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Volumn 107, Issue , 2018, Pages 130-135

Reduced dynamic range of antiviral innate immune responses in aging

Author keywords

Aging; Dendritic cell; Immunosenescence; Inflammasomes; Monocyte; RIG I

Indexed keywords

ALPHA INTERFERON; INFLAMMASOME; INTERLEUKIN 17; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PATTERN RECOGNITION RECEPTOR; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR; CYTOKINE;

EID: 85028350543     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2017.08.019     Document Type: Review
Times cited : (43)

References (79)
  • 1
    • 34249775503 scopus 로고    scopus 로고
    • Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway
    • Agrawal, A., Agrawal, S., Cao, J.N., Su, H., Osann, K., Gupta, S., Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J. Immunol. 178 (2007), 6912–6922.
    • (2007) J. Immunol. , vol.178 , pp. 6912-6922
    • Agrawal, A.1    Agrawal, S.2    Cao, J.N.3    Su, H.4    Osann, K.5    Gupta, S.6
  • 2
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S., Takeda, K., Toll-like receptor signalling. Nat. Rev. Immunol. 4 (2004), 499–511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 3
    • 84949724978 scopus 로고    scopus 로고
    • Inflammation, but not telomere length, predicts successful ageing at extreme old age: a longitudinal study of semi-supercentenarians
    • Arai, Y., Martin-Ruiz, C.M., Takayama, M., Abe, Y., Takebayashi, T., Koyasu, S., Suematsu, M., Hirose, N., von Zqlinicki, T., Inflammation, but not telomere length, predicts successful ageing at extreme old age: a longitudinal study of semi-supercentenarians. EBioMedicine 2 (2015), 1549–1558.
    • (2015) EBioMedicine , vol.2 , pp. 1549-1558
    • Arai, Y.1    Martin-Ruiz, C.M.2    Takayama, M.3    Abe, Y.4    Takebayashi, T.5    Koyasu, S.6    Suematsu, M.7    Hirose, N.8    von Zqlinicki, T.9
  • 4
    • 84989962589 scopus 로고    scopus 로고
    • Aging-associated TNF production primes inflammasome activation and NLRP3-related metabolic disturbances
    • Bauernfeind, F., Niepmann, S., Knolle, P.A., Hornung, V., Aging-associated TNF production primes inflammasome activation and NLRP3-related metabolic disturbances. J. Immunol. 197 (2016), 2900–2908.
    • (2016) J. Immunol. , vol.197 , pp. 2900-2908
    • Bauernfeind, F.1    Niepmann, S.2    Knolle, P.A.3    Hornung, V.4
  • 5
    • 0842309938 scopus 로고    scopus 로고
    • Age-dependent decrease in toll-like receptor 4-mediated proinflammatory cytokine production and mitogen-activated protein kinase expression
    • Boehmer, E.D., Goral, J., Faunce, D.E., Kovacs, E.J., Age-dependent decrease in toll-like receptor 4-mediated proinflammatory cytokine production and mitogen-activated protein kinase expression. J. Leukoc. Biol. 75 (2004), 342–349.
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 342-349
    • Boehmer, E.D.1    Goral, J.2    Faunce, D.E.3    Kovacs, E.J.4
  • 6
    • 27644480499 scopus 로고    scopus 로고
    • Aging negatively skews macrophage TLR2- and TLR4-mediated pro-inflammatory responses without affecting the IL-2-stimulated pathway
    • Boehmer, E.D., Meehan, M.J., Cutro, B.T., Kovacs, E.J., Aging negatively skews macrophage TLR2- and TLR4-mediated pro-inflammatory responses without affecting the IL-2-stimulated pathway. Mech. Ageing Dev. 126 (2005), 1305–1313.
    • (2005) Mech. Ageing Dev. , vol.126 , pp. 1305-1313
    • Boehmer, E.D.1    Meehan, M.J.2    Cutro, B.T.3    Kovacs, E.J.4
  • 7
    • 33846798524 scopus 로고    scopus 로고
    • Age-related differences in pulmonary cytokine response to respiratory syncytial virus infection: modulation by anti-inflammatory and antiviral treatment
    • Boukhvalova, M.S., Yim, K.C., Kuhn, K.H., Hemming, J.P., Prince, G.A., Porter, D.D., Blanco, J.C., Age-related differences in pulmonary cytokine response to respiratory syncytial virus infection: modulation by anti-inflammatory and antiviral treatment. J Infect Dis 195 (2007), 511–518.
    • (2007) J Infect Dis , vol.195 , pp. 511-518
    • Boukhvalova, M.S.1    Yim, K.C.2    Kuhn, K.H.3    Hemming, J.P.4    Prince, G.A.5    Porter, D.D.6    Blanco, J.C.7
  • 8
    • 84927639135 scopus 로고    scopus 로고
    • Innate immune pattern recognition: a cell biological perspective
    • Brubaker, S.W., Bonham, K.S., Zanoni, I., Kagan, J.C., Innate immune pattern recognition: a cell biological perspective. Annu. Rev. Immunol. 33 (2015), 257–290.
    • (2015) Annu. Rev. Immunol. , vol.33 , pp. 257-290
    • Brubaker, S.W.1    Bonham, K.S.2    Zanoni, I.3    Kagan, J.C.4
  • 12
    • 84991660928 scopus 로고    scopus 로고
    • Evidence for a limit to human lifespan
    • Dong, X., Milholland, B., Vijg, J., Evidence for a limit to human lifespan. Nature 538 (2016), 257–259.
    • (2016) Nature , vol.538 , pp. 257-259
    • Dong, X.1    Milholland, B.2    Vijg, J.3
  • 16
    • 84941811337 scopus 로고    scopus 로고
    • New approaches to understanding the immune response to vaccination and infection
    • Furman, D., Davis, M.M., New approaches to understanding the immune response to vaccination and infection. Vaccine 33 (2015), 5271–5281.
    • (2015) Vaccine , vol.33 , pp. 5271-5281
    • Furman, D.1    Davis, M.M.2
  • 20
    • 59749106107 scopus 로고    scopus 로고
    • Elie Metchnikoff: father of natural immunity
    • Gordon, S., Elie Metchnikoff: father of natural immunity. Eur. J. Immunol. 38 (2008), 3257–3264.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 3257-3264
    • Gordon, S.1
  • 21
    • 84857415635 scopus 로고    scopus 로고
    • Constitutive type I interferon modulates homeostatic balance through tonic signaling
    • Gough, D.J., Messina, N.L., Clarke, C.J., Johnstone, R.W., Levy, D.E., Constitutive type I interferon modulates homeostatic balance through tonic signaling. Immunity 36 (2012), 166–174.
    • (2012) Immunity , vol.36 , pp. 166-174
    • Gough, D.J.1    Messina, N.L.2    Clarke, C.J.3    Johnstone, R.W.4    Levy, D.E.5
  • 22
    • 84898913236 scopus 로고    scopus 로고
    • A review of the epidemiological and clinical aspects of West Nile virus
    • Gray, T.J., Webb, C.E., A review of the epidemiological and clinical aspects of West Nile virus. Int. J. Gen. Med. 7 (2014), 193–203.
    • (2014) Int. J. Gen. Med. , vol.7 , pp. 193-203
    • Gray, T.J.1    Webb, C.E.2
  • 23
    • 84997751528 scopus 로고    scopus 로고
    • The AIM2-like receptors are dispensable for the interferon response to intracellular DNA
    • Gray, E.E., Winship, D., Snyder, J.M., Child, S.J., Geballe, A.P., Stetson, D.B., The AIM2-like receptors are dispensable for the interferon response to intracellular DNA. Immunity 45 (2016), 255–266.
    • (2016) Immunity , vol.45 , pp. 255-266
    • Gray, E.E.1    Winship, D.2    Snyder, J.M.3    Child, S.J.4    Geballe, A.P.5    Stetson, D.B.6
  • 24
    • 84936891896 scopus 로고    scopus 로고
    • Inflammasomes: mechanism of action, role in disease, and therapeutics
    • Guo, H., Callaway, J.B., Ting, J.P.Y., Inflammasomes: mechanism of action, role in disease, and therapeutics. Nat. Med. 21 (2015), 677–687.
    • (2015) Nat. Med. , vol.21 , pp. 677-687
    • Guo, H.1    Callaway, J.B.2    Ting, J.P.Y.3
  • 25
    • 0018869587 scopus 로고
    • Host gene influences sensitivity to interferon action selectively for influenza virus
    • Haller, O., Arnheiter, H., Lindenmann, J., Gresser, I., Host gene influences sensitivity to interferon action selectively for influenza virus. Nature 283 (1980), 660–662.
    • (1980) Nature , vol.283 , pp. 660-662
    • Haller, O.1    Arnheiter, H.2    Lindenmann, J.3    Gresser, I.4
  • 27
  • 31
    • 70349303199 scopus 로고    scopus 로고
    • Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood
    • Jing, Y., Shaheen, E., Drake, R.R., Chen, N., Gravenstein, S., Deng, Y., Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood. Hum. Immunol. 70 (2009), 777–784.
    • (2009) Hum. Immunol. , vol.70 , pp. 777-784
    • Jing, Y.1    Shaheen, E.2    Drake, R.R.3    Chen, N.4    Gravenstein, S.5    Deng, Y.6
  • 32
    • 34248672889 scopus 로고    scopus 로고
    • Antiviral signaling through pattern recognition receptors
    • Kawai, T., Akira, S., Antiviral signaling through pattern recognition receptors. J. Biochem. 141 (2007), 137–145.
    • (2007) J. Biochem. , vol.141 , pp. 137-145
    • Kawai, T.1    Akira, S.2
  • 35
    • 84937125049 scopus 로고    scopus 로고
    • New insights into innate immune restriction of West Nile virus infection
    • Lazear, H.M., Diamond, M.S., New insights into innate immune restriction of West Nile virus infection. Curr. Opin. Virol. 11 (2015), 1–6.
    • (2015) Curr. Opin. Virol. , vol.11 , pp. 1-6
    • Lazear, H.M.1    Diamond, M.S.2
  • 40
    • 84991463632 scopus 로고    scopus 로고
    • Age-related alterations in immune responses to West Nile virus infection
    • Montgomery, R.R., Age-related alterations in immune responses to West Nile virus infection. Clin. Exp. Immunol. 187 (2017), 26–34.
    • (2017) Clin. Exp. Immunol. , vol.187 , pp. 26-34
    • Montgomery, R.R.1
  • 41
    • 84923050029 scopus 로고    scopus 로고
    • Risk factors for West Nile virus infection and disease in populations and individuals
    • Montgomery, R.R., Murray, K.O., Risk factors for West Nile virus infection and disease in populations and individuals. Expert Rev. Anti-Infect. Ther. 13 (2015), 317–325.
    • (2015) Expert Rev. Anti-Infect. Ther. , vol.13 , pp. 317-325
    • Montgomery, R.R.1    Murray, K.O.2
  • 43
    • 78651275576 scopus 로고    scopus 로고
    • Impaired functions of peripheral blood monocyte subpopulations in aged humans
    • Nyugen, J., Agrawal, S., Gollapudi, S., Gupta, S., Impaired functions of peripheral blood monocyte subpopulations in aged humans. J. Clin. Immunol. 30 (2010), 806–813.
    • (2010) J. Clin. Immunol. , vol.30 , pp. 806-813
    • Nyugen, J.1    Agrawal, S.2    Gollapudi, S.3    Gupta, S.4
  • 45
    • 78650754831 scopus 로고    scopus 로고
    • Inflammasomes as mediators of immunity against influenza virus
    • Pang, I.K., Iwasaki, A., Inflammasomes as mediators of immunity against influenza virus. Trends Immunol. 32 (2011), 34–41.
    • (2011) Trends Immunol. , vol.32 , pp. 34-41
    • Pang, I.K.1    Iwasaki, A.2
  • 48
    • 84892580313 scopus 로고    scopus 로고
    • Impaired secretion of interferons by dendritic cells from aged subjects to influenza: role of histone modifications
    • Prakash, S., Agrawal, S., Cao, J.-n.; Gupta, S.; Agrawal, A., Impaired secretion of interferons by dendritic cells from aged subjects to influenza: role of histone modifications. Age 35 (2013), 1785–1797.
    • (2013) Age , vol.35 , pp. 1785-1797
    • Prakash, S.1    Agrawal, S.2    Cao, J.-n.3    Gupta, S.4    Agrawal, A.,5
  • 49
    • 79955001064 scopus 로고    scopus 로고
    • Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus
    • Qian, F., Wang, X., Zhang, L., Lin, A., Zhao, H., Fikrig, E., Montgomery, R.R., Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus. J Infect Dis 203 (2011), 1415–1424.
    • (2011) J Infect Dis , vol.203 , pp. 1415-1424
    • Qian, F.1    Wang, X.2    Zhang, L.3    Lin, A.4    Zhao, H.5    Fikrig, E.6    Montgomery, R.R.7
  • 53
    • 67149091317 scopus 로고    scopus 로고
    • Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon–dependent exhaustion
    • Sato, T., Onai, N., Yoshihara, H., Arai, F., Suda, T., Ohteki, T., Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon–dependent exhaustion. Nat. Med. 15 (2009), 696–700.
    • (2009) Nat. Med. , vol.15 , pp. 696-700
    • Sato, T.1    Onai, N.2    Yoshihara, H.3    Arai, F.4    Suda, T.5    Ohteki, T.6
  • 56
    • 80655125143 scopus 로고    scopus 로고
    • Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity
    • Sridharan, A., Esposo, M., Kaushal, K., Tay, J., Osann, K., Agrawal, S., Gupta, S., Agrawal, A., Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity. Age (Dordr.) 33 (2011), 363–376.
    • (2011) Age (Dordr.) , vol.33 , pp. 363-376
    • Sridharan, A.1    Esposo, M.2    Kaushal, K.3    Tay, J.4    Osann, K.5    Agrawal, S.6    Gupta, S.7    Agrawal, A.8
  • 58
    • 58149177781 scopus 로고    scopus 로고
    • Aging impairs IFN regulatory factor 7 upregulation in plasmacytoid dendritic cells during TLR9 activation
    • Stout-Delgado, H.W., Yang, X., Walker, W.E., Tesar, B.M., Goldstein, D.R., Aging impairs IFN regulatory factor 7 upregulation in plasmacytoid dendritic cells during TLR9 activation. J. Immunol. 181 (2008), 6747–6756.
    • (2008) J. Immunol. , vol.181 , pp. 6747-6756
    • Stout-Delgado, H.W.1    Yang, X.2    Walker, W.E.3    Tesar, B.M.4    Goldstein, D.R.5
  • 59
    • 71749111987 scopus 로고    scopus 로고
    • Aging promotes neutrophil-induced mortality by augmenting IL-17 production during viral infection
    • Stout-Delgado, H.W., Du, W., Shirali, A.C., Booth, C.J., Goldstein, D.R., Aging promotes neutrophil-induced mortality by augmenting IL-17 production during viral infection. Cell Host Microbe 6 (2009), 446–456.
    • (2009) Cell Host Microbe , vol.6 , pp. 446-456
    • Stout-Delgado, H.W.1    Du, W.2    Shirali, A.C.3    Booth, C.J.4    Goldstein, D.R.5
  • 60
    • 84857866008 scopus 로고    scopus 로고
    • Impaired NLRP3 inflammasome function in elderly mice during influenza infection is rescued by treatment with nigericin
    • Stout-Delgado, H.W., Vaughan, S.E., Shirali, A.C., Jaramillo, R.J., Harrod, K.S., Impaired NLRP3 inflammasome function in elderly mice during influenza infection is rescued by treatment with nigericin. J. Immunol. 188 (2012), 2815–2824.
    • (2012) J. Immunol. , vol.188 , pp. 2815-2824
    • Stout-Delgado, H.W.1    Vaughan, S.E.2    Shirali, A.C.3    Jaramillo, R.J.4    Harrod, K.S.5
  • 61
    • 84959500135 scopus 로고    scopus 로고
    • The mitochondrial basis of aging
    • Sun, N., Youle, Richard J., Finkel, T., The mitochondrial basis of aging. Mol. Cell 61 (2016), 654–666.
    • (2016) Mol. Cell , vol.61 , pp. 654-666
    • Sun, N.1    Youle, R.J.2    Finkel, T.3
  • 62
    • 79959736816 scopus 로고    scopus 로고
    • Induction of a potent immune response in the elderly using the TLR-5 agonist, flagellin, with a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125, STF2.HA1 SI)
    • Taylor, D.N., Treanor, J.J., Strout, C., Johnson, C., Fitzgerald, T., Kavita, U., Ozer, K., Tussey, L., Shaw, A., Induction of a potent immune response in the elderly using the TLR-5 agonist, flagellin, with a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125, STF2.HA1 SI). Vaccine 29 (2011), 4897–4902.
    • (2011) Vaccine , vol.29 , pp. 4897-4902
    • Taylor, D.N.1    Treanor, J.J.2    Strout, C.3    Johnson, C.4    Fitzgerald, T.5    Kavita, U.6    Ozer, K.7    Tussey, L.8    Shaw, A.9
  • 63
    • 0037425564 scopus 로고    scopus 로고
    • Mortality associated with influenza and respiratory syncytial virus in the United States
    • Thompson, W.W., Shay, D.K., Weintraub, E., Brammer, L., Cox, N., Anderson, L.J., Fukuda, K., Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 289 (2003), 179–186.
    • (2003) JAMA , vol.289 , pp. 179-186
    • Thompson, W.W.1    Shay, D.K.2    Weintraub, E.3    Brammer, L.4    Cox, N.5    Anderson, L.J.6    Fukuda, K.7
  • 64
    • 73949091048 scopus 로고    scopus 로고
    • Impaired immune responses in the lungs of aged mice following influenza infection
    • Toapanta, F.R., Ross, T.M., Impaired immune responses in the lungs of aged mice following influenza infection. Respir. Res. 10 (2009), 112–131.
    • (2009) Respir. Res. , vol.10 , pp. 112-131
    • Toapanta, F.R.1    Ross, T.M.2
  • 65
    • 84900395915 scopus 로고    scopus 로고
    • Expanding roles of neutrophils in aging hosts
    • Tseng, C.W., Liu, G.Y., Expanding roles of neutrophils in aging hosts. Curr. Opin. Immunol. 29 (2014), 43–48.
    • (2014) Curr. Opin. Immunol. , vol.29 , pp. 43-48
    • Tseng, C.W.1    Liu, G.Y.2
  • 72
    • 85026266412 scopus 로고    scopus 로고
    • Aging impairs alveolar macrophage phagocytosis and increases influenza-induced mortality in mice
    • Wong, C.K., A., S.C., Sakamoto, S., Kaminski, N., Koff, J.L., Goldstein, D.R., Aging impairs alveolar macrophage phagocytosis and increases influenza-induced mortality in mice. J. Immunol. 199 (2017), 1060–1068.
    • (2017) J. Immunol. , vol.199 , pp. 1060-1068
    • Wong, C.K.1    A., S.C.2    Sakamoto, S.3    Kaminski, N.4    Koff, J.L.5    Goldstein, D.R.6
  • 74
    • 84979210572 scopus 로고    scopus 로고
    • Role of immune aging in susceptibility to West Nile virus
    • (Clifton, NJ)
    • Yao, Y., Montgomery, R.R., Role of immune aging in susceptibility to West Nile virus. Methods Mol. Biol. 1435 (2016), 235–247 (Clifton, NJ).
    • (2016) Methods Mol. Biol. , vol.1435 , pp. 235-247
    • Yao, Y.1    Montgomery, R.R.2
  • 75
  • 79
    • 84055190787 scopus 로고    scopus 로고
    • Age-related increases in PGD2 expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice
    • Zhao, J., Zhao, J., Legge, K., Perlman, S., Age-related increases in PGD2 expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice. J. Clin. Invest., 121, 2011, 4921.
    • (2011) J. Clin. Invest. , vol.121 , pp. 4921
    • Zhao, J.1    Zhao, J.2    Legge, K.3    Perlman, S.4


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