Antiviral therapy can reverse the development of immune senescence in elderly mice with latent cytomegalovirus infection

Journal of Virology

Volumn 87, Issue 2, 2013, Pages 779-789

  Beswick, Mark ^a   Annette, Pachnio ^a   Lauder, Sarah N ^a   Clive, Sweet ^a   Moss, Paul A ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

VALACICLOVIR;

ADAPTIVE IMMUNITY; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL THERAPY; ARTICLE; CD8+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; CYTOTOXIC LYMPHOCYTE; EMBRYO; EXPERIMENTAL MOUSE; FEMALE; HUMORAL IMMUNITY; IMMUNOGENICITY; INFLUENZA VIRUS A; LYMPHOCYTE DIFFERENTIATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SENESCENCE; T LYMPHOCYTE ACTIVATION; VIRUS IMMUNITY; VIRUS LOAD; VIRUS REACTIVATION; VIRUS REPLICATION;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; CD8-POSITIVE T-LYMPHOCYTES; CYTOMEGALOVIRUS INFECTIONS; FEMALE; IMMUNOLOGIC MEMORY; MICE; MICE, INBRED C57BL; MUROMEGALOVIRUS; VALINE; VIRUS ACTIVATION; VIRUS LATENCY;

ANIMALIA; CYTOMEGALOVIRUS; MAIZE CHLOROTIC MOTTLE VIRUS; MURINAE; MUS; ORTHOMYXOVIRIDAE;

EID: 84871998933     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02427-12     Document Type: Article

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