Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy

Clinical Epigenetics

Volumn 9, Issue 1, 2017, Pages

  Mazzone, Roberta ^a,b   Zwergel, Clemens ^a   Mai, Antonello ^a   Valente, Sergio ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

Cancer; DNA methylation; Epigenetics; HDAC inhibitors; Immune checkpoint inhibitors; Immunotherapy

Indexed keywords

DNA METHYLTRANSFERASE INHIBITOR; HISTONE DEACETYLASE INHIBITOR; ANTINEOPLASTIC AGENT; DNA METHYLTRANSFERASE; ENZYME INHIBITOR; MONOCLONAL ANTIBODY;

ADAPTIVE IMMUNITY; ANTIPROLIFERATIVE ACTIVITY; CANCER CLASSIFICATION; CANCER COMBINATION CHEMOTHERAPY; CANCER CONTROL; CANCER IMMUNOTHERAPY; CLINICAL TRIAL (TOPIC); DRUG EFFICACY; DRUG RESEARCH; DRUG SAFETY; DRUG STRUCTURE; EPIGENETICS; FEASIBILITY STUDY; HUMAN; IMMUNOMODULATION; IMMUNOREGULATION; INNATE IMMUNITY; MALIGNANT NEOPLASM; MOUSE MODEL; NONHUMAN; OUTCOME ASSESSMENT; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; REVIEW; ANIMAL; DNA METHYLATION; DRUG EFFECTS; GENETIC EPIGENESIS; GENETICS; IMMUNOTHERAPY; NEOPLASM;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CLINICAL TRIALS AS TOPIC; DNA METHYLATION; DNA MODIFICATION METHYLASES; ENZYME INHIBITORS; EPIGENESIS, GENETIC; HISTONE DEACETYLASE INHIBITORS; HUMANS; IMMUNOTHERAPY; NEOPLASMS;

EID: 85020006586     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/s13148-017-0358-y     Document Type: Review

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