메뉴 건너뛰기




Volumn 112, Issue 4, 2004, Pages 509-520

Divide and conquer: The importance of cell division in regulating B-cell responses

Author keywords

Antibody responses; B cells; Cell division; Ig secretion; Lymphocyte differentiation

Indexed keywords

ALPHA INTERFERON; ANTIBODY; ANTIGEN; B LYMPHOCYTE RECEPTOR; CD70 ANTIGEN; CYTOKINE; DIPHTHERIA VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; LYMPHOTOXIN; TETANUS TOXOID; TUMOR NECROSIS FACTOR;

EID: 4043108358     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2004.01950.x     Document Type: Review
Times cited : (102)

References (110)
  • 1
    • 0023818702 scopus 로고
    • The role of helper T cell products in mouse B cell differentiation and isotype regulation
    • Coffman RL, Seymour BW, Lebman DA et al. The role of helper T cell products in mouse B cell differentiation and isotype regulation. Immunol Rev 1988; 102:5-28.
    • (1988) Immunol Rev , vol.102 , pp. 5-28
    • Coffman, R.L.1    Seymour, B.W.2    Lebman, D.A.3
  • 2
    • 0025210071 scopus 로고
    • Immunoglobulin class switching: Molecular and cellular analysis
    • Esser C, Radbruch A. Immunoglobulin class switching: molecular and cellular analysis. Ann Rev Immunol 1990; 8:717-35.
    • (1990) Ann Rev Immunol , vol.8 , pp. 717-735
    • Esser, C.1    Radbruch, A.2
  • 3
    • 0023785192 scopus 로고
    • Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures
    • Lebman DA, Coffman RL. Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures. J Exp Med 1988; 168:853-62.
    • (1988) J Exp Med , vol.168 , pp. 853-862
    • Lebman, D.A.1    Coffman, R.L.2
  • 4
    • 0025329369 scopus 로고
    • Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type beta-induced isotype switching
    • Lebman DA, Nomura DY, Coffman RL, Lee FD. Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type beta-induced isotype switching. Proc Natl Acad Sci USA 1990; 87:3962-6.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3962-3966
    • Lebman, D.A.1    Nomura, D.Y.2    Coffman, R.L.3    Lee, F.D.4
  • 5
    • 0025214025 scopus 로고
    • Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: Interleukin-4 plus lipopolysaccharide-directed switching to C epsilon
    • Rothman P, Chen YY, Lutzker S, Li SC, Stewart V, Coffman R, Alt FW. Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C epsilon. Mol Cell Biol 1990; 10:1672-9.
    • (1990) Mol Cell Biol , vol.10 , pp. 1672-1679
    • Rothman, P.1    Chen, Y.Y.2    Lutzker, S.3    Li, S.C.4    Stewart, V.5    Coffman, R.6    Alt, F.W.7
  • 6
    • 0024446350 scopus 로고
    • Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes
    • Coffman RL, Lebman DA, Shrader B. Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes. J Exp Med 1989; 170:1039-44.
    • (1989) J Exp Med , vol.170 , pp. 1039-1044
    • Coffman, R.L.1    Lebman, D.A.2    Shrader, B.3
  • 7
    • 0023197097 scopus 로고
    • Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
    • Snapper CM, Paul WE. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 1987; 236:944-7.
    • (1987) Science , vol.236 , pp. 944-947
    • Snapper, C.M.1    Paul, W.E.2
  • 8
    • 0027523093 scopus 로고
    • Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells
    • McIntyre TM, Klinman DR, Rothman P, Lugo M, Dasch JR, Mond JJ, Snapper CM. Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells. J Exp Med 1993; 177:1031-7.
    • (1993) J Exp Med , vol.177 , pp. 1031-1037
    • McIntyre, T.M.1    Klinman, D.R.2    Rothman, P.3    Lugo, M.4    Dasch, J.R.5    Mond, J.J.6    Snapper, C.M.7
  • 9
    • 0026445919 scopus 로고
    • Human B lymphocytes: Phenotype, proliferation, and differentiation
    • Banchereau J, Rousset F. Human B lymphocytes: phenotype, proliferation, and differentiation. Adv Immunol 1992; 52:125-262.
    • (1992) Adv Immunol , vol.52 , pp. 125-262
    • Banchereau, J.1    Rousset, F.2
  • 11
    • 0028082477 scopus 로고
    • Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3
    • Briere F, Servet-Delprat C, Bridon JM, Saint-Remy JM, Banchereau J. Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3. J Exp Med 1994; 179:757-62.
    • (1994) J Exp Med , vol.179 , pp. 757-762
    • Briere, F.1    Servet-Delprat, C.2    Bridon, J.M.3    Saint-Remy, J.M.4    Banchereau, J.5
  • 12
    • 0030958893 scopus 로고    scopus 로고
    • Human dendritic cells skew isotype switching of CD40-activated naive B cells towards IgA1 and IgA2
    • Fayette J, Dubois B, Vandenabeele S et al. Human dendritic cells skew isotype switching of CD40-activated naive B cells towards IgA1 and IgA2. J Exp Med 1997; 185:1909-18.
    • (1997) J Exp Med , vol.185 , pp. 1909-1918
    • Fayette, J.1    Dubois, B.2    Vandenabeele, S.3
  • 13
    • 0026563156 scopus 로고
    • Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A
    • Defrance T, Vanbervliet B, Briere F, Durand I, Rousset F, Banchereau J. Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J Exp Med 1992; 175:671-82.
    • (1992) J Exp Med , vol.175 , pp. 671-682
    • Defrance, T.1    Vanbervliet, B.2    Briere, F.3    Durand, I.4    Rousset, F.5    Banchereau, J.6
  • 14
    • 0026568296 scopus 로고
    • Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumor necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production
    • Gauchat JF, Aversa G, Gascan H, de Vries JE. Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumor necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production. Int Immunol 1992; 4:397-406.
    • (1992) Int Immunol , vol.4 , pp. 397-406
    • Gauchat, J.F.1    Aversa, G.2    Gascan, H.3    De Vries, J.E.4
  • 15
    • 0029087972 scopus 로고
    • IL-4 plus CD40 monoclonal antibody induces human B cells gamma subclass-specific isotype switch: Switching to gamma 1, gamma 3, and gamma 4, but not gamma 2
    • Fujieda S, Zhang K, Saxon A. IL-4 plus CD40 monoclonal antibody induces human B cells gamma subclass-specific isotype switch: switching to gamma 1, gamma 3, and gamma 4, but not gamma 2. J Immunol 1995; 155:2318-28.
    • (1995) J Immunol , vol.155 , pp. 2318-2328
    • Fujieda, S.1    Zhang, K.2    Saxon, A.3
  • 16
    • 0030426374 scopus 로고    scopus 로고
    • Direct evidence that gamma 1 and gamma 3 switching in human B cells is interleukin-10 dependent
    • Fujieda S, Saxon A, Zhang K. Direct evidence that gamma 1 and gamma 3 switching in human B cells is interleukin-10 dependent. Mol Immunol 1996; 33:1335-43.
    • (1996) Mol Immunol , vol.33 , pp. 1335-1343
    • Fujieda, S.1    Saxon, A.2    Zhang, K.3
  • 17
    • 11144355735 scopus 로고    scopus 로고
    • Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells
    • Pene J, Gauchat JF, Lecart S et al. Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells. J Immunol 2004; 172:5154-7.
    • (2004) J Immunol , vol.172 , pp. 5154-5157
    • Pene, J.1    Gauchat, J.F.2    Lecart, S.3
  • 18
    • 0026093417 scopus 로고
    • Isotype switching in anti-immunoglobulin-activated B lymphoblasts: Differential requirements for interleukin 4 and other lymphokines to elicit membrane vs. secreted IgG1
    • Purkerson JM, Isakson PC. Isotype switching in anti-immunoglobulin- activated B lymphoblasts: differential requirements for interleukin 4 and other lymphokines to elicit membrane vs. secreted IgG1. Eur J Immunol 1991; 21:707-14.
    • (1991) Eur J Immunol , vol.21 , pp. 707-714
    • Purkerson, J.M.1    Isakson, P.C.2
  • 19
    • 0028895929 scopus 로고
    • Multivalent, but not divalent, antigen receptor cross-linkers synergize with CD40 ligand for induction of Ig synthesis and class switching in normal murine B cells. A redefinition of the TI-2 vs T cell-dependent antigen dichotomy
    • Snapper CM, Kehry MR, Castle BE, Mond JJ. Multivalent, but not divalent, antigen receptor cross-linkers synergize with CD40 ligand for induction of Ig synthesis and class switching in normal murine B cells. A redefinition of the TI-2 vs T cell-dependent antigen dichotomy. J Immunol 1995; 154:1177-87.
    • (1995) J Immunol , vol.154 , pp. 1177-1187
    • Snapper, C.M.1    Kehry, M.R.2    Castle, B.E.3    Mond, J.J.4
  • 20
    • 9344268861 scopus 로고    scopus 로고
    • IL-10 selectively regulates murine Ig isotype switching
    • Shparago N, Zelazowski P, Jin L et al. IL-10 selectively regulates murine Ig isotype switching. Int Immunol 1996; 8:781-90.
    • (1996) Int Immunol , vol.8 , pp. 781-790
    • Shparago, N.1    Zelazowski, P.2    Jin, L.3
  • 21
    • 0028916191 scopus 로고
    • Novel in vitro model for high-rate IgA class switching
    • McIntyre TM, Kehry MR, Snapper CM. Novel in vitro model for high-rate IgA class switching. J Immunol 1995; 154:3156-61.
    • (1995) J Immunol , vol.154 , pp. 3156-3161
    • McIntyre, T.M.1    Kehry, M.R.2    Snapper, C.M.3
  • 22
    • 0032032241 scopus 로고    scopus 로고
    • CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+ IgD+ B cell line
    • Cerutti A, Zan H, Schaffer A, Bergsagel L, Harindranath N, Max EE, Casali P. CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+ IgD+ B cell line. J Immunol 1998; 160:2145-57.
    • (1998) J Immunol , vol.160 , pp. 2145-2157
    • Cerutti, A.1    Zan, H.2    Schaffer, A.3    Bergsagel, L.4    Harindranath, N.5    Max, E.E.6    Casali, P.7
  • 23
    • 0032534070 scopus 로고    scopus 로고
    • CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: Evidence for TGF-beta but not IL-10-dependent direct S mu → S alpha and sequential S mu → S gamma, S gamma → S alpha DNA recombination
    • Zan H, Cerutti A, Dramitinos P, Schaffer A, Casali P. CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: evidence for TGF-beta but not IL-10-dependent direct S mu → S alpha and sequential S mu → S gamma, S gamma → S alpha DNA recombination. J Immunol 1998; 161:5217-25.
    • (1998) J Immunol , vol.161 , pp. 5217-5225
    • Zan, H.1    Cerutti, A.2    Dramitinos, P.3    Schaffer, A.4    Casali, P.5
  • 25
    • 0028262128 scopus 로고
    • Determination of lymphocyte division by flow cytometry
    • Lyons AB, Parish CR. Determination of lymphocyte division by flow cytometry. J Immunol Meth 1994; 171:131-7.
    • (1994) J Immunol Meth , vol.171 , pp. 131-137
    • Lyons, A.B.1    Parish, C.R.2
  • 26
    • 0030037519 scopus 로고    scopus 로고
    • B cell differentiation and isotype switching is related to division cycle number
    • Hodgkin PD, Lee JH, Lyons AB. B cell differentiation and isotype switching is related to division cycle number. J Exp Med 1996; 184:277-81.
    • (1996) J Exp Med , vol.184 , pp. 277-281
    • Hodgkin, P.D.1    Lee, J.H.2    Lyons, A.B.3
  • 27
    • 0031905273 scopus 로고    scopus 로고
    • Cell division number regulates IgG1 and IgE switching of B cells following stimulation by CD40 ligand and IL-4
    • Hasbold J, Lyons AB, Kehry MR, Hodgkin PD. Cell division number regulates IgG1 and IgE switching of B cells following stimulation by CD40 ligand and IL-4. Eur J Immunol 1998; 28:1040-51.
    • (1998) Eur J Immunol , vol.28 , pp. 1040-1051
    • Hasbold, J.1    Lyons, A.B.2    Kehry, M.R.3    Hodgkin, P.D.4
  • 28
    • 0032757402 scopus 로고    scopus 로고
    • Switching to IgG3, IgG2b, and IgA is division linked and independent, revealing a stochastic framework for describing differentiation
    • Deenick EK, Hasbold J, Hodgkin PD. Switching to IgG3, IgG2b, and IgA is division linked and independent, revealing a stochastic framework for describing differentiation. J Immunol 1999; 163:4707-14.
    • (1999) J Immunol , vol.163 , pp. 4707-4714
    • Deenick, E.K.1    Hasbold, J.2    Hodgkin, P.D.3
  • 29
    • 0037108509 scopus 로고    scopus 로고
    • Isotype switching by human B cells is division-associated and regulated by cytokines
    • Tangye SG, Ferguson A, Avery DT, Ma CS, Hodgkin PD. Isotype switching by human B cells is division-associated and regulated by cytokines. J Immunol 2002; 169:4298-306.
    • (2002) J Immunol , vol.169 , pp. 4298-4306
    • Tangye, S.G.1    Ferguson, A.2    Avery, D.T.3    Ma, C.S.4    Hodgkin, P.D.5
  • 30
    • 0026497315 scopus 로고
    • Functional and molecular characterization of single, (4-hydroxy-3- nitrophenyl) acetyl (NP)-specific, IgG1 + B cells from antibody-secreting and memory B cell pathways in the C57BL/6 immune response to NP
    • Lalor PA, Nossal GJ, Sanderson RD, McHeyzer-Williams MG. Functional and molecular characterization of single, (4-hydroxy-3-nitrophenyl) acetyl (NP)-specific, IgG1 + B cells from antibody-secreting and memory B cell pathways in the C57BL/6 immune response to NP. Eur J Immunol 1992; 22:3001-11.
    • (1992) Eur J Immunol , vol.22 , pp. 3001-3011
    • Lalor, P.A.1    Nossal, G.J.2    Sanderson, R.D.3    McHeyzer-Williams, M.G.4
  • 31
    • 0347756722 scopus 로고    scopus 로고
    • Evidence from the generation of immunoglobulin G secreting cells that stochastic mechanisms regulate lymphocyte differentiation
    • Hasbold J, Corcoran LM, Tarlinton DM, Tangye SG, Hodgkin PD. Evidence from the generation of immunoglobulin G secreting cells that stochastic mechanisms regulate lymphocyte differentiation. Nat Immunol 2004; 5:55-63.
    • (2004) Nat Immunol , vol.5 , pp. 55-63
    • Hasbold, J.1    Corcoran, L.M.2    Tarlinton, D.M.3    Tangye, S.G.4    Hodgkin, P.D.5
  • 32
    • 0032828961 scopus 로고    scopus 로고
    • Integrating signals from IFN-gamma and IL-4 by B cells: Positive and negative effects on CD40 ligand-induced proliferation, survival, and division-linked isotype switching to IgG1, IgE, and IgG2a
    • Hasbold J, Hong JS, Kehry MR, Hodgkin PD. Integrating signals from IFN-gamma and IL-4 by B cells: positive and negative effects on CD40 ligand-induced proliferation, survival, and division-linked isotype switching to IgG1, IgE, and IgG2a. J Immunol 1999; 163:4175-81.
    • (1999) J Immunol , vol.163 , pp. 4175-4181
    • Hasbold, J.1    Hong, J.S.2    Kehry, M.R.3    Hodgkin, P.D.4
  • 33
    • 0025872881 scopus 로고
    • Interleukin-4 enhances anti-IgM stimulation of B cells by improving cell viability and by increasing the sensitivity of B cells to the anti-IgM signal
    • Hodgkin PD, Go NF, Cupp JE, Howard M. Interleukin-4 enhances anti-IgM stimulation of B cells by improving cell viability and by increasing the sensitivity of B cells to the anti-IgM signal. Cell Immunol 1991; 134:14-30.
    • (1991) Cell Immunol , vol.134 , pp. 14-30
    • Hodgkin, P.D.1    Go, N.F.2    Cupp, J.E.3    Howard, M.4
  • 35
    • 0023933655 scopus 로고
    • Differential regulation of IgG1 and IgE synthesis by interleukin 4
    • Snapper CM, Finkelman FD, Paul WE. Differential regulation of IgG1 and IgE synthesis by interleukin 4. J Exp Med 1988; 167:183-96.
    • (1988) J Exp Med , vol.167 , pp. 183-196
    • Snapper, C.M.1    Finkelman, F.D.2    Paul, W.E.3
  • 36
    • 0023202716 scopus 로고
    • B cell growth-promoting activity of recombinant human interleukin 4
    • Defrance T, Vanbervliet B, Aubry JP et al. B cell growth-promoting activity of recombinant human interleukin 4. J Immunol 1987; 139:1135-41.
    • (1987) J Immunol , vol.139 , pp. 1135-1141
    • Defrance, T.1    Vanbervliet, B.2    Aubry, J.P.3
  • 37
    • 0028980745 scopus 로고
    • TGF-beta 1 and cyclic AMP promote apoptosis in resting human B lymphocytes
    • Lomo J, Blomhoff HK, Beiske K, Stokke T, Smeland EB. TGF-beta 1 and cyclic AMP promote apoptosis in resting human B lymphocytes. J Immunol 1995; 154:1634-43.
    • (1995) J Immunol , vol.154 , pp. 1634-1643
    • Lomo, J.1    Blomhoff, H.K.2    Beiske, K.3    Stokke, T.4    Smeland, E.B.5
  • 38
    • 0035054598 scopus 로고    scopus 로고
    • B cells activated via CD40 and IL-4 undergo a division burst but require continued stimulation to maintain division, survival and differentiation
    • Rush JS, Hodgkin PD. B cells activated via CD40 and IL-4 undergo a division burst but require continued stimulation to maintain division, survival and differentiation. Eur J Immunol 2001; 31:1150-9.
    • (2001) Eur J Immunol , vol.31 , pp. 1150-1159
    • Rush, J.S.1    Hodgkin, P.D.2
  • 39
    • 0037220807 scopus 로고    scopus 로고
    • A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells
    • Tangye SG, Avery DT, Hodgkin PD. A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells. J Immunol 2003; 170:261-9.
    • (2003) J Immunol , vol.170 , pp. 261-269
    • Tangye, S.G.1    Avery, D.T.2    Hodgkin, P.D.3
  • 40
    • 85047690330 scopus 로고    scopus 로고
    • BAFF selectively enhances the survival of plasmablasts generated from human memory B cells
    • Avery DT, Kalled SL, Ellyard JE et al. BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J Clin Invest 2003; 112:286-97.
    • (2003) J Clin Invest , vol.112 , pp. 286-297
    • Avery, D.T.1    Kalled, S.L.2    Ellyard, J.E.3
  • 41
    • 0030001674 scopus 로고    scopus 로고
    • Immunological memory and protective immunity: Understanding their relation
    • Ahmed R, Gray D. Immunological memory and protective immunity: understanding their relation. Science 1996; 272:54-60.
    • (1996) Science , vol.272 , pp. 54-60
    • Ahmed, R.1    Gray, D.2
  • 42
    • 0035080069 scopus 로고    scopus 로고
    • Delayed and deficient establishment of the long-term bone marrow plasma cell pool during early life
    • Pihlgren M, Schallert N, Tougne C et al. Delayed and deficient establishment of the long-term bone marrow plasma cell pool during early life. Eur J Immunol 2001; 31:939-46.
    • (2001) Eur J Immunol , vol.31 , pp. 939-946
    • Pihlgren, M.1    Schallert, N.2    Tougne, C.3
  • 43
    • 0017735423 scopus 로고
    • The class of surface immunoglobulin on virgin and memory B lymphocytes
    • Coffman RL, Cohn M. The class of surface immunoglobulin on virgin and memory B lymphocytes. J Immunol 1977; 118:1806-15.
    • (1977) J Immunol , vol.118 , pp. 1806-1815
    • Coffman, R.L.1    Cohn, M.2
  • 44
    • 0023103574 scopus 로고
    • Isolation of high-affinity memory B cells: Phycoerythrin as a probe for antigen-binding cells
    • Hayakawa K, Ishii R, Yamasaki K, Kishimoto T, Hardy RR. Isolation of high-affinity memory B cells: phycoerythrin as a probe for antigen-binding cells. Proc Natl Acad Sci USA 1987; 84:1379-83.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1379-1383
    • Hayakawa, K.1    Ishii, R.2    Yamasaki, K.3    Kishimoto, T.4    Hardy, R.R.5
  • 45
    • 0028964162 scopus 로고
    • Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2
    • Liu YJ, Barthelemy C, de Bouteiller O, Arpin C, Durand I, Banchereau J. Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2. Immunity 1995; 2:239-48.
    • (1995) Immunity , vol.2 , pp. 239-248
    • Liu, Y.J.1    Barthelemy, C.2    De Bouteiller, O.3    Arpin, C.4    Durand, I.5    Banchereau, J.6
  • 46
    • 0032932959 scopus 로고    scopus 로고
    • Correlation analysis between frequencies of circulating antigen-specific IgG-bearing memory B cells and serum titers of antigen-specific IgG
    • Leyendeckers H, Odendahl M, Lohndorf A et al. Correlation analysis between frequencies of circulating antigen-specific IgG-bearing memory B cells and serum titers of antigen-specific IgG. Eur J Immunol 1999; 29:1406-17.
    • (1999) Eur J Immunol , vol.29 , pp. 1406-1417
    • Leyendeckers, H.1    Odendahl, M.2    Lohndorf, A.3
  • 48
    • 2342575532 scopus 로고    scopus 로고
    • Ag-selected Ig-secreting cells persist in human spleen as well as bone marrow
    • Ellyard JE, Avery DT, Phan TG, Hodgkin PD, Tangye SG. Ag-selected Ig-secreting cells persist in human spleen as well as bone marrow. Blood 2004; 103:3805-12.
    • (2004) Blood , vol.103 , pp. 3805-3812
    • Ellyard, J.E.1    Avery, D.T.2    Phan, T.G.3    Hodgkin, P.D.4    Tangye, S.G.5
  • 49
    • 0036171910 scopus 로고    scopus 로고
    • Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory
    • Martin SW, Goodnow CC. Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory [see comments]. Nat Immunol 2002; 3:182-8.
    • (2002) Nat Immunol , vol.3 , pp. 182-188
    • Martin, S.W.1    Goodnow, C.C.2
  • 50
    • 0037147182 scopus 로고    scopus 로고
    • A distinct signaling pathway used by the IgG-containing B cell antigen receptor
    • Wakabayashi C, Adachi T, Wienands J, Tsubata T. A distinct signaling pathway used by the IgG-containing B cell antigen receptor. Science 2002; 298:2392-5.
    • (2002) Science , vol.298 , pp. 2392-2395
    • Wakabayashi, C.1    Adachi, T.2    Wienands, J.3    Tsubata, T.4
  • 51
    • 0025951891 scopus 로고
    • Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
    • erratum appears in Eur J Immunol 1992; 22:615
    • Liu YJ, Zhang J, Lane PJ, Chan EY, MacLennan IC. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur J Immunol 1991; 21:2951-62 [erratum appears in Eur J Immunol 1992; 22:615].
    • (1991) Eur J Immunol , vol.21 , pp. 2951-2962
    • Liu, Y.J.1    Zhang, J.2    Lane, P.J.3    Chan, E.Y.4    MacLennan, I.C.5
  • 53
    • 0034599971 scopus 로고    scopus 로고
    • Antigen-specific B cell memory: Expression and replenishment of a novel B220 (-) memory B cell compartment
    • McHeyzer-Williams LJ, Cool M, McHeyzer-Williams MG. Antigen-specific B cell memory: expression and replenishment of a novel B220 (-) memory B cell compartment. J Exp Med 2000; 191:1149-66.
    • (2000) J Exp Med , vol.191 , pp. 1149-1166
    • McHeyzer-Williams, L.J.1    Cool, M.2    McHeyzer-Williams, M.G.3
  • 54
    • 0022610270 scopus 로고
    • In vitro activation of murine antigen-specific memory B cells by a T-dependent antigen
    • Yefenof E, Sanders VM, Uhr JW, Vitetta ES. In vitro activation of murine antigen-specific memory B cells by a T-dependent antigen. J Immunol 1986; 137:85-90.
    • (1986) J Immunol , vol.137 , pp. 85-90
    • Yefenof, E.1    Sanders, V.M.2    Uhr, J.W.3    Vitetta, E.S.4
  • 55
    • 0022630009 scopus 로고
    • Human peripheral blood B lymphocyte subpopulations: Functional and phenotypic analysis of surface IgD positive and negative subsets
    • Jelinek DF, Splawski JB, Lipsky PE. Human peripheral blood B lymphocyte subpopulations: functional and phenotypic analysis of surface IgD positive and negative subsets. J Immunol 1986; 136:83-92.
    • (1986) J Immunol , vol.136 , pp. 83-92
    • Jelinek, D.F.1    Splawski, J.B.2    Lipsky, P.E.3
  • 56
    • 0030984447 scopus 로고    scopus 로고
    • Memory B cells are biased towards terminal differentiation: A strategy that may prevent repertoire freezing
    • Arpin C, Banchereau J, Liu YJ. Memory B cells are biased towards terminal differentiation: a strategy that may prevent repertoire freezing. J Exp Med 1997; 186:931-40.
    • (1997) J Exp Med , vol.186 , pp. 931-940
    • Arpin, C.1    Banchereau, J.2    Liu, Y.J.3
  • 57
    • 0031229725 scopus 로고    scopus 로고
    • Memory, but not naive, peripheral blood B lymphocytes differentiate into Ig-secreting cells after CD40 ligation and costimulation with IL-4 and the differentiation factors IL-2, IL-10, and IL-3
    • Kindler V, Zubler RH. Memory, but not naive, peripheral blood B lymphocytes differentiate into Ig-secreting cells after CD40 ligation and costimulation with IL-4 and the differentiation factors IL-2, IL-10, and IL-3. J Immunol 1997; 159:2085-90.
    • (1997) J Immunol , vol.159 , pp. 2085-2090
    • Kindler, V.1    Zubler, R.H.2
  • 58
    • 0027324003 scopus 로고
    • B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells
    • Nonoyama S, Hollenbaugh D, Aruffo A, Ledbetter JA, Ochs HD. B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells. J Exp Med 1993; 178:1097-102.
    • (1993) J Exp Med , vol.178 , pp. 1097-1102
    • Nonoyama, S.1    Hollenbaugh, D.2    Aruffo, A.3    Ledbetter, J.A.4    Ochs, H.D.5
  • 59
    • 0029987922 scopus 로고    scopus 로고
    • The differentiation of human memory B cells into specific antibody-secreting cells is CD40 independent
    • Silvy A, Lagresle C, Bella C, Defrance T. The differentiation of human memory B cells into specific antibody-secreting cells is CD40 independent. Eur J Immunol 1996; 26:517-24.
    • (1996) Eur J Immunol , vol.26 , pp. 517-524
    • Silvy, A.1    Lagresle, C.2    Bella, C.3    Defrance, T.4
  • 60
    • 0032476617 scopus 로고    scopus 로고
    • Identification of functional human splenic memory B cells by expression of CD148 and CD27
    • Tangye SG, Liu YJ, Aversa G, Phillips JH, de Vries JE. Identification of functional human splenic memory B cells by expression of CD148 and CD27. J Exp Med 1998; 188:1691-703.
    • (1998) J Exp Med , vol.188 , pp. 1691-1703
    • Tangye, S.G.1    Liu, Y.J.2    Aversa, G.3    Phillips, J.H.4    De Vries, J.E.5
  • 61
    • 0032476611 scopus 로고    scopus 로고
    • Human immunoglobulin (Ig) M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells
    • Klein U, Rajewsky K, Kuppers R. Human immunoglobulin (Ig) M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J Exp Med 1998; 188:1679-89.
    • (1998) J Exp Med , vol.188 , pp. 1679-1689
    • Klein, U.1    Rajewsky, K.2    Kuppers, R.3
  • 62
    • 0030786425 scopus 로고    scopus 로고
    • B cell subpopulations separated by CD27 and crucial collaboration of CD27+ B cells and helper T cells in immunoglobulin production
    • Agematsu K, Nagumo H, Yang FC et al. B cell subpopulations separated by CD27 and crucial collaboration of CD27+ B cells and helper T cells in immunoglobulin production. Eur J Immunol 1997; 27:2073-9.
    • (1997) Eur J Immunol , vol.27 , pp. 2073-2079
    • Agematsu, K.1    Nagumo, H.2    Yang, F.C.3
  • 63
    • 0036080366 scopus 로고    scopus 로고
    • CD84 is upregulated on a major population of human memory B cells and recruits the SH2-domain containing proteins SAP and EAT-2
    • Tangye SG, van de Weerdt BCM, Avery DT, Hodgkin PD. CD84 is upregulated on a major population of human memory B cells and recruits the SH2-domain containing proteins SAP and EAT-2. Eur J Immunol 2002; 32:1640-9.
    • (2002) Eur J Immunol , vol.32 , pp. 1640-1649
    • Tangye, S.G.1    Van De Weerdt, B.C.M.2    Avery, D.T.3    Hodgkin, P.D.4
  • 64
    • 0037438633 scopus 로고    scopus 로고
    • Intrinsic differences in the proliferation of naïve and memory human B cells as a mechanism for enhanced secondary immune responses
    • Tangye SG, Avery DT, Deenick EK, Hodgkin PD. Intrinsic differences in the proliferation of naïve and memory human B cells as a mechanism for enhanced secondary immune responses. J Immunol 2003; 170:686-94.
    • (2003) J Immunol , vol.170 , pp. 686-694
    • Tangye, S.G.1    Avery, D.T.2    Deenick, E.K.3    Hodgkin, P.D.4
  • 66
    • 0033568010 scopus 로고    scopus 로고
    • The human B cell response to IL-13 is dependent on cellular phenotype as well as mode of activation
    • Ford D, Sheehan C, Girasole C et al. The human B cell response to IL-13 is dependent on cellular phenotype as well as mode of activation. J Immunol 1999; 163:3185-93.
    • (1999) J Immunol , vol.163 , pp. 3185-3193
    • Ford, D.1    Sheehan, C.2    Girasole, C.3
  • 67
    • 0037073930 scopus 로고    scopus 로고
    • Maintenance of serological memory by polyclonal activation of human memory B cells
    • Bernasconi NL, Traggiai E, Lanzavecchia A. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 2002; 298:2199-202.
    • (2002) Science , vol.298 , pp. 2199-2202
    • Bernasconi, N.L.1    Traggiai, E.2    Lanzavecchia, A.3
  • 68
    • 0038142387 scopus 로고    scopus 로고
    • A role for Toll-like receptors in acquired immunity: Up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
    • Bernasconi NL, Onai N, Lanzavecchia A. A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells. Blood 2003; 101:4500-4.
    • (2003) Blood , vol.101 , pp. 4500-4504
    • Bernasconi, N.L.1    Onai, N.2    Lanzavecchia, A.3
  • 69
    • 0020624571 scopus 로고
    • The role of B cell proliferation in the generation of immunoglobulin-secreting cells in man
    • Jelinek DF, Lipsky PE. The role of B cell proliferation in the generation of immunoglobulin-secreting cells in man. J Immunol 1983; 130:2597-604.
    • (1983) J Immunol , vol.130 , pp. 2597-2604
    • Jelinek, D.F.1    Lipsky, P.E.2
  • 70
    • 2642554833 scopus 로고    scopus 로고
    • CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations
    • Arce S, Luger E, Muehlinghaus G et al. CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations. J Leuk Biol 2004; 75:1022-8.
    • (2004) J Leuk Biol , vol.75 , pp. 1022-1028
    • Arce, S.1    Luger, E.2    Muehlinghaus, G.3
  • 72
    • 0031913668 scopus 로고    scopus 로고
    • IL-10 interrupts memory B cell expansion in the germinal center by inducing differentiation into plasma cells
    • Choe J, Choi YS. IL-10 interrupts memory B cell expansion in the germinal center by inducing differentiation into plasma cells. Eur J Immunol 1998; 28:508-15.
    • (1998) Eur J Immunol , vol.28 , pp. 508-515
    • Choe, J.1    Choi, Y.S.2
  • 73
    • 0033849422 scopus 로고    scopus 로고
    • Regulation of CD27 expression in the course of germinal center B cell differentiation: The pivotal role of IL-10
    • Jung J, Choe J, Li L, Choi YS. Regulation of CD27 expression in the course of germinal center B cell differentiation: the pivotal role of IL-10. Eur J Immunol 2000; 30:2437-43.
    • (2000) Eur J Immunol , vol.30 , pp. 2437-2443
    • Jung, J.1    Choe, J.2    Li, L.3    Choi, Y.S.4
  • 74
    • 0037128644 scopus 로고    scopus 로고
    • Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population
    • O'Connor BP, Cascalho M, Noelle RJ. Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population. J Exp Med 2002; 195:737-45.
    • (2002) J Exp Med , vol.195 , pp. 737-745
    • O'Connor, B.P.1    Cascalho, M.2    Noelle, R.J.3
  • 75
    • 0033566294 scopus 로고    scopus 로고
    • Reactive plasmacytoses are expansions of plasmablasts retaining the capacity to differentiate into plasma cells
    • Jego G, Robillard N, Puthier D et al. Reactive plasmacytoses are expansions of plasmablasts retaining the capacity to differentiate into plasma cells. Blood 1999; 94:701-12.
    • (1999) Blood , vol.94 , pp. 701-712
    • Jego, G.1    Robillard, N.2    Puthier, D.3
  • 76
  • 77
    • 0036754302 scopus 로고    scopus 로고
    • Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses
    • Balázs M, Martin F, Zhou T, Kearney JF. Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 2002; 17:341-52.
    • (2002) Immunity , vol.17 , pp. 341-352
    • Balázs, M.1    Martin, F.2    Zhou, T.3    Kearney, J.F.4
  • 78
    • 0026599838 scopus 로고
    • Generation of nondividing high rate Ig-secreting plasma cells in cultures of human B cells stimulated with anti-CD3-activated T cells
    • Vernino L, McAnally LM, Ramberg J, Lipsky PE. Generation of nondividing high rate Ig-secreting plasma cells in cultures of human B cells stimulated with anti-CD3-activated T cells. J Immunol 1992; 148:404-10.
    • (1992) J Immunol , vol.148 , pp. 404-410
    • Vernino, L.1    McAnally, L.M.2    Ramberg, J.3    Lipsky, P.E.4
  • 79
    • 0032100715 scopus 로고    scopus 로고
    • Arrest of B lymphocyte terminal differentiation by CD40 signaling: Mechanism for lack of antibody-secreting cells in germinal centers
    • Randall TD, Heath AW, Santos-Argumedo L, Howard MC, Weissman IL, Lund FE. Arrest of B lymphocyte terminal differentiation by CD40 signaling: mechanism for lack of antibody-secreting cells in germinal centers. Immunity 1998; 8:733-42.
    • (1998) Immunity , vol.8 , pp. 733-742
    • Randall, T.D.1    Heath, A.W.2    Santos-Argumedo, L.3    Howard, M.C.4    Weissman, I.L.5    Lund, F.E.6
  • 80
    • 1842840003 scopus 로고    scopus 로고
    • Tracking human antigen-specific memory B cells: A sensitive and generalized ELISPOT system
    • Crotty S, Aubert RD, Glidewell J, Ahmed R. Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system. J Immunol Meth 2004; 286:111-22.
    • (2004) J Immunol Meth , vol.286 , pp. 111-122
    • Crotty, S.1    Aubert, R.D.2    Glidewell, J.3    Ahmed, R.4
  • 81
    • 0035854521 scopus 로고    scopus 로고
    • Arrested differentiation, the self-renewing memory lymphocyte, and vaccination
    • Fearon DT, Manders P, Wagner SD. Arrested differentiation, the self-renewing memory lymphocyte, and vaccination. Science 2001; 293:248-50.
    • (2001) Science , vol.293 , pp. 248-250
    • Fearon, D.T.1    Manders, P.2    Wagner, S.D.3
  • 82
    • 0042470566 scopus 로고    scopus 로고
    • Regulatory mechanisms that determine the development and function of plasma cells
    • Calame KL, Lin KI, Tunyaplin C. Regulatory mechanisms that determine the development and function of plasma cells. Ann Rev Immunol 2003; 21:205-30.
    • (2003) Ann Rev Immunol , vol.21 , pp. 205-230
    • Calame, K.L.1    Lin, K.I.2    Tunyaplin, C.3
  • 83
    • 0025176086 scopus 로고
    • Separation of events mediating B cell proliferation and Ig production by using T cell membranes and lymphokines
    • Hodgkin PD, Yamashita LC, Coffman RL, Kehry MR. Separation of events mediating B cell proliferation and Ig production by using T cell membranes and lymphokines. J Immunol 1990; 145:2025-34.
    • (1990) J Immunol , vol.145 , pp. 2025-2034
    • Hodgkin, P.D.1    Yamashita, L.C.2    Coffman, R.L.3    Kehry, M.R.4
  • 84
    • 0028921477 scopus 로고
    • Interleukin-6 in human multiple myeloma
    • Klein B, Zhang XG, Lu ZY, Bataille R. Interleukin-6 in human multiple myeloma. Blood 1995; 85:863-72.
    • (1995) Blood , vol.85 , pp. 863-872
    • Klein, B.1    Zhang, X.G.2    Lu, Z.Y.3    Bataille, R.4
  • 85
    • 0035869281 scopus 로고    scopus 로고
    • Interleukin-6 is a growth factor for nonmalignant human plasmablasts
    • Jego G, Bataille R, Pellat-Deceunynck C. Interleukin-6 is a growth factor for nonmalignant human plasmablasts. Blood 2001; 97:1817-22.
    • (2001) Blood , vol.97 , pp. 1817-1822
    • Jego, G.1    Bataille, R.2    Pellat-Deceunynck, C.3
  • 86
    • 0021968045 scopus 로고
    • Stimulation of in vitro immunoglobulin production by interferon-alpha
    • Neubauer RH, Goldstein L, Rabin H, Stebbing N. Stimulation of in vitro immunoglobulin production by interferon-alpha. J Immunol 1985; 134:299-304.
    • (1985) J Immunol , vol.134 , pp. 299-304
    • Neubauer, R.H.1    Goldstein, L.2    Rabin, H.3    Stebbing, N.4
  • 88
    • 0035030376 scopus 로고    scopus 로고
    • Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
    • Le Bon A, Schiavoni G, D'Agostino G, Gresser I, Belardelli F, Tough DF. Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 2001; 14:461-70.
    • (2001) Immunity , vol.14 , pp. 461-470
    • Le Bon, A.1    Schiavoni, G.2    D'Agostino, G.3    Gresser, I.4    Belardelli, F.5    Tough, D.F.6
  • 89
    • 0036518287 scopus 로고    scopus 로고
    • Mouse and human dendritic cell subtypes
    • Shortman K, Liu YJ. Mouse and human dendritic cell subtypes. Nat Rev Immunol 2002; 2:151-61.
    • (2002) Nat Rev Immunol , vol.2 , pp. 151-161
    • Shortman, K.1    Liu, Y.J.2
  • 90
    • 0041429619 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6
    • Jego G, Palucka AK, Blanck JP, Chalouni C, Pascual V, Banchereau J. Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. Immunity 2003; 19:225-34.
    • (2003) Immunity , vol.19 , pp. 225-234
    • Jego, G.1    Palucka, A.K.2    Blanck, J.P.3    Chalouni, C.4    Pascual, V.5    Banchereau, J.6
  • 91
    • 0036634390 scopus 로고    scopus 로고
    • BAFF. A fundamental survival factor for B cells
    • Mackay F, Browning JL. BAFF. A fundamental survival factor for B cells. Nat Immunol 2002; 2:465-75.
    • (2002) Nat Immunol , vol.2 , pp. 465-475
    • Mackay, F.1    Browning, J.L.2
  • 92
    • 0038142395 scopus 로고    scopus 로고
    • Macrophage and dendritic-cell dependent regulation of human B cell proliferation requires the TNF family ligand BAFF
    • Craxton A, Magaletti D, Ryan EJ, Clark EA. Macrophage and dendritic-cell dependent regulation of human B cell proliferation requires the TNF family ligand BAFF. Blood 2003; 101:4464-71.
    • (2003) Blood , vol.101 , pp. 4464-4471
    • Craxton, A.1    Magaletti, D.2    Ryan, E.J.3    Clark, E.A.4
  • 93
    • 0035908122 scopus 로고    scopus 로고
    • Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells
    • Kim CH, Rott LS, Clark-Lewis I, Campbell DJ, Wu L, Butcher EC. Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells. J Exp Med 2001; 193:1373-81.
    • (2001) J Exp Med , vol.193 , pp. 1373-1381
    • Kim, C.H.1    Rott, L.S.2    Clark-Lewis, I.3    Campbell, D.J.4    Wu, L.5    Butcher, E.C.6
  • 95
    • 0037087296 scopus 로고    scopus 로고
    • Cross-linking surface Ig delays CD40 ligand- and IL-4-induced B cell Ig class switching and reveals evidence for independent regulation of B cell proliferation and differentiation
    • Rush JS, Hasbold J, Hodgkin PD. Cross-linking surface Ig delays CD40 ligand- and IL-4-induced B cell Ig class switching and reveals evidence for independent regulation of B cell proliferation and differentiation. J Immunol 2002; 168:2676-82.
    • (2002) J Immunol , vol.168 , pp. 2676-2682
    • Rush, J.S.1    Hasbold, J.2    Hodgkin, P.D.3
  • 96
    • 0032534747 scopus 로고    scopus 로고
    • CD27/CD70 interaction augments IgE secretion by promoting the differentiation of memory B cells into plasma cells
    • Nagumo H, Agematsu K, Shinozaki K et al. CD27/CD70 interaction augments IgE secretion by promoting the differentiation of memory B cells into plasma cells. J Immunol 1998; 161:6496-50.
    • (1998) J Immunol , vol.161 , pp. 6496-6550
    • Nagumo, H.1    Agematsu, K.2    Shinozaki, K.3
  • 97
    • 0031975888 scopus 로고    scopus 로고
    • Generation of plasma cells from peripheral blood memory B cells: Synergistic effect of interleukin-10 and CD27/CD70 interaction
    • Agematsu K, Nagumo H, Oguchi Y et al. Generation of plasma cells from peripheral blood memory B cells: synergistic effect of interleukin-10 and CD27/CD70 interaction. Blood 1998; 91:173-80.
    • (1998) Blood , vol.91 , pp. 173-180
    • Agematsu, K.1    Nagumo, H.2    Oguchi, Y.3
  • 98
    • 0029046694 scopus 로고
    • Regulation of human B cell function by recombinant CD40 ligand and other TNF-related ligands
    • Jumper MD, Nishioka Y, Davis LS, Lipsky PE, Meek K. Regulation of human B cell function by recombinant CD40 ligand and other TNF-related ligands. J Immunol 1995; 155:2369-78.
    • (1995) J Immunol , vol.155 , pp. 2369-2378
    • Jumper, M.D.1    Nishioka, Y.2    Davis, L.S.3    Lipsky, P.E.4    Meek, K.5
  • 99
    • 0035851383 scopus 로고    scopus 로고
    • Acute and long-term effects of booster immunisation on frequencies of antigen-specific memory B-lymphocytes
    • Nanan R, Heinrich D, Frosch M, Kreth HW. Acute and long-term effects of booster immunisation on frequencies of antigen-specific memory B-lymphocytes. Vaccine 2001; 20:498-504.
    • (2001) Vaccine , vol.20 , pp. 498-504
    • Nanan, R.1    Heinrich, D.2    Frosch, M.3    Kreth, H.W.4
  • 100
    • 0029933507 scopus 로고    scopus 로고
    • Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation
    • Liu YJ, Malisan F, de Bouteiller O et al. Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation. Immunity 1996; 4:241-50.
    • (1996) Immunity , vol.4 , pp. 241-250
    • Liu, Y.J.1    Malisan, F.2    De Bouteiller, O.3
  • 102
    • 0023692791 scopus 로고
    • Is rapid proliferation in B centroblasts linked to somatic mutation in memory B cell clones?
    • Zhang J, MacLennan IC, Liu YJ, Lane PJ. Is rapid proliferation in B centroblasts linked to somatic mutation in memory B cell clones? Immunol Lett 1988; 18:297-9.
    • (1988) Immunol Lett , vol.18 , pp. 297-299
    • Zhang, J.1    MacLennan, I.C.2    Liu, Y.J.3    Lane, P.J.4
  • 103
    • 1842405428 scopus 로고    scopus 로고
    • Evidence for a large compartment of IgM-expressing memory B cells in humans
    • Klein U, Kuppers R, Rajewsky K. Evidence for a large compartment of IgM-expressing memory B cells in humans. Blood 1997; 89:1288-98.
    • (1997) Blood , vol.89 , pp. 1288-1298
    • Klein, U.1    Kuppers, R.2    Rajewsky, K.3
  • 105
    • 0029127069 scopus 로고
    • Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells
    • Dunn-Walters DK, Isaacson PG, Spencer J. Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells. J Exp Med 1995; 182:559-66.
    • (1995) J Exp Med , vol.182 , pp. 559-566
    • Dunn-Walters, D.K.1    Isaacson, P.G.2    Spencer, J.3
  • 106
    • 0034141730 scopus 로고    scopus 로고
    • Characteristics of human IgA and IgM genes used by plasma cells in the salivary gland resemble those used in duodenum but not those used in the spleen
    • Dunn-Walters DK, Hackett M, Boursier L, Ciclitira PJ, Morgan P, Challacombe SJ, Spencer J. Characteristics of human IgA and IgM genes used by plasma cells in the salivary gland resemble those used in duodenum but not those used in the spleen. J Immunol 2000; 164:1595-601.
    • (2000) J Immunol , vol.164 , pp. 1595-1601
    • Dunn-Walters, D.K.1    Hackett, M.2    Boursier, L.3    Ciclitira, P.J.4    Morgan, P.5    Challacombe, S.J.6    Spencer, J.7
  • 107
    • 0032588688 scopus 로고    scopus 로고
    • Characteristics of IgVH genes used by human intestinal plasma cells from childhood
    • Boursier L, Dunn-Walters DK, Spencer J. Characteristics of IgVH genes used by human intestinal plasma cells from childhood. Immunology 1999; 97:558-64.
    • (1999) Immunology , vol.97 , pp. 558-564
    • Boursier, L.1    Dunn-Walters, D.K.2    Spencer, J.3
  • 108
    • 0031031695 scopus 로고    scopus 로고
    • Memory B lymphocytes migrate to bone marrow in humans
    • Paramithiotis E, Cooper MD. Memory B lymphocytes migrate to bone marrow in humans. Proc Natl Acad Sci USA 1997; 94:208-12.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 208-212
    • Paramithiotis, E.1    Cooper, M.D.2
  • 109
    • 0028797387 scopus 로고
    • Memory B lymphocytes in human tonsil do not express surface IgD
    • Nicholson IC, Brisco MJ, Zola H. Memory B lymphocytes in human tonsil do not express surface IgD. J Immunol 1995; 154:1105-13.
    • (1995) J Immunol , vol.154 , pp. 1105-1113
    • Nicholson, I.C.1    Brisco, M.J.2    Zola, H.3
  • 110
    • 4043164158 scopus 로고    scopus 로고
    • Human blood IgM 'memory' B cells are circulating splenic marginal zone B cells harboring a pre-diversified immunoglobulin repertoire
    • DOI 10.1182/blood-2004-01-0346
    • Weller S, Braun MC, Tan BK et al. Human blood IgM 'memory' B cells are circulating splenic marginal zone B cells harboring a pre-diversified immunoglobulin repertoire. Blood 2004, DOI 10.1182/blood-2004-01-0346.
    • (2004) Blood
    • Weller, S.1    Braun, M.C.2    Tan, B.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.