Inflammasome activation by bacterial outer membrane vesicles requires guanylate binding proteins

mBio

Volumn 8, Issue 5, 2017, Pages

  Finethy, Ryan ^a   Luoma, Sarah ^a   Orench Rivera, Nichole ^a   Feeley, Eric M ^a   Haldar, Arun K ^a   Yamamoto, Masahiro ^b   Kanneganti, Thirumala Devi ^c   Kuehn, Meta J ^a   Coers, Jörn ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b OSAKA UNIVERSITY   (Japan)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Caspase 11; GBP2; GBP5; Guanylate binding proteins; Inflammasome; Interferons; Lipopolysaccharide; LPS; OMVs; Outer membrane vesicles; Sepsis

Indexed keywords

CASPASE 11; GUANINE NUCLEOTIDE BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; CASP11 PROTEIN, MOUSE; CASPASE; OUTER MEMBRANE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL OUTER MEMBRANE; CELL DEATH; CELL VACUOLE; CONTROLLED STUDY; CYTOKINE RELEASE; EMBRYO; ENZYME ACTIVATION; ESCHERICHIA COLI; FEMALE; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; MALE; MORTALITY RATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; SEPSIS; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CYTOSOL; GENETICS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PYROPTOSIS; SECRETORY VESICLE;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; CASPASES; CELLS, CULTURED; CYTOSOL; ENZYME ACTIVATION; ESCHERICHIA COLI; GTP-BINDING PROTEINS; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-18; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PYROPTOSIS; SECRETORY VESICLES;

EID: 85033730214     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01188-17     Document Type: Article

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