Detection of cytosolic shigella flexneri via a C-terminal triple-arginine motif of GBP1 inhibits actin-based motility

mBio

Volumn 8, Issue 6, 2017, Pages

  Piro, Anthony S ^a   Hernandez, Dulcemaria ^a   Luoma, Sarah ^a   Feeley, Eric M ^a   Finethy, Ryan ^a   Yirga, Azeb ^a   Frickel, Eva M ^b   Lesser, Cammie F ^c,d   Coersa, Jörn ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Actin; Burkholderia; Dynamin; E3 ligase; Gram negative bacteria; Guanylate binding protein; Interferons; IpaH9.8; LPS; O antigen; Shigella; Ubiquitination

Indexed keywords

ACTIN; ARGININE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN 2; GUANINE NUCLEOTIDE BINDING PROTEIN 3; GUANINE NUCLEOTIDE BINDING PROTEIN 4; GUANINE NUCLEOTIDE BINDING PROTEIN 6; LIPOPOLYSACCHARIDE; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; GBP1 PROTEIN, HUMAN; IPAH PROTEIN, SHIGELLA FLEXNERI; LIPOPOLYSACCHARIDE A; O ANTIGEN; VIRULENCE FACTOR;

A-549 CELL LINE; ANIMAL CELL; ARTICLE; BACTERIAL CELL; BURKHOLDERIA THAILANDENSIS; CARBOXY TERMINAL SEQUENCE; CELL MOTILITY; CELL VACUOLE; CONTROLLED STUDY; CYTOSOL; HELA CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN TARGETING; SHIGELLA FLEXNERI; STRUCTURE ACTIVITY RELATION; WILD TYPE; BURKHOLDERIA; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; MUTATION; PATHOGENICITY; PHYSIOLOGY; SECRETION (PROCESS); UBIQUITINATION;

ACTINS; AMINO ACID MOTIFS; ANTIGENS, BACTERIAL; ARGININE; BACTERIAL PROTEINS; BURKHOLDERIA; CYTOSOL; GTP-BINDING PROTEINS; HELA CELLS; HUMANS; LIPOPOLYSACCHARIDES; MUTATION; O ANTIGENS; SHIGELLA FLEXNERI; UBIQUITINATION; VIRULENCE FACTORS;

EID: 85039923954     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01979-17     Document Type: Article

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