메뉴 건너뛰기




Volumn 173, Issue 3, 2008, Pages 665-681

Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; DNA FRAGMENT; FODRIN; LEUPEPTIN;

EID: 51349125291     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2008.071176     Document Type: Article
Times cited : (151)

References (108)
  • 1
    • 0034849725 scopus 로고    scopus 로고
    • Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease
    • Price JL, Ko AI, Wade MJ, Tsou SK, McKeel DW, Morris JC: Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease. Arch Neurol 2001, 58:1395-1402
    • (2001) Arch Neurol , vol.58 , pp. 1395-1402
    • Price, J.L.1    Ko, A.I.2    Wade, M.J.3    Tsou, S.K.4    McKeel, D.W.5    Morris, J.C.6
  • 4
    • 0028122463 scopus 로고
    • Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
    • West MJ, Coleman PD, Flood DG, Troncoso JC: Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 1994, 344:769-772
    • (1994) Lancet , vol.344 , pp. 769-772
    • West, M.J.1    Coleman, P.D.2    Flood, D.G.3    Troncoso, J.C.4
  • 5
    • 0027474051 scopus 로고
    • Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: A potential molecular basis for neuronal degeneration
    • Saito K, Elce JS, Hamos JE, Nixon RA: Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration. Proc Natl Acad Sci USA 1993, 90:2628-2632
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2628-2632
    • Saito, K.1    Elce, J.S.2    Hamos, J.E.3    Nixon, R.A.4
  • 6
    • 0030836467 scopus 로고    scopus 로고
    • Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease
    • Grynspan F, Griffin WR, Cataldo A, Katayama S, Nixon RA: Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease. Brain Res 1997, 763:145-158
    • (1997) Brain Res , vol.763 , pp. 145-158
    • Grynspan, F.1    Griffin, W.R.2    Cataldo, A.3    Katayama, S.4    Nixon, R.A.5
  • 7
    • 33747388358 scopus 로고    scopus 로고
    • Lysosomal system pathways: Genes to neurodegeneration in Alzheimer's disease
    • Nixon RA, Cataldo AM: Lysosomal system pathways: genes to neurodegeneration in Alzheimer's disease. J Alzheimers Dis 2006, 9:277-289
    • (2006) J Alzheimers Dis , vol.9 , pp. 277-289
    • Nixon, R.A.1    Cataldo, A.M.2
  • 8
    • 0036869740 scopus 로고    scopus 로고
    • Caspase activation in the Alzheimer's disease brain: Tortuous and torturous
    • Rohn TT, Rissman RA, Head E, Cotman CW: Caspase activation in the Alzheimer's disease brain: tortuous and torturous. Drug News Perspect 2002, 15:549-557
    • (2002) Drug News Perspect , vol.15 , pp. 549-557
    • Rohn, T.T.1    Rissman, R.A.2    Head, E.3    Cotman, C.W.4
  • 10
    • 0029912056 scopus 로고    scopus 로고
    • Mechanisms of neuronal death in Alzheimer's disease
    • Cotman CW, Su JH: Mechanisms of neuronal death in Alzheimer's disease. Brain Pathol 1996, 6:493-506
    • (1996) Brain Pathol , vol.6 , pp. 493-506
    • Cotman, C.W.1    Su, J.H.2
  • 11
    • 0028577208 scopus 로고
    • Immunohistochemical evidence for apoptosis in Alzheimer's disease
    • Su JH, Anderson AJ, Cummings BJ, Cotman CW: Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport 1994, 5:2529-2533
    • (1994) Neuroreport , vol.5 , pp. 2529-2533
    • Su, J.H.1    Anderson, A.J.2    Cummings, B.J.3    Cotman, C.W.4
  • 13
    • 0029976253 scopus 로고    scopus 로고
    • DNA damage and apoptosis in Alzheimer's disease: Colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay
    • Anderson AJ, Su JH, Cotman CW: DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay. J Neurosci 1996, 16:1710-1719
    • (1996) J Neurosci , vol.16 , pp. 1710-1719
    • Anderson, A.J.1    Su, J.H.2    Cotman, C.W.3
  • 14
    • 0031110054 scopus 로고    scopus 로고
    • Terminal dUTP nick end labeling (TUNEL) positive cells in the different regions of the brain in normal aging and Alzheimer patients
    • Li WP, Chan WY, Lai HW, Yew DT: Terminal dUTP nick end labeling (TUNEL) positive cells in the different regions of the brain in normal aging and Alzheimer patients. J Mol Neurosci 1997, 8:75-82
    • (1997) J Mol Neurosci , vol.8 , pp. 75-82
    • Li, W.P.1    Chan, W.Y.2    Lai, H.W.3    Yew, D.T.4
  • 15
    • 0030806869 scopus 로고    scopus 로고
    • DNA damage distribution in the human brain as shown by in situ end labeling; area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology
    • Lucassen PJ, Chung WC, Kamphorst W, Swaab DF: DNA damage distribution in the human brain as shown by in situ end labeling; area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology. J Neuropathol Exp Neurol 1997, 56:887-900
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 887-900
    • Lucassen, P.J.1    Chung, W.C.2    Kamphorst, W.3    Swaab, D.F.4
  • 16
    • 0032747486 scopus 로고    scopus 로고
    • Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death
    • Stadelmann C, Deckwerth TL, Srinivasan A, Bancher C, Bruck W, Jellinger K, Lassmann H: Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death. Am J Pathol 1999, 155:1459-1466
    • (1999) Am J Pathol , vol.155 , pp. 1459-1466
    • Stadelmann, C.1    Deckwerth, T.L.2    Srinivasan, A.3    Bancher, C.4    Bruck, W.5    Jellinger, K.6    Lassmann, H.7
  • 19
    • 0036934466 scopus 로고    scopus 로고
    • Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain
    • Su JH, Kesslak JP, Head E, Cotman CW: Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain. Acta Neuropathol (Berl) 2002, 104:1-6
    • (2002) Acta Neuropathol (Berl) , vol.104 , pp. 1-6
    • Su, J.H.1    Kesslak, J.P.2    Head, E.3    Cotman, C.W.4
  • 20
    • 3242811902 scopus 로고    scopus 로고
    • Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease
    • Guo H, Albrecht S, Bourdeau M, Petzke T, Bergeron C, LeBlanc AC: Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease. Am J Pathol 2004, 165:523-531
    • (2004) Am J Pathol , vol.165 , pp. 523-531
    • Guo, H.1    Albrecht, S.2    Bourdeau, M.3    Petzke, T.4    Bergeron, C.5    LeBlanc, A.C.6
  • 23
    • 0035141757 scopus 로고    scopus 로고
    • Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease
    • Rohn TT, Head E, Su JH, Anderson AJ, Bahr BA, Cotman CW, Cribbs DH: Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease. Am J Pathol 2001, 158:189-198
    • (2001) Am J Pathol , vol.158 , pp. 189-198
    • Rohn, T.T.1    Head, E.2    Su, J.H.3    Anderson, A.J.4    Bahr, B.A.5    Cotman, C.W.6    Cribbs, D.H.7
  • 24
    • 0031930313 scopus 로고    scopus 로고
    • Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease
    • Yang F, Sun X, Beech W, Teter B, Wu S, Sigel J, Vinters HV, Frautschy SA, Cole GM: Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease. Am J Pathol 1998, 152:379-389
    • (1998) Am J Pathol , vol.152 , pp. 379-389
    • Yang, F.1    Sun, X.2    Beech, W.3    Teter, B.4    Wu, S.5    Sigel, J.6    Vinters, H.V.7    Frautschy, S.A.8    Cole, G.M.9
  • 26
    • 0036793843 scopus 로고    scopus 로고
    • Caspase-cleaved amyloid precursor protein in Alzheimer's disease
    • Ayala-Grosso C, Ng G, Roy S, Robertson GS: Caspase-cleaved amyloid precursor protein in Alzheimer's disease. Brain Pathol 2002, 12:430-441
    • (2002) Brain Pathol , vol.12 , pp. 430-441
    • Ayala-Grosso, C.1    Ng, G.2    Roy, S.3    Robertson, G.S.4
  • 27
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972, 26:239-257
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 28
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer G, Dallaporta B, Resche-Rigon M: The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 1998, 60:619-642
    • (1998) Annu Rev Physiol , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 29
    • 0033957359 scopus 로고    scopus 로고
    • Morphologic and biochemical hallmarks of apoptosis
    • Saraste A, Pulkki K: Morphologic and biochemical hallmarks of apoptosis. Cardiovasc Res 2000, 45:528-537
    • (2000) Cardiovasc Res , vol.45 , pp. 528-537
    • Saraste, A.1    Pulkki, K.2
  • 30
    • 0035433420 scopus 로고    scopus 로고
    • Four deaths and a funeral: From caspases to alternative mechanisms
    • Leist M, Jaattela M: Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001, 2:589-598
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 589-598
    • Leist, M.1    Jaattela, M.2
  • 31
    • 3042801604 scopus 로고    scopus 로고
    • Morphological features of cell death
    • Ziegler U, Groscurth P: Morphological features of cell death. News Physiol Sci 2004, 19:124-128
    • (2004) News Physiol Sci , vol.19 , pp. 124-128
    • Ziegler, U.1    Groscurth, P.2
  • 32
    • 33748474961 scopus 로고    scopus 로고
    • Challenges in neuronal apoptosis
    • Jellinger KA: Challenges in neuronal apoptosis. Curr Alzheimer Res 2006, 3:377-391
    • (2006) Curr Alzheimer Res , vol.3 , pp. 377-391
    • Jellinger, K.A.1
  • 33
    • 0034830488 scopus 로고    scopus 로고
    • Caspases, apoptosis, and Alzheimer disease: Causation, correlation, and confusion
    • Roth KA: Caspases, apoptosis, and Alzheimer disease: causation, correlation, and confusion. J Neuropathol Exp Neurol 2001, 60:829-838
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 829-838
    • Roth, K.A.1
  • 36
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO: The biochemistry of apoptosis. Nature 2000, 407:770-776
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 37
    • 2342481172 scopus 로고    scopus 로고
    • Programmed cell death: Apoptosis and alternative deathstyles
    • Guimarães CA, Linden R: Programmed cell death: apoptosis and alternative deathstyles. Eur J Biochem 2004, 271:1638-1650
    • (2004) Eur J Biochem , vol.271 , pp. 1638-1650
    • Guimarães, C.A.1    Linden, R.2
  • 38
    • 13544273998 scopus 로고    scopus 로고
    • Caspase-dependent and -independent neuronal death: Two distinct pathways to neuronal injury
    • Stefanis L: Caspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury. Neuroscientist 2005, 11:50-62
    • (2005) Neuroscientist , vol.11 , pp. 50-62
    • Stefanis, L.1
  • 39
    • 0034440818 scopus 로고    scopus 로고
    • Proteases for cell suicide: Functions and regulation of caspases
    • Chang HY, Yang X: Proteases for cell suicide: functions and regulation of caspases. Microbiol Mol Biol Rev 2000, 64:821-846
    • (2000) Microbiol Mol Biol Rev , vol.64 , pp. 821-846
    • Chang, H.Y.1    Yang, X.2
  • 40
    • 0036469777 scopus 로고    scopus 로고
    • Apoptotic DNA fragmentation and tissue homeostasis
    • Zhang J, Xu M: Apoptotic DNA fragmentation and tissue homeostasis. Trends Cell Biol 2002, 12:84-89
    • (2002) Trends Cell Biol , vol.12 , pp. 84-89
    • Zhang, J.1    Xu, M.2
  • 41
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie AH: Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 1980, 284:555-556
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 42
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992, 119:493-501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 43
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy: Dual roles in life and death?
    • Baehrecke EH: Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 2005, 6:505-510
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 44
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: An innocent convict?
    • Levine B, Yuan J: Autophagy in cell death: an innocent convict? J Clin Invest 2005, 115:2679-2688
    • (2005) J Clin Invest , vol.115 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 45
    • 33747881231 scopus 로고    scopus 로고
    • Autophagy in neurodegenerative disease: Friend, foe or turncoat?
    • Nixon RA: Autophagy in neurodegenerative disease: friend, foe or turncoat? Trends Neurosci 2006, 29:528-535
    • (2006) Trends Neurosci , vol.29 , pp. 528-535
    • Nixon, R.A.1
  • 46
    • 0030957959 scopus 로고    scopus 로고
    • Autophagic proteolysis: Control and specificity
    • Blommaart EF, Luiken JJ, Meijer AJ: Autophagic proteolysis: control and specificity. Histochem J 1997, 29:365-385
    • (1997) Histochem J , vol.29 , pp. 365-385
    • Blommaart, E.F.1    Luiken, J.J.2    Meijer, A.J.3
  • 47
    • 0033280667 scopus 로고    scopus 로고
    • Vacuolar import of proteins and organelles from the cytoplasm
    • Klionsky DJ, Ohsumi Y: Vacuolar import of proteins and organelles from the cytoplasm. Annu Rev Cell Dev Biol 1999, 15:1-32
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 1-32
    • Klionsky, D.J.1    Ohsumi, Y.2
  • 48
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • Klionsky DJ, Emr SD: Autophagy as a regulated pathway of cellular degradation. Science 2000, 290:1717-1721
    • (2000) Science , vol.290 , pp. 1717-1721
    • Klionsky, D.J.1    Emr, S.D.2
  • 49
  • 50
    • 0442323561 scopus 로고    scopus 로고
    • Autophagy: In sickness and in health
    • Cuervo AM: Autophagy: in sickness and in health. Trends Cell Biol 2004, 14:70-77
    • (2004) Trends Cell Biol , vol.14 , pp. 70-77
    • Cuervo, A.M.1
  • 51
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB: Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 2005, 120:237-248
    • (2005) Cell , vol.120 , pp. 237-248
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3    Harris, M.H.4    Li, C.5    Lindsten, T.6    Thompson, C.B.7
  • 52
    • 0025283961 scopus 로고
    • Developmental cell death: Morphological diversity and multiple mechanisms
    • Clarke PG: Developmental cell death: morphological diversity and multiple mechanisms. Anat Embryol 1990, 181:195-213
    • (1990) Anat Embryol , vol.181 , pp. 195-213
    • Clarke, P.G.1
  • 53
    • 7744235672 scopus 로고    scopus 로고
    • Death by design: Apoptosis, necrosis and autophagy
    • Edinger AL, Thompson CB: Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol 2004, 16:663-669
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 663-669
    • Edinger, A.L.1    Thompson, C.B.2
  • 54
    • 27644495684 scopus 로고    scopus 로고
    • Autophagic degeneration of motor neurons in a model of slow glutamate excitotoxicity in vitro
    • Matyja E, Taraszewska A, Naganska E, Rafalowska J: Autophagic degeneration of motor neurons in a model of slow glutamate excitotoxicity in vitro. Ultrastruct Pathol 2005, 29:331-339
    • (2005) Ultrastruct Pathol , vol.29 , pp. 331-339
    • Matyja, E.1    Taraszewska, A.2    Naganska, E.3    Rafalowska, J.4
  • 58
    • 0034847176 scopus 로고    scopus 로고
    • Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes
    • Kurt MA, Davies DC, Kidd M, Duff K, Rolph SC, Jennings KH, Howlett DR: Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes. Exp Neurol 2001, 171:59-71
    • (2001) Exp Neurol , vol.171 , pp. 59-71
    • Kurt, M.A.1    Davies, D.C.2    Kidd, M.3    Duff, K.4    Rolph, S.C.5    Jennings, K.H.6    Howlett, D.R.7
  • 60
    • 0033872024 scopus 로고    scopus 로고
    • Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss
    • Takeuchi A, Irizarry MC, Duff K, Saido TC, Hsiao Ashe K, Hasegawa M, Mann DM, Hyman BT, Iwatsubo T: Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. Am J Pathol 2000, 157:331-339
    • (2000) Am J Pathol , vol.157 , pp. 331-339
    • Takeuchi, A.1    Irizarry, M.C.2    Duff, K.3    Saido, T.C.4    Hsiao Ashe, K.5    Hasegawa, M.6    Mann, D.M.7    Hyman, B.T.8    Iwatsubo, T.9
  • 61
    • 0036254139 scopus 로고    scopus 로고
    • Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra
    • Oo TF, Siman R, Burke RE: Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra. Exp Neurol 2002, 175:1-9
    • (2002) Exp Neurol , vol.175 , pp. 1-9
    • Oo, T.F.1    Siman, R.2    Burke, R.E.3
  • 62
    • 0036405495 scopus 로고    scopus 로고
    • Comparison of calpain and caspase activities in the adult rat brain after transient forebrain ischemia
    • Zhang C, Siman R, Xu YA, Mills AM, Frederick JR, Neumar RW: Comparison of calpain and caspase activities in the adult rat brain after transient forebrain ischemia. Neurobiol Dis 2002, 10:289-305
    • (2002) Neurobiol Dis , vol.10 , pp. 289-305
    • Zhang, C.1    Siman, R.2    Xu, Y.A.3    Mills, A.M.4    Frederick, J.R.5    Neumar, R.W.6
  • 63
    • 0031696403 scopus 로고    scopus 로고
    • A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease
    • Tatton NA, lean-Fraser A, Tatton WG, Perl DP, Olanow CW: A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease. Ann Neurol 1998, 44:S142-S148
    • (1998) Ann Neurol , vol.44
    • Tatton, N.A.1    lean-Fraser, A.2    Tatton, W.G.3    Perl, D.P.4    Olanow, C.W.5
  • 65
    • 0030989484 scopus 로고    scopus 로고
    • A simple silver-gold intensification procedure for double DAB labeling studies in electron microscopy
    • Teclemariam-Mesbah R, Wortel J, Romijn HJ, Buijs RM: A simple silver-gold intensification procedure for double DAB labeling studies in electron microscopy. J Histochem Cytochem 1997, 45:619-621
    • (1997) J Histochem Cytochem , vol.45 , pp. 619-621
    • Teclemariam-Mesbah, R.1    Wortel, J.2    Romijn, H.J.3    Buijs, R.M.4
  • 67
    • 0026327404 scopus 로고
    • Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease
    • Cataldo AM, Paskevich PA, Kominami E, Nixon RA: Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease. Proc Natl Acad Sci USA 1991, 88:10998-11002
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10998-11002
    • Cataldo, A.M.1    Paskevich, P.A.2    Kominami, E.3    Nixon, R.A.4
  • 69
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim RW: Cell death during development of the nervous system. Annu Rev Neurosci 1991, 14:453-501
    • (1991) Annu Rev Neurosci , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 72
    • 0002647395 scopus 로고    scopus 로고
    • Hypoxia and related conditions
    • Edited by Graham DI, Lantos PL. New York, Arnold
    • Auer R, Sutherland GR: Hypoxia and related conditions. Greenfield's Neuropathology. Edited by Graham DI, Lantos PL. New York, Arnold, 2002, pp 233-280
    • (2002) Greenfield's Neuropathology , pp. 233-280
    • Auer, R.1    Sutherland, G.R.2
  • 73
    • 1042306482 scopus 로고    scopus 로고
    • Cellular pathology of the central nervous system
    • Edited by Graham DI, Lantos PL. New York, Arnold
    • Graeber MB, Blakemore WF, Kreutzberg GW: Cellular pathology of the central nervous system. Greenfield's Neuropathology. Edited by Graham DI, Lantos PL. New York, Arnold, 2002, pp 123-191
    • (2002) Greenfield's Neuropathology , pp. 123-191
    • Graeber, M.B.1    Blakemore, W.F.2    Kreutzberg, G.W.3
  • 75
    • 0022292558 scopus 로고
    • Lysosomal sequestration of cytosolic enzymes and lysosomal thiol cathepsins
    • Katunuma N, Kominami E: Lysosomal sequestration of cytosolic enzymes and lysosomal thiol cathepsins. Adv Enzyme Regul 1985, 23:159-168
    • (1985) Adv Enzyme Regul , vol.23 , pp. 159-168
    • Katunuma, N.1    Kominami, E.2
  • 77
    • 0028981717 scopus 로고
    • The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice
    • LaFerla FM, Tinkle BT, Bieberich CJ, Haudenschild CC, Jay G: The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nat Genet 1995, 9:21-30
    • (1995) Nat Genet , vol.9 , pp. 21-30
    • LaFerla, F.M.1    Tinkle, B.T.2    Bieberich, C.J.3    Haudenschild, C.C.4    Jay, G.5
  • 80
    • 0029549426 scopus 로고
    • A cautionary note on the use of the TUNEL stain to determine apoptosis
    • Charriaut-Marlangue C, Ben-Ari Y: A cautionary note on the use of the TUNEL stain to determine apoptosis. Neuroreport 1995, 7:61-64
    • (1995) Neuroreport , vol.7 , pp. 61-64
    • Charriaut-Marlangue, C.1    Ben-Ari, Y.2
  • 81
    • 0029294613 scopus 로고
    • In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note
    • Grasl-Kraupp B, Ruttkay-Nedecky B, Koudelka H, Bukowska K, Bursch W, Schulte-Hermann R: In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 1995, 21:1465-1468
    • (1995) Hepatology , vol.21 , pp. 1465-1468
    • Grasl-Kraupp, B.1    Ruttkay-Nedecky, B.2    Koudelka, H.3    Bukowska, K.4    Bursch, W.5    Schulte-Hermann, R.6
  • 82
    • 0037444445 scopus 로고    scopus 로고
    • Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease
    • Yu ZX, Li SH, Evans J, Pillarisetti A, Li H, Li XJ: Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease. J Neurosci 2003, 23:2193-2202
    • (2003) J Neurosci , vol.23 , pp. 2193-2202
    • Yu, Z.X.1    Li, S.H.2    Evans, J.3    Pillarisetti, A.4    Li, H.5    Li, X.J.6
  • 87
    • 27844495164 scopus 로고    scopus 로고
    • Molecular basis of programmed cell death involved in neurodegeneration
    • Krantic S, Mechawar N, Reix S, Quirion R: Molecular basis of programmed cell death involved in neurodegeneration. Trends Neurosci 2005, 28:670-676
    • (2005) Trends Neurosci , vol.28 , pp. 670-676
    • Krantic, S.1    Mechawar, N.2    Reix, S.3    Quirion, R.4
  • 88
    • 33750292972 scopus 로고    scopus 로고
    • Cell death in the nervous system
    • Bredesen DE, Rao RV, Mehlen P: Cell death in the nervous system. Nature 2006, 443:796-802
    • (2006) Nature , vol.443 , pp. 796-802
    • Bredesen, D.E.1    Rao, R.V.2    Mehlen, P.3
  • 89
    • 0028947294 scopus 로고
    • Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: Evidence for early up-regulation of the endosomal-lysosomal system
    • Cataldo AM, Barnett JL, Berman SA, Li J, Quarless S, Bursztajn S, Lippa C, Nixon RA: Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system. Neuron 1995, 14:671-680
    • (1995) Neuron , vol.14 , pp. 671-680
    • Cataldo, A.M.1    Barnett, J.L.2    Berman, S.A.3    Li, J.4    Quarless, S.5    Bursztajn, S.6    Lippa, C.7    Nixon, R.A.8
  • 90
    • 38349046973 scopus 로고    scopus 로고
    • Autophagy, amyloidogenesis and Alzheimer disease
    • Nixon RA: Autophagy, amyloidogenesis and Alzheimer disease. J Cell Sci 2007, 120:4081-4091
    • (2007) J Cell Sci , vol.120 , pp. 4081-4091
    • Nixon, R.A.1
  • 91
    • 0029813177 scopus 로고    scopus 로고
    • Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease
    • Masliah E, Sisk A, Mallory M, Mucke L, Schenk D, Games D: Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease. J Neurosci 1996, 16:5795-5811
    • (1996) J Neurosci , vol.16 , pp. 5795-5811
    • Masliah, E.1    Sisk, A.2    Mallory, M.3    Mucke, L.4    Schenk, D.5    Games, D.6
  • 92
    • 33749074277 scopus 로고    scopus 로고
    • Neuronal macroautophagy: From development to degeneration
    • Boland B, Nixon RA: Neuronal macroautophagy: from development to degeneration. Mol Aspects Med 2006, 27:503-519
    • (2006) Mol Aspects Med , vol.27 , pp. 503-519
    • Boland, B.1    Nixon, R.A.2
  • 95
    • 33847359040 scopus 로고    scopus 로고
    • Autophagy: Paying Charon's toll
    • Yoshimori T: Autophagy: paying Charon's toll. Cell 2007, 128:833-836
    • (2007) Cell , vol.128 , pp. 833-836
    • Yoshimori, T.1
  • 96
    • 34147193472 scopus 로고    scopus 로고
    • Cell biology: Autophagy and cancer
    • Levine B: Cell biology: autophagy and cancer. Nature 2007, 446:745-747
    • (2007) Nature , vol.446 , pp. 745-747
    • Levine, B.1
  • 97
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G: Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 2007, 8:741-752
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 98
    • 0032870475 scopus 로고    scopus 로고
    • Autophagy is activated by apoptotic signalling in sympathetic neurons: An alternative mechanism of death execution
    • Xue L, Fletcher GC, Tolkovsky AM: Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death execution. Mol Cell Neurosci 1999, 14:180-198
    • (1999) Mol Cell Neurosci , vol.14 , pp. 180-198
    • Xue, L.1    Fletcher, G.C.2    Tolkovsky, A.M.3
  • 100
    • 34147141497 scopus 로고    scopus 로고
    • Switch between apoptosis and autophagy: Radiation-induced endoplasmic reticulum stress?
    • Moretti L, Cha YI, Niermann KJ, Lu B: Switch between apoptosis and autophagy: radiation-induced endoplasmic reticulum stress? Cell Cycle 2007, 6:793-798
    • (2007) Cell Cycle , vol.6 , pp. 793-798
    • Moretti, L.1    Cha, Y.I.2    Niermann, K.J.3    Lu, B.4
  • 101
    • 0035881870 scopus 로고    scopus 로고
    • Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29
    • Bauvy C, Gane P, Arico S, Codogno P, Ogier-Denis E: Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29. Exp Cell Res 2001, 268:139-149
    • (2001) Exp Cell Res , vol.268 , pp. 139-149
    • Bauvy, C.1    Gane, P.2    Arico, S.3    Codogno, P.4    Ogier-Denis, E.5
  • 107
    • 33845874899 scopus 로고    scopus 로고
    • Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death
    • Scott RC, Juhasz G, Neufeld TP: Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death. Curr Biol 2007, 17:1-11
    • (2007) Curr Biol , vol.17 , pp. 1-11
    • Scott, R.C.1    Juhasz, G.2    Neufeld, T.P.3
  • 108
    • 85031376295 scopus 로고    scopus 로고
    • Paxinos G, Franklin KBJ: The mouse brain in stereotaxic coordinates, 2nd Edition. London, UK Academic Press, 2001, Figure 33
    • Paxinos G, Franklin KBJ: The mouse brain in stereotaxic coordinates, 2nd Edition. London, UK Academic Press, 2001, Figure 33


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.