Fast liquid chromatography/tandem mass spectrometry determination of cannabinoids in micro volume blood samples after dabsyl derivatization

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 905, Issue , 2012, Pages 85-95

  Lacroix, C ^a   Saussereau, E ^a  

^a Pharmacokinetic and Toxicology Laboratory   (France)

Author keywords

Cannabinoids; Dabsyl derivatization; LC MS MS; Micro volume

Indexed keywords

ANALYTICAL COLUMNS; BLOOD SAMPLES; CANNABINOIDS; CANNABINOL; CHROMATOGRAPHIC SEPARATIONS; COMPARATIVE STUDIES; DABSYL CHLORIDES; DERIVATIZATIONS; ELECTROSPRAY MODES; ELECTROSPRAYS; IONIZABLE GROUPS; IONIZATION EFFICIENCY; LC/MS-MS; LIMITS OF DETECTION; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LOWER LIMITS; MICROVOLUMES; NON-POLAR; PHENOLIC OH GROUP; PROTEIN PRECIPITATION; PROTONATED; QUANTITATIVE DETERMINATIONS; RUNTIMES; SIGNAL INTENSITIES; TERTIARY AMINE;

ACETONITRILE; CHLORINE COMPOUNDS; ELECTROSPRAY IONIZATION; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHENOLS;

BLOOD;

11 HYDROXY TETRAHYDROCANNABINOL; 11 NOR 9 CARBOXY TETRAHYDROCANNABINOL; CANNABIDIOL; CANNABINOID DERIVATIVE; CANNABINOL; CHLORIDE; DABSYL CHLORIDE; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; DERIVATIZATION; DRUG DETERMINATION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; PRECIPITATION; PRIORITY JOURNAL; PROCESS DESIGN; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

CANNABINOIDS; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HUMANS; LIMIT OF DETECTION; LINEAR MODELS; P-DIMETHYLAMINOAZOBENZENE; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 84865714959     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.08.006     Document Type: Article

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