Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

Nature Genetics

Volumn 14, Issue 2, 1996, Pages 141-145

  Whitcomb, David C ^a,b   Gorry, Michael C ^a   Preston, Robert A ^a   Furey, William ^b   Sossenheimer, Michael J ^a   Ulrich, Charles D ^c   Martin, Stephen P ^c   Gates Jr , Lawrence K ^d   Amann, Stephen T ^e   Toskes, Phillip P ^e   Liddle, Roger ^f   McGrath, Kevin ^f   Uomo, G ^g   Post, J C ^a,h   Ehrlich, Garth D ^a,h  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CINCINNATI   (United States)

^d UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

^g CARDARELLI HOSPITAL   (Italy)

^h CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REPETITIVE DNA;

ARTICLE; CRYSTAL STRUCTURE; EPIGASTRIC PAIN; GENE ISOLATION; GENE MUTATION; GENETIC MARKER; HEREDITY; HUMAN; HUMAN CELL; MOLECULAR MODEL; PANCREATITIS; PRIORITY JOURNAL; X RAY ANALYSIS;

ARGININE; CHROMOSOMES, HUMAN, PAIR 7; DNA MUTATIONAL ANALYSIS; ENZYME ACTIVATION; EXONS; FEMALE; GENES; HETEROZYGOTE; HUMANS; MALE; MODELS, MOLECULAR; PANCREATITIS; PEDIGREE; POINT MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; TRYPSIN; TRYPSINOGEN;

EID: 10144246566     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1096-141     Document Type: Article

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