Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice

Human Molecular Genetics

Volumn 26, Issue 5, 2017, Pages 843-859

  Yang, Dun Sheng ^a,b   Stavrides, Philip ^a   Kumar, Asok ^a,b   Jiang, Ying ^a,b   Mohan, Panaiyur S ^a,b   Ohno, Masuo ^a,b   Dobrenis, Kostantin ^c   Davidson, Cristin D ^c   Saito, Mitsuo ^a,b   Pawlik, Monika ^a   Huo, Chunfeng ^a   Walkley, Steven U ^c   Nixon, Ralph A ^a,b  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ABC TRANSPORTER A1; AMYLOID PRECURSOR PROTEIN; CALPAIN; CATHEPSIN B; CATHEPSIN D; FODRIN; GANGLIOSIDE GM2; LC 3 PROTEIN; NPC 1 PROTEIN; PEPTIDES AND PROTEINS; SEQUESTOSOME 1; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; CYCLODEXTRIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; BRAIN HOMOGENATE; CELL MEMBRANE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HIPPOCAMPAL CA1 REGION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; LIPID STORAGE; LYSOSOME; MALE; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; AMYLOIDOSIS; ANIMAL; BRAIN; DISEASE MODEL; DRUG EFFECTS; HUMAN; LIPID METABOLISM; METABOLISM; NERVE CELL; PATHOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOIDOSIS; ANIMALS; AUTOPHAGY; BRAIN; CYCLODEXTRINS; DISEASE MODELS, ANIMAL; HUMANS; LIPID METABOLISM; LYSOSOMES; MICE; NEURONS;

EID: 85019053494     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddx001     Document Type: Article

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