Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence

Nature

Volumn 551, Issue 7680, 2017, Pages 378-383

  Li, Peng ^a,b   Jiang, Wei ^b   Yu, Qin ^b   Liu, Wang ^b   Zhou, Ping ^b   Li, Jun ^b   Xu, Junjie ^b   Xu, Bo ^b   Wang, Fengchao ^b   Shao, Feng ^b  

^a PEKING UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GALECTIN 3; GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN 2; GUANINE NUCLEOTIDE BINDING PROTEIN 3; GUANINE NUCLEOTIDE BINDING PROTEIN 5; GUANINE NUCLEOTIDE BINDING PROTEIN 7; TUBULIN; UBIQUITIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; GBP1 PROTEIN, HUMAN; GBP2 PROTEIN, MOUSE; GUANOSINE TRIPHOSPHATE; INTERFERON; PROTEASOME; UBIQUITIN PROTEIN LIGASE;

ANTIGEN; ANTIMICROBIAL ACTIVITY; BACTERIUM; CELLS AND CELL COMPONENTS; CYTOPLASM; DEFENSE MECHANISM; DEGRADATION; DYSENTERY; GENE; HOST; MUTATION; PLASMID; PROTEIN; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FARNESYLATION; FEMALE; HELA CELL LINE; HOST RESISTANCE; HUMAN; HUMAN CELL; LISTERIA MONOCYTOGENES; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; SHIGELLA FLEXNERI; SHIGELLOSIS; TRANSPOSON; TYPE III SECRETION SYSTEM; UBIQUITINATION; WILD TYPE; YERSINIA ENTEROCOLITICA; ANIMAL; CHEMISTRY; CYTOPLASM; DEFICIENCY; ENZYMOLOGY; GENE DELETION; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; MACROPHAGE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; VIRULENCE;

BACTERIA (MICROORGANISMS); MUS; NEGIBACTERIA; SHIGELLA; SHIGELLA FLEXNERI;

ANIMALS; BACTERIAL PROTEINS; CYTOPLASM; FEMALE; GENE DELETION; GTP-BINDING PROTEINS; GUANOSINE TRIPHOSPHATE; HELA CELLS; HUMANS; INTERFERONS; MACROPHAGES; MICE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; SHIGELLA FLEXNERI; TYPE III SECRETION SYSTEMS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VIRULENCE;

EID: 85034419593     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature24467     Document Type: Article

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