Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt signaling pathway

American Journal of Nephrology

Volumn 28, Issue 2, 2008, Pages 290-297

  Lin, Chun Liang ^a,b   Cheng, Ho ^b   Tung, Chun Wu ^a   Huang, Wei Jan ^b   Chang, Pey Jium ^a   Yang, Jen Tsung ^b   Wang, Jeng Yi ^b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Catenin; Apoptosis; Diabetes; GSK 3 ; Simvastatin; Wnt5a

Indexed keywords

BETA CATENIN; CASPASE 3; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; WNT PROTEIN; WNT5A PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DISEASE COURSE; DOWN REGULATION; GLOMERULUS EPITHELIUM; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; IMMUNOHISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MESANGIUM CELL; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BETA CATENIN; CASPASE 3; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; ENZYME ACTIVATION; GLUCOSE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MESANGIAL CELLS; MODELS, BIOLOGICAL; RATS; SIGNAL TRANSDUCTION; SIMVASTATIN; WNT PROTEINS;

EID: 38349045501     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000111142     Document Type: Article

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