Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice

Journal of Immunology

Volumn 191, Issue 5, 2013, Pages 2717-2730

  Pauls, Eduardo ^a,b   Nanda, Sambit K ^a   Smith, Hilary ^a   Toth, Rachel ^a   Arthur, J Simon C ^a   Cohen, Philip ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 2; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EMBRYO; GENE TARGETING; HUMAN; HUMAN CELL; IFN BETA GENE; IL 10 GENE; IL 6 GENE; IMMUNOCOMPETENT CELL; INTERFERON PRODUCTION; MACROPHAGE; MEDIATOR RELEASE; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TNFA GENE; UBIQUITINATION;

ANIMALS; BONE MARROW CELLS; CYTOKINES; DENDRITIC CELLS; GENE KNOCK-IN TECHNIQUES; I-KAPPA B KINASE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INFLAMMATION; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MACROPHAGES; MICE; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANSFECTION;

EID: 84883406297     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1203268     Document Type: Article

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64. Clark, K., M. Peggie, L. Plater, R. J. Sorcek, E. R. Young, J. B. Madwed, J. Hough, E. G. McIver, and P. Cohen. 2011. Novel cross-talk within the IKK family controls innate immunity. Biochem. J. 434: 93-104.
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