Expansions of cytotoxic CD4+CD28- T cells drive excess cardiovascular mortality in rheumatoid arthritis and other chronic inflammatory conditions and are triggered by CMV infection

Frontiers in Immunology

Volumn 8, Issue MAR, 2017, Pages

  Broadley, Iain ^a   Pera, Alejandra ^a,b   Morrow, George ^a   Davies, Kevin A ^a   Kern, Florian ^a  

^a BRIGHTON AND SUSSEX MEDICAL SCHOOL   (United Kingdom)

^b HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

Author keywords

Autoimmune diseases; Cardiovascular diseases; CD4 T cells; Chronic inflammatory disease; Cytotoxic T cells

Indexed keywords

ACICLOVIR; CD28 ANTIGEN; CD4 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; DROSPIRENONE PLUS ETHINYLESTRADIOL; ETANERCEPT; FRACTALKINE; GAMMA INTERFERON; HLA E ANTIGEN; INFLIXIMAB; MAJOR HISTOCOMPATIBILITY ANTIGEN; METFORMIN;

ACUTE CORONARY SYNDROME; ANTIGEN EXPRESSION; BLOOD VESSEL INJURY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL EXPANSION; CELL PROLIFERATION; CHRONIC INFLAMMATION; CORONARY ARTERY DISEASE; CYTOMEGALOVIRUS INFECTION; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; EPIDEMIOLOGICAL MONITORING; HUMAN; HYPERTENSION; IMMUNOTHERAPY; NONHUMAN; REVIEW; RHEUMATOID ARTHRITIS;

EID: 85017121185     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2017.00195     Document Type: Review

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