메뉴 건너뛰기




Volumn 16, Issue 3, 2015, Pages 296-305

Class-switched memory B cells remodel BCRs within secondary germinal centers

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD83 ANTIGEN; DNA DIRECTED DNA POLYMERASE; IMMUNOGLOBULIN; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN;

EID: 84922619699     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3095     Document Type: Article
Times cited : (185)

References (50)
  • 1
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH
    • Crotty S. Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 29, 621-663 (2011
    • (2011) Annu. Rev. Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 6
    • 33846635838 scopus 로고    scopus 로고
    • Imaging of germinal center selection events during affinity maturation
    • Allen C.D., Okada T., Tang H.L. & Cyster J.G. Imaging of germinal center selection events during affinity maturation. Science 315, 528-531 (2007
    • (2007) Science , vol.315 , pp. 528-531
    • Allen, C.D.1    Okada, T.2    Tang, H.L.3    Cyster, J.G.4
  • 7
    • 34248585765 scopus 로고    scopus 로고
    • Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns
    • Hauser A.E., et al. Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns. Immunity 26, 655-667 (2007
    • (2007) Immunity , vol.26 , pp. 655-667
    • Hauser, A.E.1
  • 8
    • 33847206141 scopus 로고    scopus 로고
    • In vivo imaging of germinal centres reveals a dynamic open structure
    • Schwickert T.A., et al. In vivo imaging of germinal centres reveals a dynamic open structure. Nature 446, 83-87 (2007
    • (2007) Nature , vol.446 , pp. 83-87
    • Schwickert, T.A.1
  • 9
    • 78149477766 scopus 로고    scopus 로고
    • Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter
    • Victora G.D., et al. Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell 143, 592-605 (2010
    • (2010) Cell , vol.143 , pp. 592-605
    • Victora, G.D.1
  • 10
    • 84881252552 scopus 로고    scopus 로고
    • T follicular helper cell dynamics in germinal centers
    • Shulman Z., et al. T follicular helper cell dynamics in germinal centers. Science 341, 673-677 (2013
    • (2013) Science , vol.341 , pp. 673-677
    • Shulman, Z.1
  • 11
    • 84890233027 scopus 로고    scopus 로고
    • Germinal center centroblasts transition to a centrocyte phenotype according to a timed program and depend on the dark zone for effective selection
    • Bannard O., et al. Germinal center centroblasts transition to a centrocyte phenotype according to a timed program and depend on the dark zone for effective selection. Immunity 39, 912-924 (2013
    • (2013) Immunity , vol.39 , pp. 912-924
    • Bannard, O.1
  • 12
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • Rajewsky K. Clonal selection and learning in the antibody system. Nature 381, 751-758 (1996
    • (1996) Nature , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 13
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu M., et al. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102, 553-563 (2000
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1
  • 14
    • 84907272327 scopus 로고    scopus 로고
    • Dynamic signaling by T follicular helper cells during germinal center B cell selection
    • Shulman Z., et al. Dynamic signaling by T follicular helper cells during germinal center B cell selection. Science 345, 1058-1062 (2014
    • (2014) Science , vol.345 , pp. 1058-1062
    • Shulman, Z.1
  • 15
    • 84901644301 scopus 로고    scopus 로고
    • Clonal selection in the germinal centre by regulated proliferation and hypermutation
    • Gitlin A.D., Shulman Z. & Nussenzweig M.C. Clonal selection in the germinal centre by regulated proliferation and hypermutation. Nature 509, 637-640 (2014
    • (2014) Nature , vol.509 , pp. 637-640
    • Gitlin, A.D.1    Shulman, Z.2    Nussenzweig, M.C.3
  • 16
    • 0026331458 scopus 로고
    • Maturation of the immune response in germinal centers
    • Berek C., Berger A. & Apel M. Maturation of the immune response in germinal centers. Cell 67, 1121-1129 (1991
    • (1991) Cell , vol.67 , pp. 1121-1129
    • Berek, C.1    Berger, A.2    Apel, M.3
  • 17
    • 0026060620 scopus 로고
    • Intraclonal generation of antibody mutants in germinal centres
    • Jacob J., Kelsoe G., Rajewsky K. & Weiss U. Intraclonal generation of antibody mutants in germinal centres. Nature 354, 389-392 (1991
    • (1991) Nature , vol.354 , pp. 389-392
    • Jacob, J.1    Kelsoe, G.2    Rajewsky, K.3    Weiss, U.4
  • 18
    • 0023161403 scopus 로고
    • Timing genetic requirements and functional consequences of somatic hypermutation during B-cell development
    • Allen D., et al. Timing genetic requirements and functional consequences of somatic hypermutation during B-cell development. Immunol. Rev. 96, 5-22 (1987
    • (1987) Immunol. Rev , vol.96 , pp. 5-22
    • Allen, D.1
  • 19
    • 0023161406 scopus 로고
    • Mutation drift and repertoire shift in the maturation of the immune response
    • Berek C. & Milstein C. Mutation drift and repertoire shift in the maturation of the immune response. Immunol. Rev. 96, 23-41 (1987
    • (1987) Immunol. Rev , vol.96 , pp. 23-41
    • Berek, C.1    Milstein, C.2
  • 20
    • 0023652377 scopus 로고
    • Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses
    • Siekevitz M., Kocks C., Rajewsky K. & Dildrop R. Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses. Cell 48, 757-770 (1987
    • (1987) Cell , vol.48 , pp. 757-770
    • Siekevitz, M.1    Kocks, C.2    Rajewsky, K.3    Dildrop, R.4
  • 21
    • 69549120041 scopus 로고    scopus 로고
    • Distinction of the memory B cell response to cognate antigen versus bystander inflammatory signals
    • Benson M.J., et al. Distinction of the memory B cell response to cognate antigen versus bystander inflammatory signals. J. Exp. Med. 206, 2013-2025 (2009
    • (2009) J. Exp. Med , vol.206 , pp. 2013-2025
    • Benson, M.J.1
  • 22
    • 79952282195 scopus 로고    scopus 로고
    • Different B cell populations mediate early and late memory during an endogenous immune response
    • Pape K.A., Taylor J.J., Maul R.W., Gearhart P.J. & Jenkins M.K. Different B cell populations mediate early and late memory during an endogenous immune response. Science 331, 1203-1207 (2011
    • (2011) Science , vol.331 , pp. 1203-1207
    • Pape, K.A.1    Taylor, J.J.2    Maul, R.W.3    Gearhart, P.J.4    Jenkins, M.K.5
  • 23
    • 70449722777 scopus 로고    scopus 로고
    • Multiple layers of B cell memory with different effector functions
    • Dogan I., et al. Multiple layers of B cell memory with different effector functions. Nat. Immunol. 10, 1292-1299 (2009
    • (2009) Nat. Immunol , vol.10 , pp. 1292-1299
    • Dogan, I.1
  • 24
    • 84902170182 scopus 로고    scopus 로고
    • Viral particles drive rapid differentiation of memory B cells into secondary plasma cells producing increased levels of antibodies
    • Zabel F., et al. Viral particles drive rapid differentiation of memory B cells into secondary plasma cells producing increased levels of antibodies. J. Immunol. 192, 5499-5508 (2014
    • (2014) J. Immunol , vol.192 , pp. 5499-5508
    • Zabel, F.1
  • 25
    • 84880752273 scopus 로고    scopus 로고
    • Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation
    • Kometani K., et al. Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation. Immunity 39, 136-147 (2013
    • (2013) Immunity , vol.39 , pp. 136-147
    • Kometani, K.1
  • 26
    • 84875551472 scopus 로고    scopus 로고
    • Broadly neutralizing antiviral antibodies
    • Corti D. & Lanzavecchia A. Broadly neutralizing antiviral antibodies. Annu. Rev. Immunol. 31, 705-742 (2013
    • (2013) Annu. Rev. Immunol , vol.31 , pp. 705-742
    • Corti, D.1    Lanzavecchia, A.2
  • 27
    • 84905369598 scopus 로고    scopus 로고
    • Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies
    • Gao F., et al. Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies. Cell 158, 481-491 (2014
    • (2014) Cell , vol.158 , pp. 481-491
    • Gao, F.1
  • 28
    • 84874092680 scopus 로고    scopus 로고
    • Lineage structure of the human antibody repertoire in response to influenza vaccination
    • 171ra119
    • Jiang N., et al. Lineage structure of the human antibody repertoire in response to influenza vaccination. Sci. Transl. Med. 5, 171ra119 (2013
    • (2013) Sci. Transl. Med , vol.5
    • Jiang, N.1
  • 29
    • 84875759341 scopus 로고    scopus 로고
    • Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization
    • Klein F., et al. Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Cell 153, 126-138 (2013
    • (2013) Cell , vol.153 , pp. 126-138
    • Klein, F.1
  • 30
    • 84876797103 scopus 로고    scopus 로고
    • Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
    • Liao H.X., et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature 496, 469-476 (2013
    • (2013) Nature , vol.496 , pp. 469-476
    • Liao, H.X.1
  • 32
    • 84894173514 scopus 로고    scopus 로고
    • Structural insights on the role of antibodies in HIV-1 vaccine and therapy
    • West A.P. Jr., et al. Structural insights on the role of antibodies in HIV-1 vaccine and therapy. Cell 156, 633-648 (2014
    • (2014) Cell , vol.156 , pp. 633-648
    • West, A.P.1
  • 33
    • 44449118948 scopus 로고    scopus 로고
    • Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
    • Wrammert J., et al. Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature 453, 667-671 (2008
    • (2008) Nature , vol.453 , pp. 667-671
    • Wrammert, J.1
  • 34
    • 84888799995 scopus 로고    scopus 로고
    • Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus
    • Kaji T., et al. Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus. Int. Immunol. 25, 683-695 (2013
    • (2013) Int. Immunol , vol.25 , pp. 683-695
    • Kaji, T.1
  • 35
    • 84903646784 scopus 로고    scopus 로고
    • CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype
    • Zuccarino-Catania G.V., et al. CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype. Nat. Immunol. 15, 631-637 (2014
    • (2014) Nat. Immunol , vol.15 , pp. 631-637
    • Zuccarino-Catania, G.V.1
  • 36
    • 0034599971 scopus 로고    scopus 로고
    • Antigen-specific B cell memory: Expression and replenishment of a novel b220(-) memory b cell compartment
    • McHeyzer-Williams L.J., Cool M. & McHeyzer-Williams M.G. Antigen-specific B cell memory: expression and replenishment of a novel b220(-) memory b cell compartment. J. Exp. Med. 191, 1149-1166 (2000
    • (2000) J. Exp. Med , vol.191 , pp. 1149-1166
    • McHeyzer-Williams, L.J.1    Cool, M.2    McHeyzer-Williams, M.G.3
  • 37
    • 0025783070 scopus 로고
    • Molecular characterization of single memory B cells
    • McHeyzer-Williams M.G., Nossal G.J. & Lalor P.A. Molecular characterization of single memory B cells. Nature 350, 502-505 (1991
    • (1991) Nature , vol.350 , pp. 502-505
    • McHeyzer-Williams, M.G.1    Nossal, G.J.2    Lalor, P.A.3
  • 38
    • 0142219442 scopus 로고    scopus 로고
    • Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells
    • Shapiro-Shelef M., et al. Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity 19, 607-620 (2003
    • (2003) Immunity , vol.19 , pp. 607-620
    • Shapiro-Shelef, M.1
  • 39
    • 84868007353 scopus 로고    scopus 로고
    • Dendroscope 3: An interactive tool for rooted phylogenetic trees and networks
    • Huson D.H. & Scornavacca C. Dendroscope 3: an interactive tool for rooted phylogenetic trees and networks. Syst. Biol. 61, 1061-1067 (2012
    • (2012) Syst. Biol , vol.61 , pp. 1061-1067
    • Huson, D.H.1    Scornavacca, C.2
  • 40
    • 84880280631 scopus 로고    scopus 로고
    • Visne enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia
    • Amir el, A.D., et al. viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia. Nat. Biotechnol. 31, 545-552 (2013
    • (2013) Nat. Biotechnol , vol.31 , pp. 545-552
    • Amir El, A.D.1
  • 41
    • 33846404877 scopus 로고    scopus 로고
    • DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse
    • Delbos F., Aoufouchi S., Faili A., Weill J.C. & Reynaud C.A. DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse. J. Exp. Med. 204, 17-23 (2007
    • (2007) J. Exp. Med , vol.204 , pp. 17-23
    • Delbos, F.1    Aoufouchi, S.2    Faili, A.3    Weill, J.C.4    Reynaud, C.A.5
  • 42
    • 78651482270 scopus 로고    scopus 로고
    • Cd83 increases mhc ii and cd86 on dendritic cells by opposing il-10-driven march1-mediated ubiquitination and degradation
    • Tze L.E., et al. CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. J. Exp. Med. 208, 149-165 (2011
    • (2011) J. Exp. Med , vol.208 , pp. 149-165
    • Tze, L.E.1
  • 43
    • 79952173864 scopus 로고    scopus 로고
    • Programming the magnitude and persistence of antibody responses with innate immunity
    • Kasturi S.P., et al. Programming the magnitude and persistence of antibody responses with innate immunity. Nature 470, 543-547 (2011
    • (2011) Nature , vol.470 , pp. 543-547
    • Kasturi, S.P.1
  • 45
    • 84870276111 scopus 로고    scopus 로고
    • Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory
    • Kaji T., et al. Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory. J. Exp. Med. 209, 2079-2097 (2012
    • (2012) J. Exp. Med , vol.209 , pp. 2079-2097
    • Kaji, T.1
  • 46
    • 84860363209 scopus 로고    scopus 로고
    • A germinal center-independent pathway generates unswitched memory B cells early in the primary response
    • Taylor J.J., Pape K.A. & Jenkins M.K. A germinal center-independent pathway generates unswitched memory B cells early in the primary response. J. Exp. Med. 209, 597-606 (2012
    • (2012) J. Exp. Med , vol.209 , pp. 597-606
    • Taylor, J.J.1    Pape, K.A.2    Jenkins, M.K.3
  • 47
    • 0035940511 scopus 로고    scopus 로고
    • A hallmark of active class switch recombination: Transcripts directed by i promoters on looped-out circular DNAs
    • Kinoshita K., Harigai M., Fagarasan S., Muramatsu M. & Honjo T. A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs. Proc. Natl. Acad. Sci. USA 98, 12620-12623 (2001
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12620-12623
    • Kinoshita, K.1    Harigai, M.2    Fagarasan, S.3    Muramatsu, M.4    Honjo, T.5
  • 48
    • 84867730760 scopus 로고    scopus 로고
    • The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers
    • Calado D.P., et al. The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers. Nat. Immunol. 13, 1092-1100 (2012
    • (2012) Nat. Immunol , vol.13 , pp. 1092-1100
    • Calado, D.P.1
  • 49
    • 84867709361 scopus 로고    scopus 로고
    • The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry
    • Dominguez-Sola D., et al. The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry. Nat. Immunol. 13, 1083-1091 (2012
    • (2012) Nat. Immunol , vol.13 , pp. 1083-1091
    • Dominguez-Sola, D.1
  • 50
    • 77955460838 scopus 로고    scopus 로고
    • Preferential localization of IgG memory B cells adjacent to contracted germinal centers
    • Aiba Y., et al. Preferential localization of IgG memory B cells adjacent to contracted germinal centers. Proc. Natl. Acad. Sci. USA 107, 12192-12197 (2010
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 12192-12197
    • Aiba, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.