Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota

Nature Immunology

Volumn 16, Issue 8, 2015, Pages 880-888

  Lindner, Cornelia ^a   Thomsen, Irene ^a   Wahl, Benjamin ^a   Ugur, Milas ^a   Sethi, Maya K ^a   Friedrichsen, Michaela ^a   Smoczek, Anna ^a   Ott, Stephan ^b   Baumann, Ulrich ^a   Suerbaum, Sebastian ^a   Schreiber, Stefan ^b   Bleich, André ^a   Gaboriau Routhiau, Valérie ^c   Cerf Bensussan, Nadine ^c   Hazanov, Helena ^d   Mehr, Ramit ^d   Boysen, Preben ^e   Rosenstiel, Philip ^b   Pabst, Oliver ^a,f  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c IMAGINE INSTITUTE   (France)

^d BAR ILAN UNIVERSITY   (Israel)

^e NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^f RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SECRETORY IMMUNOGLOBULIN; ANTIBODY; ANTIINFECTIVE AGENT; IMMUNOGLOBULIN A; RNA 16S;

ADAPTATION; ADULT; ANIMAL CELL; ANTIBIOTIC THERAPY; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; INTESTINE EPITHELIUM; INTESTINE FLORA; MEMORY CELL; MOUSE; MUTATION RATE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; SOMATIC MUTATION; SYMBIOSIS; ANIMAL; B LYMPHOCYTE; C57BL MOUSE; DRUG EFFECTS; FEMALE; GASTROINTESTINAL TRACT; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MICROFLORA; MUTATION; PHYSIOLOGY; TRANSGENIC MOUSE; UDDER; YOUNG ADULT;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES; B-LYMPHOCYTES; FEMALE; GASTROINTESTINAL TRACT; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A, SECRETORY; IMMUNOLOGIC MEMORY; MAMMARY GLANDS, ANIMAL; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROBIOTA; MUTATION; PLASMA CELLS; RNA, RIBOSOMAL, 16S; SYMBIOSIS; YOUNG ADULT;

EID: 84937814800     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3213     Document Type: Article

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