Modulation of CD28 expression: Distinct regulatory pathways during activation and replicative senescence

Journal of Immunology

Volumn 162, Issue 11, 1999, Pages 6572-6579

  Vallejo, Abbe N ^a   Brandes, Johann C ^a,b   Weyand, Cornelia M ^a   Goronzy, Jörg J ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD8 ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CELL AGING; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD28; ANTIGENS, CD3; BASE SEQUENCE; CELL AGING; CELL DIVISION; CELL LINE; CELL LINE, TRANSFORMED; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; LYMPHOID TISSUE; MOLECULAR SEQUENCE DATA; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0033151972     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Lenschow, D. J., T. L. Walunas, and J. A. Bluestone. 1996. CD28/B7 system of T cell co-stimulation. Annu. Rev. Immunol. 14:233.
2. Ward, S. G. 1996. CD28: a signaling perspective. Biochem. J. 318:331.
3. Boise, L. H., A. J. Minn, P. J. Noel, C. H. June, M. Accavitti, T. Lindsten, and C. B. Thompson. 1995. CD28 co-stimulation can promote T cell survival by enhancing the expression of Bcl-xL. Immunity 3:87.
4. Thompson, C. B., T. Lindsten, J. A. Ledbetter, S. L. Kunkel, H. A. Young, S. G. Emerson, J. M. Leiden, and C. H. June. 1989. CD28 activation pathway regulates the production of multiple T cell-derived lymphokines/cytokines. Proc. Natl. Acad. Sci. USA 86:1333.
5. McArthur, J. G., and D. H. Raulet. 1993. CD28-induced co-stimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4. J. Exp. Med. 178:1645.
6. Linsley, P. S., and J. A. Ledbetter. 1993. The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol. 11:191.
7. Harding, F. A., J. G. MacArthur, J. A. Gross, D. H. Raulet, and J. P. Allison. 1992. CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356:607.
8. Shahinian, A., K. Pfeffer, K. P. Lee, T. M. Kundig, K. Kishihara, A. Wakeham, K. Kawai, P. S. Ohashi, C. B. Thompson, and T. W. Mak. 1993. Differential T cell co-stimulatory requirements in CD28-deficient mice. Science 261:609.
9. Carry, D. B., S. L. Reiner, P. S. Linsley, and R. M. Locksley. 1994. Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis. J. Immunol. 153:4142.
10. Boise, L. H., P. J. Noel, and C. B. Thompson. 1995. CD28 and apoptosis. Curr. Opin. Immunol. 7:620.
11. + T cells is associated with the loss of gene-specific nuclear factor binding activity. J. Biol. Chem. 273:8119.
12. - T cells are expanded in rheumatoid arthritis and are characterized by auto-reactivity. J. Clin. Invest. 97:2027.
13. Eck, S. C., D. Chang, A. D. Wells, and L. A. Turka. 1997. Differential down-regulation of CD28 by B7-1 and B7-2 engagement. Transplantation 64:1497.
14. + T cells in centenarians and in long term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence. Exp. Gerontol. 29:601.
15. Effros, R. B. 1997. Loss of CD28 expression on T lymphocytes: a marker of replicative senescence. Dev. Comp. Immunol. 21:471.
16. Linsley, P. S., J. Ledbetter, R. Peach, and J. Bajorath. 1995. CD28/CTLA-4 receptor structure, binding stoichiometry and aggregation during T-cell activation. Res. Immunol. 146:130.
17. Kariv, I., A. Truneh, and R. W. Sweet. 1996. Analysis of the site of interaction of CD28 with its counter-receptors CD80 and CD86 and correlation with function. J. Immunol. 157:29.
18. Linsley, P. S., J. L. Greene, W. Brady, J. Bajorath, J. A. Ledbetter, and R. Peach. 1994. Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors. Immunity 1:793.
19. Greene, J. L., G. M. Leytze, J. Emswiler, R. Peach, J. Bajorath, W. Cosand, and P. S. Linsley. 1996. Covalent dimerization of CD28/CTLA-4 and oligomerization of CD80/CD86 regulate T cell co-stimulatory interactions. J. Biol. Chem. 271: 26762.
20. van der Merwe, P. A., D. L. Bodian, S. Daenke, P. Linsley, and S. J. Davis. 1997. CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics. J. Exp. Med. 185:393.
21. + T cells in rheumatoid arthritis. J. Clin. Invest. 94:2068.
22. - T cells. Eur. J. Immunol. 27:1082.
23. - T cells in the aging immune system. Mech. Ageing Dev. 102:131.
24. - T cells from rheumatoid arthritis patients. J. Immunol. 161:1018.
25. Jelinek, D. F., G. J. Ahmann, P. R. Greipp, S. M. Jalal, J. J. Westendorf, J. A. Katzmann, R. A. Kyle, and J. A. Lust. 1993. Coexistence of aneuploid subclones within a multiple myeloma cell line that exhibits clonal immunoglobulin gene rearrangement: clinical implications. Cancer Res. 53:5320.
26. Westendorf, J. J., G. J. Ahmann, P. R. Greipp, T. E. Witzig, R. A. Kyle, J. A. Lust, and D. F. Jelinek. 1996. Establishment and characterization of three myeloma cell lines that demonstrate variable cytokine responses and abilities to produce autocrine interleukin-6. Leukemia 10:866.
27. Vallejo, A. N., and L. R. Pease. 1995. Structure of the MHC A and B locus promoters in hominoids: insights on the evolution of the class I MHC multigene family. J. Immunol. 154:3912.
28. Aruffo, A., and B. Seed. 1987. Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc. Natl. Acad. Sci. USA 84:8573.
29. Lee, K. P., C. Taylor, B. Petryniak, L. A. Turka, C. H. June, and C. B. Thompson. 1990. The genomic organization of the CD28 gene: implications for the regulation of CD28 mRNA expression and heterogeneity. J. Immunol. 145:344.
30. Vallejo, A. N., and L. R. Pease. 1996. The locus-specific enhancer activity of the class I major histocompatibility complex interferon-responsive element is associated with a γ-interferon (IFN)-inducible factor distinct from STAT1α, p48, and IFN regulatory factor-1. J. Biol. Chem. 271:29813.
31. Brunn, G. J., E. L. Falls, A. E. Nilson, and R. T. Abraham. 1995. Protein-tyrosine kinase-dependem activation of STAT transcription factors in interleukin-2-or interleukin-4-stimulated T lymphocytes. J. Biol. Chem. 270:11628.
32. - T cells in healthy ageing people including centenarians. Immunology 88:501.
33. - cells with ageing. Clin. Exp. Immunol. 112:48.
34. + T cell apoptosis in patients with acute herpesvirus infections: loss of co-stimulatory molecules CD28, CDS and CD6 but relative maintenance of Bax and Bcl-x expression. Immunology 88:508.
35. + T lymphocyte compartment. Transplantation 63:693.
36. + lymphocyte homeostasis during the natural course of HIV-1 infection. J. Clin. Invest. 101:137.
37. Posnett, D. N., R. Sinha, S. Kabak, and C. Russo. 1994. Clonal populations of T cells in normal elderly humans: The T cell equivalent to "benign monoclonal gammopathy." J. Exp. Med. 179:609.
38. + T cells in health and disease: aging, infection, or immune regulation? Hum. Immunol. 48:68.
39. Dutra, W. O., O. A. Martins-Filho, J. R. Cancado, J. C. Pinto-Dias, Z. Brener, G. Gazzinelli, J. F. Carvalho, and D. G. Colley. 1996. Chagasic patients lack CD28 expression on many of their circulating T lymphocytes. Scand. J. Immunol. 43:88.
40. - T cell expansion: anergy or activation? Clin. Exp. Immunol. 104:180.
41. Garcia-Alonso, A. M., A. Minguela, M. Muro, J. Ontanon, A. Torio, L. Marin, P. Lopez-Segura, M. Miras, and M. R. Alvarez-Lopez. 1997. CD28 expression on peripheral blood T lymphocytes after orthotopic liver transplant: upregulation in acute rejection. Hum. Immunol. 53:64.
42. Turka, L. A., J. A. Ledbetter, K. Lee, C. H. June, and C. B. Thompson. 1990. CD28 is an inducible T cell surface antigen that transduces a proliferative signal in CD3+ mature thymocytes. J. Immunol. 144:1646.
43. + T cells from HIV-infected subjects. Clin. Exp. Immunol. 100:425.
44. + T cells. J. Immunol. 158:1551.
45. Walker, L. S., J. D. McLeod, G. Boulougouris, Y. I. Patel, N. D. Hall, and D. M. Sansom. 1998. Down-regulation of CD28 via Fas (CD95): influence of CD28 on T cell apoptosis. Immunology 94:41.
46. Pellat-Deceunynck, C., R. Bataille, N. Robillard, J. L. Harousseau, M. J. Rapp, N. Juge-Morineau, J. Wijdenes, and M. Amiot. 1994. Expression of CD28 and CD40 in human myeloma cells: a comparative study with normal plasma cells. Blood 84:2597.
47. Robillard, N., G. Jego, C. Pellat-Deceunynck, D. Pineau, D. Puthier, M. P. Mellerin, S. Barille, M. J. Rapp, J. L. Harousseau, M. Amiot, and R. Bataille. 1998. CD28, a marker associated with tumor expansion in multiple myeloma. Clin. Cancer Res. 4:1521.
48. Epstein, J., R. Hoover, J. Kornbluth, and B. Barlogie. 1995. Biological aspects of multiple myeloma. Baillieres Clin. Haematol. 8:721.
49. Zhang, X. G., D. Olive, J. Devos, C. Rebouissou, M. Ghiotto-Ragueneau, M. Ferlin, and B. Klein. 1998. Malignant plasma cell lines express a functional CD28 molecule. Leukemia 12:610.
50. Weyand, C. M., J. J. Goronzy, and G. Fathman. 1987. Modulation of CD4 by antigenic activation. J. Immunol. 138:1351.
51. lck, increased association with clathrin-coated pits, and altered endosomal sorting. J. Exp. Med. 178:1209.
52. + T cells. J. Exp. Med. 185:641.
53. Viola, A., M. Saito, L. Tuosto, S. Linkert, O. Acuto, and A. Lanzavecchia. 1997. Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering. J. Exp. Med. 186:1775.
54. Lauritsen, J. P., M. D. Christen, J. Dietrich, J. Kastrup, N. Odum, and C. Geisler. 1998. Two distinct pathways exist for down-regulation of the TCR. J. Immunol. 161:260.
55. Pawelec, G., A. Rehbein, K. Haehnel, A. Merl, and M. Adibzadeh. 1997. Human T cell clones in long term culture as a model of immunosenescence. Immunol. Rev. 160:31.
56. + counterparts. J. Immunol. 156:3587.
57. - T cells in rheumatoid arthritis. Mol. Med. 2:608.
58. Waase, I., C. Kayser, P. J. Carlson, J. J. Goronzy, and C. M. Weyand. 1996. Oligoclonal T cell proliferation in patients with rheumatoid arthritis and their unaffected siblings. Arthritis Rheum. 39:904.
59. + T cells in severe rheumatoid arthritis. Arthritis Rheum. 40:1106.