-
1
-
-
0028983212
-
Ig vh hypermutation is absent in the germinal centers of aged mice
-
PMID: 7561032
-
Miller C, Kelsoe G (1995) Ig VH hypermutation is absent in the germinal centers of aged mice. J Immunol 155: 3377-3384. PMID: 7561032.
-
(1995)
J Immunol
, vol.155
, pp. 3377-3384
-
-
Miller, C.1
Kelsoe, G.2
-
2
-
-
0029918498
-
Relative contribution of t and b cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice
-
PMID: 8642299
-
Yang X, Stedra J, Cerny J (1996) Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice. J Exp Med 183: 959-970. PMID: 8642299.
-
(1996)
J Exp Med
, vol.183
, pp. 959-970
-
-
Yang, X.1
Stedra, J.2
Cerny, J.3
-
3
-
-
84857416171
-
Maintenance of peripheral naive t cells is sustained by thymus output in mice but not humans
-
PMID: 22365666
-
Braber den I, Mugwagwa T, Vrisekoop N, Westera L, Mögling R, Bregje de Boer A, et al. (2012) Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans. Immunity 36: 288-297. doi:10.1016/j.immuni.2012.02.006 PMID: 22365666.
-
(2012)
Immunity
, vol.36
, pp. 288-297
-
-
Den Braber, I.1
Mugwagwa, T.2
Vrisekoop, N.3
Westera, L.4
Mögling, R.5
De Bregje, B.A.6
-
4
-
-
84055200841
-
Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
-
Pang WW, Price EA, Sahoo D, Beerman I, Maloney WJ, Rossi DJ, et al. (2011) Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. Proceedings of the National Academy of Sciences 108: 20012-20017. doi:10.1073/pnas.1116110108.
-
(2011)
Proceedings of the National Academy of Sciences
, vol.108
, pp. 20012-20017
-
-
Pang, W.W.1
Price, E.A.2
Sahoo, D.3
Beerman, I.4
Maloney, W.J.5
Rossi, D.J.6
-
5
-
-
77950418688
-
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
-
Beerman I, Bhattacharya D, Zandi S, Sigvardsson M, Weissman IL, Bryder D, et al. (2010) Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proceedings of the National Academy of Sciences 107: 5465-5470. doi:10.1073/pnas.1000834107.
-
(2010)
Proceedings of the National Academy of Sciences
, vol.107
, pp. 5465-5470
-
-
Beerman, I.1
Bhattacharya, D.2
Zandi, S.3
Sigvardsson, M.4
Weissman, I.L.5
Bryder, D.6
-
6
-
-
50149099346
-
Acquired hematopoietic stem cell defects determine b-cell repertoire changes associated with aging
-
Guerrettaz LM, Johnson SA, Cambier JC (2008) Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging. Proceedings of the National Academy of Sciences 105: 11898-11902. doi:10.1073/pnas.0805498105.
-
(2008)
Proceedings of the National Academy of Sciences
, vol.105
, pp. 11898-11902
-
-
Guerrettaz, L.M.1
Johnson, S.A.2
Cambier, J.C.3
-
7
-
-
84892778834
-
Effects of aging, cytomegalovirus infection, and ebv infection on human b cell repertoires
-
Wang C, Liu Y, Xu LT, Jackson KJL, Roskin KM, Pham TD, et al. (2014) Effects of Aging, Cytomegalovirus Infection, and EBV Infection on Human B Cell Repertoires. J Immunol.
-
(2014)
J Immunol
-
-
Wang, C.1
Liu, Y.2
Xu, L.T.3
Jackson, K.J.L.4
Roskin, K.M.5
Pham, T.D.6
-
8
-
-
80053516103
-
Functional cd8 t cell memory responding to persistent latent infection is maintained for life
-
PMID: 21890658
-
Lang A, Nikolich-Zugich J (2011) Functional CD8 T cell memory responding to persistent latent infection is maintained for life. The Journal of Immunology 187: 3759-3768. doi:10.4049/jimmunol.1100666 PMID: 21890658.
-
(2011)
The Journal of Immunology
, vol.187
, pp. 3759-3768
-
-
Lang, A.1
Nikolich-Zugich, J.2
-
9
-
-
84902745196
-
High-dimensional analysis of the aging immune system: Verification of age-associated differences in immune signaling responses in healthy donors
-
PMID: 24952610
-
Longo DM, Louie B, Ptacek J, Friedland G, Evensen E, Putta S, et al. (2014) High-dimensional analysis of the aging immune system: Verification of age-associated differences in immune signaling responses in healthy donors. J Transl Med 12: 178. doi:10.1186/1479-5876-12-178 PMID: 24952610.
-
(2014)
J Transl Med
, vol.12
, pp. 178
-
-
Longo, D.M.1
Louie, B.2
Ptacek, J.3
Friedland, G.4
Evensen, E.5
Putta, S.6
-
10
-
-
84859574715
-
Signal inhibition by the dual-specific phosphatase 4 impairs t cell-dependent b-cell responses with age
-
Yu M, Li G, Lee W-W, Yuan M, Cui D, Weyand CM, et al. (2012) Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age. Proceedings of the National Academy of Sciences 109: E879-E888doi:10.1073/pnas.1109797109.
-
(2012)
Proceedings of the National Academy of Sciences
, vol.109
, pp. E879-E888
-
-
Yu, M.1
Li, G.2
Lee, W.-W.3
Yuan, M.4
Cui, D.5
Weyand, C.M.6
-
12
-
-
67649407892
-
Cd28(-) t cells: Their role in the age-associated decline of immune function
-
PMID: 19540809
-
Weng N- P, Akbar AN, Goronzy J (2009) CD28(-) T cells: Their role in the age-associated decline of immune function. Trends in Immunology 30: 306-312. doi:10.1016/j.it.2009.03.013 PMID: 19540809.
-
(2009)
Trends in Immunology
, vol.30
, pp. 306-312
-
-
Weng, N.-P.1
Akbar, A.N.2
Goronzy, J.3
-
13
-
-
84868213167
-
Finding balance: T cell regulatory receptor expression during aging
-
PMID: 22396890
-
Cavanagh MM, Qi Q, Weyand CM, Goronzy JJ (2011) Finding Balance: T cell Regulatory Receptor Expression during Aging. Aging Dis 2: 398-413. PMID: 22396890.
-
(2011)
Aging Dis
, vol.2
, pp. 398-413
-
-
Cavanagh, M.M.1
Qi, Q.2
Weyand, C.M.3
Goronzy, J.J.4
-
14
-
-
33748752794
-
Il-2 production correlates with effector cell differentiation in HIV-specific cd8+ t cells
-
PMID: 16859558
-
Nomura LE, Emu B, Hoh R, Haaland P, Deeks SG, Martin JM, et al. (2006) IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells. AIDS Res Ther 3: 18. doi:10.1186/1742-6405-3-18 PMID: 16859558.
-
(2006)
AIDS Res Ther
, vol.3
, pp. 18
-
-
Nomura, L.E.1
Emu, B.2
Hoh, R.3
Haaland, P.4
Deeks, S.G.5
Martin, J.M.6
-
15
-
-
62749134469
-
Comparisons of cd8+ t cells specific for human immunodeficiency virus, hepatitis c virus, and cytomegalovirus reveal differences in frequency, immunodominance, phenotype, and interleukin-2 responsiveness
-
PMID: 19129459
-
Jagannathan P, Osborne CM, Royce C, Manion MM, Tilton JC, Fischer S, et al. (2009) Comparisons of CD8+ T Cells Specific for Human Immunodeficiency Virus, Hepatitis C Virus, and Cytomegalovirus Reveal Differences in Frequency, Immunodominance, Phenotype, and Interleukin-2 Responsiveness. Journal of Virology 83: 2728-2742. doi:10.1128/JVI.02128-08 PMID: 19129459.
-
(2009)
Journal of Virology
, vol.83
, pp. 2728-2742
-
-
Jagannathan, P.1
Osborne, C.M.2
Royce, C.3
Manion, M.M.4
Tilton, J.C.5
Fischer, S.6
-
16
-
-
0036109159
-
Memory cd8+ t cells vary in differentiation phenotype in different persistent virus infections
-
PMID: 11927944
-
Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GMA, Papagno L, et al. (2002) Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nat Med 8: 379-385. doi:10.1038/nm0402-379 PMID: 11927944.
-
(2002)
Nat Med
, vol.8
, pp. 379-385
-
-
Appay, V.1
Dunbar, P.R.2
Callan, M.3
Klenerman, P.4
Gillespie, G.M.A.5
Papagno, L.6
-
17
-
-
84896348458
-
Impact of HIV on cd8+ t cell cd57 expression is distinct from that of cmv and aging
-
PMID: 24586783
-
Lee SA, Sinclair E, Hatano H, Hsue PY, Epling L, Hecht FM, et al. (2014) Impact of HIV on CD8+ T Cell CD57 Expression Is Distinct from That of CMV and Aging. PLoS ONE 9: e89444. doi:10.1371/journal.pone.0089444 PMID: 24586783.
-
(2014)
PLoS ONE
, vol.9
, pp. e89444
-
-
Lee, S.A.1
Sinclair, E.2
Hatano, H.3
Hsue, P.Y.4
Epling, L.5
Hecht, F.M.6
-
18
-
-
77951637832
-
Cytomegalovirus infection reduces telomere length of the circulating t cell pool
-
PMID: 20176738
-
van de Berg PJEJ, Griffiths SJ, Yong S-L, Macaulay R, Bemelman FJ, Jackson S, et al. (2010) Cytomegalovirus infection reduces telomere length of the circulating T cell pool. The Journal of Immunology 184: 3417-3423. doi:10.4049/jimmunol.0903442 PMID: 20176738.
-
(2010)
The Journal of Immunology
, vol.184
, pp. 3417-3423
-
-
Van De Berg, P.J.E.J.1
Griffiths, S.J.2
Yong, S.-L.3
Macaulay, R.4
Bemelman, F.J.5
Jackson, S.6
-
19
-
-
0037103256
-
Cytomegalovirus seropositivity drives the cd8 t cell repertoire toward greater clonality in healthy elderly individuals
-
PMID: 12165524
-
Khan N, Shariff N, Cobbold M, Bruton R, Ainsworth JA, Sinclair AJ, et al. (2002) Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals. J Immunol 169: 1984-1992. PMID: 12165524.
-
(2002)
J Immunol
, vol.169
, pp. 1984-1992
-
-
Khan, N.1
Shariff, N.2
Cobbold, M.3
Bruton, R.4
Ainsworth, J.A.5
Sinclair, A.J.6
-
20
-
-
68149148869
-
Biomarkers of human immunosenescence: Impact of cytomegalovirus infection
-
PMID: 19535233
-
Derhovanessian E, Larbi A, Pawelec G (2009) Biomarkers of human immunosenescence: impact of Cytomegalovirus infection. Curr Opin Immunol 21: 440-445. doi:10.1016/j.coi.2009.05.012 PMID: 19535233.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 440-445
-
-
Derhovanessian, E.1
Larbi, A.2
Pawelec, G.3
-
21
-
-
77955409169
-
Elevated serum chemokine cxc ligand 5 levels are associated with hypercholesterolemia but not a worsening of insulin resistance in Chinese people
-
Yang Z, Zhang Z, Wen J, Wang X, Lu B, Yang Z, et al. (2010) Elevated Serum Chemokine CXC Ligand 5 Levels Are Associated with Hypercholesterolemia But Not a Worsening of Insulin Resistance in Chinese People. Journal of Clinical Endocrinology & Metabolism 95: 3926-3932. doi:10.1210/jc.2009-2194.
-
(2010)
Journal of Clinical Endocrinology & Metabolism
, vol.95
, pp. 3926-3932
-
-
Yang, Z.1
Zhang, Z.2
Wen, J.3
Wang, X.4
Lu, B.5
Yang, Z.6
-
22
-
-
0030768120
-
Plasma leptin concentrations: Gender differences and associations with metabolic risk factors for cardiovascular disease
-
PMID: 9349599
-
Couillard C, Mauriège P, Prud'homme D, Nadeau A, Tremblay A, Bouchard C, et al. (1997) Plasma leptin concentrations: gender differences and associations with metabolic risk factors for cardiovascular disease. Diabetologia 40: 1178-1184. doi:10.1007/s001250050804 PMID: 9349599.
-
(1997)
Diabetologia
, vol.40
, pp. 1178-1184
-
-
Couillard, C.1
Mauriège, P.2
Prud'homme, D.3
Nadeau, A.4
Tremblay, A.5
Bouchard, C.6
-
23
-
-
41949097070
-
Pilot study of sex differences in chemokine/cytokine markers of atherosclerosis in humans
-
PMID: 18420165
-
Leung J, Jayachandran M, Kendall-Thomas J, Behrenbeck T, Araoz P, Miller VM. (2008) Pilot study of sex differences in chemokine/cytokine markers of atherosclerosis in humans. Gend Med 5: 44-52. PMID: 18420165.
-
(2008)
Gend Med
, vol.5
, pp. 44-52
-
-
Leung, J.1
Jayachandran, M.2
Kendall-Thomas, J.3
Behrenbeck, T.4
Araoz, P.5
Miller, V.M.6
-
24
-
-
79955635289
-
Sex differences in survival of cutaneous melanoma are age dependent: An analysis of 7338 patients
-
PMID: 21540649
-
Mervic L, Leiter U, Meier F, Eigentler T, Forschner A, Metzler G, et al. (2011) Sex differences in survival of cutaneous melanoma are age dependent: An analysis of 7338 patients. Melanoma Res 21: 244- 252. doi:10.1097/CMR.0b013e32834577c8 PMID: 21540649.
-
(2011)
Melanoma Res
, vol.21
, pp. 244-252
-
-
Mervic, L.1
Leiter, U.2
Meier, F.3
Eigentler, T.4
Forschner, A.5
Metzler, G.6
-
25
-
-
84883033569
-
Sex is an independent prognostic indicator for survIVal and relapse/progression-free survIVal in metastasized stage III to IV melanoma: A pooled analysis of fIVe european organisation for research and treatment of cancer randomized controlled trials
-
PMID: 23690423
-
Joosse A, Collette S, Suciu S, Nijsten T, Patel PM, Keilholz U, et al. (2013) Sex is an independent prognostic indicator for survival and relapse/progression-free survival in metastasized stage III to IV melanoma: A pooled analysis of five European organisation for research and treatment of cancer randomized controlled trials. J Clin Oncol 31: 2337-2346. doi:10.1200/JCO.2012.44.5031 PMID: 23690423.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2337-2346
-
-
Joosse, A.1
Collette, S.2
Suciu, S.3
Nijsten, T.4
Patel, P.M.5
Keilholz, U.6
-
26
-
-
16244401458
-
Regularization and variable selection via the elastic net
-
Zou H, Hastie T (2005) Regularization and variable selection via the elastic net. J Royal Stat Soc Series B (Methodological) 67: 301-320.
-
(2005)
J Royal Stat Soc Series B Methodological
, vol.67
, pp. 301-320
-
-
Zou, H.1
Hastie, T.2
-
27
-
-
0036642408
-
Dynamics of cd4 and cd8 t cell responses to cytomegalovirus in healthy human donors
-
PMID: 12089657
-
Dunn HS, Haney DJ, Ghanekar SA, Stepick-Biek PP, Lewis DB, Maecker HT. (2002) Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors. J Infect Dis 186: 15-22. doi:10.1086/341079 PMID: 12089657.
-
(2002)
J Infect Dis
, vol.186
, pp. 15-22
-
-
Dunn, H.S.1
Haney, D.J.2
Ghanekar, S.A.3
Stepick-Biek, P.P.4
Lewis, D.B.5
Maecker, H.T.6
-
28
-
-
84920982264
-
Variation in the human immune system is largely driven by non-heritable influences
-
PMID: 25594173
-
Brodin P, Jojic V, Gao T, Bhattacharya S, Angel CJL, Furman D, et al. (2015) Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences. Cell 160: 37-47. doi:10.1016/j.cell.2014.12.020 PMID: 25594173.
-
(2015)
Cell
, vol.160
, pp. 37-47
-
-
Brodin, P.1
Jojic, V.2
Gao, T.3
Bhattacharya, S.4
Angel, C.J.L.5
Furman, D.6
-
30
-
-
0022119886
-
A simple method to assess exercise behavior in the community
-
PMID: 4053261
-
Godin G, Shephard RJ (1985) A simple method to assess exercise behavior in the community. Can J Appl Sport Sci 10: 141-146. PMID: 4053261.
-
(1985)
Can J Appl Sport Sci
, vol.10
, pp. 141-146
-
-
Godin, G.1
Shephard, R.J.2
-
31
-
-
24044485648
-
A global clinical measure of fitness and frailty in elderly people
-
PMID: 16129869
-
Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, et al. (2005) A global clinical measure of fitness and frailty in elderly people. CMAJ 173: 489-495. doi:10.1503/cmaj.050051 PMID: 16129869.
-
(2005)
CMAJ
, vol.173
, pp. 489-495
-
-
Rockwood, K.1
Song, X.2
MacKnight, C.3
Bergman, H.4
Hogan, D.B.5
McDowell, I.6
-
32
-
-
2442699834
-
Frailty in older adults: Evidence for a phenotype
-
PMID: 11253156
-
Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56: M146-M156. PMID: 11253156.
-
(2001)
J Gerontol a Biol Sci Med Sci
, vol.56
, pp. M146-M156
-
-
Fried, L.P.1
Tangen, C.M.2
Walston, J.3
Newman, A.B.4
Hirsch, C.5
Gottdiener, J.6
|