Enantiomerization of chiral 2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide by stopped-flow multidimensional HPLC

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 875, Issue 1, 2008, Pages 192-199

  Cannazza, Giuseppe ^a   Carrozzo, Marina M ^a   Braghiroli, Daniela ^a   Parenti, Carlo ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Enantiomerization; Free energy barriers; Rate constants; S18986; Stopped flow multidimensional HPLC method

Indexed keywords

CHIRALITY; CHROMATOGRAPHIC ANALYSIS; COLUMNS (STRUCTURAL); ENANTIOMERS; ENERGY BARRIERS; FREE ENERGY;

ASYMMETRIC SYNTHESES; BUFFER SOLUTIONS; CHIRAL STATIONARY PHASIS; COLUMN METHODS; DIFFERENT SOLVENTS; ENANTIOMERIZATION; MULTI-DIMENSIONAL; PREPARATIVE HPLC; S18986; STOPPED-FLOW MULTIDIMENSIONAL HPLC METHOD;

RATE CONSTANTS;

2,3 DIHYDRO 3,4 CYCLOPENTANO 1,2,4 BENZOTHIADIAZINE 1,1 DIOXIDE; 2,3,3A,4 TETRAHYDRO 1H PYRROLO[2,1 C][1,2,4]BENZOTHIADIAZINE 5,5 DIOXIDE; BENZOTHIADIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CHIRALITY; COLUMN; COLUMN CHROMATOGRAPHY; DEVICE; DRUG DETERMINATION; ENANTIOMER; ENANTIOMERIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; PRIORITY JOURNAL; STOP FLOW MULTIDIMENSIONAL HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

BENZOTHIADIAZINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; OXIDES; STEREOISOMERISM;

EID: 54049129637     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.05.009     Document Type: Article

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