IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 23, 2014, Pages

  Ben Addi, Abduelhakem ^a   Mambole Dema, Agnes ^a   Brender, Christine ^a   Martin, Stephen R ^a   Janzen, Julia ^a   Kjaer, Sven ^b   Smerdon, Stephen J ^a   Ley, Steven C ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Inflammation; MAP3K8; Nf B

Indexed keywords

I KAPPA B KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN 14 3 3; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHOSPHORYLATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; IMMUNE SYSTEM; IMMUNOBLOTTING; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; RETROVIRUS INFECTION;

INFLAMMATION; MAP3K8; NF-ΚB;

14-3-3 PROTEINS; ANIMALS; CELLS, CULTURED; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; I-KAPPA B KINASE; IMMUNOBLOTTING; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B P50 SUBUNIT; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; SERINE; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84902147332     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1320440111     Document Type: Article

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