List, J.F.1    Woo, V.2    Morales, E.3    Tang, W.4    Fiedorek, F.T.5
  • 54
    • 84928382328 scopus 로고    scopus 로고
    • Are SGLT2 inhibitors reasonable antihypertensive drugs and renoprotective?
    • Lovshin JA, Gilbert RE. Are SGLT2 inhibitors reasonable antihypertensive drugs and renoprotective? Curr Hypertens Rep. 2015;17(6):551.
    • (2015) Curr Hypertens Rep , vol.17 , Issue.6 , pp. 551
    • Lovshin, J.A.1    Gilbert, R.E.2
  • 55
    • 84880850027 scopus 로고    scopus 로고
    • Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes
    • Lambers Heerspink HJ, de Zeeuw D, Wie L, Leslie B, List J. Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes. Diabetes Obes Metab. 2013;15(9):853-862.
    • (2013) Diabetes Obes Metab , vol.15 , Issue.9 , pp. 853-862
    • Lambers Heerspink, H.J.1    de Zeeuw, D.2    Wie, L.3    Leslie, B.4    List, J.5
  • 56
    • 70349695858 scopus 로고    scopus 로고
    • Longterm weight loss from lifestyle intervention benefits blood pressure? A systematic review
    • Aucott L, Rothnie H, McIntyre L, Thapa M, Waweru C, Gray D. Longterm weight loss from lifestyle intervention benefits blood pressure? A systematic review. Hypertension. 2009;54(4):756-762.
    • (2009) Hypertension , vol.54 , Issue.4 , pp. 756-762
    • Aucott, L.1    Rothnie, H.2    McIntyre, L.3    Thapa, M.4    Waweru, C.5    Gray, D.6
  • 57
    • 80055082148 scopus 로고    scopus 로고
    • Long-term effects of weight-reducing diets in hypertensive patients
    • CD008274
    • Siebenhofer A, Jeitler K, Berghold A, et al. Long-term effects of weight-reducing diets in hypertensive patients. Cochrane Database Syst Rev. 2011;(9):CD008274.
    • (2011) Cochrane Database Syst Rev , Issue.9
    • Siebenhofer, A.1    Jeitler, K.2    Berghold, A.3
  • 59
    • 84858243392 scopus 로고    scopus 로고
    • Effect of weight loss on metabolic control in people with type 2 diabetes mellitus: Systematic review
    • Souto-Gallardo ML, Gascón MB, Cruz AJ. Effect of weight loss on metabolic control in people with type 2 diabetes mellitus: systematic review. Nutr Hosp. 2011;26(6):1242-1249.
    • (2011) Nutr Hosp , vol.26 , Issue.6 , pp. 1242-1249
    • Souto-Gallardo, M.L.1    Gascón, M.B.2    Cruz, A.J.3
  • 60
    • 84939943275 scopus 로고    scopus 로고
    • Effects of canagliflozin on body weight and relationship to HbA1c and blood pressure changes in patients with type 2 diabetes
    • Cefalu WT, Stenlof K, Leiter LA, et al. Effects of canagliflozin on body weight and relationship to HbA1c and blood pressure changes in patients with type 2 diabetes. Diabetologia. 2015;58(6):1183-1187.
    • (2015) Diabetologia , vol.58 , Issue.6 , pp. 1183-1187
    • Cefalu, W.T.1    Stenlof, K.2    Leiter, L.A.3
  • 61
    • 0032707179 scopus 로고    scopus 로고
    • Glomerular hyperfiltration in experimental diabetes mellitus: Potential role of tubular reabsorption
    • Vallon V, Richter K, Blantz RC, Thomson S, Osswald H. Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption. J Am Soc Nephrol. 1999;10(12):2569-2576.
    • (1999) J am Soc Nephrol , vol.10 , Issue.12 , pp. 2569-2576
    • Vallon, V.1    Richter, K.2    Blantz, R.C.3    Thomson, S.4    Osswald, H.5
  • 62
    • 0346099293 scopus 로고    scopus 로고
    • Kidney function in early diabetes: The tubular hypothesis of glomerular filtration
    • Thomson SC, Vallon V, Blantz RC. Kidney function in early diabetes: the tubular hypothesis of glomerular filtration. Am J Physiol Renal Physiol. 2004;286(1):F8-F15.
    • (2004) Am J Physiol Renal Physiol , vol.286 , Issue.1 , pp. FF8-F15
    • Thomson, S.C.1    Vallon, V.2    Blantz, R.C.3
  • 63
    • 84914173984 scopus 로고    scopus 로고
    • Lowering plasma glucose concentration by inhibiting renal sodium-glucose cotransport
    • Abdul-Ghani MA, DeFronzo RA. Lowering plasma glucose concentration by inhibiting renal sodium-glucose cotransport. J Intern Med. 2014;276(4):352-363.
    • (2014) J Intern Med , vol.276 , Issue.4 , pp. 352-363
    • Abdul-Ghani, M.A.1    Defronzo, R.A.2
  • 64
    • 84918531200 scopus 로고    scopus 로고
    • Sodium-glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy
    • Škrtić M, Cherney DZ. Sodium-glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy. Curr Opin Nephrol Hypertens. 2015;24(1):96-103.
    • (2015) Curr Opin Nephrol Hypertens , vol.24 , Issue.1 , pp. 96-103
    • Škrtić, M.1    Cherney, D.Z.2
  • 65
    • 84945455839 scopus 로고    scopus 로고
    • Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes
    • Chilton R, Tikkanen I, Cannon CP, et al. Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes. Diabetes Obes Metab. 2015;17(12):1180-1193.
    • (2015) Diabetes Obes Metab , vol.17 , Issue.12 , pp. 1180-1193
    • Chilton, R.1    Tikkanen, I.2    Cannon, C.P.3
  • 66
    • 84892959743 scopus 로고    scopus 로고
    • The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus
    • Cherney DZ, Perkins BA, Soleymanlou N, et al. The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus. Cardiovasc Diabetol. 2014;13:28.
    • (2014) Cardiovasc Diabetol , vol.13 , pp. 28
    • Cherney, D.Z.1    Perkins, B.A.2    Soleymanlou, N.3
  • 67
    • 84874291673 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise
    • Stenlöf K, Cefalu WT, Kim KA, et al. Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise. Diabetes Obes Metab. 2013;15(4):372-382.
    • (2013) Diabetes Obes Metab , vol.15 , Issue.4 , pp. 372-382
    • Stenlöf, K.1    Cefalu, W.T.2    Kim, K.A.3
  • 68
    • 77956921439 scopus 로고    scopus 로고
    • Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: A randomized, double-blind, placebo-controlled, phase 3 trial
    • Ferrannini E, Ramos SJ, Salsali A, Tang W, List JF. Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial. Diabetes Care. 2010;33(10):2217-2224.
    • (2010) Diabetes Care , vol.33 , Issue.10 , pp. 2217-2224
    • Ferrannini, E.1    Ramos, S.J.2    Salsali, A.3    Tang, W.4    List, J.F.5
  • 69
    • 84885954870 scopus 로고    scopus 로고
    • Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: A randomised, double-blind, placebo-controlled, phase 3 trial
    • Roden M, Weng J, Eilbracht J, et al. Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Diabetes Endocrinol. 2013;1(3):208-219.
    • (2013) Lancet Diabetes Endocrinol , vol.1 , Issue.3 , pp. 208-219
    • Roden, M.1    Weng, J.2    Eilbracht, J.3
  • 70
    • 84887997289 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin compared with placebo and sitagliptin in patients with type 2 diabetes on background metformin monotherapy: A randomised trial
    • Lavalle-González FJ, Januszewicz A, Davidson J, et al. Efficacy and safety of canagliflozin compared with placebo and sitagliptin in patients with type 2 diabetes on background metformin monotherapy: a randomised trial. Diabetologia. 2013;56(12):2582-2592.
    • (2013) Diabetologia , vol.56 , Issue.12 , pp. 2582-2592
    • Lavalle-González, F.J.1    Januszewicz, A.2    Davidson, J.3
  • 71
    • 77953857048 scopus 로고    scopus 로고
    • Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: A randomised, double-blind, placebo-controlled trial
    • Bailey CJ, Gross JL, Pieters A, Bastien A, List JF. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial. Lancet. 2010;375(9733):2223-2233.
    • (2010) Lancet , vol.375 , Issue.9733 , pp. 2223-2233
    • Bailey, C.J.1    Gross, J.L.2    Pieters, A.3    Bastien, A.4    List, J.F.5
  • 72
    • 84901455931 scopus 로고    scopus 로고
    • Empagliflozin as addon to metformin in patients with type 2 diabetes: A 24-week, randomized, double-blind, placebo-controlled trial
    • Häring HU, Merker L, Seewaldt-Becker E, et al. Empagliflozin as addon to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial. Diabetes Care. 2014;37(6): 1650-1659.
    • (2014) Diabetes Care , vol.37 , Issue.6 , pp. 1650-1659
    • Häring, H.U.1    Merker, L.2    Seewaldt-Becker, E.3
  • 73
    • 84888059660 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin and sulphonylurea: A randomised trial
    • Wilding JP, Charpentier G, Hollander P, et al. Efficacy and safety of canagliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin and sulphonylurea: a randomised trial. Int J Clin Pract. 2013;67(12):1267-1282.
    • (2013) Int J Clin Pract , vol.67 , Issue.12 , pp. 1267-1282
    • Wilding, J.P.1    Charpentier, G.2    Hollander, P.3
  • 74
    • 84930825790 scopus 로고    scopus 로고
    • Dapagliflozin improves glycemic control and reduces body weight as addon therapy to metformin plus sulfonylurea: A 24-week randomized, double-blind clinical trial
    • Matthaei S, Bowering K, Rohwedder K, Grohl A, Parikh S. Dapagliflozin improves glycemic control and reduces body weight as addon therapy to metformin plus sulfonylurea: a 24-week randomized, double-blind clinical trial. Diabetes Care. 2015;38(3):365-372.
    • (2015) Diabetes Care , vol.38 , Issue.3 , pp. 365-372
    • Matthaei, S.1    Bowering, K.2    Rohwedder, K.3    Grohl, A.4    Parikh, S.5
  • 75
    • 84885952950 scopus 로고    scopus 로고
    • Empagliflozin as addon to metformin plus sulfonylurea in patients with type 2 diabetes: A 24-week, randomized, double-blind, placebo-controlled trial
    • Häring HU, Merker L, Seewaldt-Becker E, et al. Empagliflozin as addon to metformin plus sulfonylurea in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial. Diabetes Care. 2013;36(11):3396-3404.
    • (2013) Diabetes Care , vol.36 , Issue.11 , pp. 3396-3404
    • Häring, H.U.1    Merker, L.2    Seewaldt-Becker, E.3
  • 76
    • 84898791440 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes on background metformin and pioglitazone
    • Forst T, Guthrie R, Goldenberg R, et al. Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes on background metformin and pioglitazone. Diabetes Obes Metab. 2014;16(5):467-477.
    • (2014) Diabetes Obes Metab , vol.16 , Issue.5 , pp. 467-477
    • Forst, T.1    Guthrie, R.2    Goldenberg, R.3
  • 77
    • 84862875221 scopus 로고    scopus 로고
    • Effects of dapagliflozin, an SGLT2 inhibitor, on HbA1c, body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy
    • Rosenstock J, Vico M, Wei L, Salsali A, List JF. Effects of dapagliflozin, an SGLT2 inhibitor, on HbA1c, body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy. Diabetes Care. 2012;35(7):1473-1478.
    • (2012) Diabetes Care , vol.35 , Issue.7 , pp. 1473-1478
    • Rosenstock, J.1    Vico, M.2    Wei, L.3    Salsali, A.4    List, J.F.5
  • 78
    • 84892477577 scopus 로고    scopus 로고
    • Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: A 24-week, randomized, placebo-controlled trial
    • Kovacs CS, Seshiah V, Swallow R, et al. Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial. Diabetes Obes Metab. 2014;16(2):147-158.
    • (2014) Diabetes Obes Metab , vol.16 , Issue.2 , pp. 147-158
    • Kovacs, C.S.1    Seshiah, V.2    Swallow, R.3
  • 79
    • 84930844091 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin, an inhibitor of sodium-glucose cotransporter 2, when used in conjunction with insulin therapy in patients with type 2 diabetes
    • Neal B, Perkovic V, de Zeeuw D, et al. Efficacy and safety of canagliflozin, an inhibitor of sodium-glucose cotransporter 2, when used in conjunction with insulin therapy in patients with type 2 diabetes. Diabetes Care. 2015;38(3):403-411.
    • (2015) Diabetes Care , vol.38 , Issue.3 , pp. 403-411
    • Neal, B.1    Perkovic, V.2    de Zeeuw, D.3
  • 80
    • 84858323889 scopus 로고    scopus 로고
    • Long-term efficacy of dapagliflozin in patients with type 2 diabetes mellitus receiving high doses of insulin: A randomized trial
    • Wilding JP, Woo V, Soler NG, et al. Long-term efficacy of dapagliflozin in patients with type 2 diabetes mellitus receiving high doses of insulin: a randomized trial. Ann Intern Med. 2012;156(6):405-415.
    • (2012) Ann Intern Med , vol.156 , Issue.6 , pp. 405-415
    • Wilding, J.P.1    Woo, V.2    Soler, N.G.3
  • 81
    • 84942294658 scopus 로고    scopus 로고
    • Impact of empagliflozin added on to basal insulin in type 2 diabetes inadequately controlled on basal insulin: A 78-week randomized, double-blind, placebo-controlled trial
    • Rosenstock J, Jelaska A, Zeller C, Kim G, Broedl UC, Woerle HJ. Impact of empagliflozin added on to basal insulin in type 2 diabetes inadequately controlled on basal insulin: a 78-week randomized, double-blind, placebo-controlled trial. Diabetes Obes Metab. 2015;17(10):936-948.
    • (2015) Diabetes Obes Metab , vol.17 , Issue.10 , pp. 936-948
    • Rosenstock, J.1    Jelaska, A.2    Zeller, C.3    Kim, G.4    Broedl, U.C.5    Woerle, H.J.6
  • 82
    • 84919681923 scopus 로고    scopus 로고
    • Effect of canagliflozin on blood pressure and adverse events related to osmotic diuresis and reduced intravascular volume in patients with type 2 diabetes mellitus
    • Weir MR, Januszewicz A, Gilbert RE, et al. Effect of canagliflozin on blood pressure and adverse events related to osmotic diuresis and reduced intravascular volume in patients with type 2 diabetes mellitus. J Clin Hypertens (Greenwich). 2014;16(12):875-882.
    • (2014) J Clin Hypertens (Greenwich) , vol.16 , Issue.12 , pp. 875-882
    • Weir, M.R.1    Januszewicz, A.2    Gilbert, R.E.3
  • 83
    • 84938687573 scopus 로고    scopus 로고
    • Dapagliflozin lowers blood pressure in hypertensive and non-hypertensive patients with type 2 diabetes
    • Sjöström CD, Johansson P, Ptaszynska A, List J, Johnsson E. Dapagliflozin lowers blood pressure in hypertensive and non-hypertensive patients with type 2 diabetes. Diab Vasc Dis Res. 2015;12(5):352-358.
    • (2015) Diab Vasc Dis Res , vol.12 , Issue.5 , pp. 352-358
    • Sjöström, C.D.1    Johansson, P.2    Ptaszynska, A.3    List, J.4    Johnsson, E.5
  • 84
    • 84959460390 scopus 로고    scopus 로고
    • Blood pressure and glycaemic effects of dapagliflozin versus placebo in patients with type 2 diabetes on combination antihypertensive therapy: A randomised, double-blind, placebo-controlled, phase 3 study
    • Weber MA, Mansfield TA, Cain VA, Iqbal N, Parikh S, Ptaszynska A. Blood pressure and glycaemic effects of dapagliflozin versus placebo in patients with type 2 diabetes on combination antihypertensive therapy: a randomised, double-blind, placebo-controlled, phase 3 study. Lancet Diabetes Endocrinol. 2016;4(3):211-220.
    • (2016) Lancet Diabetes Endocrinol , vol.4 , Issue.3 , pp. 211-220
    • Weber, M.A.1    Mansfield, T.A.2    Cain, V.A.3    Iqbal, N.4    Parikh, S.5    Ptaszynska, A.6
  • 85
    • 84928196614 scopus 로고    scopus 로고
    • Empagliflozin reduces blood pressure in patients with type 2 diabetes and hypertension
    • Tikkanen I, Narko K, Zeller C, et al. Empagliflozin reduces blood pressure in patients with type 2 diabetes and hypertension. Diabetes Care. 2015;38(3):420-428.
    • (2015) Diabetes Care , vol.38 , Issue.3 , pp. 420-428
    • Tikkanen, I.1    Narko, K.2    Zeller, C.3
  • 86
    • 84953638180 scopus 로고    scopus 로고
    • Reductions in mean 24-hour ambulatory blood pressure after 6-week treatment with canagliflozin in patients with type 2 diabetes mellitus and hypertension
    • Townsend RR, Machin I, Ren J, et al. Reductions in mean 24-hour ambulatory blood pressure after 6-week treatment with canagliflozin in patients with type 2 diabetes mellitus and hypertension. J Clin Hypertens (Greenwich). 2016;18(1):43-52.
    • (2016) J Clin Hypertens (Greenwich) , vol.18 , Issue.1 , pp. 43-52
    • Townsend, R.R.1    Machin, I.2    Ren, J.3
  • 87
    • 84884202005 scopus 로고    scopus 로고
    • European Society of Hypertension position paper on ambulatory blood pressure monitoring
    • O’Brien E, Parati G, Stergiou G, et al. European Society of Hypertension position paper on ambulatory blood pressure monitoring. J Hypertens. 2013;31(9):1731-1768.
    • (2013) J Hypertens , vol.31 , Issue.9 , pp. 1731-1768
    • O’Brien, E.1    Parati, G.2    Stergiou, G.3
  • 88
    • 84880930315 scopus 로고    scopus 로고
    • ESH/ESC guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    • Mancia G, Fagard R, Narkiewicz K, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J. 2013;34(28):2159-2219.
    • (2013) Eur Heart J , vol.34 , Issue.28 , pp. 2159-2219
    • Mancia, G.1    Fagard, R.2    Narkiewicz, K.3
  • 89
    • 77953444272 scopus 로고    scopus 로고
    • Can nocturnal hypertension predict cardiovascular risk?
    • Friedman O, Logan AG. Can nocturnal hypertension predict cardiovascular risk? Integr Blood Press Control. 2009;2:25-37.
    • (2009) Integr Blood Press Control , vol.2 , pp. 25-37
    • Friedman, O.1    Logan, A.G.2
  • 90
    • 84898861509 scopus 로고    scopus 로고
    • Characterization of type 2 diabetes mellitus burden by age and ethnic groups based on a nationwide survey
    • Lopez JM, Bailey RA, Rupnow MF, Annunziata K. Characterization of type 2 diabetes mellitus burden by age and ethnic groups based on a nationwide survey. Clin Ther. 2014;36(4):494-506.
    • (2014) Clin Ther , vol.36 , Issue.4 , pp. 494-506
    • Lopez, J.M.1    Bailey, R.A.2    Rupnow, M.F.3    Annunziata, K.4
  • 91
    • 84940775310 scopus 로고    scopus 로고
    • The efficacy and safety of canagliflozin across racial groups in patients with type 2 diabetes mellitus
    • Gavin JR III, Davies MJ, Davies M, Vijapurkar U, Alba M, Meininger G. The efficacy and safety of canagliflozin across racial groups in patients with type 2 diabetes mellitus. Curr Med Res Opin. 2015;31(9):1693-1702.
    • (2015) Curr Med Res Opin , vol.31 , Issue.9 , pp. 1693-1702
    • Gavin, J.R.1    Davies, M.J.2    Davies, M.3    Vijapurkar, U.4    Alba, M.5    Meininger, G.6
  • 93
    • 84992050918 scopus 로고    scopus 로고
    • NLM identifier: NCT01032629. Accessed January 8, 2016
    • Janssen Research & Development. Canagliflozin cardiovascular assessment study (CANVAS). Available from: https://www.clinicaltrials.gov/ ct2/show/NCT01032629. NLM identifier: NCT01032629. Accessed January 8, 2016.
    • Canagliflozin Cardiovascular Assessment Study (CANVAS)
  • 94
    • 84880924263 scopus 로고    scopus 로고
    • Rationale, design, and baseline characteristics of the Canagliflozin Cardiovascular Assessment Study (CANVAS): A randomized placebo-controlled trial
    • Neal B, Perkovic V, de Zeeuw D, et al. Rationale, design, and baseline characteristics of the Canagliflozin Cardiovascular Assessment Study (CANVAS): a randomized placebo-controlled trial. Am Heart J. 2013;166(2):217-223.e11.
    • (2013) Am Heart J , vol.166 , Issue.2 , pp. 217-223
    • Neal, B.1    Perkovic, V.2    de Zeeuw, D.3
  • 96
    • 84963908215 scopus 로고    scopus 로고
    • Accessed April 13, 2016
    • TIMI Study Group. DECLARE-TIMI 58. Available from: http://www.timi.org/index.php?pagedeclare-timi-58. Accessed April 13, 2016.
    • DECLARE-TIMI 58
  • 98
    • 84944800184 scopus 로고    scopus 로고
    • Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
    • Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015; 373(22):2117-2128.
    • (2015) N Engl J Med , vol.373 , Issue.22 , pp. 2117-2128
    • Zinman, B.1    Wanner, C.2    Lachin, J.M.3
  • 99
    • 84964773926 scopus 로고    scopus 로고
    • SGLT2 inhibitors and cardiovascular risk: Lessons learned from the EMPA-REG OUTCOME study
    • Abdul-Ghani M, Del Prato S, Chilton R, DeFronzo RA. SGLT2 inhibitors and cardiovascular risk: lessons learned from the EMPA-REG OUTCOME study. Diabetes Care. 2016;39(5):717-725.
    • (2016) Diabetes Care , vol.39 , Issue.5 , pp. 717-725
    • Abdul-Ghani, M.1    Del Prato, S.2    Chilton, R.3    Defronzo, R.A.4
  • 100
    • 79251556005 scopus 로고    scopus 로고
    • The progression of hypertensive heart disease
    • Drazner MH. The progression of hypertensive heart disease. Circulation. 2011;123(3):327-334.
    • (2011) Circulation , vol.123 , Issue.3 , pp. 327-334
    • Drazner, M.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.