Clonal expansions in selected TCR BV families of rheumatoid arthritis patients are reduced by treatment with the TNFα inhibitors etanercept and infliximab

Rheumatology International

Volumn 31, Issue 8, 2011, Pages 1023-1029

  Pierer, Matthias ^a   Rossol, Manuela ^a   Kaltenhäuser, Sylke ^a   Arnold, Sybille ^a   Häntzschel, Holm ^a   Baerwald, Christoph ^a   Wagner, Ulf ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

CD28; Clonal expansion; IL 7; Rheumatoid arthritis; T lymphocytes; TNF

Indexed keywords

CD28 ANTIGEN; CYTOKINE; ETANERCEPT; INFLIXIMAB; INTERLEUKIN 7; METHOTREXATE; T LYMPHOCYTE RECEPTOR BETA CHAIN; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG; VARIABLE REGION OF THE T CELL RECEPTOR BETA CHAIN;

ADAPTIVE IMMUNITY; ADULT; ARTICLE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CELL CLONE; CELL COMPARTMENTALIZATION; CELL EXPANSION; CELL SIZE; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CYTOKINE PRODUCTION; DISEASE CONTROL; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; INFLAMMATION; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RHEUMATOID ARTHRITIS; RISK REDUCTION; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; ANTIBODIES, MONOCLONAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CLONE CELLS; FEMALE; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-7; MALE; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 79961173913     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-010-1402-9     Document Type: Article

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