Development and validation of an LC-MS/MS method for quantification of Δ9-tetrahydrocannabinolic acid A (THCA-A), THC, CBN and CBD in hair

Journal of Mass Spectrometry

Volumn 48, Issue 2, 2013, Pages 227-233

  Roth, Nadine ^a,b   Moosmann, Bjoern ^a,b   Auwärter, Volker ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

9 tetrahydrocannabinolic acid A; cannabinoids; hair analysis; LC MS MS; validation

Indexed keywords

ACCURACY AND PRECISION; ALKALINE HYDROLYSIS; ANALYTES; CANNABINOIDS; CANNABINOL; ELECTROSPRAYS; EXTRACTION EFFICIENCIES; GRADIENT ELUTION; HAIR ANALYSIS; HAIR EXTRACTS; IN-VIVO; INTERNAL STANDARDS; LC-MS/MS; LIMIT OF DETECTION; LINEAR CALIBRATION; LOWER LIMIT OF QUANTIFICATIONS; PEAK AREA; PILOT STUDIES; REACTION MONITORING; ROOM TEMPERATURE; SIDE STREAMS; TIME-PERIODS; VALIDATION; WEIGHTING FACTORS;

ELECTROSPRAY IONIZATION; FORMIC ACID; METHANOL; PHOSPHOLIPIDS;

EXTRACTION;

2 PROPANOL; ACETIC ACID ETHYL ESTER; ACETONITRILE; CANNABIDIOL; CANNABINOL; DRONABINOL; FORMIC ACID; METHANOL; TETRAHYDROCANNABINOLIC ACID;

ACCURACY; ANALYTICAL EQUIPMENT; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG HAIR LEVEL; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; EXTRACTION; HAIR ANALYSIS; HUMAN; HUMAN TISSUE; HYDROLYSIS; ION MONITORING; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MODEL; MOLECULAR STABILITY; PILOT STUDY; PRACTICE GUIDELINE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ROOM TEMPERATURE; SOLVENT EXTRACTION; STANDARD; SYNTHESIS; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

CANNABINOIDS; CHILD; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HAIR; HUMANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY; TEMPERATURE;

EID: 84873391976     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.3152     Document Type: Article

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