Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

Cell

Volumn 137, Issue 7, 2009, Pages 1213-1224

  Kwon, Hyock Joo ^a   Abi Mosleh, Lina ^a   Wang, Michael L ^a   Deisenhofer, Johann ^a   Goldstein, Joseph L ^a   Brown, Michael S ^a   Infante, Rodney E ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

CELLBIO

Indexed keywords

25 HYDROXYCHOLESTEROL; CHOLESTEROL; CHOLESTEROL ESTER; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEMBRANE PROTEIN; PROTEIN NIEMANN PICK C1; PROTEIN NPC1; PROTEIN NPC2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CHOLESTEROL TRANSPORT; COMPLEX FORMATION; CONTROLLED STUDY; ENDOCYTOSIS; HYDROLYSIS; LYSOSOME; LYSOSOME MEMBRANE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE;

EID: 67549105629     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2009.03.049     Document Type: Article

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