Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 17, 2017, Pages E3481-E3489

  Strickson, Sam ^a   Emmerich, Christoph H ^a,c   Goh, Eddy T H ^a,d   Zhang, Jiazhen ^a   Kelsall, Ian R ^a   MacArtney, Thomas ^a   Hastie, C James ^a   Knebel, Axel ^a   Peggie, Mark ^a   Marchesi, Francesco ^b   Arthur, J Simon C ^a   Cohen, Philip ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c Partnership for Assessment and Accreditation of Scientific Practice   (Germany)

^d PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

IL 1; Pellino; TAK1; TRAF6; Ubiquitin

Indexed keywords

COLONY STIMULATING FACTOR 1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIGASE; MYELOID DIFFERENTIATION FACTOR 88; OSTEOCLAST DIFFERENTIATION FACTOR; PELLINO 1; PELLINO 2; PELLINO E3 LIGASE; PROTEIN; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; MYD88 PROTEIN, HUMAN; MYD88 PROTEIN, MOUSE; NUCLEAR PROTEIN; PELI1 PROTEIN, HUMAN; PELI1 PROTEIN, MOUSE; PELI2 PROTEIN, MOUSE; POLYUBIQUITIN; TIFAB PROTEIN, HUMAN; TNFSF11 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ARTICLE; BONE MARROW; BONE MARROW DERIVED MACROPHAGE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HEK293 CELL LINE; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; OSTEOCLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RING FINGER MOTIF; SIGNAL TRANSDUCTION; UBIQUITINATION; AMINO ACID SUBSTITUTION; ANIMAL; GENE KNOCKDOWN; GENETICS; KNOCKOUT MOUSE; METABOLISM; MISSENSE MUTATION;

AMINO ACID SUBSTITUTION; ANIMALS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; MUTATION, MISSENSE; MYELOID DIFFERENTIATION FACTOR 88; NUCLEAR PROTEINS; POLYUBIQUITIN; RANK LIGAND; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; UBIQUITIN-PROTEIN LIGASES;

EID: 85018797476     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1702367114     Document Type: Article

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