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Volumn 271, Issue 1, 2016, Pages 230-245

Peyer's patches: Organizing B-cell responses at the intestinal frontier

Author keywords

Antibodies; B cells; Cell trafficking; Dendritic cells; Mucosa; Repertoire development

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN A ANTIBODY;

EID: 84963516373     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12400     Document Type: Article
Times cited : (225)

References (173)
  • 1
    • 0037622187 scopus 로고    scopus 로고
    • Role of secretory antibodies in the defence against infections
    • Brandtzaeg P. Role of secretory antibodies in the defence against infections. Int J Med Microbiol 2003;293:3-15.
    • (2003) Int J Med Microbiol , vol.293 , pp. 3-15
    • Brandtzaeg, P.1
  • 2
    • 84890336529 scopus 로고    scopus 로고
    • The gastrointestinal frontier: IgA and viruses
    • Blutt SE, Conner ME. The gastrointestinal frontier: IgA and viruses. Front Immunol 2013;4:402.
    • (2013) Front Immunol , vol.4 , pp. 402
    • Blutt, S.E.1    Conner, M.E.2
  • 3
    • 84939570686 scopus 로고    scopus 로고
    • The bilateral responsiveness between intestinal microbes and IgA
    • Macpherson AJ, Koller Y, McCoy KD. The bilateral responsiveness between intestinal microbes and IgA. Trends Immunol 2015;36:460-470.
    • (2015) Trends Immunol , vol.36 , pp. 460-470
    • Macpherson, A.J.1    Koller, Y.2    McCoy, K.D.3
  • 4
    • 77952311371 scopus 로고    scopus 로고
    • Adaptive immune regulation in the gut: T cell-dependent and T cell-independent IgA synthesis
    • Fagarasan S, Kawamoto S, Kanagawa O, Suzuki K. Adaptive immune regulation in the gut: T cell-dependent and T cell-independent IgA synthesis. Annu Rev Immunol 2010;28:243-273.
    • (2010) Annu Rev Immunol , vol.28 , pp. 243-273
    • Fagarasan, S.1    Kawamoto, S.2    Kanagawa, O.3    Suzuki, K.4
  • 7
    • 0001562712 scopus 로고
    • Peyer's patches in the human gut
    • Cornes JS. Peyer's patches in the human gut. Proc R Soc Med 1965;58:716.
    • (1965) Proc R Soc Med , vol.58 , pp. 716
    • Cornes, J.S.1
  • 9
    • 0026329353 scopus 로고
    • The preference for switching to IgA expression by Peyer's patch germinal center B cells is likely due to the intrinsic influence of their microenvironment
    • Weinstein PD, Cebra JJ. The preference for switching to IgA expression by Peyer's patch germinal center B cells is likely due to the intrinsic influence of their microenvironment. J Immunol 1991;147:4126-4135.
    • (1991) J Immunol , vol.147 , pp. 4126-4135
    • Weinstein, P.D.1    Cebra, J.J.2
  • 10
    • 77958157901 scopus 로고    scopus 로고
    • Sampling of the intestinal microbiota by epithelial M cells
    • Pickard JM, Chervonsky AV. Sampling of the intestinal microbiota by epithelial M cells. Curr Gastroenterol Rep 2010;12:331-339.
    • (2010) Curr Gastroenterol Rep , vol.12 , pp. 331-339
    • Pickard, J.M.1    Chervonsky, A.V.2
  • 11
    • 84898685253 scopus 로고    scopus 로고
    • Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses
    • Lecuyer E, et al. Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses. Immunity 2014;40:608-620.
    • (2014) Immunity , vol.40 , pp. 608-620
    • Lecuyer, E.1
  • 12
    • 77958125277 scopus 로고    scopus 로고
    • Cellular and molecular requirements in lymph node and Peyer's patch development
    • Coles M, Kioussis D, Veiga-Fernandes H. Cellular and molecular requirements in lymph node and Peyer's patch development. Prog Mol Biol Transl Sci 2010;92:177-205.
    • (2010) Prog Mol Biol Transl Sci , vol.92 , pp. 177-205
    • Coles, M.1    Kioussis, D.2    Veiga-Fernandes, H.3
  • 13
    • 77956175900 scopus 로고    scopus 로고
    • New insights into the development of lymphoid tissues
    • van de Pavert SA, Mebius RE. New insights into the development of lymphoid tissues. Nat Rev Immunol 2010;10:664-674.
    • (2010) Nat Rev Immunol , vol.10 , pp. 664-674
    • van de Pavert, S.A.1    Mebius, R.E.2
  • 14
    • 84864554059 scopus 로고    scopus 로고
    • Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems
    • Patel A, et al. Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems. Sci Signal 2012;5:ra55.
    • (2012) Sci Signal , vol.5 , pp. ra55
    • Patel, A.1
  • 15
    • 84923041629 scopus 로고    scopus 로고
    • Identification and distribution of developing innate lymphoid cells in the fetal mouse intestine
    • Bando JK, Liang HE, Locksley RM. Identification and distribution of developing innate lymphoid cells in the fetal mouse intestine. Nat Immunol 2015;16:153-160.
    • (2015) Nat Immunol , vol.16 , pp. 153-160
    • Bando, J.K.1    Liang, H.E.2    Locksley, R.M.3
  • 16
    • 84897480560 scopus 로고    scopus 로고
    • Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity
    • van de Pavert SA, et al. Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity. Nature 2014;508:123-127.
    • (2014) Nature , vol.508 , pp. 123-127
    • van de Pavert, S.A.1
  • 17
    • 84875452879 scopus 로고    scopus 로고
    • Peyer's patch inducer cells play a leading role in the formation of B and T cell zone architecture
    • Nakagawa R, Togawa A, Nagasawa T, Nishikawa S. Peyer's patch inducer cells play a leading role in the formation of B and T cell zone architecture. J Immunol 2013;190:3309-3318.
    • (2013) J Immunol , vol.190 , pp. 3309-3318
    • Nakagawa, R.1    Togawa, A.2    Nagasawa, T.3    Nishikawa, S.4
  • 18
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong YY, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999;397:315-323.
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.Y.1
  • 19
    • 34247605948 scopus 로고    scopus 로고
    • Lymphotoxin-independent expression of TNF-related activation-induced cytokine by stromal cells in cryptopatches, isolated lymphoid follicles, and Peyer's patches
    • Taylor RT, et al. Lymphotoxin-independent expression of TNF-related activation-induced cytokine by stromal cells in cryptopatches, isolated lymphoid follicles, and Peyer's patches. J Immunol 2007;178:5659-5667.
    • (2007) J Immunol , vol.178 , pp. 5659-5667
    • Taylor, R.T.1
  • 20
    • 84861475149 scopus 로고    scopus 로고
    • Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development
    • Sugiyama M, et al. Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development. Int Immunol 2012;24:369-378.
    • (2012) Int Immunol , vol.24 , pp. 369-378
    • Sugiyama, M.1
  • 21
    • 77950491661 scopus 로고    scopus 로고
    • RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium
    • Knoop KA, et al. RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium. J Immunol 2009;183:5738-5747.
    • (2009) J Immunol , vol.183 , pp. 5738-5747
    • Knoop, K.A.1
  • 22
    • 39649094515 scopus 로고    scopus 로고
    • Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function
    • Allen CD, Cyster JG. Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function. Semin Immunol 2008;20:14-25.
    • (2008) Semin Immunol , vol.20 , pp. 14-25
    • Allen, C.D.1    Cyster, J.G.2
  • 23
    • 84941638746 scopus 로고    scopus 로고
    • Dynamics of B cell migration to and within secondary lymphoid organs
    • Honjo T, Alt FW, Neuberger MS eds. London, UK: Elsevier Academic Press
    • Cyster JG, Von Andrian UH. Dynamics of B cell migration to and within secondary lymphoid organs. In: Honjo T, Alt FW, Neuberger MS eds. Molecular Biology of B cells. London, UK: Elsevier Academic Press, 2004:203-222.
    • (2004) Molecular Biology of B cells , pp. 203-222
    • Cyster, J.G.1    Von Andrian, U.H.2
  • 24
    • 0036645293 scopus 로고    scopus 로고
    • Chemokine requirements for B cell entry to lymph nodes and Peyer's patches
    • Okada T, et al. Chemokine requirements for B cell entry to lymph nodes and Peyer's patches. J Exp Med 2002;196:65-75.
    • (2002) J Exp Med , vol.196 , pp. 65-75
    • Okada, T.1
  • 25
    • 77954150116 scopus 로고    scopus 로고
    • Finding the right niche: B cell migration in the early phases of T-dependent antibody responses
    • Pereira JP, Kelly LM, Cyster JG. Finding the right niche: B cell migration in the early phases of T-dependent antibody responses. Int Immunol 2010;22:413-419.
    • (2010) Int Immunol , vol.22 , pp. 413-419
    • Pereira, J.P.1    Kelly, L.M.2    Cyster, J.G.3
  • 26
    • 69349087555 scopus 로고    scopus 로고
    • EBI2 mediates B cell segregation between the outer and centre follicle
    • Pereira JP, Kelly LM, Xu Y, Cyster JG. EBI2 mediates B cell segregation between the outer and centre follicle. Nature 2009;460:1122-1126.
    • (2009) Nature , vol.460 , pp. 1122-1126
    • Pereira, J.P.1    Kelly, L.M.2    Xu, Y.3    Cyster, J.G.4
  • 27
    • 68649108084 scopus 로고    scopus 로고
    • Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses
    • Gatto D, Paus D, Basten A, Mackay CR, Brink R. Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses. Immunity 2009;31:259-269.
    • (2009) Immunity , vol.31 , pp. 259-269
    • Gatto, D.1    Paus, D.2    Basten, A.3    Mackay, C.R.4    Brink, R.5
  • 28
    • 80053055261 scopus 로고    scopus 로고
    • EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues
    • Kelly LM, Pereira JP, Yi T, Xu Y, Cyster JG. EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues. J Immunol 2011;187:3026-3032.
    • (2011) J Immunol , vol.187 , pp. 3026-3032
    • Kelly, L.M.1    Pereira, J.P.2    Yi, T.3    Xu, Y.4    Cyster, J.G.5
  • 29
    • 84859729872 scopus 로고    scopus 로고
    • S1PR2 links germinal center confinement and growth regulation
    • Green JA, Cyster JG. S1PR2 links germinal center confinement and growth regulation. Immunol Rev 2012;247:36-51.
    • (2012) Immunol Rev , vol.247 , pp. 36-51
    • Green, J.A.1    Cyster, J.G.2
  • 30
    • 0033679107 scopus 로고    scopus 로고
    • CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue
    • Cook DN, et al. CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue. Immunity 2000;12:495-503.
    • (2000) Immunity , vol.12 , pp. 495-503
    • Cook, D.N.1
  • 31
    • 0035107851 scopus 로고    scopus 로고
    • CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses
    • Varona R, et al. CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses. J Clin Invest 2001;107:R37-R45.
    • (2001) J Clin Invest , vol.107 , pp. R37-R45
    • Varona, R.1
  • 32
    • 0042834355 scopus 로고    scopus 로고
    • + dendritic cells
    • + dendritic cells. J Immunol 2003;171:2797-2803.
    • (2003) J Immunol , vol.171 , pp. 2797-2803
    • Zhao, X.1
  • 33
    • 84864147310 scopus 로고    scopus 로고
    • The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells
    • Kanaya T, et al. The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells. Nat Immunol 2012;13:729-736.
    • (2012) Nat Immunol , vol.13 , pp. 729-736
    • Kanaya, T.1
  • 34
    • 29644439799 scopus 로고    scopus 로고
    • The membrane-bound chemokine CXCL16 expressed on follicle-associated epithelium and M cells mediates lympho-epithelial interaction in GALT
    • Hase K, et al. The membrane-bound chemokine CXCL16 expressed on follicle-associated epithelium and M cells mediates lympho-epithelial interaction in GALT. J Immunol 2006;176:43-51.
    • (2006) J Immunol , vol.176 , pp. 43-51
    • Hase, K.1
  • 35
    • 76149126108 scopus 로고    scopus 로고
    • Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning
    • Pham TH, et al. Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning. J Exp Med 2010;207:17-27.
    • (2010) J Exp Med , vol.207 , pp. 17-27
    • Pham, T.H.1
  • 36
    • 84859385704 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs
    • Cyster JG, Schwab SR. Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs. Annu Rev Immunol 2012;30:69-94.
    • (2012) Annu Rev Immunol , vol.30 , pp. 69-94
    • Cyster, J.G.1    Schwab, S.R.2
  • 37
    • 77954493923 scopus 로고    scopus 로고
    • + T lymphocytes circulate through lymphoid organs to interact with endogenous antigens and upregulate their function
    • + T lymphocytes circulate through lymphoid organs to interact with endogenous antigens and upregulate their function. J Immunol 2010;184:4646-4653.
    • (2010) J Immunol , vol.184 , pp. 4646-4653
    • Tomura, M.1    Itoh, K.2    Kanagawa, O.3
  • 38
    • 84880669087 scopus 로고    scopus 로고
    • CXCR4 promotes B cell egress from Peyer's patches
    • Schmidt TH, Bannard O, Gray EE, Cyster JG. CXCR4 promotes B cell egress from Peyer's patches. J Exp Med 2013;210:1099-1107.
    • (2013) J Exp Med , vol.210 , pp. 1099-1107
    • Schmidt, T.H.1    Bannard, O.2    Gray, E.E.3    Cyster, J.G.4
  • 39
    • 84902581437 scopus 로고    scopus 로고
    • Hypertrophy of infected Peyer's patches arises from global, interferon-receptor, and CD69-independent shutdown of lymphocyte egress
    • Schulz O, et al. Hypertrophy of infected Peyer's patches arises from global, interferon-receptor, and CD69-independent shutdown of lymphocyte egress. Mucosal Immunol 2014;7:892-904.
    • (2014) Mucosal Immunol , vol.7 , pp. 892-904
    • Schulz, O.1
  • 40
    • 33645289121 scopus 로고    scopus 로고
    • CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs
    • Shiow LR, et al. CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature 2006;440:540-544.
    • (2006) Nature , vol.440 , pp. 540-544
    • Shiow, L.R.1
  • 41
    • 84874563887 scopus 로고    scopus 로고
    • Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process
    • Yang CW, Unanue ER. Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process. J Exp Med 2013;210:375-387.
    • (2013) J Exp Med , vol.210 , pp. 375-387
    • Yang, C.W.1    Unanue, E.R.2
  • 42
    • 0030944142 scopus 로고    scopus 로고
    • Cords, channels, corridors and conduits: critical architectural elements facilitating cell interactions in the lymph node cortex
    • Gretz JE, Anderson AO, Shaw S. Cords, channels, corridors and conduits: critical architectural elements facilitating cell interactions in the lymph node cortex. Immunol Rev 1997;156:11-24.
    • (1997) Immunol Rev , vol.156 , pp. 11-24
    • Gretz, J.E.1    Anderson, A.O.2    Shaw, S.3
  • 44
    • 34548044827 scopus 로고    scopus 로고
    • Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells
    • Phan TG, Grigorova I, Okada T, Cyster JG. Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells. Nat Immunol 2007;8:992-1000.
    • (2007) Nat Immunol , vol.8 , pp. 992-1000
    • Phan, T.G.1    Grigorova, I.2    Okada, T.3    Cyster, J.G.4
  • 45
    • 77951298265 scopus 로고    scopus 로고
    • Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes
    • Gonzalez SF, et al. Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes. Nat Immunol 2010;11:427-434.
    • (2010) Nat Immunol , vol.11 , pp. 427-434
    • Gonzalez, S.F.1
  • 46
    • 84921269829 scopus 로고    scopus 로고
    • Strategically localized dendritic cells promote rapid T cell responses to lymph-borne particulate antigens
    • Gerner MY, Torabi-Parizi P, Germain RN. Strategically localized dendritic cells promote rapid T cell responses to lymph-borne particulate antigens. Immunity 2015;42:172-185.
    • (2015) Immunity , vol.42 , pp. 172-185
    • Gerner, M.Y.1    Torabi-Parizi, P.2    Germain, R.N.3
  • 47
    • 84856293017 scopus 로고    scopus 로고
    • Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization
    • Park C, Hwang IY, Sinha RK, Kamenyeva O, Davis MD, Kehrl JH. Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization. Blood 2012;119:978-989.
    • (2012) Blood , vol.119 , pp. 978-989
    • Park, C.1    Hwang, I.Y.2    Sinha, R.K.3    Kamenyeva, O.4    Davis, M.D.5    Kehrl, J.H.6
  • 48
    • 67650482967 scopus 로고    scopus 로고
    • Visualizing B cell capture of cognate antigen from follicular dendritic cells
    • Suzuki K, Grigorova I, Phan TG, Kelly L, Cyster JG. Visualizing B cell capture of cognate antigen from follicular dendritic cells. J Exp Med 2009;206:1485-1493.
    • (2009) J Exp Med , vol.206 , pp. 1485-1493
    • Suzuki, K.1    Grigorova, I.2    Phan, T.G.3    Kelly, L.4    Cyster, J.G.5
  • 49
    • 84903387500 scopus 로고    scopus 로고
    • Follicular dendritic cells: dynamic antigen libraries
    • Heesters BA, Myers RC, Carroll MC. Follicular dendritic cells: dynamic antigen libraries. Nat Rev Immunol 2014;14:495-504.
    • (2014) Nat Rev Immunol , vol.14 , pp. 495-504
    • Heesters, B.A.1    Myers, R.C.2    Carroll, M.C.3
  • 50
    • 0030000550 scopus 로고    scopus 로고
    • Antigen sampling across epithelial barriers and induction of mucosal immune responses
    • Neutra MR, Pringault E, Kraehenbuhl JP. Antigen sampling across epithelial barriers and induction of mucosal immune responses. Annu Rev Immunol 1996;14:275-300.
    • (1996) Annu Rev Immunol , vol.14 , pp. 275-300
    • Neutra, M.R.1    Pringault, E.2    Kraehenbuhl, J.P.3
  • 51
    • 0032794570 scopus 로고    scopus 로고
    • Uptake and transport of intestinal macromolecules and microorganisms by M cells in Peyer's patches - a personal and historical perspective
    • Owen RL. Uptake and transport of intestinal macromolecules and microorganisms by M cells in Peyer's patches - a personal and historical perspective. Semin Immunol 1999;11:157-163.
    • (1999) Semin Immunol , vol.11 , pp. 157-163
    • Owen, R.L.1
  • 52
    • 0035174046 scopus 로고    scopus 로고
    • Collaboration of epithelial cells with organized mucosal lymphoid tissues
    • Neutra MR, Mantis NJ, Kraehenbuhl JP. Collaboration of epithelial cells with organized mucosal lymphoid tissues. Nat Immunol 2001;2:1004-1009.
    • (2001) Nat Immunol , vol.2 , pp. 1004-1009
    • Neutra, M.R.1    Mantis, N.J.2    Kraehenbuhl, J.P.3
  • 53
    • 84941647683 scopus 로고    scopus 로고
    • BALB/c and C57BL/6 mice differ in polyreactive IgA abundance, which impacts the generation of antigen-specific IgA and microbiota diversity
    • Fransen F, et al. BALB/c and C57BL/6 mice differ in polyreactive IgA abundance, which impacts the generation of antigen-specific IgA and microbiota diversity. Immunity 2015;43:527-540.
    • (2015) Immunity , vol.43 , pp. 527-540
    • Fransen, F.1
  • 54
    • 38849145753 scopus 로고    scopus 로고
    • Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment
    • Kadaoui KA, Corthesy B. Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment. J Immunol 2007;179:7751-7757.
    • (2007) J Immunol , vol.179 , pp. 7751-7757
    • Kadaoui, K.A.1    Corthesy, B.2
  • 55
    • 84884580565 scopus 로고    scopus 로고
    • Dectin-1 is essential for reverse transcytosis of glycosylated SIgA-antigen complexes by intestinal M cells
    • Rochereau N, et al. Dectin-1 is essential for reverse transcytosis of glycosylated SIgA-antigen complexes by intestinal M cells. PLoS Biol 2013;11:e1001658.
    • (2013) PLoS Biol , vol.11 , pp. e1001658
    • Rochereau, N.1
  • 56
    • 70449653428 scopus 로고    scopus 로고
    • Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response
    • Hase K, et al. Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response. Nature 2009;462:226-230.
    • (2009) Nature , vol.462 , pp. 226-230
    • Hase, K.1
  • 57
    • 0023092367 scopus 로고
    • Transport of membrane-bound macromolecules by M cells in follicle-associated epithelium of rabbit Peyer's patch
    • Neutra MR, Phillips TL, Mayer EL, Fishkind DJ. Transport of membrane-bound macromolecules by M cells in follicle-associated epithelium of rabbit Peyer's patch. Cell Tissue Res 1987;247:537-546.
    • (1987) Cell Tissue Res , vol.247 , pp. 537-546
    • Neutra, M.R.1    Phillips, T.L.2    Mayer, E.L.3    Fishkind, D.J.4
  • 58
    • 0028051751 scopus 로고
    • Heterogeneity of M-cell-associated B and T cells in human Peyer's patches
    • Farstad IN, Halstensen TS, Fausa O, Brandtzaeg P. Heterogeneity of M-cell-associated B and T cells in human Peyer's patches. Immunology 1994;83:457-464.
    • (1994) Immunology , vol.83 , pp. 457-464
    • Farstad, I.N.1    Halstensen, T.S.2    Fausa, O.3    Brandtzaeg, P.4
  • 59
    • 1542784504 scopus 로고    scopus 로고
    • Antigen transport into Peyer's patches: increased uptake by constant numbers of M cells
    • Gebert A, Steinmetz I, Fassbender S, Wendlandt KH. Antigen transport into Peyer's patches: increased uptake by constant numbers of M cells. Am J Pathol 2004;164:65-72.
    • (2004) Am J Pathol , vol.164 , pp. 65-72
    • Gebert, A.1    Steinmetz, I.2    Fassbender, S.3    Wendlandt, K.H.4
  • 60
    • 81455131800 scopus 로고    scopus 로고
    • Convergent and divergent development among M cell lineages in mouse mucosal epithelium
    • Wang J, Gusti V, Saraswati A, Lo DD. Convergent and divergent development among M cell lineages in mouse mucosal epithelium. J Immunol 2011;187:5277-5285.
    • (2011) J Immunol , vol.187 , pp. 5277-5285
    • Wang, J.1    Gusti, V.2    Saraswati, A.3    Lo, D.D.4
  • 61
    • 33646037701 scopus 로고    scopus 로고
    • TLRs regulate the gatekeeping functions of the intestinal follicle-associated epithelium
    • Chabot S, Wagner JS, Farrant S, Neutra MR. TLRs regulate the gatekeeping functions of the intestinal follicle-associated epithelium. J Immunol 2006;176:4275-4283.
    • (2006) J Immunol , vol.176 , pp. 4275-4283
    • Chabot, S.1    Wagner, J.S.2    Farrant, S.3    Neutra, M.R.4
  • 62
    • 0035871705 scopus 로고    scopus 로고
    • +, and double-negative Peyer's patch dendritic cells
    • +, and double-negative Peyer's patch dendritic cells. J Immunol 2001;166:4884-4890.
    • (2001) J Immunol , vol.166 , pp. 4884-4890
    • Iwasaki, A.1    Kelsall, B.L.2
  • 63
    • 79953301149 scopus 로고    scopus 로고
    • CCR6hiCD11c(int) B cells promote M-cell differentiation in Peyer's patch
    • Ebisawa M, et al. CCR6hiCD11c(int) B cells promote M-cell differentiation in Peyer's patch. Int Immunol 2011;23:261-269.
    • (2011) Int Immunol , vol.23 , pp. 261-269
    • Ebisawa, M.1
  • 64
    • 0030067796 scopus 로고    scopus 로고
    • Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyer's patch
    • Kelsall BL, Strober W. Distinct populations of dendritic cells are present in the subepithelial dome and T cell regions of the murine Peyer's patch. J Exp Med 1996;183:237-247.
    • (1996) J Exp Med , vol.183 , pp. 237-247
    • Kelsall, B.L.1    Strober, W.2
  • 66
    • 72249087932 scopus 로고    scopus 로고
    • Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme
    • Lelouard H, et al. Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme. Gastroenterology 2010;138(173-184):e171-e173.
    • (2010) Gastroenterology , vol.138 , Issue.173-184 , pp. e171-e173
    • Lelouard, H.1
  • 67
    • 3242794249 scopus 로고    scopus 로고
    • Peyer's patch dendritic cells process viral antigen from apoptotic epithelial cells in the intestine of reovirus-infected mice
    • Fleeton MN, Contractor N, Leon F, Wetzel JD, Dermody TS, Kelsall BL. Peyer's patch dendritic cells process viral antigen from apoptotic epithelial cells in the intestine of reovirus-infected mice. J Exp Med 2004;200:235-245.
    • (2004) J Exp Med , vol.200 , pp. 235-245
    • Fleeton, M.N.1    Contractor, N.2    Leon, F.3    Wetzel, J.D.4    Dermody, T.S.5    Kelsall, B.L.6
  • 68
    • 0034614894 scopus 로고    scopus 로고
    • A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes
    • Huang FP, et al. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J Exp Med 2000;191:435-444.
    • (2000) J Exp Med , vol.191 , pp. 435-444
    • Huang, F.P.1
  • 69
    • 84942543771 scopus 로고    scopus 로고
    • Sampling of Candida albicans and Candida tropicalis by Langerin-positive dendritic cells in mouse Peyer's patches
    • De Jesus M, Rodriguez AE, Yagita H, Ostroff GR, Mantis NJ. Sampling of Candida albicans and Candida tropicalis by Langerin-positive dendritic cells in mouse Peyer's patches. Immunol Lett 2015;168:64-72.
    • (2015) Immunol Lett , vol.168 , pp. 64-72
    • De Jesus, M.1    Rodriguez, A.E.2    Yagita, H.3    Ostroff, G.R.4    Mantis, N.J.5
  • 70
    • 84855290942 scopus 로고    scopus 로고
    • Prion uptake in the gut: identification of the first uptake and replication sites
    • Kujala P, et al. Prion uptake in the gut: identification of the first uptake and replication sites. PLoS Pathog 2011;7:e1002449.
    • (2011) PLoS Pathog , vol.7 , pp. e1002449
    • Kujala, P.1
  • 71
    • 0017341263 scopus 로고
    • Sequential uptake of horseradish peroxidase by lymphoid follicle epithelium of Peyer's patches in the normal unobstructed mouse intestine: an ultrastructural study
    • Owen RL. Sequential uptake of horseradish peroxidase by lymphoid follicle epithelium of Peyer's patches in the normal unobstructed mouse intestine: an ultrastructural study. Gastroenterology 1977;72:440-451.
    • (1977) Gastroenterology , vol.72 , pp. 440-451
    • Owen, R.L.1
  • 72
    • 34247149876 scopus 로고    scopus 로고
    • The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles
    • Pape KA, Catron DM, Itano AA, Jenkins MK. The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles. Immunity 2007;26:491-502.
    • (2007) Immunity , vol.26 , pp. 491-502
    • Pape, K.A.1    Catron, D.M.2    Itano, A.A.3    Jenkins, M.K.4
  • 73
    • 78650542647 scopus 로고    scopus 로고
    • Lymph node cortical sinus organization and relationship to lymphocyte egress dynamics and antigen exposure
    • Grigorova IL, Panteleev M, Cyster JG. Lymph node cortical sinus organization and relationship to lymphocyte egress dynamics and antigen exposure. Proc Natl Acad Sci USA 2010;107:20447-20452.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 20447-20452
    • Grigorova, I.L.1    Panteleev, M.2    Cyster, J.G.3
  • 74
    • 77951626546 scopus 로고    scopus 로고
    • A protease-dependent mechanism for initiating T-dependent B cell responses to large particulate antigens
    • Catron DM, Pape KA, Fife BT, van Rooijen N, Jenkins MK. A protease-dependent mechanism for initiating T-dependent B cell responses to large particulate antigens. J Immunol 2010;184:3609-3617.
    • (2010) J Immunol , vol.184 , pp. 3609-3617
    • Catron, D.M.1    Pape, K.A.2    Fife, B.T.3    van Rooijen, N.4    Jenkins, M.K.5
  • 75
    • 0019459618 scopus 로고
    • Mouse c1q: light and electron microscopic immunohistochemical localization
    • McManus LM, Nakane PK. Mouse c1q: light and electron microscopic immunohistochemical localization. J Immunol 1981;126:1421-1427.
    • (1981) J Immunol , vol.126 , pp. 1421-1427
    • McManus, L.M.1    Nakane, P.K.2
  • 76
    • 0036788363 scopus 로고    scopus 로고
    • Appearance and phenotype of murine follicular dendritic cells expressing VCAM-1
    • Balogh P, Aydar Y, Tew JG, Szakal AK. Appearance and phenotype of murine follicular dendritic cells expressing VCAM-1. Anat Rec 2002;268:160-168.
    • (2002) Anat Rec , vol.268 , pp. 160-168
    • Balogh, P.1    Aydar, Y.2    Tew, J.G.3    Szakal, A.K.4
  • 77
    • 0026750861 scopus 로고
    • Complement activation in the follicular light zone of human lymphoid tissues
    • Yamakawa M, Imai Y. Complement activation in the follicular light zone of human lymphoid tissues. Immunology 1992;76:378-384.
    • (1992) Immunology , vol.76 , pp. 378-384
    • Yamakawa, M.1    Imai, Y.2
  • 78
    • 0025334863 scopus 로고
    • Transfer of carbonic anhydrase-positive particles from the follicle-associated epithelium to lymphocytes of Peyer's patches in foetal sheep and lambs
    • Landsverk T, Trevella W, Nicander L. Transfer of carbonic anhydrase-positive particles from the follicle-associated epithelium to lymphocytes of Peyer's patches in foetal sheep and lambs. Cell Tissue Res 1990;261:239-247.
    • (1990) Cell Tissue Res , vol.261 , pp. 239-247
    • Landsverk, T.1    Trevella, W.2    Nicander, L.3
  • 79
    • 84935085624 scopus 로고    scopus 로고
    • Emerging and novel functions of complement protein C1q
    • Kouser L, et al. Emerging and novel functions of complement protein C1q. Front Immunol 2015;6:317.
    • (2015) Front Immunol , vol.6 , pp. 317
    • Kouser, L.1
  • 80
    • 84912032793 scopus 로고    scopus 로고
    • Increased serum IgA in Fcalpha/muR-deficient mice on the (129 x C57BL/6) F1 genetic background
    • Kurita N, Honda S, Shibuya A. Increased serum IgA in Fcalpha/muR-deficient mice on the (129 x C57BL/6) F1 genetic background. Mol Immunol 2015;63:367-372.
    • (2015) Mol Immunol , vol.63 , pp. 367-372
    • Kurita, N.1    Honda, S.2    Shibuya, A.3
  • 81
    • 67650457413 scopus 로고    scopus 로고
    • Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice
    • Honda S, et al. Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice. Proc Natl Acad Sci USA 2009;106:11230-11235.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11230-11235
    • Honda, S.1
  • 82
    • 0031570407 scopus 로고    scopus 로고
    • Specialization of mucosal follicular dendritic cells revealed by mucosal addressin-cell adhesion molecule-1 display
    • Szabo MC, Butcher EC, McEvoy LM. Specialization of mucosal follicular dendritic cells revealed by mucosal addressin-cell adhesion molecule-1 display. J Immunol 1997;158:5584-5588.
    • (1997) J Immunol , vol.158 , pp. 5584-5588
    • Szabo, M.C.1    Butcher, E.C.2    McEvoy, L.M.3
  • 83
    • 84902955284 scopus 로고    scopus 로고
    • Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitness
    • Wang X, Rodda LB, Bannard O, Cyster JG. Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitness. J Immunol 2014;192:4601-4609.
    • (2014) J Immunol , vol.192 , pp. 4601-4609
    • Wang, X.1    Rodda, L.B.2    Bannard, O.3    Cyster, J.G.4
  • 84
    • 0015097333 scopus 로고
    • Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit
    • Craig SW, Cebra JJ. Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit. J Exp Med 1971;134:188-200.
    • (1971) J Exp Med , vol.134 , pp. 188-200
    • Craig, S.W.1    Cebra, J.J.2
  • 85
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 2000;102:553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 86
    • 0033566828 scopus 로고    scopus 로고
    • Partial IgA-deficiency with increased Th2-type cytokines in TGF-beta 1 knockout mice
    • van Ginkel FW, et al. Partial IgA-deficiency with increased Th2-type cytokines in TGF-beta 1 knockout mice. J Immunol 1999;163:1951-1957.
    • (1999) J Immunol , vol.163 , pp. 1951-1957
    • van Ginkel, F.W.1
  • 87
    • 0033697670 scopus 로고    scopus 로고
    • TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo
    • Cazac BB, Roes J. TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo. Immunity 2000;13:443-451.
    • (2000) Immunity , vol.13 , pp. 443-451
    • Cazac, B.B.1    Roes, J.2
  • 88
    • 4344623276 scopus 로고    scopus 로고
    • TGF-beta receptor signaling is critical for mucosal IgA responses
    • Borsutzky S, Cazac BB, Roes J, Guzman CA. TGF-beta receptor signaling is critical for mucosal IgA responses. J Immunol 2004;173:3305-3309.
    • (2004) J Immunol , vol.173 , pp. 3305-3309
    • Borsutzky, S.1    Cazac, B.B.2    Roes, J.3    Guzman, C.A.4
  • 89
    • 50949128658 scopus 로고    scopus 로고
    • Cell intrinsic TGF-beta 1 regulation of B cells
    • Gros MJ, Naquet P, Guinamard RR. Cell intrinsic TGF-beta 1 regulation of B cells. J Immunol 2008;180:8153-8158.
    • (2008) J Immunol , vol.180 , pp. 8153-8158
    • Gros, M.J.1    Naquet, P.2    Guinamard, R.R.3
  • 90
    • 77954898661 scopus 로고    scopus 로고
    • The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut
    • Suzuki K, et al. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity 2010;33:71-83.
    • (2010) Immunity , vol.33 , pp. 71-83
    • Suzuki, K.1
  • 91
    • 34548208943 scopus 로고    scopus 로고
    • Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice
    • Travis MA, et al. Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice. Nature 2007;449:361-365.
    • (2007) Nature , vol.449 , pp. 361-365
    • Travis, M.A.1
  • 92
    • 34548176272 scopus 로고    scopus 로고
    • Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells
    • Tezuka H, et al. Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells. Nature 2007;448:929-933.
    • (2007) Nature , vol.448 , pp. 929-933
    • Tezuka, H.1
  • 93
    • 1642332951 scopus 로고    scopus 로고
    • Impaired IgA class switching in APRIL-deficient mice
    • Castigli E, et al. Impaired IgA class switching in APRIL-deficient mice. Proc Natl Acad Sci USA 2004;101:3903-3908.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3903-3908
    • Castigli, E.1
  • 94
    • 35348904427 scopus 로고    scopus 로고
    • TACI, isotype switching, CVID and IgAD
    • Castigli E, Geha RS. TACI, isotype switching, CVID and IgAD. Immunol Res 2007;38:102-111.
    • (2007) Immunol Res , vol.38 , pp. 102-111
    • Castigli, E.1    Geha, R.S.2
  • 95
    • 49749150027 scopus 로고    scopus 로고
    • Intestinal bacteria condition dendritic cells to promote IgA production
    • Massacand JC, et al. Intestinal bacteria condition dendritic cells to promote IgA production. PLoS ONE 2008;3:e2588.
    • (2008) PLoS ONE , vol.3 , pp. e2588
    • Massacand, J.C.1
  • 96
    • 34250205694 scopus 로고    scopus 로고
    • Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL
    • He B, et al. Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity 2007;26:812-826.
    • (2007) Immunity , vol.26 , pp. 812-826
    • He, B.1
  • 97
    • 80053429073 scopus 로고    scopus 로고
    • Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy
    • McCarthy DD, et al. Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy. J Clin Invest 2011;121:3991-4002.
    • (2011) J Clin Invest , vol.121 , pp. 3991-4002
    • McCarthy, D.D.1
  • 98
    • 0035860559 scopus 로고    scopus 로고
    • An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
    • Schiemann B, et al. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 2001;293:2111-2114.
    • (2001) Science , vol.293 , pp. 2111-2114
    • Schiemann, B.1
  • 99
    • 4043075603 scopus 로고    scopus 로고
    • TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology
    • Sasaki Y, Casola S, Kutok JL, Rajewsky K, Schmidt-Supprian M. TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology. J Immunol 2004;173:2245-2252.
    • (2004) J Immunol , vol.173 , pp. 2245-2252
    • Sasaki, Y.1    Casola, S.2    Kutok, J.L.3    Rajewsky, K.4    Schmidt-Supprian, M.5
  • 100
    • 69549128384 scopus 로고    scopus 로고
    • B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans
    • Warnatz K, et al. B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans. Proc Natl Acad Sci USA 2009;106:13945-13950.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13945-13950
    • Warnatz, K.1
  • 101
    • 33751223544 scopus 로고    scopus 로고
    • Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
    • Mora JR, et al. Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells. Science 2006;314:1157-1160.
    • (2006) Science , vol.314 , pp. 1157-1160
    • Mora, J.R.1
  • 102
    • 84938930412 scopus 로고    scopus 로고
    • Cutting edge: retinoic acid signaling in B cells is essential for oral immunization and microflora composition
    • Pantazi E, Marks E, Stolarczyk E, Lycke N, Noelle RJ, Elgueta R. Cutting edge: retinoic acid signaling in B cells is essential for oral immunization and microflora composition. J Immunol 2015;195:1368-1371.
    • (2015) J Immunol , vol.195 , pp. 1368-1371
    • Pantazi, E.1    Marks, E.2    Stolarczyk, E.3    Lycke, N.4    Noelle, R.J.5    Elgueta, R.6
  • 103
    • 79959921794 scopus 로고    scopus 로고
    • MyD88 and retinoic acid signaling pathways interact to modulate gastrointestinal activities of dendritic cells
    • Villablanca EJ, et al. MyD88 and retinoic acid signaling pathways interact to modulate gastrointestinal activities of dendritic cells. Gastroenterology 2011;141:176-185.
    • (2011) Gastroenterology , vol.141 , pp. 176-185
    • Villablanca, E.J.1
  • 104
    • 77951639699 scopus 로고    scopus 로고
    • T cell-independent IgA class switch recombination is restricted to the GALT and occurs prior to manifest germinal center formation
    • Bergqvist P, Stensson A, Lycke NY, Bemark M. T cell-independent IgA class switch recombination is restricted to the GALT and occurs prior to manifest germinal center formation. J Immunol 2010;184:3545-3553.
    • (2010) J Immunol , vol.184 , pp. 3545-3553
    • Bergqvist, P.1    Stensson, A.2    Lycke, N.Y.3    Bemark, M.4
  • 105
    • 79952287439 scopus 로고    scopus 로고
    • IgA-producing plasma cells originate from germinal centers that are induced by B-cell receptor engagement in humans
    • Barone F, et al. IgA-producing plasma cells originate from germinal centers that are induced by B-cell receptor engagement in humans. Gastroenterology 2011;140:947-956.
    • (2011) Gastroenterology , vol.140 , pp. 947-956
    • Barone, F.1
  • 106
    • 79955494239 scopus 로고    scopus 로고
    • + plasmablasts in the human gut are antigen-specific
    • + plasmablasts in the human gut are antigen-specific. J Clin Invest 2011;121:1946-1955.
    • (2011) J Clin Invest , vol.121 , pp. 1946-1955
    • Benckert, J.1
  • 107
    • 84856477029 scopus 로고    scopus 로고
    • Induction of gut IgA production through T cell-dependent and T cell-independent pathways
    • Bemark M, Boysen P, Lycke NY. Induction of gut IgA production through T cell-dependent and T cell-independent pathways. Ann N Y Acad Sci 2012;1247:97-116.
    • (2012) Ann N Y Acad Sci , vol.1247 , pp. 97-116
    • Bemark, M.1    Boysen, P.2    Lycke, N.Y.3
  • 108
    • 33751577786 scopus 로고    scopus 로고
    • Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers
    • Bergqvist P, Gardby E, Stensson A, Bemark M, Lycke NY. Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers. J Immunol 2006;177:7772-7783.
    • (2006) J Immunol , vol.177 , pp. 7772-7783
    • Bergqvist, P.1    Gardby, E.2    Stensson, A.3    Bemark, M.4    Lycke, N.Y.5
  • 109
    • 84902581045 scopus 로고    scopus 로고
    • Intestinal IgA production and its role in host-microbe interaction
    • Gutzeit C, Magri G, Cerutti A. Intestinal IgA production and its role in host-microbe interaction. Immunol Rev 2014;260:76-85.
    • (2014) Immunol Rev , vol.260 , pp. 76-85
    • Gutzeit, C.1    Magri, G.2    Cerutti, A.3
  • 111
  • 112
    • 84941659588 scopus 로고    scopus 로고
    • Innate and adaptive humoral responses coat distinct commensal bacteria with immunoglobulin A
    • Bunker JJ, et al. Innate and adaptive humoral responses coat distinct commensal bacteria with immunoglobulin A. Immunity 2015;43:541-553.
    • (2015) Immunity , vol.43 , pp. 541-553
    • Bunker, J.J.1
  • 113
    • 78751690647 scopus 로고    scopus 로고
    • Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion
    • Morita R, et al. Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity 2011;34:108-121.
    • (2011) Immunity , vol.34 , pp. 108-121
    • Morita, R.1
  • 115
    • 65549098748 scopus 로고    scopus 로고
    • IL-21 ensures TGF-beta 1-induced IgA isotype expression in mouse Peyer's patches
    • Seo GY, Youn J, Kim PH. IL-21 ensures TGF-beta 1-induced IgA isotype expression in mouse Peyer's patches. J Leukoc Biol 2009;85:744-750.
    • (2009) J Leukoc Biol , vol.85 , pp. 744-750
    • Seo, G.Y.1    Youn, J.2    Kim, P.H.3
  • 116
    • 58149242530 scopus 로고    scopus 로고
    • A T cell-dependent mechanism for the induction of human mucosal homing immunoglobulin A-secreting plasmablasts
    • Dullaers M, et al. A T cell-dependent mechanism for the induction of human mucosal homing immunoglobulin A-secreting plasmablasts. Immunity 2009;30:120-129.
    • (2009) Immunity , vol.30 , pp. 120-129
    • Dullaers, M.1
  • 117
    • 79951602552 scopus 로고    scopus 로고
    • Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense
    • Wei M, Shinkura R, Doi Y, Maruya M, Fagarasan S, Honjo T. Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense. Nat Immunol 2011;12:264-270.
    • (2011) Nat Immunol , vol.12 , pp. 264-270
    • Wei, M.1    Shinkura, R.2    Doi, Y.3    Maruya, M.4    Fagarasan, S.5    Honjo, T.6
  • 118
    • 84860123211 scopus 로고    scopus 로고
    • The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut
    • Kawamoto S, et al. The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science 2012;336:485-489.
    • (2012) Science , vol.336 , pp. 485-489
    • Kawamoto, S.1
  • 119
    • 56749146467 scopus 로고    scopus 로고
    • Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
    • Bouskra D, et al. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 2008;456:507-510.
    • (2008) Nature , vol.456 , pp. 507-510
    • Bouskra, D.1
  • 120
    • 48749091530 scopus 로고    scopus 로고
    • Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut
    • Tsuji M, et al. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity 2008;29:261-271.
    • (2008) Immunity , vol.29 , pp. 261-271
    • Tsuji, M.1
  • 121
    • 34249108271 scopus 로고    scopus 로고
    • Regulation of AID expression in the immune response
    • Crouch EE, et al. Regulation of AID expression in the immune response. J Exp Med 2007;204:1145-1156.
    • (2007) J Exp Med , vol.204 , pp. 1145-1156
    • Crouch, E.E.1
  • 122
    • 0035846113 scopus 로고    scopus 로고
    • In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
    • Fagarasan S, Kinoshita K, Muramatsu M, Ikuta K, Honjo T. In situ class switching and differentiation to IgA-producing cells in the gut lamina propria. Nature 2001;413:639-643.
    • (2001) Nature , vol.413 , pp. 639-643
    • Fagarasan, S.1    Kinoshita, K.2    Muramatsu, M.3    Ikuta, K.4    Honjo, T.5
  • 123
    • 2442479518 scopus 로고    scopus 로고
    • IgA class switch occurs in the organized nasopharynx- and gut-associated lymphoid tissue, but not in the diffuse lamina propria of airways and gut
    • Shikina T, et al. IgA class switch occurs in the organized nasopharynx- and gut-associated lymphoid tissue, but not in the diffuse lamina propria of airways and gut. J Immunol 2004;172:6259-6264.
    • (2004) J Immunol , vol.172 , pp. 6259-6264
    • Shikina, T.1
  • 124
    • 84890233027 scopus 로고    scopus 로고
    • Germinal center centroblasts transition to a centrocyte phenotype according to a timed program and depend on the dark zone for effective selection
    • Bannard O, Horton RM, Allen CD, An J, Nagasawa T, Cyster JG. Germinal center centroblasts transition to a centrocyte phenotype according to a timed program and depend on the dark zone for effective selection. Immunity 2013;39:912-924.
    • (2013) Immunity , vol.39 , pp. 912-924
    • Bannard, O.1    Horton, R.M.2    Allen, C.D.3    An, J.4    Nagasawa, T.5    Cyster, J.G.6
  • 125
    • 84958618864 scopus 로고    scopus 로고
    • Phenotypic and morphological properties of germinal center dark zone Cxcl12-expressing reticular cells
    • Rodda LB, Bannard O, Ludewig B, Nagasawa T, Cyster JG. Phenotypic and morphological properties of germinal center dark zone Cxcl12-expressing reticular cells. J Immunol 2015;195:4781-4791.
    • (2015) J Immunol , vol.195 , pp. 4781-4791
    • Rodda, L.B.1    Bannard, O.2    Ludewig, B.3    Nagasawa, T.4    Cyster, J.G.5
  • 126
    • 84874218199 scopus 로고    scopus 로고
    • The role of Peyer's patches in synchronizing gut IgA responses
    • Lycke NY, Bemark M. The role of Peyer's patches in synchronizing gut IgA responses. Front Immunol 2012;3:329.
    • (2012) Front Immunol , vol.3 , pp. 329
    • Lycke, N.Y.1    Bemark, M.2
  • 127
    • 0034694086 scopus 로고    scopus 로고
    • Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity
    • Bemark M, Sale JE, Kim HJ, Berek C, Cosgrove RA, Neuberger MS. Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity. J Exp Med 2000;192:1509-1514.
    • (2000) J Exp Med , vol.192 , pp. 1509-1514
    • Bemark, M.1    Sale, J.E.2    Kim, H.J.3    Berek, C.4    Cosgrove, R.A.5    Neuberger, M.S.6
  • 128
    • 1542377328 scopus 로고    scopus 로고
    • B cell receptor signal strength determines B cell fate
    • Casola S, et al. B cell receptor signal strength determines B cell fate. Nat Immunol 2004;5:317-327.
    • (2004) Nat Immunol , vol.5 , pp. 317-327
    • Casola, S.1
  • 129
    • 33749168166 scopus 로고    scopus 로고
    • B cell recruitment and selection in mouse GALT germinal centers
    • Casola S, Rajewsky K. B cell recruitment and selection in mouse GALT germinal centers. Curr Top Microbiol Immunol 2006;308:155-171.
    • (2006) Curr Top Microbiol Immunol , vol.308 , pp. 155-171
    • Casola, S.1    Rajewsky, K.2
  • 130
    • 84947728969 scopus 로고    scopus 로고
    • Sequence-intrinsic mechanisms that target AID mutational outcomes on antibody genes
    • Yeap L, et al. Sequence-intrinsic mechanisms that target AID mutational outcomes on antibody genes. Cell 2015;163:1124-1137.
    • (2015) Cell , vol.163 , pp. 1124-1137
    • Yeap, L.1
  • 131
    • 84937814800 scopus 로고    scopus 로고
    • Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota
    • Lindner C, et al. Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota. Nat Immunol 2015;16:880-888.
    • (2015) Nat Immunol , vol.16 , pp. 880-888
    • Lindner, C.1
  • 133
    • 84914142170 scopus 로고    scopus 로고
    • Intestinal bacteria and development of the antibody repertoire
    • Lanning DK, Knight KL. Intestinal bacteria and development of the antibody repertoire. Discov Med 2005;5:393-398.
    • (2005) Discov Med , vol.5 , pp. 393-398
    • Lanning, D.K.1    Knight, K.L.2
  • 134
    • 33646560027 scopus 로고    scopus 로고
    • The sheep and cattle Peyer's patch as a site of B-cell development
    • Yasuda M, Jenne CN, Kennedy LJ, Reynolds JD. The sheep and cattle Peyer's patch as a site of B-cell development. Vet Res 2006;37:401-415.
    • (2006) Vet Res , vol.37 , pp. 401-415
    • Yasuda, M.1    Jenne, C.N.2    Kennedy, L.J.3    Reynolds, J.D.4
  • 135
    • 84871660116 scopus 로고    scopus 로고
    • Diversification of the primary antibody repertoire begins during early follicle development in the rabbit appendix
    • Zhai SK, Lanning DK. Diversification of the primary antibody repertoire begins during early follicle development in the rabbit appendix. Mol Immunol 2013;54:140-147.
    • (2013) Mol Immunol , vol.54 , pp. 140-147
    • Zhai, S.K.1    Lanning, D.K.2
  • 136
    • 45149104972 scopus 로고    scopus 로고
    • + B cell repertoire in infants
    • + B cell repertoire in infants. J Exp Med 2008;205:1331-1342.
    • (2008) J Exp Med , vol.205 , pp. 1331-1342
    • Weller, S.1
  • 137
    • 45149097661 scopus 로고    scopus 로고
    • Sheepish B cells: evidence for antigen-independent antibody diversification in humans and mice
    • Tarlinton D. Sheepish B cells: evidence for antigen-independent antibody diversification in humans and mice. J Exp Med 2008;205:1251-1254.
    • (2008) J Exp Med , vol.205 , pp. 1251-1254
    • Tarlinton, D.1
  • 138
    • 84942930366 scopus 로고    scopus 로고
    • Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers
    • Budeus B, Schweigle de Reynoso S, Przekopowitz M, Hoffmann D, Seifert M, Kuppers R. Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers. Proc Natl Acad Sci USA 2015;112:E5281-E5289.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. E5281-E5289
    • Budeus, B.1    Schweigle de Reynoso, S.2    Przekopowitz, M.3    Hoffmann, D.4    Seifert, M.5    Kuppers, R.6
  • 139
    • 84883741301 scopus 로고    scopus 로고
    • Microbial colonization influences early B-lineage development in the gut lamina propria
    • Wesemann DR, et al. Microbial colonization influences early B-lineage development in the gut lamina propria. Nature 2013;501:112-115.
    • (2013) Nature , vol.501 , pp. 112-115
    • Wesemann, D.R.1
  • 140
    • 84864331772 scopus 로고    scopus 로고
    • Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal, and affinity-matured gut IgA responses
    • Bergqvist P, et al. Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal, and affinity-matured gut IgA responses. Mucosal Immunol 2013;6:122-135.
    • (2013) Mucosal Immunol , vol.6 , pp. 122-135
    • Bergqvist, P.1
  • 141
    • 84921515658 scopus 로고    scopus 로고
    • Loss of signalling via Galpha13 in germinal centre B-cell-derived lymphoma
    • Muppidi JR, et al. Loss of signalling via Galpha13 in germinal centre B-cell-derived lymphoma. Nature 2014;516:254-258.
    • (2014) Nature , vol.516 , pp. 254-258
    • Muppidi, J.R.1
  • 142
    • 84859717525 scopus 로고    scopus 로고
    • Germinal center selection and the development of memory B and plasma cells
    • Shlomchik MJ, Weisel F. Germinal center selection and the development of memory B and plasma cells. Immunol Rev 2012;247:52-63.
    • (2012) Immunol Rev , vol.247 , pp. 52-63
    • Shlomchik, M.J.1    Weisel, F.2
  • 143
    • 84856872027 scopus 로고    scopus 로고
    • Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine
    • Lindner C, et al. Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine. J Exp Med 2012;209:365-377.
    • (2012) J Exp Med , vol.209 , pp. 365-377
    • Lindner, C.1
  • 144
    • 48849115839 scopus 로고    scopus 로고
    • Differentiation and homing of IgA-secreting cells
    • Mora JR, von Andrian UH. Differentiation and homing of IgA-secreting cells. Mucosal Immunol 2008;1:96-109.
    • (2008) Mucosal Immunol , vol.1 , pp. 96-109
    • Mora, J.R.1    von Andrian, U.H.2
  • 146
    • 56149099480 scopus 로고    scopus 로고
    • Cutting edge: instructive role of peripheral tissue cells in the imprinting of T cell homing receptor patterns
    • Edele F, et al. Cutting edge: instructive role of peripheral tissue cells in the imprinting of T cell homing receptor patterns. J Immunol 2008;181:3745-3749.
    • (2008) J Immunol , vol.181 , pp. 3745-3749
    • Edele, F.1
  • 147
    • 58149145656 scopus 로고    scopus 로고
    • Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo
    • Hammerschmidt SI, et al. Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo. J Exp Med 2008;205:2483-2490.
    • (2008) J Exp Med , vol.205 , pp. 2483-2490
    • Hammerschmidt, S.I.1
  • 148
    • 75149189349 scopus 로고    scopus 로고
    • Lymph node stromal cells support dendritic cell-induced gut-homing of T cells
    • Molenaar R, et al. Lymph node stromal cells support dendritic cell-induced gut-homing of T cells. J Immunol 2009;183:6395-6402.
    • (2009) J Immunol , vol.183 , pp. 6395-6402
    • Molenaar, R.1
  • 149
    • 84880998384 scopus 로고    scopus 로고
    • Retinoic acid, acting as a highly specific IgA isotype switch factor, cooperates with TGF-beta1 to enhance the overall IgA response
    • Seo GY, et al. Retinoic acid, acting as a highly specific IgA isotype switch factor, cooperates with TGF-beta1 to enhance the overall IgA response. J Leukoc Biol 2013;94:325-335.
    • (2013) J Leukoc Biol , vol.94 , pp. 325-335
    • Seo, G.Y.1
  • 150
    • 33751530065 scopus 로고    scopus 로고
    • Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism
    • Kabashima K, et al. Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism. J Exp Med 2006;203:2683-2690.
    • (2006) J Exp Med , vol.203 , pp. 2683-2690
    • Kabashima, K.1
  • 151
    • 45949087769 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses
    • Gohda M, et al. Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses. J Immunol 2008;180:5335-5343.
    • (2008) J Immunol , vol.180 , pp. 5335-5343
    • Gohda, M.1
  • 152
    • 81055145340 scopus 로고    scopus 로고
    • Critical roles of chemokine receptor CCR10 in regulating memory IgA responses in intestines
    • Hu S, Yang K, Yang J, Li M, Xiong N. Critical roles of chemokine receptor CCR10 in regulating memory IgA responses in intestines. Proc Natl Acad Sci USA 2011;108:E1035-E1044.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. E1035-E1044
    • Hu, S.1    Yang, K.2    Yang, J.3    Li, M.4    Xiong, N.5
  • 153
    • 0037382166 scopus 로고    scopus 로고
    • CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells
    • Kunkel EJ, et al. CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. J Clin Invest 2003;111:1001-1010.
    • (2003) J Clin Invest , vol.111 , pp. 1001-1010
    • Kunkel, E.J.1
  • 154
    • 84908132881 scopus 로고    scopus 로고
    • Generation of colonic IgA-secreting cells in the caecal patch
    • Masahata K, et al. Generation of colonic IgA-secreting cells in the caecal patch. Nat Commun 2014;5:3704.
    • (2014) Nat Commun , vol.5 , pp. 3704
    • Masahata, K.1
  • 155
    • 84898681828 scopus 로고    scopus 로고
    • Eosinophils promote generation and maintenance of immunoglobulin-A-expressing plasma cells and contribute to gut immune homeostasis
    • Chu VT, et al. Eosinophils promote generation and maintenance of immunoglobulin-A-expressing plasma cells and contribute to gut immune homeostasis. Immunity 2014;40:582-593.
    • (2014) Immunity , vol.40 , pp. 582-593
    • Chu, V.T.1
  • 156
    • 84928896887 scopus 로고    scopus 로고
    • IL-1beta in eosinophil-mediated small intestinal homeostasis and IgA production
    • Jung Y, et al. IL-1beta in eosinophil-mediated small intestinal homeostasis and IgA production. Mucosal Immunol 2015;8:930-942.
    • (2015) Mucosal Immunol , vol.8 , pp. 930-942
    • Jung, Y.1
  • 157
    • 0029934454 scopus 로고    scopus 로고
    • IL-6-deficient mice exhibit normal mucosal IgA responses to local immunizations and Helicobacter felis infection
    • Bromander AK, Ekman L, Kopf M, Nedrud JG, Lycke NY. IL-6-deficient mice exhibit normal mucosal IgA responses to local immunizations and Helicobacter felis infection. J Immunol 1996;156:4290-4297.
    • (1996) J Immunol , vol.156 , pp. 4290-4297
    • Bromander, A.K.1    Ekman, L.2    Kopf, M.3    Nedrud, J.G.4    Lycke, N.Y.5
  • 158
    • 84864296905 scopus 로고    scopus 로고
    • Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation
    • Joo H, et al. Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation. J Exp Med 2012;209:1335-1348.
    • (2012) J Exp Med , vol.209 , pp. 1335-1348
    • Joo, H.1
  • 159
    • 84953305702 scopus 로고    scopus 로고
    • Long-lived plasma cells are generated in mucosal immune responses and contribute to the bone marrow plasma cell pool in mice
    • Lemke A, Kraft M, Roth K, Riedel R, Lammerding D, Hauser AE. Long-lived plasma cells are generated in mucosal immune responses and contribute to the bone marrow plasma cell pool in mice. Mucosal Immunol 2015;doi: 10.1038/mi.2015.38.
    • (2015) Mucosal Immunol
    • Lemke, A.1    Kraft, M.2    Roth, K.3    Riedel, R.4    Lammerding, D.5    Hauser, A.E.6
  • 160
    • 0015829619 scopus 로고
    • The life span of IgA plasma cells from the mouse intestine
    • Mattioli CA, Tomasi TB Jr. The life span of IgA plasma cells from the mouse intestine. J Exp Med 1973;138:452-460.
    • (1973) J Exp Med , vol.138 , pp. 452-460
    • Mattioli, C.A.1    Tomasi, T.B.2
  • 162
    • 84869839252 scopus 로고    scopus 로고
    • IgA response in preterm neonates shows little evidence of antigen-driven selection
    • Rogosch T, et al. IgA response in preterm neonates shows little evidence of antigen-driven selection. J Immunol 2012;189:5449-5456.
    • (2012) J Immunol , vol.189 , pp. 5449-5456
    • Rogosch, T.1
  • 163
    • 77954051526 scopus 로고    scopus 로고
    • Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses
    • Hapfelmeier S, et al. Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses. Science 2010;328:1705-1709.
    • (2010) Science , vol.328 , pp. 1705-1709
    • Hapfelmeier, S.1
  • 164
    • 70449276163 scopus 로고
    • Plasma cell proliferation following whole body irradiation
    • Nossal GJ. Plasma cell proliferation following whole body irradiation. Aust J Exp Biol Med Sci 1959;37:499-504.
    • (1959) Aust J Exp Biol Med Sci , vol.37 , pp. 499-504
    • Nossal, G.J.1
  • 165
    • 0033561766 scopus 로고    scopus 로고
    • Induction of mucosal immunity by inactivated poliovirus vaccine is dependent on previous mucosal contact with live virus
    • Herremans TM, Reimerink JH, Buisman AM, Kimman TG, Koopmans MP. Induction of mucosal immunity by inactivated poliovirus vaccine is dependent on previous mucosal contact with live virus. J Immunol 1999;162:5011-5018.
    • (1999) J Immunol , vol.162 , pp. 5011-5018
    • Herremans, T.M.1    Reimerink, J.H.2    Buisman, A.M.3    Kimman, T.G.4    Koopmans, M.P.5
  • 166
    • 0018929057 scopus 로고
    • Intestinal immune response to cholera toxin: dependence on route and dosage of antigen for priming and boosting
    • Svennerholm AM, Lange S, Holmgren J. Intestinal immune response to cholera toxin: dependence on route and dosage of antigen for priming and boosting. Infect Immun 1980;30:337-341.
    • (1980) Infect Immun , vol.30 , pp. 337-341
    • Svennerholm, A.M.1    Lange, S.2    Holmgren, J.3
  • 167
    • 0022512531 scopus 로고
    • Intestinal mucosal memory and presence of memory cells in lamina propria and Peyer's patches in mice 2 years after oral immunization with cholera toxin
    • Lycke N, Holmgren J. Intestinal mucosal memory and presence of memory cells in lamina propria and Peyer's patches in mice 2 years after oral immunization with cholera toxin. Scand J Immunol 1986;23:611-616.
    • (1986) Scand J Immunol , vol.23 , pp. 611-616
    • Lycke, N.1    Holmgren, J.2
  • 168
    • 0023635901 scopus 로고
    • Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours of an oral challenge immunization
    • Lycke N, Holmgren J. Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours of an oral challenge immunization. Scand J Immunol 1987;25:407-412.
    • (1987) Scand J Immunol , vol.25 , pp. 407-412
    • Lycke, N.1    Holmgren, J.2
  • 169
    • 0024513124 scopus 로고
    • Adoptive transfer of gut mucosal antitoxin memory by isolated B cells 1 year after oral immunization with cholera toxin
    • Lycke N, Holmgren J. Adoptive transfer of gut mucosal antitoxin memory by isolated B cells 1 year after oral immunization with cholera toxin. Infect Immun 1989;57:1137-1141.
    • (1989) Infect Immun , vol.57 , pp. 1137-1141
    • Lycke, N.1    Holmgren, J.2
  • 171
    • 84907300008 scopus 로고    scopus 로고
    • Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease
    • Palm NW, et al. Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease. Cell 2014;158:1000-1010.
    • (2014) Cell , vol.158 , pp. 1000-1010
    • Palm, N.W.1
  • 172
    • 0034108060 scopus 로고    scopus 로고
    • Selective IgA deficiency (SIgAD) and common variable immunodeficiency (CVID)
    • Hammarstrom L, Vorechovsky I, Webster D. Selective IgA deficiency (SIgAD) and common variable immunodeficiency (CVID). Clin Exp Immunol 2000;120:225-231.
    • (2000) Clin Exp Immunol , vol.120 , pp. 225-231
    • Hammarstrom, L.1    Vorechovsky, I.2    Webster, D.3
  • 173
    • 84908667647 scopus 로고    scopus 로고
    • Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
    • Kiryluk K, et al. Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens. Nat Genet 2014;46:1187-1196.
    • (2014) Nat Genet , vol.46 , pp. 1187-1196
    • Kiryluk, K.1


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