Intratumor OX40 stimulation inhibits IRF1 expression and IL-10 production by Treg cells while enhancing CD40L expression by effector memory T cells

European Journal of Immunology

Volumn 41, Issue 12, 2011, Pages 3615-3626

  Burocchi, Alessia ^a   Pittoni, Paola ^a   Gorzanelli, Andrea ^a   Colombo, Mario P ^a   Piconese, Silvia ^a,b  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

CD40L; IL 10; OX40; T effector memory cells; Treg cells

Indexed keywords

CD40 LIGAND; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 10; OX40 LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MATURATION; CELL MIGRATION; CELL POPULATION; DENDRITIC CELL; DOWN REGULATION; FEMALE; IN VIVO STUDY; MALE; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REGULATORY T LYMPHOCYTE; UPREGULATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; ANTIGENS, CD40; CD40 LIGAND; COCULTURE TECHNIQUES; DOWN-REGULATION; FEMALE; IMMUNOTHERAPY; INTERFERON REGULATORY FACTOR-1; INTERLEUKIN-10; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY; TUMOR MICROENVIRONMENT; TUMOR NECROSIS FACTORS;

EID: 82255186835     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141700     Document Type: Article

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