Aging impairs alveolar macrophage phagocytosis and increases influenza-induced mortality in mice

Journal of Immunology

Volumn 199, Issue 3, 2017, Pages 1060-1068

  Wong, Christine K ^a   Smith, Candice A ^b   Sakamoto, Koji ^a   Kaminski, Naftali ^a   Koff, Jonathan L ^a   Goldstein, Daniel R ^a,b,c,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD204 ANTIGEN; CLODRONIC ACID; SCAVENGER RECEPTOR; UNCLASSIFIED DRUG; MSR1 PROTEIN, MOUSE; SCAVENGER RECEPTOR A;

ADOPTIVE TRANSFER; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CELL FUNCTION; CELL SELECTION; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; INFLUENZA; JUVENILE ANIMAL; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; MORBIDITY; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; VIRUS LOAD; ANIMAL; CELL CYCLE; DISEASE MODEL; GENETICS; HUMAN; IMMUNOLOGY; INFLUENZA A VIRUS (H1N1); LUNG; METABOLISM; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; VIROLOGY;

AGING; ANIMALS; CELL CYCLE; DISEASE MODELS, ANIMAL; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; LUNG; MACROPHAGES, ALVEOLAR; MICE; NEUTROPHILS; ORTHOMYXOVIRIDAE INFECTIONS; PHAGOCYTOSIS; SCAVENGER RECEPTORS, CLASS A;

EID: 85026266412     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1700397     Document Type: Article

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