Activating NK-cell receptors co-stimulate CD4+CD28- T cells in patients with rheumatoid arthritis

European Journal of Immunology

Volumn 40, Issue 2, 2010, Pages 378-387

  Fasth, Andreas E R ^a   Björkström, Niklas K ^b   Anthoni, Minna ^b   Malmberg, Karl Johan ^b   Malmström, Vivianne ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cell activation; Cell surface molecules; Co stimulation; Rheumatoid arthritis; T cells

Indexed keywords

CD28 ANTIGEN; NATURAL KILLER CELL RECEPTOR;

ARTICLE; CD4+ T LYMPHOCYTE; CELL FUNCTION; EFFECTOR CELL; FLOW CYTOMETRY; HUMAN; IMMUNOSTIMULATION; INFLAMMATION; LIGATION; NATURAL KILLER CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

AGED; ANTIBODIES; ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, CD3; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ARTHRITIS, RHEUMATOID; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; FEMALE; FLOW CYTOMETRY; HUMANS; INTERFERON-GAMMA; MALE; MIDDLE AGED; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; RECEPTORS, NATURAL KILLER CELL; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 75149130552     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939399     Document Type: Article

References (56)

1. + T cells in severe rheumatoid arthritis. Arthritis Rheum. 1997. 40: 1106-1114.
2. - costimulation-independent T cells in multiple sclerosis. J. Clin. Invest. 2001. 108: 1185-1194.
3. Fasth, A. E., Dastmalchi, M., Rahbar, A., Salomonsson, S., Pandya, J. M., Lindroos, E., Nennesmo, I. et al., T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28(null) T cells. J. Immunol. 2009. 183: 4792-4799.
4. - T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J. Clin. Invest. 1996. 97: 2027-2037.
5. Groh, V., Bruhl, A., El-Gabalawy, H., Nelson, J. L. and Spies, T., Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 2003. 100: 9452-9457.
6. Liuzzo, G., Goronzy, J. J., Yang, H., Kopecky, S. L., Holmes, D. R., Frye, R. L. andWeyand, C. M., Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes. Circulation 2000. 101: 2883-2888.
7. - T-cells in patients with small abdominal aortic aneurysms. Arterioscler. Thromb. Vasc. Biol. 2005. 25: 1347-1352.
8. Fasth, A. E., Cao, D., van Vollenhoven, R., Trollmo, C. and Malmstrom, V., CD28nullCD4+ T cells--characterization of an effector memory T-cell population in patients with rheumatoid arthritis. Scand. J. Immunol. 2004. 60: 199-208.
9. +CD28null T cells clonally expanded in rheumatoid arthritis. J. Immunol. 2000. 165: 1138-1145.
10. + T cells. Blood 2003. 101: 2711-2720.
11. Lanier, L. L., NK cell recognition. Annu. Rev. Immunol. 2005. 23: 225-274.
12. Bryceson, Y. T., March, M. E., Ljunggren, H. G. and Long, E. O., Activation, coactivation, and costimulation of resting human natural killer cells. Immunol. Rev. 2006. 214: 73-91.
13. - T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems. Arthritis Rheum. 2001. 44: 13-20.
14. van Bergen, J., Thompson, A., van der Slik, A., Ottenhoff, T. H., Gussekloo, J. and Koning, F., Phenotypic and functional characterization of CD4 T cells expressing killer Ig-like receptors. J. Immunol. 2004. 173: 6719-6726.
15. Snyder, M. R., Weyand, C. M. and Goronzy, J. J., The double life of NK receptors: stimulation or co-stimulation? Trends Immunol. 2004. 25: 25-32.
16. Goronzy, J. J., Henel, G., Sawai, H., Singh, K., Lee, E. B., Pryshchep, S. and Weyand, C. M., Costimulatory pathways in rheumatoid synovitis and T-cell senescence. Ann. N. Y. Acad. Sci. 2005. 1062: 182-194.
17. Yen, J. H., Moore, B. E., Nakajima, T., Scholl, D., Schaid, D. J., Weyand, C. M. and Goronzy, J. J., Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis. J. Exp. Med. 2001. 193: 1159-1167.
18. Vivier, E. and Anfossi, N., Inhibitory NK-cell receptors on T cells: witness of the past, actors of the future. Nat. Rev. Immunol. 2004. 4: 190-198.
19. Malmberg, K. J., Levitsky, V., Norell, H., de Matos, C. T., Carlsten, M., Schedvins, K., Rabbani, H. et al., IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism. J. Clin. Invest. 2002. 110: 1515-1523.
20. Young, N. T., Uhrberg, M., Phillips, J. H., Lanier, L. L. and Parham, P., Differential expression of leukocyte receptor complex-encoded Ig-like receptors correlates with the transition from effector to memory CTL. J. Immunol. 2001. 166: 3933-3941.
21. Nakajima, T., Goek, O., Zhang, X., Kopecky, S. L., Frye, R. L., Goronzy, J. J. and Weyand, C. M., De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes. Circ. Res. 2003. 93: 106-113.
22. Bouchon, A., Cella, M., Grierson, H. L., Cohen, J. I. and Colonna, M., Activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family. J. Immunol. 2001. 167: 5517-5521.
23. + T-cell clones specific for Mycobacterium tuberculosis. Infect. Immun. 2001. 69: 6022-6029.
24. Bryceson, Y. T., March, M. E., Ljunggren, H. G. and Long, E. O., Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood 2006. 107: 159-166.
25. + T cells by a flow cytometric assay for degranulation. J. Immunol. Methods 2003. 281: 65-78.
26. Perfetto, S. P., Chattopadhyay, P. K. and Roederer, M., Seventeen-colour flow cytometry: unravelling the immune system. Nat. Rev. Immunol. 2004. 4: 648-655.
27. Shibuya, A., Campbell, D., Hannum, C., Yssel, H., Franz-Bacon, K., McClanahan, T., Kitamura, T. et al., DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity 1996. 4: 573-581.
28. Tangye, S. G., Cherwinski, H., Lanier, L. L. and Phillips, J. H., 2B4-mediated activation of human natural killer cells. Mol. Immunol. 2000. 37: 493-501.
29. Nakajima, H., Cella, M., Langen, H., Friedlein, A. and Colonna, M., Activating interactions in human NK cell recognition: the role of 2B4-CD48. Eur. J. Immunol. 1999. 29: 1676-1683.
30. + large granular lymphocytes triggered by a tumor-expressed activating ligand. Leukemia 2002. 16: 855-860.
31. + T cells specific for human cytomegalovirus. Eur. J. Immunol. 2006. 36: 3198-3206.
32. + T cells. J. Immunol. 2005. 174: 1922-1931.
33. + T lymphocytes with cellular maturation. J. Exp. Med. 2006. 203: 2865-2877.
34. Wherry, E. J., Blattman, J. N., Murali-Krishna, K., van der Most, R. and Ahmed, R., Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J. Virol. 2003. 77: 4911-4927.
35. Shin, H., Blackburn, S. D., Blattman, J. N. and Wherry, E. J., Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection. J. Exp. Med. 2007. 204: 941-949.
36. + T cells. Blood 2006. 107: 4781-4789.
37. Jelley-Gibbs, D. M., Dibble, J. P., Filipson, S., Haynes, L., Kemp, R. A. and Swain, S. L., Repeated stimulation of CD4 effector T cells can limit their protective function. J. Exp. Med. 2005. 201: 1101-1112.
38. Iezzi, G., Karjalainen, K. and Lanzavecchia, A., The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity 1998. 8: 89-95.
39. Jelley-Gibbs, D. M., Brown, D. M., Dibble, J. P., Haynes, L., Eaton, S. M. and Swain, S. L., Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation. J. Exp. Med. 2005. 202: 697-706.
40. Steinman, R. M. and Hemmi, H., Dendritic cells: translating innate to adaptive immunity. Curr. Top. Microbiol. Immunol. 2006. 311: 17-58.
41. O'Garra, A., Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity 1998. 8: 275-283.
42. Mocarski, E. S., Jr, Immune escape and exploitation strategies of cytomegaloviruses: impact on and imitation of the major histocompatibility system. Cell. Microbiol. 2004. 6: 707-717.
43. Stauffer, Y., Marguerat, S., Meylan, F., Ucla, C., Sutkowski, N., Huber, B., Pelet, T. and Conrad, B., Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity. Immunity 2001. 15: 591-601.
44. Yokoyama, S., Staunton, D., Fisher, R., Amiot, M., Fortin, J. J. and Thorley-Lawson, D. A., Expression of the Blast-1 activation/adhesion molecule and its identification as CD48. J. Immunol. 1991. 146: 2192-2200.
45. Gasser, S., Orsulic, S., Brown, E. J. and Raulet, D. H., The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 2005. 436: 1186-1190.
46. Groh, V., Rhinehart, R., Randolph-Habecker, J., Topp, M. S., Riddell, S. R. and Spies, T., Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells. Nat. Immunol. 2001. 2: 255-260.
47. +CD28null T cells in rheumatoid arthritis. Arthritis Res. Ther. 2007. 9: R87.
48. Thewissen, M., Linsen, L., Somers, V., Geusens, P., Raus, J. and Stinissen, P., Premature immunosenescence in rheumatoid arthritis and multiple sclerosis patients. Ann. N. Y. Acad. Sci. 2005. 1051: 255-262.
49. + T cells in healthy carriers are continuously driven to replicative exhaustion. J. Immunol. 2005. 175: 8218-8225.
50. Guma, M., Angulo, A., Vilches, C., Gomez-Lozano, N., Malats, N. and Lopez-Botet, M., Imprint of human cytomegalovirus infection on the NK cell receptor repertoire. Blood 2004. 104: 3664-3671.
51. Rolle, A., Mousavi-Jazi, M., Eriksson, M., Odeberg, J., Soderberg-Naucler, C., Cosman, D., Karre, K. and Cerboni, C., Effects of human cytomegalovirus infection on ligands for the activating NKG2D receptor of NK cells: up-regulation of UL16-binding protein (ULBP)1 and ULBP2 is counteracted by the viral UL16 protein. J. Immunol. 2003. 171: 902-908.
52. Tomasec, P., Wang, E. C., Davison, A. J., Vojtesek, B., Armstrong, M., Griffin, C., McSharry, B. P. et al., Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141. Nat. Immunol. 2005. 6: 181-188.
53. Warrington, K. J., Kent, P. D., Frye, R. L., Lymp, J. F., Kopecky, S. L., Goronzy, J. J. and Weyand, C. M., Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study. Arthritis Res. Ther. 2005. 7: R984-R991.
54. - T cells in patients with rheumatoid arthritis. Arthritis Res. Ther. 2003. 5: R210-R213.
55. +) effector CD8 T cells with NK cell-like function in chronic hepatitis C virus infection. J. Immunol. 2008. 181: 4219-4228.
56. Lamoreaux, L., Roederer, M. and Koup, R., Intracellular cytokine optimization and standard operating procedure. Nat. Protoc. 2006. 1: 1507-1516.