Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases

Cell Host and Microbe

Volumn 22, Issue 1, 2017, Pages 74-85.e7

  Biering, Scott B ^a   Choi, Jayoung ^a   Halstrom, Rachel A ^a   Brown, Hailey M ^a   Beatty, Wandy L ^b   Lee, Sanghyun ^b   McCune, Broc T ^b   Dominici, Erin ^a   Williams, Lelia E ^a   Orchard, Robert C ^b   Wilen, Craig B ^b   Yamamoto, Masahiro ^c   Coers, Jörn ^d   Taylor, Gregory A ^d,e   Hwang, Seungmin ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c OSAKA UNIVERSITY   (Japan)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e DURHAM VA HEALTH CARE SYSTEM   (United States)

Author keywords

autophagy; GBP; GTPase; interferon; IRG; LC3; replication; RNA; targeting; virus

Indexed keywords

GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; INTERFERON; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; UNCLASSIFIED DRUG; CARRIER PROTEIN; MAP1LC3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; AUTOPHAGY; CELL VACUOLE; COMPARATIVE STUDY; CONJUGATION; CONTROLLED STUDY; CYTOSOL; EMBRYO; ENZYME LOCALIZATION; FEMALE; FIBROBLAST; GENETIC CONSERVATION; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNITY; IN VITRO STUDY; IN VIVO STUDY; INTERFERON INDUCTION; MALE; MEMBRANE STRUCTURE; MEMBRANE VESICLE; MOUSE; NONHUMAN; NOROVIRUS; NOROVIRUS INFECTION; PRIORITY JOURNAL; REPLICATION COMPLEX; VIRUS REPLICATION; ANIMAL; C57BL MOUSE; CALICIVIRUS INFECTION; CELL LINE; DRUG EFFECTS; GENE KNOCKDOWN; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; MACROPHAGE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; RAW 264.7 CELL LINE; VIRAL PLAQUE ASSAY; VIROLOGY;

ANIMALS; AUTOPHAGY; CALICIVIRIDAE INFECTIONS; CARRIER PROTEINS; CELL LINE; CYTOSOL; FEMALE; FIBROBLASTS; GENE KNOCKDOWN TECHNIQUES; GTP PHOSPHOHYDROLASES; HELA CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON-GAMMA; INTERFERONS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; NOROVIRUS; RAW 264.7 CELLS; VACUOLES; VIRAL PLAQUE ASSAY; VIRUS REPLICATION;

EID: 85021318986     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.06.005     Document Type: Article

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