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Volumn 16, Issue 1, 2016, Pages 150-158

Identification of lysosomal Npc1-binding proteins: Cathepsin D activity is regulated by NPC1

Author keywords

Affinity chromatography; Biomedicine; Cathepsin D; LC MS MS; NPC1; Npc1 binding proteins

Indexed keywords

BINDING PROTEIN; BORTEZOMIB; CATHEPSIN D; PROTEIN NPC1; UNCLASSIFIED DRUG; CARRIER PROTEIN; ENZYME PRECURSOR; LYSOSOMAL PROTEINS; MEMBRANE PROTEIN; NPC1 PROTEIN, HUMAN; PROCATHEPSIN D; PROTEIN;

EID: 84953371042     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201500110     Document Type: Article
Times cited : (13)

References (31)
  • 1
    • 84862532953 scopus 로고    scopus 로고
    • Recommendations for the diagnosis and management of Niemann-Pick disease type C: an update
    • Patterson, M. C., Hendriksz, C. J., Walterfang, M., Sedel, F. et al., Recommendations for the diagnosis and management of Niemann-Pick disease type C: an update. Mol. Genet. Metab. 2012, 106, 330-344.
    • (2012) Mol. Genet. Metab. , vol.106 , pp. 330-344
    • Patterson, M.C.1    Hendriksz, C.J.2    Walterfang, M.3    Sedel, F.4
  • 2
    • 84922104308 scopus 로고    scopus 로고
    • Complex lipid trafficking in Niemann-Pick disease type C
    • Vanier, M. T., Complex lipid trafficking in Niemann-Pick disease type C. J. Inherit. Metab. Dis. 2015, 38, 187-199.
    • (2015) J. Inherit. Metab. Dis. , vol.38 , pp. 187-199
    • Vanier, M.T.1
  • 3
    • 0027976761 scopus 로고
    • The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterol
    • Pentchev, P. G., Brady, R. O., Blanchette-Mackie, E. J., Vanier, M. T. et al., The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterol. Biochim. Biophys. Acta 1994, 1225, 235-243.
    • (1994) Biochim. Biophys. Acta , vol.1225 , pp. 235-243
    • Pentchev, P.G.1    Brady, R.O.2    Blanchette-Mackie, E.J.3    Vanier, M.T.4
  • 4
    • 0023608155 scopus 로고
    • Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts
    • Liscum, L., Faust, J. R., Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts. J. Biol. Chem. 1987, 262, 17002-17008.
    • (1987) J. Biol. Chem. , vol.262 , pp. 17002-17008
    • Liscum, L.1    Faust, J.R.2
  • 5
    • 0037815282 scopus 로고    scopus 로고
    • NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols
    • Frolov, A., Zielinski, S. E., Crowley, J. R., Dudley-Rucker, N. et al., NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols. J. Biol. Chem. 2003, 278, 25517-25525.
    • (2003) J. Biol. Chem. , vol.278 , pp. 25517-25525
    • Frolov, A.1    Zielinski, S.E.2    Crowley, J.R.3    Dudley-Rucker, N.4
  • 6
    • 4644263342 scopus 로고    scopus 로고
    • Elevated endosomal cholesterol levels in Niemann-Pick cells inhibit rab4 and perturb membrane recycling
    • Choudhury, A., Sharma, D. K., Marks, D. L., Pagano, R. E., Elevated endosomal cholesterol levels in Niemann-Pick cells inhibit rab4 and perturb membrane recycling. Mol. Biol. Cell 2004, 15, 4500-4511.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 4500-4511
    • Choudhury, A.1    Sharma, D.K.2    Marks, D.L.3    Pagano, R.E.4
  • 7
    • 77951158568 scopus 로고    scopus 로고
    • Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo
    • Goldman, S. D., Krise, J. P., Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo. J. Biol. Chem. 2010, 285, 4983-4994.
    • (2010) J. Biol. Chem. , vol.285 , pp. 4983-4994
    • Goldman, S.D.1    Krise, J.P.2
  • 8
    • 84890144959 scopus 로고    scopus 로고
    • Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease
    • Sarkar, S., Carroll, B., Buganim, Y., Maetzel, D. et al., Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease. Cell Rep. 2013, 5, 1302-1315.
    • (2013) Cell Rep , vol.5 , pp. 1302-1315
    • Sarkar, S.1    Carroll, B.2    Buganim, Y.3    Maetzel, D.4
  • 9
    • 82755197370 scopus 로고    scopus 로고
    • Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding
    • Deffieu, M. S., Pfeffer, S. R., Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding. Proc. Natl. Acad. Sci. USA 2011, 108, 18932-18936.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 18932-18936
    • Deffieu, M.S.1    Pfeffer, S.R.2
  • 10
    • 78651328466 scopus 로고    scopus 로고
    • A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking
    • Du, X., Kumar, J., Ferguson, C., Schulz, T. A. et al., A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking. J. Cell. Biol. 2011, 192, 121-135.
    • (2011) J. Cell. Biol. , vol.192 , pp. 121-135
    • Du, X.1    Kumar, J.2    Ferguson, C.3    Schulz, T.A.4
  • 11
    • 84874741823 scopus 로고    scopus 로고
    • The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins
    • Poirier, S., Mayer, G., Murphy, S. R., Garver, W. S. et al., The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins. Traffic 2013, 14, 458-469.
    • (2013) Traffic , vol.14 , pp. 458-469
    • Poirier, S.1    Mayer, G.2    Murphy, S.R.3    Garver, W.S.4
  • 12
    • 84953370770 scopus 로고    scopus 로고
    • The Niemann-Pick C1 and caveolin-1 proteins interact to modulate efflux of low density lipoprotein-derived cholesterol from late endocytic compartments
    • Jelinek, D., Heidenreich, R. A., Orlando, R. A., Garver, W. S., The Niemann-Pick C1 and caveolin-1 proteins interact to modulate efflux of low density lipoprotein-derived cholesterol from late endocytic compartments. J. Mol. Biochem. 2014, 3, 14-26.
    • (2014) J. Mol. Biochem. , vol.3 , pp. 14-26
    • Jelinek, D.1    Heidenreich, R.A.2    Orlando, R.A.3    Garver, W.S.4
  • 13
    • 50649106648 scopus 로고    scopus 로고
    • Cathepsin D-many functions of one aspartic protease
    • Benes, P., Vetvicka, V., Fusek, M., Cathepsin D-many functions of one aspartic protease. Crit. Rev. Oncol. Hematol. 2008, 68, 12-28.
    • (2008) Crit. Rev. Oncol. Hematol. , vol.68 , pp. 12-28
    • Benes, P.1    Vetvicka, V.2    Fusek, M.3
  • 14
    • 84865066581 scopus 로고    scopus 로고
    • Microarray expression analysis and identification of serum biomarkers for Niemann-Pick disease type C1
    • Cluzeau, C. V., Watkins-Chow, D. E., Fu, R., Borate, B. et al., Microarray expression analysis and identification of serum biomarkers for Niemann-Pick disease type C1. Hum. Mol. Genet. 2012, 21, 3632-3646.
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 3632-3646
    • Cluzeau, C.V.1    Watkins-Chow, D.E.2    Fu, R.3    Borate, B.4
  • 15
    • 23844448167 scopus 로고    scopus 로고
    • Identification of 25 new mutations in 40 unrelated Spanish Niemann-Pick type C patients: genotype-phenotype correlations
    • Fernandez-Valero, E. M., Ballart, A., Iturriaga, C., Lluch, M. et al., Identification of 25 new mutations in 40 unrelated Spanish Niemann-Pick type C patients: genotype-phenotype correlations. Clin. Genet. 2005, 68, 245-254.
    • (2005) Clin. Genet. , vol.68 , pp. 245-254
    • Fernandez-Valero, E.M.1    Ballart, A.2    Iturriaga, C.3    Lluch, M.4
  • 17
    • 40949122666 scopus 로고    scopus 로고
    • Isolation of lysosomes from tissues and cells by differential and density gradient centrifugation
    • Chapter 3: Unit 3.6
    • Graham, J. M., Isolation of lysosomes from tissues and cells by differential and density gradient centrifugation. Curr. Protoc. Cell Biol. 2001, Chapter 3: Unit 3.6.
    • (2001) Curr. Protoc. Cell Biol.
    • Graham, J.M.1
  • 18
    • 84912103263 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib reduced cholesterol accumulation in fibroblasts from Niemann-Pick type C patients carrying missense mutations
    • Macías-Vidal, J., Girós, M., Guerrero, M., Gascón, P. et al., The proteasome inhibitor bortezomib reduced cholesterol accumulation in fibroblasts from Niemann-Pick type C patients carrying missense mutations. FEBS J. 2014, 281, 4450-4466.
    • (2014) FEBS J , vol.281 , pp. 4450-4466
    • Macías-Vidal, J.1    Girós, M.2    Guerrero, M.3    Gascón, P.4
  • 19
    • 0034637440 scopus 로고    scopus 로고
    • Topological analysis of Niemann-Pick C1 protein reveals that the membrane orientation of the putative sterol-sensing domain is identical to those of 3-hydroxy-3-methylglutaryl-CoA reductase and sterol regulatory element binding protein cleavage-activating protein
    • Davies, J. P., Ioannou, Y. A., Topological analysis of Niemann-Pick C1 protein reveals that the membrane orientation of the putative sterol-sensing domain is identical to those of 3-hydroxy-3-methylglutaryl-CoA reductase and sterol regulatory element binding protein cleavage-activating protein. J. Biol. Chem. 2000, 275, 24367-24374.
    • (2000) J. Biol. Chem. , vol.275 , pp. 24367-24374
    • Davies, J.P.1    Ioannou, Y.A.2
  • 20
    • 0033358193 scopus 로고    scopus 로고
    • Mutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domain
    • Greer, W. L., Dobson, M. J., Girouard, G. S., Byers, D. M. et al., Mutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domain. Am. J. Hum. Genet. 1999, 65, 1252-1260.
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 1252-1260
    • Greer, W.L.1    Dobson, M.J.2    Girouard, G.S.3    Byers, D.M.4
  • 21
    • 0033832873 scopus 로고    scopus 로고
    • Genotype-phenotype relationship of Niemann-Pick disease type C: a possible correlation between clinical onset and levels of NPC1 protein in isolated skin fibroblasts
    • Yamamoto, T., Ninomiya, H., Matsumoto, M., Ohta, Y. et al., Genotype-phenotype relationship of Niemann-Pick disease type C: a possible correlation between clinical onset and levels of NPC1 protein in isolated skin fibroblasts. J. Med. Genet. 2000, 37, 707-712.
    • (2000) J. Med. Genet. , vol.37 , pp. 707-712
    • Yamamoto, T.1    Ninomiya, H.2    Matsumoto, M.3    Ohta, Y.4
  • 22
    • 0034987798 scopus 로고    scopus 로고
    • Niemann-Pick C1 disease: correlations between NPC1 mutations, levels of NPC1 protein, and phenotypes emphasize the functional significance of the putative sterol-sensing domain and of the cysteine-rich luminal loop
    • Millat, G., Marçais, C., Tomasetto, C., Chikh, K. et al., Niemann-Pick C1 disease: correlations between NPC1 mutations, levels of NPC1 protein, and phenotypes emphasize the functional significance of the putative sterol-sensing domain and of the cysteine-rich luminal loop. Am. J. Hum. Genet. 2001, 68, 1373-1385.
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 1373-1385
    • Millat, G.1    Marçais, C.2    Tomasetto, C.3    Chikh, K.4
  • 23
    • 0034714439 scopus 로고    scopus 로고
    • Determinants of NPC1 expression and action: key promoter regions, posttranscriptional control, and the importance of a "cysteine-rich" loop
    • Watari, H., Blanchette-Mackie, E. J., Dwyer, N. K., Watari, M. et al., Determinants of NPC1 expression and action: key promoter regions, posttranscriptional control, and the importance of a "cysteine-rich" loop. Exp. Cell Res. 2000, 259, 247-256.
    • (2000) Exp. Cell Res. , vol.259 , pp. 247-256
    • Watari, H.1    Blanchette-Mackie, E.J.2    Dwyer, N.K.3    Watari, M.4
  • 24
    • 33845972298 scopus 로고    scopus 로고
    • A lysosomal protease, regulates ABCA1-mediated lipid efflux
    • Haidar, B., Kiss, R. S., Sarov-Blat L., Brunet, R. et al., A lysosomal protease, regulates ABCA1-mediated lipid efflux. J. Biol. Chem. 2006, 281, 39971-39981.
    • (2006) J. Biol. Chem. , vol.281 , pp. 39971-39981
    • Haidar, B.1    Kiss, R.S.2    Sarov-Blat, L.3    Brunet, R.4
  • 25
    • 0025897376 scopus 로고
    • Saposin proteins: structure, function, and role in human lysosomal storage disorders
    • O'Brien, J. S., Kishimoto, Y., Saposin proteins: structure, function, and role in human lysosomal storage disorders. FASEB J. 1991, 5, 301-308.
    • (1991) FASEB J , vol.5 , pp. 301-308
    • O'Brien, J.S.1    Kishimoto, Y.2
  • 26
    • 73549105909 scopus 로고    scopus 로고
    • Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice
    • Amritraj, A., Peake, K., Kodam, A., Salio, C. et al., Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice. Am. J. Pathol. 2009, 175, 2540-2556.
    • (2009) Am. J. Pathol. , vol.175 , pp. 2540-2556
    • Amritraj, A.1    Peake, K.2    Kodam, A.3    Salio, C.4
  • 28
    • 1242316263 scopus 로고    scopus 로고
    • Intracellular accumulation of amyloidogenic fragments of amyloid-beta precursor protein in neurons with Niemann-Pick type C defects is associated with endosomal abnormalities
    • Jin, L. W., Shie, F. S., Maezawa, I., Vincent, I. et al., Intracellular accumulation of amyloidogenic fragments of amyloid-beta precursor protein in neurons with Niemann-Pick type C defects is associated with endosomal abnormalities. Am. J. Pathol. 2004, 164, 975-985.
    • (2004) Am. J. Pathol. , vol.164 , pp. 975-985
    • Jin, L.W.1    Shie, F.S.2    Maezawa, I.3    Vincent, I.4
  • 29
    • 84943747165 scopus 로고    scopus 로고
    • Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders
    • Chandra, G., Bagh, M. B., Peng, S., Saha, A. et al., Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders. Hum. Mol. Genet. 2015, 24, 5416-5432.
    • (2015) Hum. Mol. Genet. , vol.24 , pp. 5416-5432
    • Chandra, G.1    Bagh, M.B.2    Peng, S.3    Saha, A.4
  • 30
    • 0037074932 scopus 로고    scopus 로고
    • Neurodegeneration in the Niemann-Pick C mouse: glial involvement
    • German, D. C., Liang, C. L., Song, T., Yazdani, U. et al., Neurodegeneration in the Niemann-Pick C mouse: glial involvement. Neuroscience 2002, 109, 437-450.
    • (2002) Neuroscience , vol.109 , pp. 437-450
    • German, D.C.1    Liang, C.L.2    Song, T.3    Yazdani, U.4
  • 31
    • 84896950203 scopus 로고    scopus 로고
    • Plasma signature of neurological disease in the monogenetic disorder Niemann-Pick Type C
    • Alam, M. S., Getz, M., Yi, S., Kurkewich, J. et al., Plasma signature of neurological disease in the monogenetic disorder Niemann-Pick Type C. J. Biol. Chem. 2014, 289, 8051-8066.
    • (2014) J. Biol. Chem. , vol.289 , pp. 8051-8066
    • Alam, M.S.1    Getz, M.2    Yi, S.3    Kurkewich, J.4


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