Antitumor activity of sodium valproate in cultures of human neuroblastoma cells

Anti-Cancer Drugs

Volumn 7, Issue 7, 1996, Pages 766-773

  Cinatl Jr , Jindrich ^a   Cinatl, Jaroslav ^a   Scholz, Martin ^a   Driever, Pablo Hernáiz ^a   Henrich, Dirk ^a   Kabickova, Hana ^b   Vogel, Jens U ^a   Doerr, Hans W ^a   Kornhuber, Bernhard ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Clinical Laboratories Stresovice   (Czech Republic)

Author keywords

Cell differentiation; Lymphokine activated killer cells; Neural cell adhesion molecule; Neuroblastoma; Sodium valproate

Indexed keywords

ANTICONVULSIVE AGENT; ANTINEOPLASTIC AGENT; NERVE CELL ADHESION MOLECULE; ONCOPROTEIN; VALPROIC ACID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOLYSIS; EPILEPSY; HUMAN; HUMAN CELL; IMMUNOGENICITY; LYMPHOKINE ACTIVATED KILLER CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ULTRASTRUCTURE;

EID: 0029909687     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199609000-00008     Document Type: Article

References (28)

1. Parkinson DR, Pluda JM, Cazenave L, et al. Investigational anticancer agents. In: Chabner BA, Longo DL, eds. Cancer chemotherapy and biotherapy. Philadelphia: Lippincott-Raven 1996: 509-27.
2. Warrell RP Jr, de Thé H, Wang Z-Y, Degos L. Review: acute promyelocytic leukemia. N Engl J Med 1993; 329: 177-89.
3. Miller AA, Kurschel E, Osieka R, Schmidt CG. Clinical pharmacology of sodium butyrate in patients with acute leukemia. Eur J Cancer Clin Oncol 1987; 23: 1283-7.
4. Reynolds CP, Kane DJ, Einhorn PA, et al. Response of neuroblastoma to retinoic acid in vitro and in vivo. In: D'Angio GJ, Knudson AG, Evans AE, Seeger RC, eds, Advances in neuroblastoma research 3. New York: Wiley-Liss 1991: 203-11.
5. Kelly MA, Sidell N, Haussler MR. Saturation analysis of cellular retinoid binding proteins: application to retinoic acid resistant human neuroblastoma cells and to human tumors. Biochem Cell Biol 1987; 65 163-72.
6. Chen Z-X, Breitman TR. Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy. Cancer Res 1994; 54: 3494-9.
7. Samid D, Shac S, Sherman LT. Phenylacetate: a novel nontoxic inducer of tumor cell differentiation. Cancer Res 1992; 52: 1988-92.
8. Samid D, Yeh A, Prasanna P. Induction of erythroid differentiation and fetal hemoglobin production in human leukemic cells treated with phenylacetate. Blood 1992; 80: 1576-81.
9. Samid D, Shack S, Myers CE. Selective growth arrest and maturation of prostate cancer cells in vitro by nontoxic, pharmacological concentrations of phenylacetate. J Clin Invest 1993, 91: 2288-95.
10. Cinatl J, Cinatl J, Mainke M, et al. In vitro differentiation of human neuroblastoma cells induced by sodium phenyl acetate. Cancer Lett 1993; 70: 15-24.
11. Samid S, Ram S, Hudgins WR, et al. Selective activity of phenylacetate against malignant gliomas: resemblance to fetal brain damage in phenylketonuria. Cancer Res 1994; 54: 891-5.
12. Brusilow SW, Danney M, Waber LJ, et al. Treatment of episodic hyperammonemia in children with inborn errors of urea synthesis. N Engl J Med 1984; 310: 1630-4.
13. Thibault A, Cooper MR, Figg WD, et al. A phase I and pharmacokinetics study of intravenous phenylacetate in patients with cancer. Cancer Res 1994; 54: 1690-4.
14. Dover GL, Brusilow S, Charache S. Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate. Blood 1994; 84: 339-43.
15. Davis R, Peters DH, McTavish D. Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy. Drugs 1994; 47: 332-72.
16. Collins AF, Dover GJ, Luban NLC. Increased fetal hemoglobin production in patients receiving valproic acid for epilepsy. Blood 1994; 84: 1690-1.
17. Cinatl J Jr, Cinatl J, Mainke M, et al. Aphidicolin selectively kills neuroblastoma cells in vitro. Cancer Lett 1992; 67: 199-206.
18. Cinatl J Jr, Vogel J-U, Cinatl J, et al. Long-term productive human cytomegalovirus infection of a human neuroblastoma cell line. Int J Cancer 1966; 65: 90-6.
19. Volgmann T, Klein-Struckmeier A, Mohr H. A fluorescence-based assay for quantitation of lymphokine-activated killer cell activity. J Immunol Methods 1989; 45: 119.
20. Smith S, Stern A. The effect of aromatic CoA esters on fatty acid synthetase: biosynthesis of ω-phenyl fatty acids. Arch Biochem Biophys 1983; 222: 259-65.
21. Vamecq J, Vallee L, Fontaine M, Nuyts JP, Lambert D, Poupaert J. Preliminary studies about novel strategies to reverse chemoresistance to adriamycin regarding glutathion metabolism, peroxisomal and extraperoxisomal hydroperoxide and valproic acid metabolic pathways. Biol Cell 1993; 77: 17-26.
22. Sidell N, Wada R, Han G, et al. Phenylacetate synergizes with retinoic acid in inducing the differentiation of human neuroblastoma cells. Int J Cancer 1995; 60: 507-14.
23. Boffa LC, Mariani MR, Parker MI. Selective hypermethylation of transcribed nucleosomal DNA by sodium butyrate. Exp Cell Res 1994; 218: 420-23.
24. Gross N, Favre S, Beck D, Meyer M. Differentiation-related expression of adhesion molecules and receptors on human neuroblastoma tissues, cell lines and variants. Int J Cancer 1992; 52: 85-91.
25. Melino G, Piacentini M, Patel K, Annicchiarico-Petruzzelli M, Piredda L, Kemshead JT. Retinoic acid and alpha-difluoromethylornithine induce different expression of neural-specific cell adhesion molecules in differentiating neuroblastoma cells. In. Evans AE, D'Angio GJ, Knudson AG Jr, Seeger RC, eds. Advances in neuroblastoma research 3. New York: Wiley-Liss 1994: 283-91.
26. Nitta T, Yagita H, Sato K, Okumura K. Involvement of CD56 (NKH-1/Leu-19 antigen) as adhesion molecule in natural killer-target cell interaction. J Exp Med 1989; 170: 1757-61.
27. Favrot M, Floret D, Negrier S, et al. Systemic interleukin-2 therapy in children with progressive neuroblastoma after high dose chemotherapy. Bone Marrow Transplant 1989; 4: 499.
28. Rossi AR, Pericle F, Rashleigh S, Janiec J, Djeu JY. Lysis of neuroblastoma cell lines by human natural killer cells activated by interleukin-2 and interleukin-12. Blood 1994; 83: 1323-8.