The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL

Journal of Biological Chemistry

Volumn 283, Issue 36, 2008, Pages 24871-24880

  Lamothe, Betty ^a   Campos, Alejandro D ^a   Webster, William K ^a   Gopinathan, Ambily ^a   Hur, Lana ^a   Darnay, Bryant G ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; FLOW INTERACTIONS; OLIGOMERIZATION; POLYSACCHARIDES; PROTEINS; ZINC;

ADAPTIVE IMMUNITIES; ADAPTOR MOLECULES; ADAPTOR PROTEINS; AUTOUBIQUITINATION; CYTOKINES; DO-MAINS; FUNCTIONAL DOMAINS; LIGASE ACTIVITIES; LIPOPOLYSACCHARIDE; OSTEOCLAST DIFFERENTIATIONS; POINT MUTATIONS; PROTEASOMAL DEGRADATIONS; SPECIFIC INTERACTIONS; TERMINAL REGIONS; UBIQUITIN; UBIQUITINATION; ZINC FINGERS;

PORT TERMINALS;

I KAPPA B KINASE BETA; I KAPPA B KINASE GAMMA; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; OSTEOCLAST DIFFERENTIATION FACTOR; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN CONJUGATING ENZYME 13; CROC1 PROTEIN, MOUSE; I KAPPA B KINASE; IL6 PROTEIN, HUMAN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEASOME; TNFSF11 PROTEIN, HUMAN; TNFSF11 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; UBC13 PROTEIN, MOUSE; UBE2N PROTEIN, HUMAN; UBE2V1 PROTEIN, HUMAN; UBIQUITIN CONJUGATING ENZYME; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MONOCYTE; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; UBIQUITINATION; ZINC FINGER MOTIF; ANIMAL; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; DRUG EFFECT; GENETICS; INNATE IMMUNITY; METABOLISM; MOUSE MUTANT; OSTEOCLAST; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; HUMANS; I-KAPPA B KINASE; IMMUNITY, NATURAL; INTERLEUKIN-1; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MAP KINASE KINASE 4; MICE; MICE, KNOCKOUT; MONOCYTES; OSTEOCLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; RANK LIGAND; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANSCRIPTION FACTORS; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION; ZINC FINGERS;

EID: 54049133340     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802749200     Document Type: Article

References (30)

1. Chung, J. Y., Park, Y. C., Ye, H., and Wu, H. (2002) J. Cell Sci. 115, 679-688
2. Wu, H., and Arron, J. R. (2003) BioEssays 25, 1096-1105
3. Choi, Y. (2005) Adv. Exp. Med. Biol. 560, 77-82
4. King, C. G., Buckler, J. L., Kobayashi, T., Hannah, J. R., Bassett, G., Kim, T., Pearce, E. L., Kim, G. G., Turka, L. A., and Choi, Y. (2008) J. Immunol. 180, 34-38
5. King, C. G., Kobayashi, T., Cejas, P. J., Kim, T., Yoon, K., Kim, G. K., Chiffoleau, E., Hickman, S. P., Walsh, P. T., Turka, L. A., and Choi, Y. (2006) Nat. Med. 12, 1088-1092
6. Kobayashi, T., Walsh, P. T., Walsh, M. C., Speirs, K. M., Chiffoleau, E., King, C. G., Hancock, W. W., Caamano, J. H., Hunter, C. A., Scott, P., Turka, L. A., and Choi, Y. (2003) Immunity 19, 353-363
7. Lomaga, M. A., Yeh, W. C., Sarosi, I., Duncan, G. S., Furlonger, C., Ho, A., Morony, S., Capparelli, C., Van, G., Kaufman, S., van der Heiden, A., Itie, A., Wakeham, A., Khoo, W., Sasaki, T., Cao, Z., Penninger, J. M., Paige, C. J., Lacey, D. L., Dunstan, C. R., Boyle, W. J., Goeddel, D. V., and Mak, T. W. (1999) Genes Dev. 13, 1015-1024
8. Naito, A., Azuma, S., Tanaka, S., Miyazaki, T., Takaki, S., Takatsu, K., Nakao, K., Nakamura, K., Katsuki, M., Yamamoto, T., and Inoue, J. (1999) Genes Cells 4, 353-362
9. Naito, A., Yoshida, H., Nishioka, E., Satoh, M., Azuma, S., Yamamoto, T., Nishikawa, S., and Inoue, J. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 8766-8771
10. Wang, C., Deng, L., Hong, M., Akkaraju, G. R., Inoue, J., and Chen, Z. J. (2001) Nature 412, 346-351
11. Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C., and Chen, Z. J. (2000) Cell 103, 351-361
12. Lamothe, B., Besse, A., Campos, A. D., Webster, W. K., Wu, H., and Darnay, B. G. (2007) J. Biol. Chem. 282, 4102-4112
13. Lamothe, B., Webster, W. K., Gopinathan, A., Besse, A., Campos, A. D., and Darnay, B. G. (2007) Biochem. Biophys. Res. Commun. 359, 1044-1049
14. Kobayashi, N., Kadono, Y., Naito, A., Matsumoto, K., Yamamoto, T., Tanaka, S., and Inoue, J. (2001) EMBO J. 20, 1271-1280
15. Polek, T. C., Talpaz, M., Darnay, B. G., and Spivak-Kroizman, T. (2003) J. Biol. Chem. 278, 32317-32323
16. Ye, H., Arron, J. R., Lamothe, B., Cirilli, M., Kobayashi, T., Shevde, N. K., Segal, D., Dzivenu, O. K., Vologodskaia, M., Yim, M., Du, K., Singh, S., Pike, J. W., Darnay, B. G., Choi, Y., and Wu, H. (2002) Nature 418, 443-447
17. Darnay, B. G., Ni, J., Moore, P. A., and Aggarwal, B. B. (1999) J. Biol. Chem. 274, 7724-7731
18. Darnay, B. G., Haridas, V., Ni, J., Moore, P. A., and Aggarwal, B. B. (1998) J. Biol. Chem. 273, 20551-20555
19. Wong, A., Lamothe, B., Lee, A., Schlessinger, J., and Lax, I. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 6684-6689
20. Besse, A., Lamothe, B., Campos, A. D., Webster, W. K., Maddineni, U., Lin, S. C., Wu, H., and Darnay, B. G. (2007) J. Biol. Chem. 282, 3918-3928
21. Kobayashi, T., Walsh, M. C., and Choi, Y. (2004) Microbes Infect. 6, 1333-1338
22. Ea, C. K., Deng, L., Xia, Z. P., Pineda, G., and Chen, Z. J. (2006) Mol. Cell 22, 245-257
23. Wu, C. J., Conze, D. B., Li, T., Srinivasula, S. M., and Ashwell, J. D. (2006) Nat. Cell Biol. 8, 398-406
24. Conze, D. B., Wu, C. J., Thomas, J. A., Landstrom, A., and Ashwell, J. D. (2008) Mol. Cell. Biol. 28, 3538-3547
25. Windheim, M., Stafford, M., Peggie, M., and Cohen, P. (2008) Mol. Cell. Biol. 28, 1783-1791
26. Darnay, B. G., Besse, A., Poblenz, A. T., Lamothe, B., and Jacoby, J. J. (2007) Adv. Exp. Med. Biol. 597, 152-159
27. Ishida, N., Hayashi, K., Hoshijima, M., Ogawa, T., Koga, S., Miyatake, Y., Kumegawa, M., Kimura, T., and Takeya, T. (2002) J. Biol. Chem. 277, 41147-41156
28. Takayanagi, H., Kim, S., Koga, T., Nishina, H., Isshiki, M., Yoshida, H., Saiura, A., Isobe, M., Yokochi, T., Inoue, J., Wagner, E. F., Mak, T. W., Kodama, T., and Taniguchi, T. (2002) Dev. Cell 3, 889-901
29. Gohda, J., Matsumura, T., and Inoue, J. (2004) J. Immunol. 173, 2913-2917
30. Mercier, P., Lewis, M. J., Hau, D. D., Saltibus, L. F., Xiao, W., and Spyracopoulos, L. (2007) Protein Sci. 16, 602-614