Persistent amyloidosis following suppression of Aβ production in a transgenic model of Alzheimer disease

PLoS Medicine

Volumn 2, Issue 12, 2005, Pages 1318-1333

  Jankowsky, Joanna L ^a,b   Slunt, Hilda H ^a,e   Gonzales, Victoria ^a   Savonenko, Alena V ^a   Wen, Jason C ^a   Jenkins, Nancy A ^c   Copeland, Neal G ^c   Younkin, Linda H ^d   Lester, Henry A ^b   Younkin, Steven G ^d   Borchelt, David R ^a,e  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d MAYO CLINIC   (United States)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; DOXYCYCLINE; PROTEINASE INHIBITOR;

ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GENE OVEREXPRESSION; GENETIC MODEL; MOUSE; NONHUMAN; PATHOGENESIS; PATHOLOGY; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TRANSGENIC MOUSE; AMYLOID PLAQUE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; GENE EXPRESSION PROFILING; HUMAN; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; GENE EXPRESSION PROFILING; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PLAQUE, AMYLOID;

EID: 29644440011     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.0020355     Document Type: Article

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