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Volumn 184, Issue 7, 2010, Pages 3545-3553

T cell-independent IgA class switch recombination is restricted to the GALT and occurs prior to manifest germinal center formation

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; COMPLEMENTARY DNA; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS; MESSENGER RNA; MOLECULAR MARKER;

EID: 77951639699     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901895     Document Type: Article
Times cited : (110)

References (49)
  • 1
    • 33746882656 scopus 로고    scopus 로고
    • IgA B cell development
    • 3rd Ed. J. Mestecky, M. E. Lamm, W. Strober, J.Bienenstock, J. R. McGhee, and L. Mayer, eds. Academic Press, Boston
    • Strober, W., S. Fagarasan, and N. Lycke. 2005. IgA B cell development. In Mucosal immunology, 3rd Ed. J. Mestecky, M. E. Lamm, W. Strober, J.Bienenstock, J. R. McGhee, and L. Mayer, eds. Academic Press, Boston. p. 583-616.
    • (2005) Mucosal Immunology , pp. 583-616
    • Strober, W.1    Fagarasan, S.2    Lycke, N.3
  • 2
    • 42649123314 scopus 로고    scopus 로고
    • Mechanism and regulation of class switch recombination
    • Stavnezer, J., J. E. Guikema, and C. E. Schrader. 2008. Mechanism and regulation of class switch recombination. Annu. Rev. Immunol. 26: 261-292.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 261-292
    • Stavnezer, J.1    Guikema, J.E.2    Schrader, C.E.3
  • 3
    • 44349195660 scopus 로고    scopus 로고
    • The regulation of IgA class switching
    • Cerutti, A. 2008. The regulation of IgA class switching. Nat. Rev. Immunol. 8: 421-434.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 421-434
    • Cerutti, A.1
  • 4
    • 44649193919 scopus 로고    scopus 로고
    • The biology of intestinal immunoglobulin a responses
    • Cerutti, A., and M. Rescigno. 2008. The biology of intestinal immunoglobulin A responses. Immunity 28: 740-750.
    • (2008) Immunity , vol.28 , pp. 740-750
    • Cerutti, A.1    Rescigno, M.2
  • 5
    • 65749095462 scopus 로고    scopus 로고
    • Generation of Immunoglobulin diversity in human gut-associated lymphoid tissue
    • Spencer, J., F. Barone, and D. Dunn-Walters. 2009. Generation of Immunoglobulin diversity in human gut-associated lymphoid tissue. Semin. Immunol. 21: 139-146.
    • (2009) Semin. Immunol. , vol.21 , pp. 139-146
    • Spencer, J.1    Barone, F.2    Dunn-Walters, D.3
  • 6
    • 0034705397 scopus 로고    scopus 로고
    • A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria
    • Macpherson, A. J., D. Gatto, E. Sainsbury, G. R. Harriman, H. Hengartner, and R. M. Zinkernagel. 2000. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 288: 2222-2226.
    • (2000) Science , vol.288 , pp. 2222-2226
    • Macpherson, A.J.1    Gatto, D.2    Sainsbury, E.3    Harriman, G.R.4    Hengartner, H.5    Zinkernagel, R.M.6
  • 8
    • 0037223217 scopus 로고    scopus 로고
    • Strong differential regulation of serum and mucosal IgA responses as revealed in CD28-deficient mice using cholera toxin adjuvant
    • Gärdby, E., J. Wrammert, K. Schön, L. Ekman, T. Leanderson, and N. Lycke. 2003. Strong differential regulation of serum and mucosal IgA responses as revealed in CD28-deficient mice using cholera toxin adjuvant. J. Immunol. 170: 55-63. (Pubitemid 36026123)
    • (2003) Journal of Immunology , vol.170 , Issue.1 , pp. 55-63
    • Gardby, E.1    Wrammert, J.2    Schon, K.3    Ekman, L.4    Leanderson, T.5    Lycke, N.6
  • 11
    • 34250205694 scopus 로고    scopus 로고
    • Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelialcell secretion of the cytokine APRIL
    • He, B., W. Xu, P. A. Santini, A. D. Polydorides, A. Chiu, J. Estrella, M. Shan, A. Chadburn, V. Villanacci, A. Plebani, et al. 2007. Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelialcell secretion of the cytokine APRIL. Immunity 26: 812-826.
    • (2007) Immunity , vol.26 , pp. 812-826
    • He, B.1    Xu, W.2    Santini, P.A.3    Polydorides, A.D.4    Chiu, A.5    Estrella, J.6    Shan, M.7    Chadburn, A.8    Villanacci, V.9    Plebani, A.10
  • 12
    • 33749180625 scopus 로고    scopus 로고
    • Intestinal IgA synthesis: A primitive form of adaptive immunity that regulates microbial communities in the gut
    • Fagarasan, S. 2006. Intestinal IgA synthesis: a primitive form of adaptive immunity that regulates microbial communities in the gut. Curr. Top. Microbiol. Immunol. 308: 137-153.
    • (2006) Curr. Top. Microbiol. Immunol. , vol.308 , pp. 137-153
    • Fagarasan, S.1
  • 13
    • 0015177024 scopus 로고
    • Immunoglobulins in intact, immunized, and contaminated axenic mice: Study of serum IgA
    • Benveniste, J., G. Lespinats, C. Adam, and J. C. Salomon. 1971. Immunoglobulins in intact, immunized, and contaminated axenic mice: study of serum IgA. J. Immunol. 107: 1647-1655.
    • (1971) J. Immunol. , vol.107 , pp. 1647-1655
    • Benveniste, J.1    Lespinats, G.2    Adam, C.3    Salomon, J.C.4
  • 14
    • 0015173745 scopus 로고
    • Serum and secretory IgA in axenic and holoxenic mice
    • Benveniste, J., G. Lespinats, and J. Salomon. 1971. Serum and secretory IgA in axenic and holoxenic mice. J. Immunol. 107: 1656-1662.
    • (1971) J. Immunol. , vol.107 , pp. 1656-1662
    • Benveniste, J.1    Lespinats, G.2    Salomon, J.3
  • 15
    • 0034802944 scopus 로고    scopus 로고
    • IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms
    • Macpherson, A. J., L. Hunziker, K. McCoy, and A. Lamarre. 2001. IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms. Microbes Infect. 3: 1021-1035.
    • (2001) Microbes Infect. , vol.3 , pp. 1021-1035
    • Macpherson, A.J.1    Hunziker, L.2    McCoy, K.3    Lamarre, A.4
  • 16
    • 35848931007 scopus 로고    scopus 로고
    • IgA response to symbiotic bacteria as a mediator of gut homeostasis
    • Peterson, D. A., N. P. McNulty, J. L. Guruge, and J. I. Gordon. 2007. IgA response to symbiotic bacteria as a mediator of gut homeostasis. Cell Host Microbe 2: 328-339.
    • (2007) Cell Host Microbe , vol.2 , pp. 328-339
    • Peterson, D.A.1    McNulty, N.P.2    Guruge, J.L.3    Gordon, J.I.4
  • 17
    • 44349130296 scopus 로고    scopus 로고
    • Location, location, location: B-cell differentiation in the gut lamina propria
    • Cerutti, A. 2008. Location, location, location: B-cell differentiation in the gut lamina propria. Mucosal Immunol 1: 8-10.
    • (2008) Mucosal Immunol , vol.1 , pp. 8-10
    • Cerutti, A.1
  • 18
    • 0015097333 scopus 로고
    • Peyer's patches: An enriched source of precursors for IgA-producing immunocytes in the rabbit
    • Craig, S. W., and J. J. Cebra. 1971. Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit. J. Exp. Med. 134: 188-200.
    • (1971) J. Exp. Med. , vol.134 , pp. 188-200
    • Craig, S.W.1    Cebra, J.J.2
  • 19
    • 0018116086 scopus 로고
    • The origin and antigen-dependent distribution of IgA-containing cells in the intestine
    • Husband, A. J., and J. L. Gowans. 1978. The origin and antigen-dependent distribution of IgA-containing cells in the intestine. J. Exp. Med. 148: 1146-1160.
    • (1978) J. Exp. Med. , vol.148 , pp. 1146-1160
    • Husband, A.J.1    Gowans, J.L.2
  • 20
    • 0035846113 scopus 로고    scopus 로고
    • In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
    • Fagarasan, S., K. Kinoshita, M. Muramatsu, K. Ikuta, and T. Honjo. 2001. In situ class switching and differentiation to IgA-producing cells in the gut lamina propria. Nature 413: 639-643.
    • (2001) Nature , vol.413 , pp. 639-643
    • Fagarasan, S.1    Kinoshita, K.2    Muramatsu, M.3    Ikuta, K.4    Honjo, T.5
  • 22
    • 34548176272 scopus 로고    scopus 로고
    • Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells
    • DOI 10.1038/nature06033, PII NATURE06033
    • Tezuka, H., Y. Abe, M. Iwata, H. Takeuchi, H. Ishikawa, M. Matsushita, T. Shiohara, S. Akira, and T. Ohteki. 2007. Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells. Nature 448: 929-933. (Pubitemid 47312771)
    • (2007) Nature , vol.448 , Issue.7156 , pp. 929-933
    • Tezuka, H.1    Abe, Y.2    Iwata, M.3    Takeuchi, H.4    Ishikawa, H.5    Matsushita, M.6    Shiohara, T.7    Akira, S.8    Ohteki, T.9
  • 23
    • 59849123627 scopus 로고    scopus 로고
    • The surprising discovery that TGF beta specifically induces the IgA class switch
    • Stavnezer, J., and J. Kang. 2009. The surprising discovery that TGF beta specifically induces the IgA class switch. J. Immunol. 182: 5-7.
    • (2009) J. Immunol. , vol.182 , pp. 5-7
    • Stavnezer, J.1    Kang, J.2
  • 24
    • 1542513365 scopus 로고    scopus 로고
    • Textbook germinal centers?
    • Manser, T. 2004. Textbook germinal centers? J. Immunol. 172: 3369-3375.
    • (2004) J. Immunol. , vol.172 , pp. 3369-3375
    • Manser, T.1
  • 25
    • 0242495542 scopus 로고    scopus 로고
    • EBV-Encoded Latent Membrane Protein 1 Cooperates with BAFF/BLyS and APRIL to Induce T Cell-Independent Ig Heavy Chain Class Switching
    • He, B., N. Raab-Traub, P. Casali, and A. Cerutti. 2003. EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching. J. Immunol. 171: 5215-5224. (Pubitemid 37432806)
    • (2003) Journal of Immunology , vol.171 , Issue.10 , pp. 5215-5224
    • He, B.1    Raab-Traub, N.2    Casali, P.3    Cerutti, A.4
  • 27
  • 28
    • 35348904427 scopus 로고    scopus 로고
    • TACI, isotype switching, CVID and IgAD
    • Castigli, E., and R. S. Geha. 2007. TACI, isotype switching, CVID and IgAD. Immunol. Res. 38: 102-111.
    • (2007) Immunol. Res. , vol.38 , pp. 102-111
    • Castigli, E.1    Geha, R.S.2
  • 29
    • 33750484683 scopus 로고    scopus 로고
    • BAFF induces a hyper-IgA syndrome in the intestinal lamina propria concomitant with IgA deposition in the kidney independent of LIGHT
    • McCarthy, D. D., S. Chiu, Y. Gao, L. E. Summers-Deluca, and J. L. Gommerman. 2006. BAFF induces a hyper-IgA syndrome in the intestinal lamina propria concomitant with IgA deposition in the kidney independent of LIGHT. Cell. Immunol. 241: 85-94.
    • (2006) Cell. Immunol. , vol.241 , pp. 85-94
    • McCarthy, D.D.1    Chiu, S.2    Gao, Y.3    Summers-Deluca, L.E.4    Gommerman, J.L.5
  • 30
    • 33751577786 scopus 로고    scopus 로고
    • Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers
    • Bergqvist, P., E. Gärdby, A. Stensson, M. Bemark, and N. Y. Lycke. 2006. Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers. J. Immunol. 177: 7772-7783. (Pubitemid 44846293)
    • (2006) Journal of Immunology , vol.177 , Issue.11 , pp. 7772-7783
    • Bergqvist, P.1    Gardby, E.2    Stensson, A.3    Bemark, M.4    Lycke, N.Y.5
  • 31
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu, M., K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102: 553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 33
    • 24944541376 scopus 로고    scopus 로고
    • Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination
    • Rush, J. S., M. Liu, V. H. Odegard, S. Unniraman, and D. G. Schatz. 2005. Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination. Proc. Natl. Acad. Sci. U.S.A. 102: 13242-13247.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 13242-13247
    • Rush, J.S.1    Liu, M.2    Odegard, V.H.3    Unniraman, S.4    Schatz, D.G.5
  • 34
    • 0024468421 scopus 로고
    • Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity
    • Kroese, F. G., E. C. Butcher, A. M. Stall, P. A. Lalor, S. Adams, and L. A. Herzenberg. 1989. Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity. Int. Immunol. 1: 75-84.
    • (1989) Int. Immunol. , vol.1 , pp. 75-84
    • Kroese, F.G.1    Butcher, E.C.2    Stall, A.M.3    Lalor, P.A.4    Adams, S.5    Herzenberg, L.A.6
  • 35
    • 0030845386 scopus 로고    scopus 로고
    • Rapid methods for the analysis of immunoglobulin gene hypermutation: Application to transgenic and gene targeted mice
    • Jolly, C. J., N. Klix, and M. S. Neuberger. 1997. Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice. Nucleic Acids Res. 25: 1913-1919.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1913-1919
    • Jolly, C.J.1    Klix, N.2    Neuberger, M.S.3
  • 37
    • 20444498902 scopus 로고    scopus 로고
    • Human intestinal IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria
    • DOI 10.1053/j.gastro.2005.03.047, PII S0016508505005706
    • Boursier, L., J. N. Gordon, S. Thiagamoorthy, J. D. Edgeworth, and J. Spencer. 2005. Human intestinal IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria. Gastroenterology 128: 1879-1889. (Pubitemid 40824699)
    • (2005) Gastroenterology , vol.128 , Issue.7 , pp. 1879-1889
    • Boursier, L.1    Gordon, J.N.2    Thiagamoorthy, S.3    Edgeworth, J.D.4    Spencer, J.5
  • 38
    • 2442479518 scopus 로고    scopus 로고
    • IgA Class Switch Occurs in the Organized Nasopharynx- And Gut-Associated Lymphoid Tissue, but Not in the Diffuse Lamina Propria of Airways and Gut
    • Shikina, T., T. Hiroi, K. Iwatani, M. H. Jang, S. Fukuyama, M. Tamura, T. Kubo, H. Ishikawa, and H. Kiyono. 2004. IgA class switch occurs in the organized nasopharynx- and gut-associated lymphoid tissue, but not in the diffuse lamina propria of airways and gut. J. Immunol. 172: 6259-6264. (Pubitemid 38621232)
    • (2004) Journal of Immunology , vol.172 , Issue.10 , pp. 6259-6264
    • Shikina, T.1    Hiroi, T.2    Iwatani, K.3    Jang, M.H.4    Fukuyama, S.5    Tamura, M.6    Kubo, T.7    Ishikawa, H.8    Kiyono, H.9
  • 39
    • 0031045684 scopus 로고    scopus 로고
    • Sequence analysis of human IgVH genes indicates that ileal lamina propria plasma cells are derived from Peyer's patches
    • Dunn-Walters, D. K., P. G. Isaacson, and J. Spencer. 1997. Sequence analysis of human IgVH genes indicates that ileal lamina propria plasma cells are derived from Peyer's patches. Eur. J. Immunol. 27: 463-467.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 463-467
    • Dunn-Walters, D.K.1    Isaacson, P.G.2    Spencer, J.3
  • 41
    • 33645068450 scopus 로고    scopus 로고
    • Mesenteric lymph nodes at the center of immune anatomy
    • Macpherson, A. J., and K. Smith. 2006. Mesenteric lymph nodes at the center of immune anatomy. J. Exp. Med. 203: 497-500.
    • (2006) J. Exp. Med. , vol.203 , pp. 497-500
    • Macpherson, A.J.1    Smith, K.2
  • 42
    • 34147219234 scopus 로고    scopus 로고
    • Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation
    • Naito, Y., H. Takematsu, S. Koyama, S. Miyake, H. Yamamoto, R. Fujinawa, M. Sugai, Y. Okuno, G. Tsujimoto, T. Yamaji, et al. 2007. Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation. Mol. Cell. Biol. 27: 3008-3022.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 3008-3022
    • Naito, Y.1    Takematsu, H.2    Koyama, S.3    Miyake, S.4    Yamamoto, H.5    Fujinawa, R.6    Sugai, M.7    Okuno, Y.8    Tsujimoto, G.9    Yamaji, T.10
  • 44
    • 0035801948 scopus 로고    scopus 로고
    • Differential expression of GL7 activation antigen on bone marrow B cell subpopulations and peripheral B cells
    • Cervenak, L., A. Magyar, R. Boja, and G. László. 2001. Differential expression of GL7 activation antigen on bone marrow B cell subpopulations and peripheral B cells. Immunol. Lett. 78: 89-96.
    • (2001) Immunol. Lett. , vol.78 , pp. 89-96
    • Cervenak, L.1    Magyar, A.2    Boja, R.3    László, G.4
  • 45
    • 0027324869 scopus 로고
    • Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells
    • Laszlo, G., K. S. Hathcock, H. B. Dickler, and R. J. Hodes. 1993. Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells. J. Immunol. 150: 5252-5262. (Pubitemid 23180638)
    • (1993) Journal of Immunology , vol.150 , Issue.12 , pp. 5252-5262
    • Laszlo, G.1    Hathcock, K.S.2    Dickler, H.B.3    Hodes, R.J.4
  • 46
    • 33644749192 scopus 로고    scopus 로고
    • AID expression identifies interfollicular large B cells as putative precursors of mature B-cell malignancies
    • DOI 10.1182/blood-2005-06-2502
    • Moldenhauer, G., S. W. Popov, B. Wotschke, S. Brüderlein, P. Riedl, N. Fissolo, R. Schirmbeck, O. Ritz, P. Möller, and F. Leithäuser. 2006. AID expression identifies interfollicular large B cells as putative precursors of mature B-cell malignancies. Blood 107: 2470-2473. (Pubitemid 43345569)
    • (2006) Blood , vol.107 , Issue.6 , pp. 2470-2473
    • Moldenhauer, G.1    Popov, S.W.2    Wotschke, B.3    Bruderlein, S.4    Riedl, P.5    Fissolo, N.6    Schirmbeck, R.7    Ritz, O.8    Moller, P.9    Leithauser, F.10
  • 47
    • 33646596305 scopus 로고    scopus 로고
    • Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells
    • DOI 10.1182/blood-2005-10-4170
    • Cattoretti, G., M. Buettner, R. Shaknovich, E. Kremmer, B. Alobeid, and G. Niedobitek. 2006. Nuclear and cytoplasmic AID in extrafollicular and Germinal Center B cells. Blood 107: 3967-3975. (Pubitemid 43726803)
    • (2006) Blood , vol.107 , Issue.10 , pp. 3967-3975
    • Cattoretti, G.1    Buttner, M.2    Shaknovich, R.3    Kremmer, E.4    Alobeid, B.5    Niedobitek, G.6
  • 48
    • 43349091335 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjögren's syndrome
    • Bombardieri, M., F. Barone, F. Humby, S. Kelly, M. McGurk, P. Morgan, S. Challacombe, S. De Vita, G. Valesini, J. Spencer, and C. Pitzalis. 2007. Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjögren's syndrome. J. Immunol. 179: 4929-4938.
    • (2007) J. Immunol. , vol.179 , pp. 4929-4938
    • Bombardieri, M.1    Barone, F.2    Humby, F.3    Kelly, S.4    McGurk, M.5    Morgan, P.6    Challacombe, S.7    De Vita, S.8    Valesini, G.9    Spencer, J.10    Pitzalis, C.11
  • 49
    • 0035940511 scopus 로고    scopus 로고
    • A hallmark of active class switch recombination: Transcripts directed by I promoters on looped-out circular DNAs
    • Kinoshita, K., M. Harigai, S. Fagarasan, M. Muramatsu, and T. Honjo. 2001. A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs. Proc. Natl. Acad. Sci. USA 98: 12620-12623.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12620-12623
    • Kinoshita, K.1    Harigai, M.2    Fagarasan, S.3    Muramatsu, M.4    Honjo, T.5


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