메뉴 건너뛰기




Volumn 147, Issue , 2018, Pages 565-579

Pharmaceutical and biomedical analysis of cannabinoids: A critical review

Author keywords

Cannabinoids; Cannabis; Gas chromatography; Liquid chromatography

Indexed keywords

CANNABINOID DERIVATIVE; CANNABIS; CANNABINOID; DRUG; MEDICAL CANNABIS;

EID: 85020846586     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2017.06.003     Document Type: Review
Times cited : (201)

References (130)
  • 1
    • 70849088937 scopus 로고    scopus 로고
    • Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material
    • De Backer, B., Debrus, B., Lebrun, P., Theunis, L., Dubois, N., Decock, L., Verstraete, A., Hubert, P., Charlier, C., Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 877 (2009), 4115–4124, 10.1016/j.jchromb.2009.11.004.
    • (2009) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.877 , pp. 4115-4124
    • De Backer, B.1    Debrus, B.2    Lebrun, P.3    Theunis, L.4    Dubois, N.5    Decock, L.6    Verstraete, A.7    Hubert, P.8    Charlier, C.9
  • 2
    • 78249276186 scopus 로고    scopus 로고
    • Metabolic fingerprinting of Cannabis sativa L., cannabinoids and terpenoids for chemotaxonomic and drug standardization purposes
    • Fischedick, J.T., Hazekamp, A., Erkelens, T., Choi, Y.H., Verpoorte, R., Metabolic fingerprinting of Cannabis sativa L., cannabinoids and terpenoids for chemotaxonomic and drug standardization purposes. Phytochemistry 71 (2010), 2058–2073, 10.1016/j.phytochem.2010.10.001.
    • (2010) Phytochemistry , vol.71 , pp. 2058-2073
    • Fischedick, J.T.1    Hazekamp, A.2    Erkelens, T.3    Choi, Y.H.4    Verpoorte, R.5
  • 3
    • 41549119875 scopus 로고    scopus 로고
    • Determination of plasma and urine levels of Δ9-tetrahydrocannabinol and its main metabolite by liquid chromatography after solid-phase extraction
    • Mercolini, L., Musenga, A., Comin, I., Baccini, C., Conti, M., Raggi, M.A., Determination of plasma and urine levels of Δ9-tetrahydrocannabinol and its main metabolite by liquid chromatography after solid-phase extraction. J. Pharm. Biomed. Anal. 47 (2008), 156–163, 10.1016/j.jpba.2007.12.023.
    • (2008) J. Pharm. Biomed. Anal. , vol.47 , pp. 156-163
    • Mercolini, L.1    Musenga, A.2    Comin, I.3    Baccini, C.4    Conti, M.5    Raggi, M.A.6
  • 4
    • 84938537472 scopus 로고    scopus 로고
    • Determination of the relative percentage distribution of THCA and Δ(9)-THC in herbal cannabis seized in Austria − Impact of different storage temperatures on stability
    • Taschwer, M., Schmid, M.G., Determination of the relative percentage distribution of THCA and Δ(9)-THC in herbal cannabis seized in Austria − Impact of different storage temperatures on stability. Forensic Sci. Int. 254 (2015), 167–171, 10.1016/j.forsciint.2015.07.019.
    • (2015) Forensic Sci. Int. , vol.254 , pp. 167-171
    • Taschwer, M.1    Schmid, M.G.2
  • 5
    • 84925487676 scopus 로고    scopus 로고
    • Identification and quantification of cannabinoids in Cannabis sativa L. plants by high performance liquid chromatography-mass spectrometry
    • Aizpurua-Olaizola, O., Omar, J., Navarro, P., Olivares, M., Etxebarria, N., Usobiaga, A., Identification and quantification of cannabinoids in Cannabis sativa L. plants by high performance liquid chromatography-mass spectrometry. Anal. Bioanal. Chem. 406 (2014), 7549–7560, 10.1007/s00216-014-8177-x.
    • (2014) Anal. Bioanal. Chem. , vol.406 , pp. 7549-7560
    • Aizpurua-Olaizola, O.1    Omar, J.2    Navarro, P.3    Olivares, M.4    Etxebarria, N.5    Usobiaga, A.6
  • 6
    • 84945312479 scopus 로고    scopus 로고
    • Seized cannabis seeds cultivated in greenhouse: a chemical study by gas chromatography-mass spectrometry and chemometric analysis
    • Mariotti, K. de C., Marcelo, M.C.A., Ortiz, R.S., Borille, B.T., dos Reis, M., Fett, M.S., Ferr??o, M.F., Limberger, R.P., Seized cannabis seeds cultivated in greenhouse: a chemical study by gas chromatography-mass spectrometry and chemometric analysis. Sci. Justice 56 (2016), 35–41, 10.1016/j.scijus.2015.09.002.
    • (2016) Sci. Justice , vol.56 , pp. 35-41
    • Mariotti, K.D.C.1    Marcelo, M.C.A.2    Ortiz, R.S.3    Borille, B.T.4    dos Reis, M.5    Fett, M.S.6    Ferr??o, M.F.7    Limberger, R.P.8
  • 7
    • 84902171176 scopus 로고    scopus 로고
    • Systematic review: efficacy and safety of medical marijuana in selected neurologic disorders: report of the Guideline Development Subcommittee of the American Academy of Neurology
    • Koppel, B.S., Brust, J.C.M., Fife, T., Bronstein, J., Youssof, S., Gronseth, G., Gloss, D., Systematic review: efficacy and safety of medical marijuana in selected neurologic disorders: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology 82 (2014), 1556–1563, 10.1212/WNL.0000000000000363.
    • (2014) Neurology , vol.82 , pp. 1556-1563
    • Koppel, B.S.1    Brust, J.C.M.2    Fife, T.3    Bronstein, J.4    Youssof, S.5    Gronseth, G.6    Gloss, D.7
  • 8
    • 84875408832 scopus 로고    scopus 로고
    • The pharmacologic and clinical effects of medical cannabis
    • Borgelt, L.M., Franson, K.L., Nussbaum, A.M., Wang, G.S., The pharmacologic and clinical effects of medical cannabis. Pharmacotherapy 33 (2013), 195–209, 10.1002/phar.1187.
    • (2013) Pharmacotherapy , vol.33 , pp. 195-209
    • Borgelt, L.M.1    Franson, K.L.2    Nussbaum, A.M.3    Wang, G.S.4
  • 9
    • 29844435136 scopus 로고    scopus 로고
    • Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
    • Blake, D.R., Robson, P., Ho, M., Jubb, R.W., McCabe, C.S., Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology 45 (2006), 50–52, 10.1093/rheumatology/kei183.
    • (2006) Rheumatology , vol.45 , pp. 50-52
    • Blake, D.R.1    Robson, P.2    Ho, M.3    Jubb, R.W.4    McCabe, C.S.5
  • 11
    • 84931560365 scopus 로고    scopus 로고
    • Comprehensive review of medicinal marijuana, cannabinoids, and therapeutic implications in medicine and headache: what a long strange trip it's been
    • Baron, E.P., Comprehensive review of medicinal marijuana, cannabinoids, and therapeutic implications in medicine and headache: what a long strange trip it's been. Headache, 2000, 885–916.
    • (2000) Headache , pp. 885-916
    • Baron, E.P.1
  • 12
    • 33947489961 scopus 로고
    • Isolation, structure, and partial synthesis of an active constituent of hashish
    • Gaoni, Y., Mechoulam, R., Isolation, structure, and partial synthesis of an active constituent of hashish. J. Am. Chem. Soc. 86 (1964), 1646–1647, 10.1021/ja01062a046.
    • (1964) J. Am. Chem. Soc. , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 13
    • 34548523508 scopus 로고    scopus 로고
    • History of cannabis and its preparations in saga, science, and sobriquet
    • Russo, E.B., History of cannabis and its preparations in saga, science, and sobriquet. Chem. Biodivers. 4 (2007), 1614–1648, 10.1002/cbdv.200790144.
    • (2007) Chem. Biodivers. , vol.4 , pp. 1614-1648
    • Russo, E.B.1
  • 14
    • 41549121013 scopus 로고    scopus 로고
    • Cannabinoids in the management of difficult to treat pain
    • Russo, E.B., Cannabinoids in the management of difficult to treat pain. Ther. Clin. Risk Manag. 4 (2008), 245–259.
    • (2008) Ther. Clin. Risk Manag. , vol.4 , pp. 245-259
    • Russo, E.B.1
  • 15
    • 79960306559 scopus 로고    scopus 로고
    • Potential cannabis synergy and phytocannabinoid-terpenoid entourage effects
    • Russo, E.B., Taming, T.H.C., Potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br. J. Pharmacol. 163 (2011), 1344–1364, 10.1111/bph.2011.163.
    • (2011) Br. J. Pharmacol. , vol.163 , pp. 1344-1364
    • Russo, E.B.1    Taming, T.H.C.2
  • 16
    • 84900812931 scopus 로고    scopus 로고
    • Das therapeutische potenzial von cannabis und cannabinoiden
    • Grotenhermen, F., Müller-Vahl, K., Das therapeutische potenzial von cannabis und cannabinoiden. Dtsch. Arztebl. Int. 109 (2012), 495–501, 10.3238/arztebl.2012.0495.
    • (2012) Dtsch. Arztebl. Int. , vol.109 , pp. 495-501
    • Grotenhermen, F.1    Müller-Vahl, K.2
  • 17
    • 0014111318 scopus 로고
    • Tetrahydrocannabinolic acid, a genuine substance of tetrahydrocannabinol
    • Yamauchi, I.N.T., Shoyama, Y., Aramaki, H., Azuma, T., Tetrahydrocannabinolic acid, a genuine substance of tetrahydrocannabinol. Chem. Pharm. Bull. 15 (1967), 1075–1076.
    • (1967) Chem. Pharm. Bull. , vol.15 , pp. 1075-1076
    • Yamauchi, I.N.T.1    Shoyama, Y.2    Aramaki, H.3    Azuma, T.4
  • 18
    • 0022885592 scopus 로고
    • Structure-activity relationships of the cannabinoids
    • RK, R., Structure-activity relationships of the cannabinoids. Pharmacol. Rev. 38 (1986), 75–149.
    • (1986) Pharmacol. Rev. , vol.38 , pp. 75-149
    • RK, R.1
  • 19
    • 0032973507 scopus 로고    scopus 로고
    • The cannabinoid acids: nonpsychoactive derivatives with therapeutic potential
    • Burstein, S.H., The cannabinoid acids: nonpsychoactive derivatives with therapeutic potential. Pharmacol. Ther. 82 (1999), 87–96.
    • (1999) Pharmacol. Ther. , vol.82 , pp. 87-96
    • Burstein, S.H.1
  • 21
    • 85071447718 scopus 로고    scopus 로고
    • Cannabis and cannabis extracts greater than the sum of their parts?, cannabis ther
    • McPartland, J.M., Russo, E.B., Cannabis and cannabis extracts greater than the sum of their parts?, cannabis ther. HIV/AIDS 1 (2001), 103–132, 10.1300/J175v01n03_08.
    • (2001) HIV/AIDS , vol.1 , pp. 103-132
    • McPartland, J.M.1    Russo, E.B.2
  • 22
    • 57149123407 scopus 로고    scopus 로고
    • Chemistry and analysis of phytocannabinoids and other cannabis constituents, forensic sci
    • Brenneisen, R., Chemistry and analysis of phytocannabinoids and other cannabis constituents, forensic sci. Med. Marijuana Cannabinoids, 2007, 17–49, 10.1007/978-1-59259-947-9_2.
    • (2007) Med. Marijuana Cannabinoids , pp. 17-49
    • Brenneisen, R.1
  • 23
    • 84971395052 scopus 로고    scopus 로고
    • Cannabis is more than simply delta(9)-tetrahydrocannabinol
    • (431-432-434)
    • Russo, E.B., McPartland, J.M., Cannabis is more than simply delta(9)-tetrahydrocannabinol. Psychopharmacology (Berl)., 165, 2003, 10.1007/s00213-002-1348-z (431-432-434).
    • (2003) Psychopharmacology (Berl). , vol.165
    • Russo, E.B.1    McPartland, J.M.2
  • 24
    • 1842687083 scopus 로고    scopus 로고
    • Methods for the analysis of cannabinoids in biological materials: a review
    • Raharjo, T.J., Verpoorte, R., Methods for the analysis of cannabinoids in biological materials: a review. Phytochem. Anal. 15 (2004), 79–94, 10.1002/pca.753.
    • (2004) Phytochem. Anal. , vol.15 , pp. 79-94
    • Raharjo, T.J.1    Verpoorte, R.2
  • 25
    • 84892453118 scopus 로고    scopus 로고
    • Analytical approaches for the determination of phytocannabinoids and endocannabinoids in human matrices
    • Battista, N., Sergi, M., Montesano, C., Napoletano, S., Compagnone, D., Maccarrone, M., Analytical approaches for the determination of phytocannabinoids and endocannabinoids in human matrices. Drug Test Anal. 6 (2014), 7–16, 10.1002/dta.1574.
    • (2014) Drug Test Anal. , vol.6 , pp. 7-16
    • Battista, N.1    Sergi, M.2    Montesano, C.3    Napoletano, S.4    Compagnone, D.5    Maccarrone, M.6
  • 26
    • 73249119750 scopus 로고    scopus 로고
    • A qualitative and quantitative HPTLC densitometry method for the analysis of cannabinoids in Cannabis sativa L
    • Fischedick, J.T., Glas, R., Hazekamp, A., Verpoorte, R., A qualitative and quantitative HPTLC densitometry method for the analysis of cannabinoids in Cannabis sativa L. Phytochem. Anal. 20 (2009), 421–426, 10.1002/pca.1143.
    • (2009) Phytochem. Anal. , vol.20 , pp. 421-426
    • Fischedick, J.T.1    Glas, R.2    Hazekamp, A.3    Verpoorte, R.4
  • 27
    • 84949797704 scopus 로고    scopus 로고
    • Development and validation of a reliable and robust method for the analysis of cannabinoids and terpenes in cannabis
    • Giese, M.W., Lewis, M.A., Giese, L., Smith, K.M., Development and validation of a reliable and robust method for the analysis of cannabinoids and terpenes in cannabis. J. AOAC Int. 98 (2015), 1503–1522, 10.5740/jaoacint.15-116.
    • (2015) J. AOAC Int. , vol.98 , pp. 1503-1522
    • Giese, M.W.1    Lewis, M.A.2    Giese, L.3    Smith, K.M.4
  • 28
    • 85032349407 scopus 로고    scopus 로고
    • F. Institute, for D. and M. (BfArM) Devices German Cannabis Monograph Draft_EN
    • F. Institute, for D. and M. (BfArM) Devices German Cannabis Monograph Draft_EN. 2016, 1–9.
    • (2016) , pp. 1-9
  • 29
    • 84931572672 scopus 로고    scopus 로고
    • Screening of cannabinoids in industrial-grade hemp using two-dimensional liquid chromatography coupled with acidic potassium permanganate chemiluminescence detection
    • Pandohee, J., Holland, B.J., Li, B., Tsuzuki, T., Stevenson, P.G., Barnett, N.W., Pearson, J.R., Jones, O.A.H., Conlan, X.A., Screening of cannabinoids in industrial-grade hemp using two-dimensional liquid chromatography coupled with acidic potassium permanganate chemiluminescence detection. J. Sep. Sci. 38 (2015), 2024–2032, 10.1002/jssc.201500088.
    • (2015) J. Sep. Sci. , vol.38 , pp. 2024-2032
    • Pandohee, J.1    Holland, B.J.2    Li, B.3    Tsuzuki, T.4    Stevenson, P.G.5    Barnett, N.W.6    Pearson, J.R.7    Jones, O.A.H.8    Conlan, X.A.9
  • 30
    • 3343009510 scopus 로고    scopus 로고
    • A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae)
    • Hillig, K.W., Mahlberg, P.G., A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae). Am. J. Bot. 91 (2004), 966–975, 10.3732/ajb.91.6.966.
    • (2004) Am. J. Bot. , vol.91 , pp. 966-975
    • Hillig, K.W.1    Mahlberg, P.G.2
  • 32
    • 84938400452 scopus 로고    scopus 로고
    • Transformations of Tetrahydrocannabinol, tetrahydrocannabinolic acid and cannabinol during their extraction from Cannabis sativa L
    • Wianowska, D., Dawidowicz, A.L., Kowalczyk, M., Transformations of Tetrahydrocannabinol, tetrahydrocannabinolic acid and cannabinol during their extraction from Cannabis sativa L. J. Anal. Chem. 70 (2015), 920–925, 10.1134/S1061934815080183.
    • (2015) J. Anal. Chem. , vol.70 , pp. 920-925
    • Wianowska, D.1    Dawidowicz, A.L.2    Kowalczyk, M.3
  • 33
    • 11144341467 scopus 로고    scopus 로고
    • A rapid and simple procedure for the determination of cannabinoids in hemp food products by gas chromatography-mass spectrometry
    • Pellegrini, M., Marchei, E., Pacifici, R., Pichini, S., A rapid and simple procedure for the determination of cannabinoids in hemp food products by gas chromatography-mass spectrometry. J. Pharm. Biomed. Anal. 36 (2005), 939–946, 10.1016/j.jpba.2004.07.035.
    • (2005) J. Pharm. Biomed. Anal. , vol.36 , pp. 939-946
    • Pellegrini, M.1    Marchei, E.2    Pacifici, R.3    Pichini, S.4
  • 34
    • 84926500681 scopus 로고    scopus 로고
    • 1H NMR and HPLC/DAD for Cannabis sativa L. chemotype distinction, extract profiling and specification
    • Peschel, W., Politi, M., 1H NMR and HPLC/DAD for Cannabis sativa L. chemotype distinction, extract profiling and specification. Talanta 140 (2015), 150–165, 10.1016/j.talanta.2015.02.040.
    • (2015) Talanta , vol.140 , pp. 150-165
    • Peschel, W.1    Politi, M.2
  • 35
    • 37549002467 scopus 로고    scopus 로고
    • Direct NMR analysis of cannabis water extracts and tinctures and semi-quantitative data on D 9 −THC and D 9 −THC-acid
    • Politi, M., Peschel, W., Wilson, N., Zloh, M., Prieto, J.M., Heinrich, M., Direct NMR analysis of cannabis water extracts and tinctures and semi-quantitative data on D 9 −THC and D 9 −THC-acid. Phytochemistry 69 (2008), 562–570, 10.1016/j.phytochem.2007.07.018.
    • (2008) Phytochemistry , vol.69 , pp. 562-570
    • Politi, M.1    Peschel, W.2    Wilson, N.3    Zloh, M.4    Prieto, J.M.5    Heinrich, M.6
  • 36
    • 84876124013 scopus 로고    scopus 로고
    • Cloud point extraction of Δ9-tetrahydrocannabinol from cannabis resin
    • Ameur, S., Haddou, B., Derriche, Z., Canselier, J.P., Gourdon, C., Cloud point extraction of Δ9-tetrahydrocannabinol from cannabis resin. Anal. Bioanal. Chem. 405 (2013), 3117–3123, 10.1007/s00216-013-6743-2.
    • (2013) Anal. Bioanal. Chem. , vol.405 , pp. 3117-3123
    • Ameur, S.1    Haddou, B.2    Derriche, Z.3    Canselier, J.P.4    Gourdon, C.5
  • 37
    • 84876293061 scopus 로고    scopus 로고
    • Optimisation and characterisation of marihuana extracts obtained by supercritical fluid extraction and focused ultrasound extraction and retention time locking GC–MS
    • Omar, J., Olivares, M., Alzaga, M., Etxebarria, N., Optimisation and characterisation of marihuana extracts obtained by supercritical fluid extraction and focused ultrasound extraction and retention time locking GC–MS. J. Sep. Sci. 36 (2013), 1397–1404, 10.1002/jssc.201201103.
    • (2013) J. Sep. Sci. , vol.36 , pp. 1397-1404
    • Omar, J.1    Olivares, M.2    Alzaga, M.3    Etxebarria, N.4
  • 38
    • 34447562769 scopus 로고    scopus 로고
    • Cannabis tea revisited: a systematic evaluation of the cannabinoid composition of cannabis tea
    • Hazekamp, A., Bastola, K., Rashidi, H., Bender, J., Verpoorte, R., Cannabis tea revisited: a systematic evaluation of the cannabinoid composition of cannabis tea. J. Ethnopharmacol. 113 (2007), 85–90, 10.1016/j.jep.2007.05.019.
    • (2007) J. Ethnopharmacol. , vol.113 , pp. 85-90
    • Hazekamp, A.1    Bastola, K.2    Rashidi, H.3    Bender, J.4    Verpoorte, R.5
  • 39
    • 85028512265 scopus 로고    scopus 로고
    • Evaluation of cannabinoids concentration and stability in standardized preparations of cannabis tea and cannabis oil by ultra-high performance liquid chromatography tandem mass spectrometry
    • Pacifici, R., Marchei, E., Salvatore, F., Guandalini, L., Busardò, F.P., Pichini, S., Evaluation of cannabinoids concentration and stability in standardized preparations of cannabis tea and cannabis oil by ultra-high performance liquid chromatography tandem mass spectrometry. Clin. Chem. Lab. Med. 0 (2017), 1–9, 10.1515/cclm-2016-1060.
    • (2017) Clin. Chem. Lab. Med. , pp. 1-9
    • Pacifici, R.1    Marchei, E.2    Salvatore, F.3    Guandalini, L.4    Busardò, F.P.5    Pichini, S.6
  • 40
    • 84925640008 scopus 로고    scopus 로고
    • Cannabis Oil: chemical evaluation of an upcoming cannabis-based medicine
    • Romano, L.L., Hazekamp, A., Cannabis Oil: chemical evaluation of an upcoming cannabis-based medicine. Cannabinoids 1 (2013), 1–11, 10.1002/dta.407.
    • (2013) Cannabinoids , vol.1 , pp. 1-11
    • Romano, L.L.1    Hazekamp, A.2
  • 41
    • 84971441343 scopus 로고    scopus 로고
    • Medicinal Cannabis: principal cannabinoids concentration and their stability evaluated by a high performance liquid chromatography coupled to diode array and quadrupole time of flight mass spectrometry method
    • Citti, C., Ciccarella, G., Braghiroli, D., Parenti, C., M.A.M.A, Vandelli, Cannazza, G., Medicinal Cannabis: principal cannabinoids concentration and their stability evaluated by a high performance liquid chromatography coupled to diode array and quadrupole time of flight mass spectrometry method. J. Pharm. Biomed. Anal. 128 (2016), 201–209, 10.1016/j.jpba.2016.05.033.
    • (2016) J. Pharm. Biomed. Anal. , vol.128 , pp. 201-209
    • Citti, C.1    Ciccarella, G.2    Braghiroli, D.3    Parenti, C.4    M.A.M.A, V.5    Cannazza, G.6
  • 42
    • 84857646969 scopus 로고    scopus 로고
    • Cannabinoids and metabolites in expectorated oral fluid following controlled smoked cannabis
    • Milman, G., Schwope, D.M., Gorelick, D.A., Huestis, M.A., Cannabinoids and metabolites in expectorated oral fluid following controlled smoked cannabis. Clin. Chim. Acta. 413 (2012), 765–770, 10.1016/j.cca.2012.01.011.
    • (2012) Clin. Chim. Acta. , vol.413 , pp. 765-770
    • Milman, G.1    Schwope, D.M.2    Gorelick, D.A.3    Huestis, M.A.4
  • 44
    • 84938771606 scopus 로고    scopus 로고
    • Quantification of six cannabinoids and metabolites in oral fluid by liquid chromatography-tandem mass spectrometry
    • Desrosiers, N.A., Scheidweiler, K.B., Huestis, M.A., Quantification of six cannabinoids and metabolites in oral fluid by liquid chromatography-tandem mass spectrometry. Drug Test Anal. 7 (2015), 684–694, 10.1002/dta.1753.
    • (2015) Drug Test Anal. , vol.7 , pp. 684-694
    • Desrosiers, N.A.1    Scheidweiler, K.B.2    Huestis, M.A.3
  • 45
    • 75349105129 scopus 로고    scopus 로고
    • Simultaneous quantification of cannabinoids and metabolites in oral fluid by two-dimensional gas chromatography mass spectrometry
    • Milman, G., Barnes, A.J., Lowe, R.H., Huestis, M.A., Simultaneous quantification of cannabinoids and metabolites in oral fluid by two-dimensional gas chromatography mass spectrometry. J. Chromatogr. A 1217 (2010), 1513–1521, 10.1016/j.chroma.2009.12.053.
    • (2010) J. Chromatogr. A , vol.1217 , pp. 1513-1521
    • Milman, G.1    Barnes, A.J.2    Lowe, R.H.3    Huestis, M.A.4
  • 46
    • 85032387751 scopus 로고    scopus 로고
    • Simultaneous Quantification of Δ9-Tetrahydrocannabinol, 11-nor-9-carboxy-Tetrahydrocannabinol, Cannabidiol and Cannabinol in Oral Fluid by MicroFlow-Liquid Chromatography- High Resolution Mass Spectrometry
    • Concheiro, M., Lee, D., Lendoiro, E., Huestis, M.A., Simultaneous Quantification of Δ9-Tetrahydrocannabinol, 11-nor-9-carboxy-Tetrahydrocannabinol, Cannabidiol and Cannabinol in Oral Fluid by MicroFlow-Liquid Chromatography- High Resolution Mass Spectrometry. J. Chromatogr. A 454 (2007), 42–54, 10.1097/OPX.0b013e3182540562.
    • (2007) J. Chromatogr. A , vol.454 , pp. 42-54
    • Concheiro, M.1    Lee, D.2    Lendoiro, E.3    Huestis, M.A.4
  • 47
    • 84879880664 scopus 로고    scopus 로고
    • Micro extraction by packed sorbent coupled to liquid chromatography tandem mass spectrometry for the rapid and sensitive determination of cannabinoids in oral fluids
    • Sergi, M., Montesano, C., Odoardi, S., Mainero Rocca, L., Fabrizi, G., Compagnone, D., Curini, R., Micro extraction by packed sorbent coupled to liquid chromatography tandem mass spectrometry for the rapid and sensitive determination of cannabinoids in oral fluids. J. Chromatogr. A 1301 (2013), 139–146, 10.1016/j.chroma.2013.05.072.
    • (2013) J. Chromatogr. A , vol.1301 , pp. 139-146
    • Sergi, M.1    Montesano, C.2    Odoardi, S.3    Mainero Rocca, L.4    Fabrizi, G.5    Compagnone, D.6    Curini, R.7
  • 48
    • 34547297201 scopus 로고    scopus 로고
    • Bioanalytical procedures for determination of drugs of abuse in oral fluid
    • Samyn, N., Laloup, M., De Boeck, G., Bioanalytical procedures for determination of drugs of abuse in oral fluid. Anal. Bioanal. Chem. 388 (2007), 1437–1453, 10.1007/s00216-007-1245-8.
    • (2007) Anal. Bioanal. Chem. , vol.388 , pp. 1437-1453
    • Samyn, N.1    Laloup, M.2    De Boeck, G.3
  • 49
    • 84865714959 scopus 로고    scopus 로고
    • Fast liquid chromatography/tandem mass spectrometry determination of cannabinoids in micro volume blood samples after dabsyl derivatization
    • Lacroix, C., Saussereau, E., Fast liquid chromatography/tandem mass spectrometry determination of cannabinoids in micro volume blood samples after dabsyl derivatization. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 905 (2012), 85–95, 10.1016/j.jchromb.2012.08.006.
    • (2012) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.905 , pp. 85-95
    • Lacroix, C.1    Saussereau, E.2
  • 50
    • 80052559344 scopus 로고    scopus 로고
    • Direct quantification of cannabinoids and cannabinoid glucuronides in whole blood by liquid chromatography-tandem mass spectrometry
    • Schwope, D.M., Scheidweiler, K.B., Huestis, M.A., Direct quantification of cannabinoids and cannabinoid glucuronides in whole blood by liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem. 401 (2011), 1273–1283, 10.1007/s00216-011-5197-7.
    • (2011) Anal. Bioanal. Chem. , vol.401 , pp. 1273-1283
    • Schwope, D.M.1    Scheidweiler, K.B.2    Huestis, M.A.3
  • 51
    • 79954431386 scopus 로고    scopus 로고
    • On-line SPE LC-MS/MS for the quantification of Δ9-tetrahydrocannabinol (THC) and its two major metabolites in human peripheral blood by liquid chromatography tandem mass spectrometry
    • König, S., Aebi, B., Lanz, S., Gasser, M., Weinmann, W., On-line SPE LC-MS/MS for the quantification of Δ9-tetrahydrocannabinol (THC) and its two major metabolites in human peripheral blood by liquid chromatography tandem mass spectrometry. Anal. Bioanal. Chem. 400 (2011), 9–16, 10.1007/s00216-011-4708-x.
    • (2011) Anal. Bioanal. Chem. , vol.400 , pp. 9-16
    • König, S.1    Aebi, B.2    Lanz, S.3    Gasser, M.4    Weinmann, W.5
  • 52
    • 79959567447 scopus 로고    scopus 로고
    • A preliminary investigation on the distribution of cannabinoids in man
    • Gronewold, A., Skopp, G., A preliminary investigation on the distribution of cannabinoids in man. Forensic Sci. Int. 210 (2011), e7–e11, 10.1016/j.forsciint.2011.04.010.
    • (2011) Forensic Sci. Int. , vol.210 , pp. e7-e11
    • Gronewold, A.1    Skopp, G.2
  • 53
    • 84920608538 scopus 로고    scopus 로고
    • Recent trends in analytical methods and separation techniques for drugs of abuse in hair
    • Baciu, T., Borrull, F., Aguilar, C., Calull, M., Recent trends in analytical methods and separation techniques for drugs of abuse in hair. Anal. Chim. Acta 856 (2015), 1–26, 10.1016/j.aca.2014.06.051.
    • (2015) Anal. Chim. Acta , vol.856 , pp. 1-26
    • Baciu, T.1    Borrull, F.2    Aguilar, C.3    Calull, M.4
  • 54
    • 69249151211 scopus 로고    scopus 로고
    • A semi-automated solid-phase extraction liquid chromatography/tandem mass spectrometry method for the analysis of tetrahydrocannabinol and metabolites in whole blood
    • Jagerdeo, E., Schaff, J.E., Montgomery, M.A., LeBeau, M.A., A semi-automated solid-phase extraction liquid chromatography/tandem mass spectrometry method for the analysis of tetrahydrocannabinol and metabolites in whole blood. Rapid Commun. Mass Spectrom. 23 (2009), 2697–2705.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , pp. 2697-2705
    • Jagerdeo, E.1    Schaff, J.E.2    Montgomery, M.A.3    LeBeau, M.A.4
  • 55
    • 70350499852 scopus 로고    scopus 로고
    • Solid-phase extraction and analysis of THC and carboxy-THC from whole blood using a novel fluorinated solid-phase extraction sorbent and fast liquid chromatography-tandem mass spectrometry
    • Elian, A.A., Hackett, J., Solid-phase extraction and analysis of THC and carboxy-THC from whole blood using a novel fluorinated solid-phase extraction sorbent and fast liquid chromatography-tandem mass spectrometry. J. Anal. Toxicol. 33 (2009), 461–468, 10.1093/jat/33.8.461.
    • (2009) J. Anal. Toxicol. , vol.33 , pp. 461-468
    • Elian, A.A.1    Hackett, J.2
  • 57
    • 77953808569 scopus 로고    scopus 로고
    • Validation of an analytical method for analysis of cannabinoids in hair by headspace solid-phase microextraction and gas chromatography-ion trap tandem mass spectrometry
    • Emídio, E.S., de Menezes Prata, V., Dórea, H.S., Validation of an analytical method for analysis of cannabinoids in hair by headspace solid-phase microextraction and gas chromatography-ion trap tandem mass spectrometry. Anal. Chim. Acta. 670 (2010), 63–71, 10.1016/j.aca.2010.04.023.
    • (2010) Anal. Chim. Acta. , vol.670 , pp. 63-71
    • Emídio, E.S.1    de Menezes Prata, V.2    Dórea, H.S.3
  • 58
    • 33846425383 scopus 로고    scopus 로고
    • Simple and sensitive determination of??9-tetrahydrocannabinol, cannabidiol and cannabinol in hair by combined silylation, headspace solid phase microextraction and gas chromatography-mass spectrometry
    • Nadulski, T., Pragst, F., Simple and sensitive determination of??9-tetrahydrocannabinol, cannabidiol and cannabinol in hair by combined silylation, headspace solid phase microextraction and gas chromatography-mass spectrometry. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 846 (2007), 78–85, 10.1016/j.jchromb.2006.08.015.
    • (2007) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.846 , pp. 78-85
    • Nadulski, T.1    Pragst, F.2
  • 59
    • 84965167376 scopus 로고    scopus 로고
    • GCMS analysis of Cannabis sativa L. from four different areas of Pakistan
    • Tayyab, M., Shahwar, D., GCMS analysis of Cannabis sativa L. from four different areas of Pakistan. Egypt. J. Forensic Sci. 5 (2015), 114–125, 10.1016/j.ejfs.2014.07.008.
    • (2015) Egypt. J. Forensic Sci. , vol.5 , pp. 114-125
    • Tayyab, M.1    Shahwar, D.2
  • 60
    • 77952291222 scopus 로고    scopus 로고
    • Chemical analysis of synthetic cannabinoids as designer drugs in herbal products
    • Uchiyama, N., Kikura-Hanajiri, R., Ogata, J., Goda, Y., Chemical analysis of synthetic cannabinoids as designer drugs in herbal products. Forensic Sci. Int. 198 (2010), 31–38, 10.1016/j.forsciint.2010.01.004.
    • (2010) Forensic Sci. Int. , vol.198 , pp. 31-38
    • Uchiyama, N.1    Kikura-Hanajiri, R.2    Ogata, J.3    Goda, Y.4
  • 61
    • 25444479118 scopus 로고    scopus 로고
    • Chromatographic and spectroscopic data of cannabinoids from cannabis sativa l
    • Hazekamp, A., Peltenburg, A., Verpoorte, R., Giroud, C., Chromatographic and spectroscopic data of cannabinoids from cannabis sativa l. J. Liq. Chromatogr. Relat. Technol. 28 (2005), 2361–2382, 10.1080/10826070500187558.
    • (2005) J. Liq. Chromatogr. Relat. Technol. , vol.28 , pp. 2361-2382
    • Hazekamp, A.1    Peltenburg, A.2    Verpoorte, R.3    Giroud, C.4
  • 62
    • 14244249773 scopus 로고    scopus 로고
    • Isolation of Δ9-THCA-A from hemp and analytical aspects concerning the determination of Δ9-THC in cannabis products
    • Dussy, F.E., Hamberg, C., Luginbühl, M., Schwerzmann, T., Briellmann, T.A., Isolation of Δ9-THCA-A from hemp and analytical aspects concerning the determination of Δ9-THC in cannabis products. Forensic Sci. Int. 149 (2005), 3–10, 10.1016/j.forsciint.2004.05.015.
    • (2005) Forensic Sci. Int. , vol.149 , pp. 3-10
    • Dussy, F.E.1    Hamberg, C.2    Luginbühl, M.3    Schwerzmann, T.4    Briellmann, T.A.5
  • 63
    • 0037130917 scopus 로고    scopus 로고
    • Determination of primary active constituents in Cannabis preparations by high-resolution gas chromatography/flame ionization detection and high-performance liquid chromatography/UV detection
    • Gambaro, V., Dell'Acqua, L., Farè, F., Froldi, R., Saligari, E., Tassoni, G., Determination of primary active constituents in Cannabis preparations by high-resolution gas chromatography/flame ionization detection and high-performance liquid chromatography/UV detection. Anal. Chim. Acta. 468 (2002), 245–254, 10.1016/S0003-2670(02)00660-8.
    • (2002) Anal. Chim. Acta. , vol.468 , pp. 245-254
    • Gambaro, V.1    Dell'Acqua, L.2    Farè, F.3    Froldi, R.4    Saligari, E.5    Tassoni, G.6
  • 64
    • 29144518601 scopus 로고    scopus 로고
    • Simultaneous and sensitive analysis of THC, 11-OH-THC, THC-COOH, CBD, and CBN by GC–MS in plasma after oral application of small doses of THC and cannabis extract
    • P.F. Nadulski, T., Sporkert, F., Schnelle, M., Stadelmann, A.M., Roser, P., Schefter, T., Simultaneous and sensitive analysis of THC, 11-OH-THC, THC-COOH, CBD, and CBN by GC–MS in plasma after oral application of small doses of THC and cannabis extract. J. Anal.Toxicol. 29 (2005), 782–789.
    • (2005) J. Anal.Toxicol. , vol.29 , pp. 782-789
    • P.F. Nadulski, T.1    Sporkert, F.2    Schnelle, M.3    Stadelmann, A.M.4    Roser, P.5    Schefter, T.6
  • 65
    • 27744458487 scopus 로고    scopus 로고
    • Simultaneous analysis of the Delta9-THC metabolites 11-nor-9-carboxy-Delta9-THC and 11-hydroxy-Delta9-THC in meconium by GC–MS
    • U.F. Coles, R., Clements, T.T., Nelson, G.J., McMillin, G.A., Simultaneous analysis of the Delta9-THC metabolites 11-nor-9-carboxy-Delta9-THC and 11-hydroxy-Delta9-THC in meconium by GC–MS. J. Anal.Toxicol. 29 (2005), 522–527.
    • (2005) J. Anal.Toxicol. , vol.29 , pp. 522-527
    • U.F. Coles, R.1    Clements, T.T.2    Nelson, G.J.3    McMillin, G.A.4
  • 66
    • 85153983614 scopus 로고    scopus 로고
    • Determination of 11-nor-D9-tetrahydrocannabinol-9-carboxylic acid in hair using gas chromatography/tandem mass spectrometry in negative ion chemical ionization mode
    • Moore, C., Guzaldo, F., Donahue, T., Determination of 11-nor-D9-tetrahydrocannabinol-9-carboxylic acid in hair using gas chromatography/tandem mass spectrometry in negative ion chemical ionization mode. Rapid Commun. Mass Spectrom. 21 (2007), 1339–1342, 10.1002/rcm.
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , pp. 1339-1342
    • Moore, C.1    Guzaldo, F.2    Donahue, T.3
  • 67
    • 35348838320 scopus 로고    scopus 로고
    • Fast gas chromatography and negative-ion chemical ionization tandem mass spectrometry for forensic analysis of cannabinoids in whole blood
    • Thomas, A., Widmer, C., Hopfgartner, G., Staub, C., Fast gas chromatography and negative-ion chemical ionization tandem mass spectrometry for forensic analysis of cannabinoids in whole blood. J. Pharm. Biomed. Anal. 45 (2007), 495–503, 10.1016/j.jpba.2007.08.019.
    • (2007) J. Pharm. Biomed. Anal. , vol.45 , pp. 495-503
    • Thomas, A.1    Widmer, C.2    Hopfgartner, G.3    Staub, C.4
  • 68
    • 84865652730 scopus 로고    scopus 로고
    • A validated method for the analysis of cannabinoids in post-mortem blood using liquid-liquid extraction and two-dimensional gas chromatography-mass spectrometry
    • Andrews, R., Paterson, S., A validated method for the analysis of cannabinoids in post-mortem blood using liquid-liquid extraction and two-dimensional gas chromatography-mass spectrometry. Forensic Sci. Int. 222 (2012), 111–117, 10.1016/j.forsciint.2012.05.007.
    • (2012) Forensic Sci. Int. , vol.222 , pp. 111-117
    • Andrews, R.1    Paterson, S.2
  • 69
    • 34547828152 scopus 로고    scopus 로고
    • Simultaneous quantification of Δ9-tetrahydrocannabinol, 11-hydroxy-Δ9-tetrahydrocannabinol, and 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in human plasma using two-dimensional gas chromatography, cryofocusing, and electron impact-mass spectromet
    • Lowe, R.H., Karschner, E.L., Schwilke, E.W., Barnes, A.J., Huestis, M.A., Simultaneous quantification of Δ9-tetrahydrocannabinol, 11-hydroxy-Δ9-tetrahydrocannabinol, and 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in human plasma using two-dimensional gas chromatography, cryofocusing, and electron impact-mass spectromet. J. Chromatogr. A. 1163 (2007), 318–327, 10.1016/j.chroma.2007.06.069.
    • (2007) J. Chromatogr. A. , vol.1163 , pp. 318-327
    • Lowe, R.H.1    Karschner, E.L.2    Schwilke, E.W.3    Barnes, A.J.4    Huestis, M.A.5
  • 70
    • 79952245806 scopus 로고    scopus 로고
    • Simultaneous analysis of frequently used licit and illicit psychoactive drugs in breast milk by liquid chromatography tandem mass spectrometry
    • Marchei, E., Escuder, D., Pallas, C.R., Garcia-Algar, O., Gómez, A., Friguls, B., Pellegrini, M., Pichini, S., Simultaneous analysis of frequently used licit and illicit psychoactive drugs in breast milk by liquid chromatography tandem mass spectrometry. J. Pharm. Biomed. Anal. 55 (2011), 309–316, 10.1016/j.jpba.2011.01.028.
    • (2011) J. Pharm. Biomed. Anal. , vol.55 , pp. 309-316
    • Marchei, E.1    Escuder, D.2    Pallas, C.R.3    Garcia-Algar, O.4    Gómez, A.5    Friguls, B.6    Pellegrini, M.7    Pichini, S.8
  • 71
    • 33947206630 scopus 로고    scopus 로고
    • Detection of D9-tetrahydrocannabinolic acid A in human urine and blood serum by LC–MS/MS
    • Jung, J., Kempf, J., Mahler, H., Weinmann, W., Detection of D9-tetrahydrocannabinolic acid A in human urine and blood serum by LC–MS/MS. J. Mass Spectrom. 42 (2007), 354–360, 10.1002/jms.
    • (2007) J. Mass Spectrom. , vol.42 , pp. 354-360
    • Jung, J.1    Kempf, J.2    Mahler, H.3    Weinmann, W.4
  • 72
    • 2642554857 scopus 로고    scopus 로고
    • Simultaneous determination of Δ9-tetrahydrocannabinol, 11-hydroxy-Δ9-tetrahydrocannabinol and 11 −nor-9-carboxy-Δ9-tetrahydrocannabinol in human plasma by high-performance liquid chromatography/tandem mass spectrometry
    • Maralikova, B., Weinmann, W., Simultaneous determination of Δ9-tetrahydrocannabinol, 11-hydroxy-Δ9-tetrahydrocannabinol and 11 −nor-9-carboxy-Δ9-tetrahydrocannabinol in human plasma by high-performance liquid chromatography/tandem mass spectrometry. J. Mass Spectrom. 39 (2004), 526–531, 10.1002/jms.616.
    • (2004) J. Mass Spectrom. , vol.39 , pp. 526-531
    • Maralikova, B.1    Weinmann, W.2
  • 73
    • 34247276611 scopus 로고    scopus 로고
    • Development of a LC/MS/MS method for the analysis of cannabinoids in human EDTA-plasma and urine after small doses of Cannabis sativa extracts
    • Grauwiler, S.B., Scholer, A., Drewe, J., Development of a LC/MS/MS method for the analysis of cannabinoids in human EDTA-plasma and urine after small doses of Cannabis sativa extracts. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 850 (2007), 515–522, 10.1016/j.jchromb.2006.12.045.
    • (2007) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.850 , pp. 515-522
    • Grauwiler, S.B.1    Scholer, A.2    Drewe, J.3
  • 74
    • 84870298987 scopus 로고    scopus 로고
    • Distribution of free and conjugated cannabinoids in human bile samples
    • Fabritius, M., Staub, C., Mangin, P., Giroud, C., Distribution of free and conjugated cannabinoids in human bile samples. Forensic Sci. Int. 223 (2012), 114–118, 10.1016/j.forsciint.2012.08.013.
    • (2012) Forensic Sci. Int. , vol.223 , pp. 114-118
    • Fabritius, M.1    Staub, C.2    Mangin, P.3    Giroud, C.4
  • 75
    • 34447636907 scopus 로고    scopus 로고
    • Validated method for the simultaneous determination of Δ9-THC and Δ9-THC-COOH in oral fluid, urine and whole blood using solid-phase extraction and liquid chromatography-mass spectrometry with electrospray ionization
    • Teixeira, H., Verstraete, A., Proença, P., Corte-Real, F., Monsanto, P., Vieira, D.N., Validated method for the simultaneous determination of Δ9-THC and Δ9-THC-COOH in oral fluid, urine and whole blood using solid-phase extraction and liquid chromatography-mass spectrometry with electrospray ionization. Forensic Sci. Int. 170 (2007), 148–155, 10.1016/j.forsciint.2007.03.026.
    • (2007) Forensic Sci. Int. , vol.170 , pp. 148-155
    • Teixeira, H.1    Verstraete, A.2    Proença, P.3    Corte-Real, F.4    Monsanto, P.5    Vieira, D.N.6
  • 77
    • 84873391976 scopus 로고    scopus 로고
    • Development and validation of an LC-MS/MS method for quantification of Δ9-tetrahydrocannabinolic acid A (THCA-A), THC, CBN and CBD in hair
    • Roth, N., Moosmann, B., Auwärter, V., Development and validation of an LC-MS/MS method for quantification of Δ9-tetrahydrocannabinolic acid A (THCA-A), THC, CBN and CBD in hair. J. Mass Spectrom. 48 (2013), 227–233, 10.1002/jms.3152.
    • (2013) J. Mass Spectrom. , vol.48 , pp. 227-233
    • Roth, N.1    Moosmann, B.2    Auwärter, V.3
  • 78
    • 84880764533 scopus 로고    scopus 로고
    • Analysis of cannabis seizures in NSW, Australia: cannabis potency and cannabinoid profile
    • Swift, W., Wong, A., Li, K.M., Arnold, J.C., McGregor, I.S., Analysis of cannabis seizures in NSW, Australia: cannabis potency and cannabinoid profile. PLoS One. 8 (2013), 1–9, 10.1371/journal.pone.0070052.
    • (2013) PLoS One. , vol.8 , pp. 1-9
    • Swift, W.1    Wong, A.2    Li, K.M.3    Arnold, J.C.4    McGregor, I.S.5
  • 80
    • 84940960676 scopus 로고    scopus 로고
    • Separation of cannabinoids on three different mixed-mode columns containing carbon/nanodiamond/amine-polymer superficially porous particles
    • Hung, C.H., Zukowski, J., Jensen, D.S., Miles, A.J., Sulak, C., Dadson, A.E., Linford, M.R., Separation of cannabinoids on three different mixed-mode columns containing carbon/nanodiamond/amine-polymer superficially porous particles. J. Sep. Sci. 38 (2015), 2968–2974, 10.1002/jssc.201500156.
    • (2015) J. Sep. Sci. , vol.38 , pp. 2968-2974
    • Hung, C.H.1    Zukowski, J.2    Jensen, D.S.3    Miles, A.J.4    Sulak, C.5    Dadson, A.E.6    Linford, M.R.7
  • 81
    • 84992372769 scopus 로고
    • Analytical and preparative enantioseparation and main chiroptical properties of Iridium(III) bis(4, 6-difluorophenylpyridinato)picolinato
    • Citti, C., Battisti, U.M., Ciccarella, G., Maiorano, V., Gigli, G., Abbate, S., Mazzeo, G., Castiglioni, E., Longhi, G., Cannazza, G., Analytical and preparative enantioseparation and main chiroptical properties of Iridium(III) bis(4, 6-difluorophenylpyridinato)picolinato. J. Chromatogr. A. 2016 (1467), 335–346, 10.1016/j.chroma.2016.05.059.
    • (1467) J. Chromatogr. A. , vol.2016 , pp. 335-346
    • Citti, C.1    Battisti, U.M.2    Ciccarella, G.3    Maiorano, V.4    Gigli, G.5    Abbate, S.6    Mazzeo, G.7    Castiglioni, E.8    Longhi, G.9    Cannazza, G.10
  • 82
    • 78649905224 scopus 로고    scopus 로고
    • Two-dimensional liquid chromatography/mass spectrometry/mass spectrometry separation of water-soluble metabolites
    • Fairchild, J.N., Horvath, K., Gooding, J.R., Campagna, S.R., Guiochon, G., Two-dimensional liquid chromatography/mass spectrometry/mass spectrometry separation of water-soluble metabolites. J. Chromatogr. A 1217 (2010), 8161–8166, 10.1016/j.chroma.2010.10.068.
    • (2010) J. Chromatogr. A , vol.1217 , pp. 8161-8166
    • Fairchild, J.N.1    Horvath, K.2    Gooding, J.R.3    Campagna, S.R.4    Guiochon, G.5
  • 83
    • 85007017304 scopus 로고
    • Metabolite fingerprinting of Punica granatum L. (pomegranate) polyphenols by means of high-performance liquid chromatography with diode array and electrospray ionization-mass spectrometry detection
    • Brighenti, V., Groothuis, S.F., Prencipe, F.P., Amir, R., Benvenuti, S., Pellati, F., Metabolite fingerprinting of Punica granatum L. (pomegranate) polyphenols by means of high-performance liquid chromatography with diode array and electrospray ionization-mass spectrometry detection. J. Chromatogr. A 2017 (1480), 20–31, 10.1016/j.chroma.2016.12.017.
    • (1480) J. Chromatogr. A , vol.2017 , pp. 20-31
    • Brighenti, V.1    Groothuis, S.F.2    Prencipe, F.P.3    Amir, R.4    Benvenuti, S.5    Pellati, F.6
  • 85
    • 77950298443 scopus 로고    scopus 로고
    • Two cases of lysergamide intoxication by ingestion of seeds from Hawaiian Baby Woodrosei
    • Klinke, H.B., Müller, I.B., Steffenrud, S., Dahl-Sørensen, R., Two cases of lysergamide intoxication by ingestion of seeds from Hawaiian Baby Woodrosei. Forensic Sci. Int. 197 (2010), 1–5, 10.1016/j.forsciint.2009.11.017.
    • (2010) Forensic Sci. Int. , vol.197 , pp. 1-5
    • Klinke, H.B.1    Müller, I.B.2    Steffenrud, S.3    Dahl-Sørensen, R.4
  • 86
    • 84862673727 scopus 로고    scopus 로고
    • Prevalence of alcohol and other psychoactive substances in injured drivers: comparison between Belgium and the Netherlands
    • Legrand, S.A., Houwing, S., Hagenzieker, M., Verstraete, A.G., Prevalence of alcohol and other psychoactive substances in injured drivers: comparison between Belgium and the Netherlands. Forensic Sci. Int. 220 (2012), 224–231, 10.1016/j.forsciint.2012.03.006.
    • (2012) Forensic Sci. Int. , vol.220 , pp. 224-231
    • Legrand, S.A.1    Houwing, S.2    Hagenzieker, M.3    Verstraete, A.G.4
  • 87
    • 84941062363 scopus 로고    scopus 로고
    • Application of a validated LC-MS/MS method for JWH-073 and its metabolites in blood and urine in real forensic cases
    • Ozturk, S., Ozturk, Y.E., Yeter, O., Alpertunga, B., Application of a validated LC-MS/MS method for JWH-073 and its metabolites in blood and urine in real forensic cases. Forensic Sci. Int. 257 (2015), 165–171, 10.1016/j.forsciint.2015.08.013.
    • (2015) Forensic Sci. Int. , vol.257 , pp. 165-171
    • Ozturk, S.1    Ozturk, Y.E.2    Yeter, O.3    Alpertunga, B.4
  • 88
    • 84890838359 scopus 로고    scopus 로고
    • Detection of pesticides in seized illegal cannabis plants
    • Schneider, S., Bebing, R., Dauberschmidt, C., Detection of pesticides in seized illegal cannabis plants. Anal. Methods. 6 (2014), 515–520, 10.1039/C3AY40930A.
    • (2014) Anal. Methods. , vol.6 , pp. 515-520
    • Schneider, S.1    Bebing, R.2    Dauberschmidt, C.3
  • 89
    • 84862167879 scopus 로고    scopus 로고
    • Detection of JWH-018 and JWH-073 by UPLC-MS–MS in postmortem whole blood casework
    • Shanks, K.G., Dahn, T., Terrell, A.R., Detection of JWH-018 and JWH-073 by UPLC-MS–MS in postmortem whole blood casework. J. Anal. Toxicol. 36 (2012), 145–152, 10.1093/jat/bks013.
    • (2012) J. Anal. Toxicol. , vol.36 , pp. 145-152
    • Shanks, K.G.1    Dahn, T.2    Terrell, A.R.3
  • 92
    • 84892460794 scopus 로고    scopus 로고
    • Comparison between self-report of cannabis use and toxicological detection of THC/THCCOOH in blood and THC in oral fluid in drivers in a roadside survey
    • Van der Linden, T., Silverans, P., Verstraete, A.G., Comparison between self-report of cannabis use and toxicological detection of THC/THCCOOH in blood and THC in oral fluid in drivers in a roadside survey. Drug Test Anal. 6 (2014), 137–142, 10.1002/dta.1517.
    • (2014) Drug Test Anal. , vol.6 , pp. 137-142
    • Van der Linden, T.1    Silverans, P.2    Verstraete, A.G.3
  • 93
    • 84872855833 scopus 로고    scopus 로고
    • Driving under the influence of cannabis: pitfalls, validation, and quality control of a UPLCMS/MS method for the quantification of tetrahydrocannabinol in oral fluid collected with statsure, quantisal, or certus collector
    • Wille, S.M., Di Fazio, V., RamírezFernandez, M.M., Kummer, N., Samyn, N., Driving under the influence of cannabis: pitfalls, validation, and quality control of a UPLCMS/MS method for the quantification of tetrahydrocannabinol in oral fluid collected with statsure, quantisal, or certus collector. Ther. Drug Monit. 35 (2013), 101–111.
    • (2013) Ther. Drug Monit. , vol.35 , pp. 101-111
    • Wille, S.M.1    Di Fazio, V.2    RamírezFernandez, M.M.3    Kummer, N.4    Samyn, N.5
  • 94
    • 84924759227 scopus 로고    scopus 로고
    • ® screening and oral fluid quantification after Quantisal™ collection for roadside drug detection via a controlled study with chronic cannabis users
    • ® screening and oral fluid quantification after Quantisal™ collection for roadside drug detection via a controlled study with chronic cannabis users. Drug Test Anal. 7 (2015), 178–186, 10.1002/dta.1660.
    • (2015) Drug Test Anal. , vol.7 , pp. 178-186
    • Wille, S.M.1    Di Fazio, V.2    Toennes, S.W.3    van Wel, J.H.4    Ramaekers, J.G.5    Samyn, N.6
  • 95
    • 45849093256 scopus 로고    scopus 로고
    • Determination of cannabinoids in whole blood by UPLC-MS-MS
    • Jamey, C., Szwarc, E., Tracqui, A., Ludes, B., Determination of cannabinoids in whole blood by UPLC-MS-MS. J. Anal. Toxicol. 32 (2008), 349–354, 10.1093/jat/32.5.349.
    • (2008) J. Anal. Toxicol. , vol.32 , pp. 349-354
    • Jamey, C.1    Szwarc, E.2    Tracqui, A.3    Ludes, B.4
  • 96
    • 0027432964 scopus 로고
    • Resolution of chiral cannabinoids on amylose tris(3, 5-Dimethylphenylcarbamate) chiral stationary-Phase − effects of structural features and mobile-Phase additives
    • Levin, S., Abulafi, S., Zahalka, J., Mechoulam, R., Resolution of chiral cannabinoids on amylose tris(3, 5-Dimethylphenylcarbamate) chiral stationary-Phase − effects of structural features and mobile-Phase additives. J. Chromatogr. A 654 (1993), 53–64, 10.1016/0021-9673(93)83064-Y.
    • (1993) J. Chromatogr. A , vol.654 , pp. 53-64
    • Levin, S.1    Abulafi, S.2    Zahalka, J.3    Mechoulam, R.4
  • 98
    • 77956697081 scopus 로고    scopus 로고
    • Determination of kinetic parameters of enantiomerization of benzothiadiazines by DCXplorer
    • Cannazza, G., Carrozzo, M.M., Battisti, U., Braghiroli, D., Parenti, C., Troisi, A., Troisi, L., Determination of kinetic parameters of enantiomerization of benzothiadiazines by DCXplorer. Chirality 22 (2010), 789–797, 10.1002/chir.
    • (2010) Chirality , vol.22 , pp. 789-797
    • Cannazza, G.1    Carrozzo, M.M.2    Battisti, U.3    Braghiroli, D.4    Parenti, C.5    Troisi, A.6    Troisi, L.7
  • 99
    • 80655136977 scopus 로고    scopus 로고
    • Molecular modeling studies, synthesis, configurational stability and biological activity of 8-chloro-2,3,5,6-tetrahydro-3,6-dimethyl-pyrrolo[1,2,3-de]-1,2,4-benzothiadiazine 1,1-dioxide
    • Battisti, U.M., Carrozzo, M.M., Cannazza, G., Puia, G., Troisi, L., Braghiroli, D., Parenti, C., Jozwiak, K., Molecular modeling studies, synthesis, configurational stability and biological activity of 8-chloro-2,3,5,6-tetrahydro-3,6-dimethyl-pyrrolo[1,2,3-de]-1,2,4-benzothiadiazine 1,1-dioxide. Bioorg. Med. Chem. 19 (2011), 7111–7119, 10.1016/j.bmc.2011.09.06.
    • (2011) Bioorg. Med. Chem. , vol.19 , pp. 7111-7119
    • Battisti, U.M.1    Carrozzo, M.M.2    Cannazza, G.3    Puia, G.4    Troisi, L.5    Braghiroli, D.6    Parenti, C.7    Jozwiak, K.8
  • 100
    • 67649382946 scopus 로고    scopus 로고
    • On-line racemization by high-performance liquid chromatography
    • Cannazza, G., Carrozzo, M.M., Battisti, U., Braghiroli, D., Parenti, C., On-line racemization by high-performance liquid chromatography. J. Chromatogr. A. 1216 (2009), 5655–5659, 10.1016/j.chroma.2009.05.057.
    • (2009) J. Chromatogr. A. , vol.1216 , pp. 5655-5659
    • Cannazza, G.1    Carrozzo, M.M.2    Battisti, U.3    Braghiroli, D.4    Parenti, C.5
  • 102
    • 78649889573 scopus 로고    scopus 로고
    • Epimerization and hydrolysis of 3,6-dimethyl-2,3,5,6-tetrahydro[1,2,4]thiadiazino[6,5,4-hi]indole 1,1-dioxide
    • Carrozzo, M.M., Cannazza, G., Battisti, U., Braghiroli, D., Troisi, L., Parenti, C., Epimerization and hydrolysis of 3,6-dimethyl-2,3,5,6-tetrahydro[1,2,4]thiadiazino[6,5,4-hi]indole 1,1-dioxide. J. Chromatogr. A 1217 (2010), 8136–8145, 10.1016/j.chroma.2010.10.044.
    • (2010) J. Chromatogr. A , vol.1217 , pp. 8136-8145
    • Carrozzo, M.M.1    Cannazza, G.2    Battisti, U.3    Braghiroli, D.4    Troisi, L.5    Parenti, C.6
  • 103
    • 55049103946 scopus 로고    scopus 로고
    • Enantiomerization and hydrolysis of (±)-7-chloro-3-methyl-3, 4-dihydro-2H-1, 2, 4-benzothiadiazine 1, 1-dioxide by stopped-flow multidimensional high-performance liquid chromatography
    • Cannazza, G., Carrozzo, M.M., Braghiroli, D., Parenti, C., Enantiomerization and hydrolysis of (±)-7-chloro-3-methyl-3, 4-dihydro-2H-1, 2, 4-benzothiadiazine 1, 1-dioxide by stopped-flow multidimensional high-performance liquid chromatography. J. Chromatogr. A 1212 (2008), 41–47, 10.1016/j.chroma.2008.09.087.
    • (2008) J. Chromatogr. A , vol.1212 , pp. 41-47
    • Cannazza, G.1    Carrozzo, M.M.2    Braghiroli, D.3    Parenti, C.4
  • 104
    • 54049129637 scopus 로고    scopus 로고
    • Enantiomerization of chiral 2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide by stopped-flow multidimensional HPLC
    • Cannazza, G., Carrozzo, M.M., Braghiroli, D., Parenti, C., Enantiomerization of chiral 2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide by stopped-flow multidimensional HPLC. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 875 (2008), 192–199, 10.1016/j.jchromb.2008.05.009.
    • (2008) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.875 , pp. 192-199
    • Cannazza, G.1    Carrozzo, M.M.2    Braghiroli, D.3    Parenti, C.4
  • 105
    • 84908114125 scopus 로고    scopus 로고
    • Development of an in vitro liquid chromatography-mass spectrometry method to evaluate stereo and chemical stability of new drug candidates employing immobilized artificial membrane column
    • Cannazza, G., Battisti, U.M., Carrozzo, M.M., Cazzato, A.S., Braghiroli, D., Parenti, C., Troisi, L., Development of an in vitro liquid chromatography-mass spectrometry method to evaluate stereo and chemical stability of new drug candidates employing immobilized artificial membrane column. J. Chromatogr. A. 1363 (2014), 216–225, 10.1016/j.chroma.2014.05.073.
    • (2014) J. Chromatogr. A. , vol.1363 , pp. 216-225
    • Cannazza, G.1    Battisti, U.M.2    Carrozzo, M.M.3    Cazzato, A.S.4    Braghiroli, D.5    Parenti, C.6    Troisi, L.7
  • 107
    • 16244383829 scopus 로고    scopus 로고
    • Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptors
    • Hanus, L.O., Tchilibon, S., Ponde, D.E., Breuer, A., Fride, E., Mechoulam, R., Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptors. Org. Biomol. Chem. 3 (2005), 1116–1123, 10.1039/b416943c.
    • (2005) Org. Biomol. Chem. , vol.3 , pp. 1116-1123
    • Hanus, L.O.1    Tchilibon, S.2    Ponde, D.E.3    Breuer, A.4    Fride, E.5    Mechoulam, R.6
  • 108
    • 0027989845 scopus 로고
    • Role of hydroxyl groups in chiral recognition of cannabinoids by carbamated amylose
    • Abu-Lafi, S., Sterin, M., Levin, S., Role of hydroxyl groups in chiral recognition of cannabinoids by carbamated amylose. J. Chromatogr. A 679 (1994), 47–58, 10.1016/0021-9673(94)80310-2.
    • (1994) J. Chromatogr. A , vol.679 , pp. 47-58
    • Abu-Lafi, S.1    Sterin, M.2    Levin, S.3
  • 109
    • 84978010712 scopus 로고
    • Heart-cut bidimensional achiral-chiral liquid chromatography applied to the evaluation of stereoselective metabolism, in vivo biological activity and brain response to chiral drug candidates targeting the central nervous system
    • Battisti, U.M., Citti, C., Larini, M., Ciccarella, G., Stasiak, N., Troisi, L., Braghiroli, D., Parenti, C., Zoli, M., Cannazza, G., Heart-cut bidimensional achiral-chiral liquid chromatography applied to the evaluation of stereoselective metabolism, in vivo biological activity and brain response to chiral drug candidates targeting the central nervous system. J. Chromatogr. A 2016 (1443), 152–161, 10.1016/j.chroma.2016.03.027.
    • (1443) J. Chromatogr. A , vol.2016 , pp. 152-161
    • Battisti, U.M.1    Citti, C.2    Larini, M.3    Ciccarella, G.4    Stasiak, N.5    Troisi, L.6    Braghiroli, D.7    Parenti, C.8    Zoli, M.9    Cannazza, G.10
  • 110
    • 80052555187 scopus 로고    scopus 로고
    • Qualitative and quantitative analysis of THC, 11-hydroxy-THC and 11-nor-9-carboxy-THC in whole blood by ultra-performance liquid chromatography/tandem mass spectrometry., Rapid Commun
    • Simões, S.S., Ajenjo, A.C., Dias, M.J., Qualitative and quantitative analysis of THC, 11-hydroxy-THC and 11-nor-9-carboxy-THC in whole blood by ultra-performance liquid chromatography/tandem mass spectrometry., Rapid Commun. Mass Spectrom. 25 (2011), 2603–2610, 10.1002/rcm.5165.
    • (2011) Mass Spectrom. , vol.25 , pp. 2603-2610
    • Simões, S.S.1    Ajenjo, A.C.2    Dias, M.J.3
  • 111
    • 84872778316 scopus 로고    scopus 로고
    • Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR
    • Happyana, N., Agnolet, S., Muntendam, R., Van Dam, A., Schneider, B., Kayser, O., Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR. Phytochemistry 87 (2013), 51–59, 10.1016/j.phytochem.2012.11.001.
    • (2013) Phytochemistry , vol.87 , pp. 51-59
    • Happyana, N.1    Agnolet, S.2    Muntendam, R.3    Van Dam, A.4    Schneider, B.5    Kayser, O.6
  • 112
    • 0343006751 scopus 로고    scopus 로고
    • Simultaneous determination of THC-COOH and THC-COOH-glucuronide in urine samples by LC/MS/MS
    • Weinmann, W., Vogt, S., Goerke, R., Müller, C., Bromberger, A., Simultaneous determination of THC-COOH and THC-COOH-glucuronide in urine samples by LC/MS/MS. Forensic Sci. Int. 113 (2000), 381–387, 10.1016/S0379-0738(00)00210-3.
    • (2000) Forensic Sci. Int. , vol.113 , pp. 381-387
    • Weinmann, W.1    Vogt, S.2    Goerke, R.3    Müller, C.4    Bromberger, A.5
  • 113
    • 84930944864 scopus 로고    scopus 로고
    • Development of a simple and sensitive HPLC-UV method for the simultaneous determination of cannabidiol and 9 −tetrahydrocannabinol in rat plasma
    • Zgair, A., Wong, J.C.M., Sabri, A., Fischer, P.M., Barrett, D.A., Constantinescu, C.S., Gershkovich, P., Development of a simple and sensitive HPLC-UV method for the simultaneous determination of cannabidiol and 9 −tetrahydrocannabinol in rat plasma. J. Pharm. Biomed. Anal. J. Pharm. Biomed. 114 (2015), 145–151, 10.1016/j.jpba.2015.05.019.
    • (2015) J. Pharm. Biomed. Anal. J. Pharm. Biomed. , vol.114 , pp. 145-151
    • Zgair, A.1    Wong, J.C.M.2    Sabri, A.3    Fischer, P.M.4    Barrett, D.A.5    Constantinescu, C.S.6    Gershkovich, P.7
  • 114
    • 13444293453 scopus 로고    scopus 로고
    • Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?, Rapid Commun
    • Stokvis, E., Rosing, H., Beijnen, J.H., Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?, Rapid Commun. Mass Spectrom. 19 (2005), 401–407, 10.1002/rcm.1790.
    • (2005) Mass Spectrom. , vol.19 , pp. 401-407
    • Stokvis, E.1    Rosing, H.2    Beijnen, J.H.3
  • 115
    • 4444273825 scopus 로고    scopus 로고
    • Quantitative analysis of cannabinoids from Cannabis sativa using 1H-NMR
    • Hazekamp, A., Choi, Y.H., Verpoorte, R., Quantitative analysis of cannabinoids from Cannabis sativa using 1H-NMR. Chem. Pharm. Bull. (Tokyo). 52 (2004), 718–721, 10.1248/cpb.52.718.
    • (2004) Chem. Pharm. Bull. (Tokyo). , vol.52 , pp. 718-721
    • Hazekamp, A.1    Choi, Y.H.2    Verpoorte, R.3
  • 117
    • 0035810309 scopus 로고    scopus 로고
    • Infrared spectroscopy analysis of hemp (Cannabis sativa) after selective delignification by Bjerkandera sp. at different nitrogen levels
    • Dorado, J., Almendros, G., Field, J.A., Sierra-Alvarez, R., Infrared spectroscopy analysis of hemp (Cannabis sativa) after selective delignification by Bjerkandera sp. at different nitrogen levels. Enzyme Microb. Technol. 28 (2001), 550–559, 10.1016/S0141-0229(00)00363-X.
    • (2001) Enzyme Microb. Technol. , vol.28 , pp. 550-559
    • Dorado, J.1    Almendros, G.2    Field, J.A.3    Sierra-Alvarez, R.4
  • 118
    • 84929133512 scopus 로고    scopus 로고
    • Comparison between drug screening by immunoassay and ultra-high performance liquid chromatography/high-resolution time-of-flight mass spectrometry in post-mortem urine
    • Sundström, M., Pelander, A., Ojanperä, I., Comparison between drug screening by immunoassay and ultra-high performance liquid chromatography/high-resolution time-of-flight mass spectrometry in post-mortem urine. Drug Test Anal. 7 (2015), 420–427, 10.1002/dta.1683.
    • (2015) Drug Test Anal. , vol.7 , pp. 420-427
    • Sundström, M.1    Pelander, A.2    Ojanperä, I.3
  • 119
    • 84991325439 scopus 로고    scopus 로고
    • Detection of cannabinoids by ELISA and GC?MS methods in a hair sample previously used to detect other drugs of abuse
    • Tassoni, M., Cippitelli, G., Ottaviani, R., Detection of cannabinoids by ELISA and GC?MS methods in a hair sample previously used to detect other drugs of abuse. J. Anal Toxicol. 40 (2016), 408–413.
    • (2016) J. Anal Toxicol. , vol.40 , pp. 408-413
    • Tassoni, M.1    Cippitelli, G.2    Ottaviani, R.3
  • 122
    • 84555189581 scopus 로고    scopus 로고
    • Metabolite analysis of cannabis sativa L. by NMR spectroscopy
    • Isvett, R.V., Flores-Sanchez, Josefina, Hae Choi, Young, Metabolite analysis of cannabis sativa L. by NMR spectroscopy. Methods Mol. Biol. 815 (2011), 363–375.
    • (2011) Methods Mol. Biol. , vol.815 , pp. 363-375
    • Isvett, R.V.1    Flores-Sanchez, J.2    Hae Choi, Y.3
  • 123
    • 84890122646 scopus 로고    scopus 로고
    • Time dependent metabolomics and transcriptional analysis of cannabinoid biosynthesis in C annabis sativa var. bedrobinol and bediol grown under standardized condition and with genetic homogeneity
    • Muntendam, R., Happyana, N., Erkelens, T., Time dependent metabolomics and transcriptional analysis of cannabinoid biosynthesis in C annabis sativa var. bedrobinol and bediol grown under standardized condition and with genetic homogeneity. Online Int. J. Med. Plants Res. 1 (2012), 31–40.
    • (2012) Online Int. J. Med. Plants Res. , vol.1 , pp. 31-40
    • Muntendam, R.1    Happyana, N.2    Erkelens, T.3
  • 124
    • 3042582999 scopus 로고    scopus 로고
    • Metabolomic differentiation of cannabis sativa cultivars using 1 H NMR spectroscopy and principal component analysis
    • Choi, Y.H., Kim, H.K., Hazekamp, A., Erkelens, C., Lefeber, A.W.M., Verpoorte, R., Metabolomic differentiation of cannabis sativa cultivars using 1 H NMR spectroscopy and principal component analysis. J. Nat. Prod. 67 (2004), 953–957.
    • (2004) J. Nat. Prod. , vol.67 , pp. 953-957
    • Choi, Y.H.1    Kim, H.K.2    Hazekamp, A.3    Erkelens, C.4    Lefeber, A.W.M.5    Verpoorte, R.6
  • 125
    • 33746965554 scopus 로고    scopus 로고
    • The assessment of plant metabolite profiles by NMR-based methodologies
    • Elaine Holmes, C.S., Huiru Tang, Yulan Wang, Holmes, E., Tang, H., Wang, Y., Seger, C., The assessment of plant metabolite profiles by NMR-based methodologies. Planta Med. 72 (2006), 771–785, 10.1055/s-2006-946682.
    • (2006) Planta Med. , vol.72 , pp. 771-785
    • Elaine Holmes, C.S.1    Tang, H.2    Wang, Y.3    Holmes, E.4    Tang, H.5    Wang, Y.6    Seger, C.7
  • 127
    • 67649385775 scopus 로고    scopus 로고
    • Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry
    • Grata, E., Guillarme, D., Glauser, G., Boccard, J., Carrupt, P.A., Veuthey, J.L., Rudaz, S., Wolfender, J.L., Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry. J. Chromatogr. A. 1216 (2009), 5660–5668, 10.1016/j.chroma.2009.05.069.
    • (2009) J. Chromatogr. A. , vol.1216 , pp. 5660-5668
    • Grata, E.1    Guillarme, D.2    Glauser, G.3    Boccard, J.4    Carrupt, P.A.5    Veuthey, J.L.6    Rudaz, S.7    Wolfender, J.L.8
  • 128
    • 84922864949 scopus 로고    scopus 로고
    • Current approaches and challenges for the metabolite profiling of complex natural extracts
    • Wolfender, J.-L., Marti, G., Thomas, A., Bertrand, S., Current approaches and challenges for the metabolite profiling of complex natural extracts. J. Chromatogr. A. 1382 (2015), 136–164, 10.1016/j.chroma.2014.10.091.
    • (2015) J. Chromatogr. A. , vol.1382 , pp. 136-164
    • Wolfender, J.-L.1    Marti, G.2    Thomas, A.3    Bertrand, S.4
  • 129
    • 84907097738 scopus 로고    scopus 로고
    • Study of leaf metabolome modifications induced by UV-C radiations in representative vitis, cissus and cannabis species by LC-MS based metabolomics and antioxidant assays
    • Marti, G., Schnee, S., Andrey, Y., Simoes-pires, C., Carrupt, P., Wolfender, J., Gindro, K., Study of leaf metabolome modifications induced by UV-C radiations in representative vitis, cissus and cannabis species by LC-MS based metabolomics and antioxidant assays. Molecules 19 (2014), 14004–14021, 10.3390/molecules190914004.
    • (2014) Molecules , vol.19 , pp. 14004-14021
    • Marti, G.1    Schnee, S.2    Andrey, Y.3    Simoes-pires, C.4    Carrupt, P.5    Wolfender, J.6    Gindro, K.7
  • 130
    • 85041755681 scopus 로고    scopus 로고
    • A metabolomic approach applied to a liquid chromatography coupled to high-resolution tandem mass spectrometry method (HPLC-ESI-HRMS/MS): towards the comprehensive evaluation of the chemical composition of cannabis medicinal extracts
    • Citti, C., Battisti, U.M., Braghiroli, D., Ciccarella, G., Schmid, M., Vandelli, M.A., Cannazza, G., A metabolomic approach applied to a liquid chromatography coupled to high-resolution tandem mass spectrometry method (HPLC-ESI-HRMS/MS): towards the comprehensive evaluation of the chemical composition of cannabis medicinal extracts. submitted to Phytochem. Anal., 2017.
    • (2017) submitted to Phytochem. Anal.
    • Citti, C.1    Battisti, U.M.2    Braghiroli, D.3    Ciccarella, G.4    Schmid, M.5    Vandelli, M.A.6    Cannazza, G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.