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Volumn 10, Issue 6, 2017, Pages 1361-1374

The regulation of gut mucosal IgA B-cell responses: Recent developments

Author keywords

[No Author keywords available]

Indexed keywords

APRIL PROTEIN; B CELL ACTIVATING FACTOR; B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN A; INTERLEUKIN 21; RETINOIC ACID; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSCRIPTION FACTOR RUNX3; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; VACCINE;

EID: 85031755492     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2017.62     Document Type: Review
Times cited : (140)

References (194)
  • 1
    • 0015231977 scopus 로고
    • Immunoglobulin M and secretory immunoglobulin A: Presence of a common polypeptide chain different from light chains
    • Mestecky, J., Zikan, J. & Butler, W.T. Immunoglobulin M and secretory immunoglobulin A: presence of a common polypeptide chain different from light chains. Science 171, 1163-1165 (1971).
    • (1971) Science , vol.171 , pp. 1163-1165
    • Mestecky, J.1    Zikan, J.2    Butler, W.T.3
  • 2
    • 0014964145 scopus 로고
    • Noval subunit in secretory IgA
    • Halpern, M.S. & Koshland, M.E. Noval subunit in secretory IgA. Nature 228, 1276-1278 (1970).
    • (1970) Nature , vol.228 , pp. 1276-1278
    • Halpern, M.S.1    Koshland, M.E.2
  • 3
    • 84883713293 scopus 로고    scopus 로고
    • Secretory iga: Designed for anti-microbial defense
    • Brandtzaeg, P. Secretory IgA: Designed for Anti-Microbial Defense. Front. Immunol. 4, 222 (2013).
    • (2013) Front. Immunol. , vol.4 , pp. 222
    • Brandtzaeg, P.1
  • 4
    • 84883673597 scopus 로고    scopus 로고
    • Multi-faceted functions of secretory IgA at mucosal surfaces
    • Corthé sy, B. Multi-faceted functions of secretory IgA at mucosal surfaces. Front. Immunol. 4, 185 (2013).
    • (2013) Front. Immunol. , vol.4 , pp. 185
    • Corthé Sy, B.1
  • 5
    • 84890336529 scopus 로고    scopus 로고
    • The gastrointestinal frontier: Iga and viruses
    • Blutt, S.E. & Conner, M.E. The Gastrointestinal Frontier: IgA and Viruses. Front. Immunol. 4, 402 (2013).
    • (2013) Front. Immunol. , vol.4 , pp. 402
    • Blutt, S.E.1    Conner, M.E.2
  • 6
    • 34447099136 scopus 로고    scopus 로고
    • Induction of secretory immunity and memory at mucosal surfaces
    • Brandtzaeg, P. Induction of secretory immunity and memory at mucosal surfaces. Vaccine 25, 5467-5484 (2007).
    • (2007) Vaccine , vol.25 , pp. 5467-5484
    • Brandtzaeg, P.1
  • 7
    • 84962433328 scopus 로고    scopus 로고
    • Secretory iga in the coordination of establishment and maintenance of the microbiota
    • Pabst, O., Cerovic, V. & Hornef, M. Secretory IgA in the Coordination of Establishment and Maintenance of the Microbiota. Trends Immunol. 37, 287-296 (2016).
    • (2016) Trends Immunol. , vol.37 , pp. 287-296
    • Pabst, O.1    Cerovic, V.2    Hornef, M.3
  • 8
    • 85017350184 scopus 로고    scopus 로고
    • High-avidity IgA protects the intestine by enchaining growing bacteria
    • Moor, K. et al. High-avidity IgA protects the intestine by enchaining growing bacteria. Nature 544, 498-502 (2017).
    • (2017) Nature , vol.544 , pp. 498-502
    • Moor, K.1
  • 9
    • 84864338756 scopus 로고    scopus 로고
    • Recent progress in mucosal vaccine development: Potential and limitations
    • Lycke, N. Recent progress in mucosal vaccine development: potential and limitations. Nat. Rev. Immunol. 12, 592-605 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 592-605
    • Lycke, N.1
  • 10
    • 84939570686 scopus 로고    scopus 로고
    • The bilateral responsiveness between intestinal microbes and IgA
    • Macpherson, A.J., Kö ller, Y. & McCoy, K.D. The bilateral responsiveness between intestinal microbes and IgA. Trends Immunol. 36, 460-470 (2015).
    • (2015) Trends Immunol. , vol.36 , pp. 460-470
    • Macpherson, A.J.1    Kö Ller, Y.2    McCoy, K.D.3
  • 11
    • 85011085755 scopus 로고    scopus 로고
    • Mechanisms of inflammation-driven bacterial dysbiosis in the gut
    • Zeng, M.Y., Inohara, N. & Nunez, G. Mechanisms of inflammation-driven bacterial dysbiosis in the gut. Mucosal Immunol. 10, 18-26 (2017).
    • (2017) Mucosal Immunol. , vol.10 , pp. 18-26
    • Zeng, M.Y.1    Inohara, N.2    Nunez, G.3
  • 12
    • 84937814800 scopus 로고    scopus 로고
    • Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota
    • Lindner, C. et al. Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota. Nat. Immunol. 16, 880-888 (2015).
    • (2015) Nat. Immunol. , vol.16 , pp. 880-888
    • Lindner, C.1
  • 13
    • 84962605055 scopus 로고    scopus 로고
    • The maternal microbiota drives early postnatal innate immune development
    • de Agü ero, M.G. et al. The maternal microbiota drives early postnatal innate immune development. Science 351, 1296-1302 (2016).
    • (2016) Science , vol.351 , pp. 1296-1302
    • De Agü Ero, M.G.1
  • 14
    • 84941647683 scopus 로고    scopus 로고
    • Balb/c and c57bl/6 mice differ in polyreactive iga abundance, which impacts the generation of antigen-specific iga and microbiota diversity
    • Fransen, F. et al. BALB/c and C57BL/6 Mice Differ in Polyreactive IgA Abundance, which Impacts the Generation of Antigen-Specific IgA and Microbiota Diversity. Immunity 43, 527-540 (2015).
    • (2015) Immunity , vol.43 , pp. 527-540
    • Fransen, F.1
  • 15
    • 84968543814 scopus 로고    scopus 로고
    • The variegated aspects of Immunoglobulin A
    • Zagato, E., Mazzini, E. & Rescigno, M. The variegated aspects of Immunoglobulin A. Immunol. Lett. 178, 45-49 (2016).
    • (2016) Immunol. Lett. , vol.178 , pp. 45-49
    • Zagato, E.1    Mazzini, E.2    Rescigno, M.3
  • 16
    • 84982255270 scopus 로고    scopus 로고
    • The human intestinal B-cell response
    • Spencer, J. & Sollid, L.M. The human intestinal B-cell response. Mucosal Immunol. 9, 1113-1124 (2016).
    • (2016) Mucosal Immunol. , vol.9 , pp. 1113-1124
    • Spencer, J.1    Sollid, L.M.2
  • 17
    • 48649110421 scopus 로고    scopus 로고
    • Terminology: Nomenclature of mucosa-associated lymphoid tissue
    • Brandtzaeg, P., Kiyono, H., Pabst, R. & Russell, M.W. Terminology: nomenclature of mucosa-associated lymphoid tissue. Mucosal Immunol. 1, 31-37 (2008).
    • (2008) Mucosal Immunol. , vol.1 , pp. 31-37
    • Brandtzaeg, P.1    Kiyono, H.2    Pabst, R.3    Russell, M.W.4
  • 18
    • 84884239043 scopus 로고    scopus 로고
    • Lung dendritic cells induce migration of protective Tcells to the gastrointestinal tract
    • Ruane, D. et al. Lung dendritic cells induce migration of protective Tcells to the gastrointestinal tract. J. Exp. Med. 210, 1871-1888 (2013).
    • (2013) J. Exp. Med. , vol.210 , pp. 1871-1888
    • Ruane, D.1
  • 19
    • 77952318832 scopus 로고    scopus 로고
    • Intestinal bacteria and the regulation of immune cell homeostasis
    • Hill, D.A. & Artis, D. Intestinal bacteria and the regulation of immune cell homeostasis. Annu. Rev. Immunol. 28, 623-667 (2010).
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 623-667
    • Hill, D.A.1    Artis, D.2
  • 20
    • 84960121372 scopus 로고    scopus 로고
    • Intestinal M cells
    • Ohno, H. Intestinal M cells. J. Biochem. 159, 151-160 (2016).
    • (2016) J. Biochem. , vol.159 , pp. 151-160
    • Ohno, H.1
  • 21
    • 84864147310 scopus 로고    scopus 로고
    • The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells
    • Kanaya, T. et al. The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells. Nat. Immunol. 13, 729-736 (2012).
    • (2012) Nat. Immunol. , vol.13 , pp. 729-736
    • Kanaya, T.1
  • 22
    • 84879398558 scopus 로고    scopus 로고
    • Transcription factor Spi-B-dependent and-independent pathways for the development of Peyer's patch M cells
    • Sato, S. et al. Transcription factor Spi-B-dependent and-independent pathways for the development of Peyer's patch M cells. Mucosal Immunol. 6, 838-846 (2013).
    • (2013) Mucosal Immunol. , vol.6 , pp. 838-846
    • Sato, S.1
  • 23
    • 84879336857 scopus 로고    scopus 로고
    • Microfold (M) cells: Important immunosurveillance posts in the intestinal epithelium
    • Mabbott, N.A., Donaldson, D.S., Ohno, H., Williams, I.R. & Mahajan, A. Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium. Mucosal Immunol. 6, 666-677 (2013).
    • (2013) Mucosal Immunol. , vol.6 , pp. 666-677
    • Mabbott, N.A.1    Donaldson, D.S.2    Ohno, H.3    Williams, I.R.4    Mahajan, A.5
  • 24
    • 85031754326 scopus 로고    scopus 로고
    • Identification of subepithelial mesenchymal cells that induce IgA and diversify gut microbiota
    • Nagashima, K. et al. Identification of subepithelial mesenchymal cells that induce IgA and diversify gut microbiota. Nat. Immunol. 9, 618 (2017).
    • (2017) Nat. Immunol. , vol.9 , pp. 618
    • Nagashima, K.1
  • 25
    • 84975824503 scopus 로고    scopus 로고
    • Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria
    • Rios, D. et al. Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria. Mucosal Immunol. 9, 907-916 (2016).
    • (2016) Mucosal Immunol. , vol.9 , pp. 907-916
    • Rios, D.1
  • 26
    • 84863230541 scopus 로고    scopus 로고
    • Goblet cells deliver luminal antigen to CD103() dendritic cells in the small intestine
    • McDole, J.R. et al. Goblet cells deliver luminal antigen to CD103() dendritic cells in the small intestine. Nature 483, 345-349 (2012).
    • (2012) Nature , vol.483 , pp. 345-349
    • McDole, J.R.1
  • 27
    • 84886280379 scopus 로고    scopus 로고
    • Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals
    • Shan, M. et al. Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals. Science 342, 447-453 (2013).
    • (2013) Science , vol.342 , pp. 447-453
    • Shan, M.1
  • 28
    • 84981169022 scopus 로고    scopus 로고
    • Immunological aspects of intestinal mucus and mucins
    • Johansson, M.E.V. & Hansson, G.C. Immunological aspects of intestinal mucus and mucins. Nat. Rev. Immunol. 16, 639-649 (2016).
    • (2016) Nat. Rev. Immunol. , vol.16 , pp. 639-649
    • Johansson, M.E.V.1    Hansson, G.C.2
  • 29
    • 33845910419 scopus 로고    scopus 로고
    • Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement
    • Chieppa, M., Rescigno, M., Huang, A.Y.C. & Germain, R.N. Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement. J. Exp. Med. 203, 2841-2852 (2006).
    • (2006) J. Exp. Med. , vol.203 , pp. 2841-2852
    • Chieppa, M.1    Rescigno, M.2    Huang, A.Y.C.3    Germain, R.N.4
  • 30
    • 84875489998 scopus 로고    scopus 로고
    • Luminal bacteria recruit CD103 dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation
    • Farache, J. et al. Luminal bacteria recruit CD103 dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation. Immunity 38, 581-595 (2013).
    • (2013) Immunity , vol.38 , pp. 581-595
    • Farache, J.1
  • 31
    • 84894107663 scopus 로고    scopus 로고
    • Oral tolerance can be established via gap junction transfer of fed antigens from CX3CR1 macrophages to CD103 dendritic cells
    • Mazzini, E.,Massimiliano, L., Penna, G. & Rescigno, M. Oral tolerance can be established via gap junction transfer of fed antigens from CX3CR1 macrophages to CD103 dendritic cells. Immunity 40, 248-261 (2014).
    • (2014) Immunity , vol.40 , pp. 248-261
    • Mazzini, E.1    Massimiliano, L.2    Penna, G.3    Rescigno, M.4
  • 32
    • 0015097333 scopus 로고
    • Peyer's patches: An enriched source of precursors for IgA-producing immunocytes in the rabbit
    • Craig, S.W. & Cebra, J.J. Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit. J. Exp. Med. 134, 188-200 (1971).
    • (1971) J. Exp. Med. , vol.134 , pp. 188-200
    • Craig, S.W.1    Cebra, J.J.2
  • 33
    • 0033583477 scopus 로고    scopus 로고
    • Hapten-induced colitis is associated with colonic patch hypertrophy and T helper cell 2-type responses
    • Dohi, T. et al. Hapten-induced colitis is associated with colonic patch hypertrophy and T helper cell 2-type responses. J. Exp. Med. 189, 1169-1180 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 1169-1180
    • Dohi, T.1
  • 34
    • 0022480493 scopus 로고
    • Lymphoglandular complexes of the colon: Structure and distribution
    • O'Leary, A.D. & Sweeney, E.C. Lymphoglandular complexes of the colon: structure and distribution. Histopathology 10, 267-283 (1986).
    • (1986) Histopathology , vol.10 , pp. 267-283
    • O'Leary, A.D.1    Sweeney, E.C.2
  • 35
    • 77951639699 scopus 로고    scopus 로고
    • Tcell-independent IgA class switch recombination is restricted to the GALTand occurs prior to manifest germinal center formation
    • Bergqvist, P., Stensson, A., Lycke, N.Y. & Bemark, M. Tcell-independent IgA class switch recombination is restricted to the GALTand occurs prior to manifest germinal center formation. J. Immunol. 184, 3545-3553 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 3545-3553
    • Bergqvist, P.1    Stensson, A.2    Lycke, N.Y.3    Bemark, M.4
  • 36
    • 84866689362 scopus 로고    scopus 로고
    • Isolated lymphoid follicles are dynamic reservoirs for the induction of intestinal IgA
    • Knoop, K.A. & Newberry, R.D. Isolated lymphoid follicles are dynamic reservoirs for the induction of intestinal IgA. Front. Immunol. 3, 84 (2012).
    • (2012) Front. Immunol. , vol.3 , pp. 84
    • Knoop, K.A.1    Newberry, R.D.2
  • 37
    • 84876355773 scopus 로고    scopus 로고
    • Colonic patch and colonic SILT development are independent and differentially regulated events
    • Baptista, A.P. et al. Colonic patch and colonic SILT development are independent and differentially regulated events. Mucosal Immunol. 6, 511-521 (2013).
    • (2013) Mucosal Immunol. , vol.6 , pp. 511-521
    • Baptista, A.P.1
  • 38
    • 84856477029 scopus 로고    scopus 로고
    • Induction of gut IgA production through T cell-dependent and T cell-independent pathways
    • Bemark, M., Boysen, P. & Lycke, N.Y. Induction of gut IgA production through T cell-dependent and T cell-independent pathways. Ann. NY Acad. Sci. 1247, 97-116 (2012).
    • (2012) Ann. NY Acad. Sci. , vol.1247 , pp. 97-116
    • Bemark, M.1    Boysen, P.2    Lycke, N.Y.3
  • 39
    • 0037851984 scopus 로고    scopus 로고
    • Isolated lymphoid follicle formation is inducible and dependent upon lymphotoxin-sufficient B lymphocytes, lymphotoxin beta receptor, and TNF receptor i function
    • Lorenz, R.G., Chaplin, D.D., McDonald, K.G., McDonough, J.S. & Newberry, R.D. Isolated lymphoid follicle formation is inducible and dependent upon lymphotoxin-sufficient B lymphocytes, lymphotoxin beta receptor, and TNF receptor I function. J. Immunol. 170, 5475-5482 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 5475-5482
    • Lorenz, R.G.1    Chaplin, D.D.2    McDonald, K.G.3    McDonough, J.S.4    Newberry, R.D.5
  • 40
    • 19944427114 scopus 로고    scopus 로고
    • Cryptopatches and isolated lymphoid follicles: Dynamic lymphoid tissues dispensable for the generation of intraepithelial lymphocytes
    • Pabst, O. et al. Cryptopatches and isolated lymphoid follicles: dynamic lymphoid tissues dispensable for the generation of intraepithelial lymphocytes. Eur. J. Immunol. 35, 98-107 (2005).
    • (2005) Eur. J. Immunol. , vol.35 , pp. 98-107
    • Pabst, O.1
  • 41
    • 84908132881 scopus 로고    scopus 로고
    • Generation of colonic IgA-secreting cells in the caecal patch
    • Masahata, K. et al. Generation of colonic IgA-secreting cells in the caecal patch. Nat. Commun. 5, 3704 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 3704
    • Masahata, K.1
  • 42
    • 84898685253 scopus 로고    scopus 로고
    • Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses
    • Lé cuyer, E. et al. Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses. Immunity 40, 608-620 (2014).
    • (2014) Immunity , vol.40 , pp. 608-620
    • Lé Cuyer, E.1
  • 43
    • 78651500757 scopus 로고    scopus 로고
    • Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells
    • Lochner,M. et al. Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells. J. Exp. Med. 208, 125-134 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 125-134
    • Lochner, M.1
  • 44
    • 75949119878 scopus 로고    scopus 로고
    • Mesenteric lymph nodes are not required for an intestinal immunoglobulin A response to oral cholera toxin
    • Hahn, A., Thiessen, N., Pabst, R., Buettner, M. & Bode, U. Mesenteric lymph nodes are not required for an intestinal immunoglobulin A response to oral cholera toxin. Immunology 129, 427-436 (2010).
    • (2010) Immunology , vol.129 , pp. 427-436
    • Hahn, A.1    Thiessen, N.2    Pabst, R.3    Buettner, M.4    Bode, U.5
  • 45
    • 84870252354 scopus 로고    scopus 로고
    • New concepts in the generation and functions of IgA
    • Pabst, O. New concepts in the generation and functions of IgA. Nat. Rev. Immunol. 12, 821-832 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 821-832
    • Pabst, O.1
  • 46
    • 84859808080 scopus 로고    scopus 로고
    • Oral tolerance to food protein
    • Pabst, O. & Mowat, A.M. Oral tolerance to food protein. Mucosal Immunol. 5, 232-239 (2012).
    • (2012) Mucosal Immunol. , vol.5 , pp. 232-239
    • Pabst, O.1    Mowat, A.M.2
  • 47
    • 84961815094 scopus 로고    scopus 로고
    • The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct
    • Houston, S.A. et al. The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct. Mucosal Immunol. 9, 468-478 (2016).
    • (2016) Mucosal Immunol. , vol.9 , pp. 468-478
    • Houston, S.A.1
  • 49
    • 0035253567 scopus 로고    scopus 로고
    • Protective intestinal anti-rotavirus B cell immunity is dependent on alpha 4 beta 7 integrin expression but does not require IgA antibody production
    • Kuklin, N.A. et al. Protective intestinal anti-rotavirus B cell immunity is dependent on alpha 4 beta 7 integrin expression but does not require IgA antibody production. J. Immunol. 166, 1894-1902 (2001).
    • (2001) J. Immunol. , vol.166 , pp. 1894-1902
    • Kuklin, N.A.1
  • 50
    • 4644236317 scopus 로고    scopus 로고
    • CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells
    • Hieshima, K. et al. CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells. J. Immunol. 173, 3668-3675 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 3668-3675
    • Hieshima, K.1
  • 51
    • 1342300522 scopus 로고    scopus 로고
    • Chemokine receptor CCR9 contributes to the localization of plasma cells to the small intestine
    • Pabst, O. et al. Chemokine receptor CCR9 contributes to the localization of plasma cells to the small intestine. J. Exp. Med. 199, 411-416 (2004).
    • (2004) J. Exp. Med. , vol.199 , pp. 411-416
    • Pabst, O.1
  • 52
    • 33646483489 scopus 로고    scopus 로고
    • Redundant role of chemokines CCL25/TECK and CCL28/ MECin IgA plasmablast recruitment to the intestinal lamina propria after rotavirus infection
    • Feng, N. et al. Redundant role of chemokines CCL25/TECK and CCL28/ MECin IgA plasmablast recruitment to the intestinal lamina propria after rotavirus infection. J. Immunol. 176, 5749-5759 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 5749-5759
    • Feng, N.1
  • 53
    • 0037221029 scopus 로고    scopus 로고
    • Cholera toxin induces migration of dendritic cells from the subepithelial dome region to T-and B-cell areas of Peyer's patches
    • Shreedhar, V.K., Kelsall, B.L. & Neutra, M.R. Cholera toxin induces migration of dendritic cells from the subepithelial dome region to T-and B-cell areas of Peyer's patches. Infect. Immun. 71, 504-509 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 504-509
    • Shreedhar, V.K.1    Kelsall, B.L.2    Neutra, M.R.3
  • 54
    • 84963516373 scopus 로고    scopus 로고
    • Peyer's patches: Organizing B-cell responses at the intestinal frontier
    • Reboldi, A. & Cyster, J.G. Peyer's patches: organizing B-cell responses at the intestinal frontier. Immunol. Rev. 271, 230-245 (2016).
    • (2016) Immunol. Rev. , vol.271 , pp. 230-245
    • Reboldi, A.1    Cyster, J.G.2
  • 55
    • 84969262892 scopus 로고    scopus 로고
    • IgA production requires B cell interaction with subepithelial dendritic cells in Peyer's patches
    • Reboldi, A. et al. IgA production requires B cell interaction with subepithelial dendritic cells in Peyer's patches. Science 352, aaf4822-aaf4822 (2016).
    • (2016) Science , vol.352 , pp. aaf4822-aaf4822
    • Reboldi, A.1
  • 56
    • 34548176272 scopus 로고    scopus 로고
    • Regulation of IgA production by naturally occurring TNF/ iNOS-producing dendritic cells
    • Tezuka, H. et al. Regulation of IgA production by naturally occurring TNF/ iNOS-producing dendritic cells. Nature 448, 929-933 (2007).
    • (2007) Nature , vol.448 , pp. 929-933
    • Tezuka, H.1
  • 57
    • 79951729700 scopus 로고    scopus 로고
    • Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction
    • Tezuka,H. et al. Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction. Immunity 34, 247-257 (2011).
    • (2011) Immunity , vol.34 , pp. 247-257
    • Tezuka, H.1
  • 58
    • 45549099429 scopus 로고    scopus 로고
    • Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
    • Uematsu, S. et al. Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5. Nat. Immunol. 9, 769-776 (2008).
    • (2008) Nat. Immunol. , vol.9 , pp. 769-776
    • Uematsu, S.1
  • 59
    • 33751577786 scopus 로고    scopus 로고
    • Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers
    • Bergqvist, P., Gä rdby, E., Stensson, A., Bemark, M. & Lycke, N.Y. Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers. J. Immunol. 177, 7772-7783 (2006).
    • (2006) J. Immunol. , vol.177 , pp. 7772-7783
    • Bergqvist, P.1    Gä Rdby, E.2    Stensson, A.3    Bemark, M.4    Lycke, N.Y.5
  • 60
    • 2442479518 scopus 로고    scopus 로고
    • IgA class switch occurs in the organized nasopharynxand gut-associated lymphoid tissue, but not in the diffuse lamina propria of airways and gut
    • Shikina, T. et al. IgA class switch occurs in the organized nasopharynxand gut-associated lymphoid tissue, but not in the diffuse lamina propria of airways and gut. J. Immunol. 172, 6259-6264 (2004).
    • (2004) J. Immunol. , vol.172 , pp. 6259-6264
    • Shikina, T.1
  • 61
    • 0035846113 scopus 로고    scopus 로고
    • In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
    • Fagarasan, S., Kinoshita, K., Muramatsu, M., Ikuta, K. & Honjo, T. In situ class switching and differentiation to IgA-producing cells in the gut lamina propria. Nature 413, 639-643 (2001).
    • (2001) Nature , vol.413 , pp. 639-643
    • Fagarasan, S.1    Kinoshita, K.2    Muramatsu, M.3    Ikuta, K.4    Honjo, T.5
  • 62
    • 34250205694 scopus 로고    scopus 로고
    • Intestinal bacteria trigger Tcell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine April
    • He, B. et al. Intestinal bacteria trigger Tcell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity 26, 812-826 (2007).
    • (2007) Immunity , vol.26 , pp. 812-826
    • He, B.1
  • 63
    • 20444498902 scopus 로고    scopus 로고
    • Human intestinal IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria
    • Boursier, L., Gordon, J.N., Thiagamoorthy, S., Edgeworth, J.D. & Spencer, J. Human intestinal IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria. Gastroenterology 128, 1879-1889 (2005).
    • (2005) Gastroenterology , vol.128 , pp. 1879-1889
    • Boursier, L.1    Gordon, J.N.2    Thiagamoorthy, S.3    Edgeworth, J.D.4    Spencer, J.5
  • 64
    • 39149098145 scopus 로고    scopus 로고
    • Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney
    • Shen, H.M. et al. Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney. Mol. Immunol. 45, 1883-1892 (2008).
    • (2008) Mol. Immunol. , vol.45 , pp. 1883-1892
    • Shen, H.M.1
  • 65
    • 4043108358 scopus 로고    scopus 로고
    • Divide and conquer: The importance of cell division in regulating B-cell responses
    • Tangye, S.G. & Hodgkin, P.D. Divide and conquer: the importance of cell division in regulating B-cell responses. Immunology 112, 509-520 (2004).
    • (2004) Immunology , vol.112 , pp. 509-520
    • Tangye, S.G.1    Hodgkin, P.D.2
  • 66
    • 0035940511 scopus 로고    scopus 로고
    • A hallmark of active class switch recombination: Transcripts directed by i promoters on looped-out circular DNAs
    • Kinoshita, K., Harigai, M., Fagarasan, S., Muramatsu, M. & Honjo, T. A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs. Proc. Natl Acad. Sci. USA 98, 12620-12623 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 12620-12623
    • Kinoshita, K.1    Harigai, M.2    Fagarasan, S.3    Muramatsu, M.4    Honjo, T.5
  • 67
    • 34249108271 scopus 로고    scopus 로고
    • Regulation of AID expression in the immune response
    • Crouch, E.E. et al. Regulation of AID expression in the immune response. J. Exp. Med. 204, 1145-1156 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 1145-1156
    • Crouch, E.E.1
  • 68
    • 77952311371 scopus 로고    scopus 로고
    • Adaptive immune regulation in the gut: Tcell-dependent and Tcell-independent IgA synthesis
    • Fagarasan, S., Kawamoto, S., Kanagawa, O. & Suzuki, K. Adaptive immune regulation in the gut: Tcell-dependent and Tcell-independent IgA synthesis. Annu. Rev. Immunol. 28, 243-273 (2010).
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 243-273
    • Fagarasan, S.1    Kawamoto, S.2    Kanagawa, O.3    Suzuki, K.4
  • 69
    • 3142740243 scopus 로고    scopus 로고
    • Role of gut-associated lymphoreticular tissues in antigen-specific intestinal IgA immunity
    • Yamamoto, M. et al. Role of gut-associated lymphoreticular tissues in antigen-specific intestinal IgA immunity. J. Immunol. 173, 762-769 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 762-769
    • Yamamoto, M.1
  • 70
    • 0018116086 scopus 로고
    • The origin and antigen-dependent distribution of IgA-containing cells in the intestine
    • Husband, A.J. & Gowans, J.L. The origin and antigen-dependent distribution of IgA-containing cells in the intestine. J. Exp. Med. 148, 1146-1160 (1978).
    • (1978) J. Exp. Med. , vol.148 , pp. 1146-1160
    • Husband, A.J.1    Gowans, J.L.2
  • 71
    • 84986568270 scopus 로고    scopus 로고
    • Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization
    • Bemark, M. et al. Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization. Nat. Commun. 7, 12698 (2016).
    • (2016) Nat. Commun. , vol.7 , pp. 12698
    • Bemark, M.1
  • 72
    • 84874218199 scopus 로고    scopus 로고
    • The role of Peyer's patches in synchronizing gut IgA responses
    • Lycke, N.Y. & Bemark, M. The role of Peyer's patches in synchronizing gut IgA responses. Front. Immunol. 3, 329 (2012).
    • (2012) Front. Immunol. , vol.3 , pp. 329
    • Lycke, N.Y.1    Bemark, M.2
  • 73
    • 70249085594 scopus 로고    scopus 로고
    • Memory B cells: Effectors of long-lived immune responses
    • Tangye, S. & Tarlinton, D. Memory B cells: effectors of long-lived immune responses. Eur. J. Immunol. 39, 2065-2075 (2009).
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2065-2075
    • Tangye, S.1    Tarlinton, D.2
  • 74
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty, S. Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 29, 621-663 (2011).
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 621-663
    • Crotty, S.1
  • 76
    • 78149477766 scopus 로고    scopus 로고
    • Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter
    • Victora, G.D. et al. Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell 143, 592-605 (2010).
    • (2010) Cell , vol.143 , pp. 592-605
    • Victora, G.D.1
  • 77
    • 84961156088 scopus 로고    scopus 로고
    • Visualizing antibody affinity maturation in germinal centers
    • Tas, J.M.J. et al. Visualizing antibody affinity maturation in germinal centers. Science 351, 1048-1054 (2016).
    • (2016) Science , vol.351 , pp. 1048-1054
    • Tas, J.M.J.1
  • 78
    • 84903387500 scopus 로고    scopus 로고
    • Follicular dendritic cells: Dynamic antigen libraries
    • Heesters, B.A., Myers, R.C. & Carroll, M.C. Follicular dendritic cells: dynamic antigen libraries. Nat. Rev. Immunol. 14, 495-504 (2014).
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 495-504
    • Heesters, B.A.1    Myers, R.C.2    Carroll, M.C.3
  • 80
    • 1542377328 scopus 로고    scopus 로고
    • B cell receptor signal strength determines B cell fate
    • Casola, S. et al. B cell receptor signal strength determines B cell fate. Nat. Immunol. 5, 317-327 (2004).
    • (2004) Nat. Immunol. , vol.5 , pp. 317-327
    • Casola, S.1
  • 82
    • 48749091530 scopus 로고    scopus 로고
    • Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut
    • Tsuji, M. et al. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity 29, 261-271 (2008).
    • (2008) Immunity , vol.29 , pp. 261-271
    • Tsuji, M.1
  • 83
    • 34249790004 scopus 로고    scopus 로고
    • Molecular mechanisms of antibody somatic hypermutation
    • Di Noia, J.M. & Neuberger, M.S. Molecular mechanisms of antibody somatic hypermutation. Annu. Rev. Biochem. 76, 1-22 (2007).
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 1-22
    • Di Noia, J.M.1    Neuberger, M.S.2
  • 84
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu, M. et al. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102, 553-563 (2000).
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1
  • 85
    • 0033603340 scopus 로고    scopus 로고
    • Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
    • Muramatsu, M. et al. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J. Biol. Chem. 274, 18470-18476 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 18470-18476
    • Muramatsu, M.1
  • 86
    • 84856872027 scopus 로고    scopus 로고
    • Age, microbiota, and Tcells shape diverse individual IgA repertoires in the intestine
    • Lindner, C. et al. Age, microbiota, and Tcells shape diverse individual IgA repertoires in the intestine. J. Exp. Med. 209, 365-377 (2012).
    • (2012) J. Exp. Med. , vol.209 , pp. 365-377
    • Lindner, C.1
  • 87
    • 85007605886 scopus 로고    scopus 로고
    • Single-cell analysis of the plasmablast response to vibrio cholerae demonstrates expansion of cross-reactive memory B cells
    • Kauffman, R.C. et al. Single-cell analysis of the plasmablast response to vibrio cholerae demonstrates expansion of cross-reactive memory B cells. MBio 7, e02021-16 (2016).
    • (2016) MBio , vol.7 , pp. e02021-e02116
    • Kauffman, R.C.1
  • 88
    • 84912535553 scopus 로고    scopus 로고
    • IgH chain class switch recombination: Mechanism and regulation
    • Stavnezer, J. & Schrader, C.E. IgH chain class switch recombination: mechanism and regulation. J. Immunol. 193, 5370-5378 (2014).
    • (2014) J. Immunol. , vol.193 , pp. 5370-5378
    • Stavnezer, J.1    Schrader, C.E.2
  • 90
    • 59849123627 scopus 로고    scopus 로고
    • The surprising discovery that TGF beta specifically induces the IgA class switch
    • Stavnezer, J. & Kang, J. The surprising discovery that TGF beta specifically induces the IgA class switch. J. Immunol. 182, 5-7 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 5-7
    • Stavnezer, J.1    Kang, J.2
  • 91
    • 0033697670 scopus 로고    scopus 로고
    • TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo
    • Cazac, B.B. & Roes, J. TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo. Immunity 13, 443-451 (2000).
    • (2000) Immunity , vol.13 , pp. 443-451
    • Cazac, B.B.1    Roes, J.2
  • 92
    • 4344623276 scopus 로고    scopus 로고
    • TGF-beta receptor signaling is critical for mucosal IgA responses
    • Borsutzky, S., Cazac, B.B., Roes, J. & Guzman, C.A. TGF-beta receptor signaling is critical for mucosal IgA responses. J. Immunol. 173, 3305-3309 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 3305-3309
    • Borsutzky, S.1    Cazac, B.B.2    Roes, J.3    Guzman, C.A.4
  • 93
    • 84896973126 scopus 로고    scopus 로고
    • TGF-B activation and function in immunity
    • Travis, M.A. & Sheppard, D. TGF-b Activation and Function in Immunity. Annu. Rev. Immunol. 32, 51-82 (2014).
    • (2014) Annu. Rev. Immunol. , vol.32 , pp. 51-82
    • Travis, M.A.1    Sheppard, D.2
  • 94
    • 33751223544 scopus 로고    scopus 로고
    • Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
    • Mora, J.R. et al. Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells. Science 314, 1157-1160 (2006).
    • (2006) Science , vol.314 , pp. 1157-1160
    • Mora, J.R.1
  • 95
    • 62449202866 scopus 로고    scopus 로고
    • Preferential generation of follicular B helper T cells from Foxp3 Tcells in gut Peyer's patches
    • Tsuji, M. et al. Preferential generation of follicular B helper T cells from Foxp3 Tcells in gut Peyer's patches. Science 323, 1488-1492 (2009).
    • (2009) Science , vol.323 , pp. 1488-1492
    • Tsuji, M.1
  • 96
    • 12344297875 scopus 로고    scopus 로고
    • TACI and BAFF-R mediate isotype switching in B cells
    • Castigli, E. et al. TACI and BAFF-R mediate isotype switching in B cells. J. Exp. Med. 201, 35-39 (2005).
    • (2005) J. Exp. Med. , vol.201 , pp. 35-39
    • Castigli, E.1
  • 97
    • 27844541797 scopus 로고    scopus 로고
    • Control of B-cell responses by Toll-like receptors
    • Pasare, C. & Medzhitov, R. Control of B-cell responses by Toll-like receptors. Nature 438, 364-368 (2005).
    • (2005) Nature , vol.438 , pp. 364-368
    • Pasare, C.1    Medzhitov, R.2
  • 98
    • 0035004320 scopus 로고    scopus 로고
    • Regulation of the T-independent humoral response by TACI
    • von Bü low, G.U., van Deursen, J.M. & Bram, R.J. Regulation of the T-independent humoral response by TACI. Immunity 14, 573-582 (2001).
    • (2001) Immunity , vol.14 , pp. 573-582
    • Von Bü Low, G.U.1    Van Deursen, J.M.2    Bram, R.J.3
  • 99
    • 0034919939 scopus 로고    scopus 로고
    • Activation and accumulation of B cells in TACI-deficient mice
    • Yan, M. et al. Activation and accumulation of B cells in TACI-deficient mice. Nat. Immunol. 2, 638-643 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 638-643
    • Yan, M.1
  • 100
    • 9144244788 scopus 로고    scopus 로고
    • April-deficient mice have normal immune system development
    • Varfolomeev, E. et al. APRIL-deficient mice have normal immune system development. Mol. Cell. Biol. 24, 997-1006 (2004).
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 997-1006
    • Varfolomeev, E.1
  • 101
    • 1642332951 scopus 로고    scopus 로고
    • Impaired IgA class switching in April-deficient mice
    • Castigli, E. et al. Impaired IgA class switching in APRIL-deficient mice. Proc. Natl Acad. Sci. USA 101, 3903-3908 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 3903-3908
    • Castigli, E.1
  • 102
    • 80054875478 scopus 로고    scopus 로고
    • Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease
    • Rickert, R.C., Jellusova, J. & Miletic, A.V. Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease. Immunol. Rev. 244, 115-133 (2011).
    • (2011) Immunol. Rev. , vol.244 , pp. 115-133
    • Rickert, R.C.1    Jellusova, J.2    Miletic, A.V.3
  • 103
    • 56249112586 scopus 로고    scopus 로고
    • Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells
    • Mora, J.R. & von Andrian, U.H. Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells. Semin. Immunol. 21, 28-35 (2009).
    • (2009) Semin. Immunol. , vol.21 , pp. 28-35
    • Mora, J.R.1    Von Andrian, U.H.2
  • 104
    • 79954498391 scopus 로고    scopus 로고
    • Retinoic acid induces expression of Ig germ line a transcript, an IgA isotype switching indicative, through retinoic acid receptor
    • Park, M.-H., Park, S.-R., Lee, M.-R., Kim, Y.-H. & Kim, P.-H. Retinoic acid induces expression of Ig germ line a transcript, an IgA isotype switching indicative, through retinoic acid receptor. Genes Genome 33, 83-88 (2011).
    • (2011) Genes Genome , vol.33 , pp. 83-88
    • Park, M.-H.1    Park, S.-R.2    Lee, M.-R.3    Kim, Y.-H.4    Kim, P.-H.5
  • 105
    • 80051925343 scopus 로고    scopus 로고
    • Vitamin A deficiency impairs vaccine-elicited gastrointestinal immunity
    • Kaufman, D.R. et al. Vitamin A deficiency impairs vaccine-elicited gastrointestinal immunity. J. Immunol. 187, 1877-1883 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 1877-1883
    • Kaufman, D.R.1
  • 106
    • 84939501634 scopus 로고    scopus 로고
    • Interleukin (IL)-21 promotes intestinal IgA response to microbiota
    • Cao, A.T. et al. Interleukin (IL)-21 promotes intestinal IgA response to microbiota. Mucosal Immunol. 8, 1072-1082 (2015).
    • (2015) Mucosal Immunol. , vol.8 , pp. 1072-1082
    • Cao, A.T.1
  • 107
    • 33847412873 scopus 로고    scopus 로고
    • IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo
    • Frö hlich, A. et al. IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo. Blood 109, 2023-2031 (2007).
    • (2007) Blood , vol.109 , pp. 2023-2031
    • Frö Hlich, A.1
  • 108
    • 84867908677 scopus 로고    scopus 로고
    • Th17 cells upregulate polymeric Ig receptor and intestinal IgA and contribute to intestinal homeostasis
    • Cao, A.T., Yao, S.,Gong, B., Elson, C.O. & Cong, Y. Th17 cells upregulate polymeric Ig receptor and intestinal IgA and contribute to intestinal homeostasis. J. Immunol. 189, 4666-4673 (2012).
    • (2012) J. Immunol. , vol.189 , pp. 4666-4673
    • Cao, A.T.1    Yao, S.2    Gong, B.3    Elson, C.O.4    Cong, Y.5
  • 109
    • 77953768395 scopus 로고    scopus 로고
    • Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthrax
    • Datta, S.K. et al. Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthrax. Proc. Natl Acad. Sci. USA 107, 10638-10643 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 10638-10643
    • Datta, S.K.1
  • 110
    • 65549098748 scopus 로고    scopus 로고
    • IL-21 ensures TGF-beta 1-induced IgA isotype expression inmouse Peyer's patches
    • Seo, G.-Y., Youn, J. & Kim, P.-H. IL-21 ensures TGF-beta 1-induced IgA isotype expression inmouse Peyer's patches. J. Leukoc. Biol. 85, 744-750 (2009).
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 744-750
    • Seo, G.-Y.1    Youn, J.2    Kim, P.-H.3
  • 111
    • 77954898661 scopus 로고    scopus 로고
    • The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut
    • Suzuki, K. et al. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity 33, 71-83 (2010).
    • (2010) Immunity , vol.33 , pp. 71-83
    • Suzuki, K.1
  • 112
    • 84864331772 scopus 로고    scopus 로고
    • Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal, and affinity-matured gut IgA responses
    • Bergqvist, P. et al. Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal, and affinity-matured gut IgA responses. Mucosal Immunol. 6, 122-135 (2013).
    • (2013) Mucosal Immunol. , vol.6 , pp. 122-135
    • Bergqvist, P.1
  • 113
    • 84957677798 scopus 로고    scopus 로고
    • Regulation of germinal center B-cell differentiation
    • Zhang, Y., Garcia-Ibanez, L. & Toellner, K.-M. Regulation of germinal center B-cell differentiation. Immunol. Rev. 270, 8-19 (2016).
    • (2016) Immunol. Rev. , vol.270 , pp. 8-19
    • Zhang, Y.1    Garcia-Ibanez, L.2    Toellner, K.-M.3
  • 114
    • 80054902426 scopus 로고    scopus 로고
    • Structure and function relationships in IgA
    • Woof, J.M. & Russell, M.W. Structure and function relationships in IgA. Mucosal Immunol. 4, 590-597 (2011).
    • (2011) Mucosal Immunol. , vol.4 , pp. 590-597
    • Woof, J.M.1    Russell, M.W.2
  • 115
    • 84912032793 scopus 로고    scopus 로고
    • Increased serum IgA in Fca/ mR-deficient mice on the (129 x C57BL/6) F1 genetic background
    • Kurita, N., Honda, S.-I. & Shibuya, A. Increased serum IgA in Fca/ mR-deficient mice on the (129 x C57BL/6) F1 genetic background. Mol. Immunol. 63, 367-372 (2015).
    • (2015) Mol. Immunol. , vol.63 , pp. 367-372
    • Kurita, N.1    Honda, S.-I.2    Shibuya, A.3
  • 116
    • 84877614313 scopus 로고    scopus 로고
    • Germinal center B cells govern their own fate via antibody feedback
    • Zhang, Y. et al. Germinal center B cells govern their own fate via antibody feedback. J. Exp. Med. 210, 457-464 (2013).
    • (2013) J. Exp. Med. , vol.210 , pp. 457-464
    • Zhang, Y.1
  • 117
    • 85014614174 scopus 로고    scopus 로고
    • Cutting edge: Ll-37-mediated formyl peptide receptor-2 signaling in follicular dendritic cells contributes to b cell activation in peyer's patch germinal centers
    • Kim, S.-H., Kim, Y.N. & Jang, Y.-S.Cutting Edge: LL-37-Mediated Formyl Peptide Receptor-2 Signaling in Follicular Dendritic Cells Contributes to B Cell Activation in Peyer's Patch Germinal Centers. J. Immunol. 198, 629-633 (2017).
    • (2017) J. Immunol. , vol.198 , pp. 629-633
    • Kim, S.-H.1    Kim, Y.N.2    Jang, Y.-S.3
  • 118
    • 84902591469 scopus 로고    scopus 로고
    • Follicular dendritic cell secreted protein FDC-SP controls IgA production
    • Hou, S. et al. Follicular dendritic cell secreted protein FDC-SP controls IgA production. Mucosal Immunol. 7, 948-957 (2014).
    • (2014) Mucosal Immunol. , vol.7 , pp. 948-957
    • Hou, S.1
  • 119
    • 48549103766 scopus 로고    scopus 로고
    • Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria
    • Shang, L. et al. Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. Gastroenterology 135, 529-538 (2008).
    • (2008) Gastroenterology , vol.135 , pp. 529-538
    • Shang, L.1
  • 120
    • 84871925567 scopus 로고    scopus 로고
    • CD226 interactionwith CD155 impacts on retention and negative selection of CD8 positive thymocytes as well as T cell differentiation to follicular helper cells in Peyer's Patches
    • Danisch, S. et al. CD226 interactionwith CD155 impacts on retention and negative selection of CD8 positive thymocytes as well as T cell differentiation to follicular helper cells in Peyer's Patches. Immunobiology 218, 152-158 (2013).
    • (2013) Immunobiology , vol.218 , pp. 152-158
    • Danisch, S.1
  • 121
    • 80955158378 scopus 로고    scopus 로고
    • Näve CD4 T cells of Peyer's patches produce more IL-6 than those of spleen in response to antigenic stimulation
    • Hashiguchi, M. et al. Näve CD4 T cells of Peyer's patches produce more IL-6 than those of spleen in response to antigenic stimulation. Immunol. Lett. 141, 109-115 (2011).
    • (2011) Immunol. Lett. , vol.141 , pp. 109-115
    • Hashiguchi, M.1
  • 122
    • 70449350384 scopus 로고    scopus 로고
    • Abundance of follicular helper T cells in Peyer's patches is modulated by CD155
    • Seth, S. et al. Abundance of follicular helper T cells in Peyer's patches is modulated by CD155. Eur. J. Immunol. 39, 3160-3170 (2009).
    • (2009) Eur. J. Immunol. , vol.39 , pp. 3160-3170
    • Seth, S.1
  • 123
    • 84964644988 scopus 로고    scopus 로고
    • T follicular helper cells, T follicular regulatory cells and autoimmunity
    • Zhu, Y., Zou, L. & Liu, Y.-C. T follicular helper cells, T follicular regulatory cells and autoimmunity. Int. Immunol. 28, 173-179 (2016).
    • (2016) Int. Immunol. , vol.28 , pp. 173-179
    • Zhu, Y.1    Zou, L.2    Liu, Y.-C.3
  • 124
    • 84907272327 scopus 로고    scopus 로고
    • Dynamic signaling by T follicular helper cells during germinal center B cell selection
    • Shulman, Z. et al. Dynamic signaling by T follicular helper cells during germinal center B cell selection. Science 345, 1058-1062 (2014).
    • (2014) Science , vol.345 , pp. 1058-1062
    • Shulman, Z.1
  • 125
    • 0026772133 scopus 로고
    • A 39-kDa protein on activated helper Tcells binds CD40 and transduces the signal for cognate activation of B cells
    • Noelle, R.J. et al. A 39-kDa protein on activated helper Tcells binds CD40 and transduces the signal for cognate activation of B cells. Proc. Natl Acad. Sci. USA 89, 6550-6554 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 6550-6554
    • Noelle, R.J.1
  • 127
    • 84963593799 scopus 로고    scopus 로고
    • T follicular regulatory cells
    • Sage, P.T. & Sharpe, A.H. T follicular regulatory cells. Immunol. Rev. 271, 246-259 (2016).
    • (2016) Immunol. Rev. , vol.271 , pp. 246-259
    • Sage, P.T.1    Sharpe, A.H.2
  • 128
    • 84904384753 scopus 로고    scopus 로고
    • Foxp3() Tcells regulate immunoglobulin a selection and facilitate diversification of bacterial species responsible for immune homeostasis
    • Kawamoto, S. et al. Foxp3() Tcells regulate immunoglobulin a selection and facilitate diversification of bacterial species responsible for immune homeostasis. Immunity 41, 152-165 (2014).
    • (2014) Immunity , vol.41 , pp. 152-165
    • Kawamoto, S.1
  • 129
    • 84961373922 scopus 로고    scopus 로고
    • Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive Tcells
    • Aloulou, M. et al. Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive Tcells. Nat. Commun. 7, 10579 (2016).
    • (2016) Nat. Commun. , vol.7 , pp. 10579
    • Aloulou, M.1
  • 130
    • 85020743755 scopus 로고    scopus 로고
    • Stat3 is important for follicular regulatory t cell differentiation
    • Wu, H., Xie, M.M., Liu, H. & Dent, A.L. Stat3 Is Important for Follicular Regulatory T Cell Differentiation. PLoS ONE 11, e0155040 (2016).
    • (2016) PLoS ONE , vol.11 , pp. e0155040
    • Wu, H.1    Xie, M.M.2    Liu, H.3    Dent, A.L.4
  • 131
    • 84989920641 scopus 로고    scopus 로고
    • Suppression by TFR cells leads to durable and selective inhibition of B cell effector function
    • Sage, P.T. et al. Suppression by TFR cells leads to durable and selective inhibition of B cell effector function. Nat. Immunol. 17, 1436-1446 (2016).
    • (2016) Nat. Immunol. , vol.17 , pp. 1436-1446
    • Sage, P.T.1
  • 132
    • 84860123211 scopus 로고    scopus 로고
    • The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut
    • Kawamoto, S. et al. The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science 336, 485-489 (2012).
    • (2012) Science , vol.336 , pp. 485-489
    • Kawamoto, S.1
  • 133
    • 84875473675 scopus 로고    scopus 로고
    • Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses
    • Hirota, K. et al. Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses. Nat. Immunol. 14, 372-379 (2013).
    • (2013) Nat. Immunol. , vol.14 , pp. 372-379
    • Hirota, K.1
  • 135
    • 73349099737 scopus 로고    scopus 로고
    • A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota
    • Cong, Y., Feng, T., Fujihashi, K., Schoeb, T.R. & Elson, C.O. A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota. Proc. Natl Acad. Sci. USA 106, 19256-19261 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 19256-19261
    • Cong, Y.1    Feng, T.2    Fujihashi, K.3    Schoeb, T.R.4    Elson, C.O.5
  • 136
    • 77957838251 scopus 로고    scopus 로고
    • Polyclonal Treg cells enhance the activity of a mucosal adjuvant
    • Vendetti, S. et al. Polyclonal Treg cells enhance the activity of a mucosal adjuvant. Immunol. Cell Biol. 88, 698-706 (2010).
    • (2010) Immunol. Cell Biol. , vol.88 , pp. 698-706
    • Vendetti, S.1
  • 137
    • 84896510761 scopus 로고    scopus 로고
    • FoxP3 regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability
    • Leo N., B., Bradley, J.E., Lund, F.E., Randall, T.D. & Ballesteros-Tato, A. FoxP3 regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability. Nat. Commun. 5, 3495 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 3495
    • Leo, N.B.1    Bradley, J.E.2    Lund, F.E.3    Randall, T.D.4    Ballesteros-Tato, A.5
  • 138
    • 84861423126 scopus 로고    scopus 로고
    • Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation
    • Ballesteros-Tato, A. et al. Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation. Immunity 36, 847-856 (2012).
    • (2012) Immunity , vol.36 , pp. 847-856
    • Ballesteros-Tato, A.1
  • 139
    • 84863116170 scopus 로고    scopus 로고
    • STAT5 is a potent negative regulator of TFH cell differentiation
    • Johnston, R.J., Choi, Y.S.,Diamond, J.A., Yang, J.A. & Crotty, S. STAT5 is a potent negative regulator of TFH cell differentiation. J. Exp. Med. 209, 243-250 (2012).
    • (2012) J. Exp. Med. , vol.209 , pp. 243-250
    • Johnston, R.J.1    Choi, Y.S.2    Diamond, J.A.3    Yang, J.A.4    Crotty, S.5
  • 140
    • 84858706847 scopus 로고    scopus 로고
    • Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
    • Oestreich, K.J., Mohn, S.E. & Weinmann, A.S. Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat. Immunol. 13, 405-411 (2012).
    • (2012) Nat. Immunol. , vol.13 , pp. 405-411
    • Oestreich, K.J.1    Mohn, S.E.2    Weinmann, A.S.3
  • 141
    • 84918575122 scopus 로고    scopus 로고
    • Resident CD4 T cells accumulate in lymphoid organs after prolonged antigen exposure
    • Ugur, M., Schulz, O., Menon, M.B., Krueger, A. & Pabst, O. Resident CD4 T cells accumulate in lymphoid organs after prolonged antigen exposure. Nat. Commun. 5, 4821 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 4821
    • Ugur, M.1    Schulz, O.2    Menon, M.B.3    Krueger, A.4    Pabst, O.5
  • 142
    • 84953305702 scopus 로고    scopus 로고
    • Long-lived plasma cells are generated in mucosal immune responses and contribute to the bone marrow plasma cell pool in mice
    • Lemke, A. et al. Long-lived plasma cells are generated in mucosal immune responses and contribute to the bone marrow plasma cell pool in mice. Mucosal Immunol. 9, 83-97 (2016).
    • (2016) Mucosal Immunol. , vol.9 , pp. 83-97
    • Lemke, A.1
  • 143
    • 84898681828 scopus 로고    scopus 로고
    • Eosinophils promote generation and maintenance of immunoglobulin a expressing plasma cells and contribute to gut immune homeostasis
    • Chu, V.T. et al. Eosinophils promote generation and maintenance of immunoglobulin-a-expressing plasma cells and contribute to gut immune homeostasis. Immunity 40, 582-593 (2014).
    • (2014) Immunity , vol.40 , pp. 582-593
    • Chu, V.T.1
  • 144
    • 84928896887 scopus 로고    scopus 로고
    • IL-1b in eosinophil-mediated small intestinal homeostasis and IgA production
    • Jung, Y. et al. IL-1b in eosinophil-mediated small intestinal homeostasis and IgA production. Mucosal Immunol. 8, 930-942 (2015).
    • (2015) Mucosal Immunol. , vol.8 , pp. 930-942
    • Jung, Y.1
  • 145
    • 84955407770 scopus 로고    scopus 로고
    • Eosinophils: Important players in humoral immunity
    • Berek, C. Eosinophils: important players in humoral immunity. Clin. Exp. Immunol. 183, 57-64 (2016).
    • (2016) Clin. Exp. Immunol. , vol.183 , pp. 57-64
    • Berek, C.1
  • 146
    • 84957620876 scopus 로고    scopus 로고
    • Fostering of advanced mutualism with gut microbiota by Immunoglobulin A
    • Sutherland, D.B., Suzuki, K. & Fagarasan, S. Fostering of advanced mutualism with gut microbiota by Immunoglobulin A. Immunol. Rev. 270, 20-31 (2016).
    • (2016) Immunol. Rev. , vol.270 , pp. 20-31
    • Sutherland, D.B.1    Suzuki, K.2    Fagarasan, S.3
  • 147
    • 0024800242 scopus 로고
    • Serum immunoglobulin levels and naturally occurring antibodies against carbohydrate antigens in germ-free BALB/c mice fed chemically defined ultrafiltered diet
    • Bos, N.A. et al. Serum immunoglobulin levels and naturally occurring antibodies against carbohydrate antigens in germ-free BALB/c mice fed chemically defined ultrafiltered diet. Eur. J. Immunol. 19, 2335-2339 (1989).
    • (1989) Eur. J. Immunol. , vol.19 , pp. 2335-2339
    • Bos, N.A.1
  • 148
    • 0033004028 scopus 로고    scopus 로고
    • Segmented filamentous bacteria are potent stimuli of a physiologically normal state of the murine gutmucosal immune system
    • Talham, G.L., Jiang, H.Q., Bos, N.A. & Cebra, J.J. Segmented filamentous bacteria are potent stimuli of a physiologically normal state of the murine gutmucosal immune system. Infect. Immun. 67, 1992-2000 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 1992-2000
    • Talham, G.L.1    Jiang, H.Q.2    Bos, N.A.3    Cebra, J.J.4
  • 149
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • Ivanov, I.I. et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 139, 485-498 (2009).
    • (2009) Cell , vol.139 , pp. 485-498
    • Ivanov, I.I.1
  • 150
    • 70349742524 scopus 로고    scopus 로고
    • The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses
    • Gaboriau-Routhiau, V. et al. The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses. Immunity 31, 677-689 (2009).
    • (2009) Immunity , vol.31 , pp. 677-689
    • Gaboriau-Routhiau, V.1
  • 151
    • 84926360580 scopus 로고    scopus 로고
    • Growth and host interaction of mouse segmented filamentous bacteria in vitro
    • Schnupf, P. et al. Growth and host interaction of mouse segmented filamentous bacteria in vitro. Nature 520, 99-103 (2015).
    • (2015) Nature , vol.520 , pp. 99-103
    • Schnupf, P.1
  • 152
    • 77952208123 scopus 로고    scopus 로고
    • Indigenous opportunistic bacteria inhabit mammalian gutassociated lymphoid tissues and share a mucosal antibody-mediated symbiosis
    • Obata, T. et al. Indigenous opportunistic bacteria inhabit mammalian gutassociated lymphoid tissues and share a mucosal antibody-mediated symbiosis. Proc. Natl. Acad. Sci. USA 107, 7419-7424 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 7419-7424
    • Obata, T.1
  • 153
    • 77954051526 scopus 로고    scopus 로고
    • Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses
    • Hapfelmeier, S. et al. Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses. Science 328, 1705-1709 (2010).
    • (2010) Science , vol.328 , pp. 1705-1709
    • Hapfelmeier, S.1
  • 154
    • 84920929686 scopus 로고    scopus 로고
    • An enteric virus can replace the beneficial function of commensal bacteria
    • Kernbauer, E., Ding, Y. & Cadwell, K. An enteric virus can replace the beneficial function of commensal bacteria. Nature 516, 94-98 (2014).
    • (2014) Nature , vol.516 , pp. 94-98
    • Kernbauer, E.1    Ding, Y.2    Cadwell, K.3
  • 155
    • 84979735744 scopus 로고    scopus 로고
    • Gut microbial metabolites fuel host antibody responses
    • Kim, M., Qie, Y., Park, J. & Kim, C.H. Gut Microbial Metabolites Fuel Host Antibody Responses. Cell Host Microbe 20, 202-214 (2016).
    • (2016) Cell Host Microbe , vol.20 , pp. 202-214
    • Kim, M.1    Qie, Y.2    Park, J.3    Kim, C.H.4
  • 156
    • 0034705397 scopus 로고    scopus 로고
    • A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria
    • Macpherson, A.J. et al. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 288, 2222-2226 (2000).
    • (2000) Science , vol.288 , pp. 2222-2226
    • Macpherson, A.J.1
  • 157
    • 1542618118 scopus 로고    scopus 로고
    • Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria
    • Macpherson, A.J. & Uhr, T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 303, 1662-1665 (2004).
    • (2004) Science , vol.303 , pp. 1662-1665
    • Macpherson, A.J.1    Uhr, T.2
  • 158
    • 84941659588 scopus 로고    scopus 로고
    • Innate and adaptive humoral responses coat distinct commensal bacteria with immunoglobulin a
    • Bunker, J.J. et al. Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A. Immunity 43, 541-553 (2015).
    • (2015) Immunity , vol.43 , pp. 541-553
    • Bunker, J.J.1
  • 159
    • 84907300008 scopus 로고    scopus 로고
    • Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease
    • Palm, N.W. et al. Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease. Cell 158, 1000-1010 (2014).
    • (2014) Cell , vol.158 , pp. 1000-1010
    • Palm, N.W.1
  • 160
    • 1242296822 scopus 로고    scopus 로고
    • Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
    • Suzuki, K. et al. Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut. Proc. Natl Acad. Sci. USA 101, 1981-1986 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 1981-1986
    • Suzuki, K.1
  • 161
    • 79951602552 scopus 로고    scopus 로고
    • Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense
    • Wei, M. et al. Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense. Nat. Immunol. 12, 264-270 (2011).
    • (2011) Nat. Immunol. , vol.12 , pp. 264-270
    • Wei, M.1
  • 162
    • 84896884079 scopus 로고    scopus 로고
    • Secretory antibodies in breast milk promote long-term intestinal homeostasis by regulating the gut microbiota and host gene expression
    • Rogier, E.W. et al. Secretory antibodies in breast milk promote long-term intestinal homeostasis by regulating the gut microbiota and host gene expression. Proc. Natl Acad. Sci. USA 111, 3074-3079 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 3074-3079
    • Rogier, E.W.1
  • 163
  • 164
    • 0028944944 scopus 로고
    • Early appearance of 'natural' mucosal IgA responses and germinal centers in suckling mice developing in the absence of maternal antibodies
    • Kramer, D.R. & Cebra, J.J. Early appearance of 'natural' mucosal IgA responses and germinal centers in suckling mice developing in the absence of maternal antibodies. J. Immunol. 154, 2051-2062 (1995).
    • (1995) J. Immunol. , vol.154 , pp. 2051-2062
    • Kramer, D.R.1    Cebra, J.J.2
  • 165
    • 33750343043 scopus 로고    scopus 로고
    • Mechanisms of neonatal mucosal antibody protection
    • Harris, N.L. et al. Mechanisms of neonatal mucosal antibody protection. J. Immunol. 177, 6256-6262 (2006).
    • (2006) J. Immunol. , vol.177 , pp. 6256-6262
    • Harris, N.L.1
  • 166
    • 84991929179 scopus 로고    scopus 로고
    • Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy
    • Kau, A.L. et al. Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy. Sci. Transl. Med. 7, 276ra24-276ra24 (2015).
    • (2015) Sci. Transl. Med. , vol.7 , pp. 276ra24-276ra24
    • Kau, A.L.1
  • 167
    • 79952748287 scopus 로고    scopus 로고
    • Unravelling the effects of the environment and host genotype on the gut microbiome
    • Spor, A., Koren, O. & Ley, R. Unravelling the effects of the environment and host genotype on the gut microbiome. Nat. Rev. Microbiol. 9, 279-290 (2011).
    • (2011) Nat. Rev. Microbiol. , vol.9 , pp. 279-290
    • Spor, A.1    Koren, O.2    Ley, R.3
  • 168
    • 84923813876 scopus 로고    scopus 로고
    • Dynamics ofBcells in germinal centres
    • De Silva, N.S.& Klein,U.Dynamics ofBcells in germinal centres. Nat. Rev. Immunol. 15, 137-148 (2015).
    • (2015) Nat. Rev. Immunol. , vol.15 , pp. 137-148
    • De Silva, N.S.1    Klein, U.2
  • 169
    • 84990888264 scopus 로고    scopus 로고
    • Germinal center B cell dynamics
    • Mesin, L., Ersching, J. & Victora, G.D. Germinal center B cell dynamics. Immunity 45, 471-482 (2016).
    • (2016) Immunity , vol.45 , pp. 471-482
    • Mesin, L.1    Ersching, J.2    Victora, G.D.3
  • 170
    • 33947212334 scopus 로고    scopus 로고
    • Recirculation of germinal center B cells: A multilevel selection strategy for antibody maturation
    • Or-Guil, M.,Wittenbrink, N.,Weiser, A.A. & Schuchhardt, J. Recirculation of germinal center B cells: a multilevel selection strategy for antibody maturation. Immunol. Rev. 216, 130-141 (2007).
    • (2007) Immunol. Rev. , vol.216 , pp. 130-141
    • Or-Guil, M.1    Wittenbrink, N.2    Weiser, A.A.3    Schuchhardt, J.4
  • 171
    • 80054919389 scopus 로고    scopus 로고
    • Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut
    • Mantis, N.J., Rol, N. & Corthesy, B. Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut. Mucosal Immunol. 4, 603-611 (2011).
    • (2011) Mucosal Immunol. , vol.4 , pp. 603-611
    • Mantis, N.J.1    Rol, N.2    Corthesy, B.3
  • 172
  • 173
    • 77954079810 scopus 로고    scopus 로고
    • IgA changes the rules of memory
    • Cerutti, A. Immunology. IgA changes the rules of memory. Science 328, 1646-1647 (2010).
    • (2010) Science , vol.328 , pp. 1646-1647
    • Immunology, C.A.1
  • 174
    • 0028950293 scopus 로고
    • Analyses ofhomologous rotavirus infection in themouse model
    • Burns, J.W. et al. Analyses ofhomologous rotavirus infection in themouse model. Virology 207, 143-153 (1995).
    • (1995) Virology , vol.207 , pp. 143-153
    • Burns, J.W.1
  • 175
    • 0029119340 scopus 로고
    • Long-term production of rotavirus antibody and protection against reinfection following a single infection of neonatal mice with murine rotavirus
    • McNeal, M.M. & Ward, R.L. Long-term production of rotavirus antibody and protection against reinfection following a single infection of neonatal mice with murine rotavirus. Virology 211, 474-480 (1995).
    • (1995) Virology , vol.211 , pp. 474-480
    • McNeal, M.M.1    Ward, R.L.2
  • 176
    • 0032532033 scopus 로고    scopus 로고
    • The memory B cell subset responsible for the secretory IgA response and protective humoral immunity to rotavirus expresses the intestinal homing receptor, alpha4beta7
    • Williams, M.B. et al. The memory B cell subset responsible for the secretory IgA response and protective humoral immunity to rotavirus expresses the intestinal homing receptor, alpha4beta7. J. Immunol. 161, 4227-4235 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 4227-4235
    • Williams, M.B.1
  • 177
    • 0023625368 scopus 로고
    • Circulating cholera antitoxin memory cells in the blood one year after oral cholera vaccination in humans
    • Lycke, N., Hellströ m, U. & Holmgren, J. Circulating cholera antitoxin memory cells in the blood one year after oral cholera vaccination in humans. Scand. J. Immunol. 26, 207-211 (1987).
    • (1987) Scand. J. Immunol. , vol.26 , pp. 207-211
    • Lycke, N.1    Hellströ, M.U.2    Holmgren, J.3
  • 178
    • 0023635901 scopus 로고
    • Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours of an oral challenge immunization
    • Lycke, N. & Holmgren, J. Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours of an oral challenge immunization. Scand. J. Immunol. 25, 407-412 (1987).
    • (1987) Scand. J. Immunol. , vol.25 , pp. 407-412
    • Lycke, N.1    Holmgren, J.2
  • 179
    • 0024513124 scopus 로고
    • Adoptive transfer of gut mucosal antitoxin memory by isolated B cells 1 year after oral immunization with cholera toxin
    • Lycke, N. & Holmgren, J. Adoptive transfer of gut mucosal antitoxin memory by isolated B cells 1 year after oral immunization with cholera toxin. Infect. Immun. 57, 1137-1141 (1989).
    • (1989) Infect. Immun. , vol.57 , pp. 1137-1141
    • Lycke, N.1    Holmgren, J.2
  • 180
    • 0027440322 scopus 로고
    • Stimulation of antigen-specific T-andB-cell memory in local as well as systemic lymphoid tissues following oral immunization with cholera toxin adjuvant
    • Vajdy, M. & Lycke,N. Stimulation of antigen-specific T-andB-cell memory in local as well as systemic lymphoid tissues following oral immunization with cholera toxin adjuvant. Immunology 80, 197-203 (1993).
    • (1993) Immunology , vol.80 , pp. 197-203
    • Vajdy, M.1    Lycke, N.2
  • 181
    • 0028886993 scopus 로고
    • Mucosal memory B cells retain the ability to produce IgM antibodies 2 years after oral immunization
    • Vajdy, M. & Lycke, N. Mucosal memory B cells retain the ability to produce IgM antibodies 2 years after oral immunization. Immunology 86, 336-342 (1995).
    • (1995) Immunology , vol.86 , pp. 336-342
    • Vajdy, M.1    Lycke, N.2
  • 182
    • 77958195796 scopus 로고    scopus 로고
    • Mucosal adjuvants and long-term memory development with special focus on CTA1-DD and other ADP-ribosylating toxins
    • Lycke, N. & Bemark, M. Mucosal adjuvants and long-term memory development with special focus on CTA1-DD and other ADP-ribosylating toxins. Mucosal Immunol. 3, 556-566 (2010).
    • (2010) Mucosal Immunol. , vol.3 , pp. 556-566
    • Lycke, N.1    Bemark, M.2
  • 183
    • 84958831765 scopus 로고    scopus 로고
    • A temporal switch in the germinal center determines differential output of memory B and plasma cells
    • Weisel, F.J., Zuccarino-Catania, G.V., Chikina, M. & Shlomchik, M.J. A temporal switch in the germinal center determines differential output of memory B and plasma cells. Immunity 44, 116-130 (2016).
    • (2016) Immunity , vol.44 , pp. 116-130
    • Weisel, F.J.1    Zuccarino-Catania, G.V.2    Chikina, M.3    Shlomchik, M.J.4
  • 185
    • 34548383012 scopus 로고    scopus 로고
    • New markers for murine memory B cells that define mutated and unmutated subsets
    • Anderson, S.M., Tomayko, M.M., Ahuja, A., Haberman, A.M. & Shlomchik, M.J. New markers for murine memory B cells that define mutated and unmutated subsets. J. Exp. Med. 204, 2103-2114 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 2103-2114
    • Anderson, S.M.1    Tomayko, M.M.2    Ahuja, A.3    Haberman, A.M.4    Shlomchik, M.J.5
  • 186
    • 79251591958 scopus 로고    scopus 로고
    • A unique role of the cholera toxin A1-DD adjuvant for long-term plasma and memory B cell development
    • Bemark, M. et al. A unique role of the cholera toxin A1-DD adjuvant for long-term plasma and memory B cell development. J. Immunol. 186, 1399-1410 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 1399-1410
    • Bemark, M.1
  • 187
    • 84861235461 scopus 로고    scopus 로고
    • Divergent transcriptional programming of class-specific B cell memory by T-bet and RORa
    • Wang, N.S. et al. Divergent transcriptional programming of class-specific B cell memory by T-bet and RORa. Nat. Immunol. 13, 604-611 (2012).
    • (2012) Nat. Immunol. , vol.13 , pp. 604-611
    • Wang, N.S.1
  • 188
    • 79955494239 scopus 로고    scopus 로고
    • Themajority of intestinal IgA and IgG plasmablasts in the human gut are antigen-specific
    • Benckert, J. et al. Themajority of intestinal IgA and IgG plasmablasts in the human gut are antigen-specific. J. Clin. Invest. 121, 1946-1955 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 1946-1955
    • Benckert, J.1
  • 189
    • 79952287439 scopus 로고    scopus 로고
    • IgA-producing plasma cells originate from germinal centers that are induced by B-cell receptor engagement in humans
    • Barone, F. et al. IgA-producing plasma cells originate from germinal centers that are induced by B-cell receptor engagement in humans. Gastroenterology 140, 947-956 (2011).
    • (2011) Gastroenterology , vol.140 , pp. 947-956
    • Barone, F.1
  • 190
    • 37349013401 scopus 로고    scopus 로고
    • Follicular shuttling of marginal zone B cells facilitates antigen transport
    • Cinamon, G., Zachariah, M.A., Lam, O.M., Foss, F.W. & Cyster, J.G. Follicular shuttling of marginal zone B cells facilitates antigen transport. Nat. Immunol. 9, 54-62 (2008).
    • (2008) Nat. Immunol. , vol.9 , pp. 54-62
    • Cinamon, G.1    Zachariah, M.A.2    Lam, O.M.3    Foss, F.W.4    Cyster, J.G.5
  • 191
    • 58149097584 scopus 로고    scopus 로고
    • The who, how and where of antigen presentation to B cells
    • Batista, F.D. & Harwood, N.E. The who, how and where of antigen presentation to B cells. Nat. Rev. Immunol. 9, 15-27 (2009).
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 15-27
    • Batista, F.D.1    Harwood, N.E.2
  • 192
    • 0037408501 scopus 로고    scopus 로고
    • B1 cells contribute to serum IgM, but not to intestinal IgA, production in gnotobiotic Ig allotype chimeric mice
    • Thurnheer, M.C., Zuercher, A.W., Cebra, J.J. & Bos, N.A. B1 cells contribute to serum IgM, but not to intestinal IgA, production in gnotobiotic Ig allotype chimeric mice. J. Immunol. 170, 4564-4571 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 4564-4571
    • Thurnheer, M.C.1    Zuercher, A.W.2    Cebra, J.J.3    Bos, N.A.4
  • 193
    • 0023675994 scopus 로고
    • Cross-protection by B subunit-whole cell cholera vaccine against diarrhea associated with heat-labile toxin-producing enterotoxigenic Escherichia coli: Results of a large-scale field trial
    • Clemens, J.D. et al. Cross-protection by B subunit-whole cell cholera vaccine against diarrhea associated with heat-labile toxin-producing enterotoxigenic Escherichia coli: results of a large-scale field trial. J. Infect. Dis. 158, 372-377 (1988).
    • (1988) J. Infect. Dis. , vol.158 , pp. 372-377
    • Clemens, J.D.1
  • 194
    • 84928920286 scopus 로고    scopus 로고
    • Filter-dense multicolor microscopy
    • Kijani, S. et al. Filter-dense multicolor microscopy. PLoS ONE 10, e0119499 (2015).
    • (2015) PLoS ONE , vol.10 , pp. e0119499
    • Kijani, S.1


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