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Volumn 109, Issue 4, 2007, Pages 1756-1764

Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 33846910425     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-08-042853     Document Type: Article
Times cited : (130)

References (65)
  • 1
    • 0018777790 scopus 로고
    • Chronic graft versus host disease: A syndrome of disordered immunity
    • Graze PR, Gale RP. Chronic graft versus host disease: a syndrome of disordered immunity. Am J Med. 1979;66:611-620.
    • (1979) Am J Med , vol.66 , pp. 611-620
    • Graze, P.R.1    Gale, R.P.2
  • 2
    • 0018973048 scopus 로고
    • Chronic graft-versus-host syndrome in man: A long-term clinicopathologic study of 20 Seattle patients
    • Shulman HM, Sullivan KM, Weiden PL, et al. Chronic graft-versus-host syndrome in man: a long-term clinicopathologic study of 20 Seattle patients. Am J Med. 1980;69:204-217.
    • (1980) Am J Med , vol.69 , pp. 204-217
    • Shulman, H.M.1    Sullivan, K.M.2    Weiden, P.L.3
  • 3
    • 0033168009 scopus 로고    scopus 로고
    • Long-term survival and late deaths after allogeneic bone marrow transplantation. Late Effects Working Committee of the International Bone Marrow Transplant Registry
    • Socie G, Stone JV, Wingard JR, et al. Long-term survival and late deaths after allogeneic bone marrow transplantation. Late Effects Working Committee of the International Bone Marrow Transplant Registry. N Engl J Med. 1999;341:14-21.
    • (1999) N Engl J Med , vol.341 , pp. 14-21
    • Socie, G.1    Stone, J.V.2    Wingard, J.R.3
  • 4
    • 4444294637 scopus 로고    scopus 로고
    • Late effects in survivors of chronic myeloid leukemia treated with hematopoietic cell transplantation: Results from the Bone Marrow Transplant Survivor Study
    • Baker KS, Gurney JG, Ness KK, et al. Late effects in survivors of chronic myeloid leukemia treated with hematopoietic cell transplantation: results from the Bone Marrow Transplant Survivor Study. Blood. 2004;104:1898-1906.
    • (2004) Blood , vol.104 , pp. 1898-1906
    • Baker, K.S.1    Gurney, J.G.2    Ness, K.K.3
  • 5
    • 0030914537 scopus 로고    scopus 로고
    • Cyclosporine or cyclosporine plus methylprednisolone for prophylaxis of graft-versus-host disease: A prospective, randomized trial
    • Deeg HJ, Lin D, Leisenring W, Boeckh M, Anasetti C. Cyclosporine or cyclosporine plus methylprednisolone for prophylaxis of graft-versus-host disease: a prospective, randomized trial. Blood. 1997;89:3880-3887.
    • (1997) Blood , vol.89 , pp. 3880-3887
    • Deeg, H.J.1    Lin, D.2    Leisenring, W.3    Boeckh, M.4    Anasetti, C.5
  • 6
    • 0024459937 scopus 로고
    • Graft-versus-host disease prevention by methotrexate combined with cyclosporin compared to methotrexate alone in patients given marrow grafts for severe aplastic anaemia: Long-term follow-up of a controlled trial
    • Storb R, Deeg HJ, Pepe M, et al. Graft-versus-host disease prevention by methotrexate combined with cyclosporin compared to methotrexate alone in patients given marrow grafts for severe aplastic anaemia: long-term follow-up of a controlled trial. Br J Haematol. 1989;72:567-572.
    • (1989) Br J Haematol , vol.72 , pp. 567-572
    • Storb, R.1    Deeg, H.J.2    Pepe, M.3
  • 7
    • 0035895103 scopus 로고    scopus 로고
    • Administration of cyclosporine for 24 months compared with 6 months for prevention of chronic graft-versus-host disease: A prospective randomized clinical trial
    • Kansu E, Gooley T, Flowers ME, et al. Administration of cyclosporine for 24 months compared with 6 months for prevention of chronic graft-versus-host disease: a prospective randomized clinical trial. Blood. 2001;98:3868-3870.
    • (2001) Blood , vol.98 , pp. 3868-3870
    • Kansu, E.1    Gooley, T.2    Flowers, M.E.3
  • 8
    • 0030133625 scopus 로고    scopus 로고
    • Paradoxical effect of thalidomide prophylaxis on chronic graft-vs.-host disease
    • Chao NJ, Parker PM, Niland JC, et al. Paradoxical effect of thalidomide prophylaxis on chronic graft-vs.-host disease. Biol Blood Marrow Transplant. 1996;2:86-92.
    • (1996) Biol Blood Marrow Transplant , vol.2 , pp. 86-92
    • Chao, N.J.1    Parker, P.M.2    Niland, J.C.3
  • 9
    • 0024510510 scopus 로고
    • Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: Long-term follow-up of a controlled trial
    • Storb R, Deeg HJ, Pepe M, et al. Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial. Blood. 1989;73:1729-1734.
    • (1989) Blood , vol.73 , pp. 1729-1734
    • Storb, R.1    Deeg, H.J.2    Pepe, M.3
  • 10
    • 0032188990 scopus 로고    scopus 로고
    • Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation
    • Ratanatharathorn V, Nash RA, Przepiorka D, et al. Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation. Blood. 1998;92:2303-2314.
    • (1998) Blood , vol.92 , pp. 2303-2314
    • Ratanatharathorn, V.1    Nash, R.A.2    Przepiorka, D.3
  • 11
    • 0023879179 scopus 로고
    • T-cell interactions in autoimmunity: Insights from a murine model of graft-versus-host disease
    • Via CS, Shearer GM. T-cell interactions in autoimmunity: insights from a murine model of graft-versus-host disease. Immunol Today. 1988;9:207-213.
    • (1988) Immunol Today , vol.9 , pp. 207-213
    • Via, C.S.1    Shearer, G.M.2
  • 12
    • 0020082244 scopus 로고
    • A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation: Preferential formation of autoantibodies characteristic of SLE
    • Gleichmann E, Van Elven EH, Van der Veen JP. A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation: preferential formation of autoantibodies characteristic of SLE. Eur J Immunol. 1982;12:152-159.
    • (1982) Eur J Immunol , vol.12 , pp. 152-159
    • Gleichmann, E.1    Van Elven, E.H.2    Van der Veen, J.P.3
  • 13
    • 0021279032 scopus 로고
    • Further evidence against random polyclonal antibody formation in mice with lupus-like graft-vs-host disease
    • van Rappard-Van der Veen FM, Kiesel U, Poels L, et al. Further evidence against random polyclonal antibody formation in mice with lupus-like graft-vs-host disease. J Immunol. 1984;132:1814-1820.
    • (1984) J Immunol , vol.132 , pp. 1814-1820
    • van Rappard-Van der Veen, F.M.1    Kiesel, U.2    Poels, L.3
  • 14
    • 0020630583 scopus 로고
    • Chronic graft-versus-host disease (GVHD) as a model for scleroderma: I. Description of model systems
    • Jaffee BD, Claman HN. Chronic graft-versus-host disease (GVHD) as a model for scleroderma: I. Description of model systems. Cell Immunol. 1983;77:1-12.
    • (1983) Cell Immunol , vol.77 , pp. 1-12
    • Jaffee, B.D.1    Claman, H.N.2
  • 16
    • 33645505721 scopus 로고    scopus 로고
    • Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations
    • Zhang C, Todorov I, Zhang Z, et al. Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations. Blood. 2006;107:2993-3001.
    • (2006) Blood , vol.107 , pp. 2993-3001
    • Zhang, C.1    Todorov, I.2    Zhang, Z.3
  • 17
    • 0030801512 scopus 로고    scopus 로고
    • Pathways of T-cell regeneration in mice and humans: Implications for bone marrow transplantation and immunotherapy
    • Mackall CL, Gress RE. Pathways of T-cell regeneration in mice and humans: implications for bone marrow transplantation and immunotherapy. Immunol Rev. 1997;157:61-72.
    • (1997) Immunol Rev , vol.157 , pp. 61-72
    • Mackall, C.L.1    Gress, R.E.2
  • 18
    • 0035760863 scopus 로고    scopus 로고
    • The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation
    • Ho VT, Soiffer RJ. The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation. Blood. 2001;98:3192-3204.
    • (2001) Blood , vol.98 , pp. 3192-3204
    • Ho, V.T.1    Soiffer, R.J.2
  • 19
    • 0018257740 scopus 로고
    • Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice: Prevention by removing mature T-cells from marrow
    • Korngold R, Sprent J. Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice: prevention by removing mature T-cells from marrow. J Exp Med. 1978;148:1687-1698.
    • (1978) J Exp Med , vol.148 , pp. 1687-1698
    • Korngold, R.1    Sprent, J.2
  • 20
    • 0024460223 scopus 로고
    • Graft-versus-host disease: An alternative hypothesis
    • Parkman R. Graft-versus-host disease: an alternative hypothesis. Immunol Today. 1989;10:362-364.
    • (1989) Immunol Today , vol.10 , pp. 362-364
    • Parkman, R.1
  • 21
    • 0025041895 scopus 로고
    • Thymus: A direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self-tolerance
    • Fukushi N, Arase H, Wang B, et al. Thymus: a direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self-tolerance. Proc Natl Acad Sci U S A. 1990;87:6301-6305.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 6301-6305
    • Fukushi, N.1    Arase, H.2    Wang, B.3
  • 22
    • 0023683518 scopus 로고
    • Complete sequential regeneration of graft-vs.-host-induced severely dysplastic thymuses: Implications for the pathogenesis of chronic graft-vs.-host disease
    • Ghayur T, Seemayer TA, Xenocostas A, Lapp WS. Complete sequential regeneration of graft-vs.-host-induced severely dysplastic thymuses: implications for the pathogenesis of chronic graft-vs.-host disease. Am J Pathol. 1988;133:39-46.
    • (1988) Am J Pathol , vol.133 , pp. 39-46
    • Ghayur, T.1    Seemayer, T.A.2    Xenocostas, A.3    Lapp, W.S.4
  • 23
    • 27644515599 scopus 로고    scopus 로고
    • Influence of T-cell depletion on chronic graft-versus-host disease: Results of a multicenter randomized trial in unrelated marrow donor transplantation
    • Pavletic SZ, Carter SL, Kernan NA, et al. Influence of T-cell depletion on chronic graft-versus-host disease: results of a multicenter randomized trial in unrelated marrow donor transplantation. Blood. 2005;106:3308-3313.
    • (2005) Blood , vol.106 , pp. 3308-3313
    • Pavletic, S.Z.1    Carter, S.L.2    Kernan, N.A.3
  • 24
    • 0033491636 scopus 로고    scopus 로고
    • T lymphocyte tolerance: From thymic deletion to peripheral control mechanisms
    • Stockinger B. T lymphocyte tolerance: from thymic deletion to peripheral control mechanisms. Adv Immunol. 1999;71:229-265.
    • (1999) Adv Immunol , vol.71 , pp. 229-265
    • Stockinger, B.1
  • 25
    • 0037105537 scopus 로고    scopus 로고
    • Direct evidence for new T-cell generation by patients after either T-cell-depleted or unmodified allogeneic hematopoietic stem cell transplantations
    • Lewin SR, Heller G, Zhang L, et al. Direct evidence for new T-cell generation by patients after either T-cell-depleted or unmodified allogeneic hematopoietic stem cell transplantations. Blood. 2002;100:2235-2242.
    • (2002) Blood , vol.100 , pp. 2235-2242
    • Lewin, S.R.1    Heller, G.2    Zhang, L.3
  • 26
    • 0034720664 scopus 로고    scopus 로고
    • Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T-cell reconstitution
    • Douek DC, Vescio RA, Betts MR, et al. Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T-cell reconstitution. Lancet. 2000;355:1875-1881.
    • (2000) Lancet , vol.355 , pp. 1875-1881
    • Douek, D.C.1    Vescio, R.A.2    Betts, M.R.3
  • 27
    • 0035282934 scopus 로고    scopus 로고
    • Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation
    • Weinberg K, Blazar BR, Wagner JE, et al. Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation. Blood. 2001;97:1458-1466.
    • (2001) Blood , vol.97 , pp. 1458-1466
    • Weinberg, K.1    Blazar, B.R.2    Wagner, J.E.3
  • 28
    • 0027323989 scopus 로고
    • Thymic selection and thymic major histocompatibility complex class II expression are abnormal in mice undergoing graft-versus-host reactions
    • Desbarats J, Lapp WS. Thymic selection and thymic major histocompatibility complex class II expression are abnormal in mice undergoing graft-versus-host reactions. J Exp Med. 1993;178:805-814.
    • (1993) J Exp Med , vol.178 , pp. 805-814
    • Desbarats, J.1    Lapp, W.S.2
  • 29
    • 0033998917 scopus 로고    scopus 로고
    • Graft-versus-host- disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity
    • van den Brink MR, Moore E, Ferrara JL, Burakoff SJ. Graft-versus-host- disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity. Transplantation. 2000;69:446-449.
    • (2000) Transplantation , vol.69 , pp. 446-449
    • van den Brink, M.R.1    Moore, E.2    Ferrara, J.L.3    Burakoff, S.J.4
  • 30
    • 0028294132 scopus 로고
    • Loss of normal thymic repertoire selection and persistence of autoreactive T cells in graft vs. host disease
    • Hollander GA, Widmer B, Burakoff SJ. Loss of normal thymic repertoire selection and persistence of autoreactive T cells in graft vs. host disease. J Immunol. 1994;152:1609-1617.
    • (1994) J Immunol , vol.152 , pp. 1609-1617
    • Hollander, G.A.1    Widmer, B.2    Burakoff, S.J.3
  • 31
    • 16644379996 scopus 로고    scopus 로고
    • Higher mortality after allogeneic peripheral-blood transplantation compared with bone marrow in children and adolescents: The Histocompatibility and Alternate Stem Cell Source Working Committee of the International Bone Marrow Transplant Registry
    • Eapen M, Horowitz MM, Klein JP, et al. Higher mortality after allogeneic peripheral-blood transplantation compared with bone marrow in children and adolescents: the Histocompatibility and Alternate Stem Cell Source Working Committee of the International Bone Marrow Transplant Registry. J Clin Oncol. 2004;22:4872-4880.
    • (2004) J Clin Oncol , vol.22 , pp. 4872-4880
    • Eapen, M.1    Horowitz, M.M.2    Klein, J.P.3
  • 32
    • 0037818713 scopus 로고    scopus 로고
    • Impaired thymic negative selection causes autoimmune graft-versus-host disease
    • Teshima T, Reddy P, Liu C, Williams D, Cooke KR, Ferrara JL. Impaired thymic negative selection causes autoimmune graft-versus-host disease. Blood. 2003;102:429-435.
    • (2003) Blood , vol.102 , pp. 429-435
    • Teshima, T.1    Reddy, P.2    Liu, C.3    Williams, D.4    Cooke, K.R.5    Ferrara, J.L.6
  • 33
    • 0026044013 scopus 로고
    • Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice
    • Grusby MJ, Johnson RS, Papaioannou VE, Glimcher LH. Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice. Science. 1991;253:1417-1420.
    • (1991) Science , vol.253 , pp. 1417-1420
    • Grusby, M.J.1    Johnson, R.S.2    Papaioannou, V.E.3    Glimcher, L.H.4
  • 34
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
    • Onizuka S, Tawara I, Shimizu J, Sakaguchi S, Fujita T, Nakayama E. Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res. 1999;59:3128-3133.
    • (1999) Cancer Res , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 35
    • 0029909099 scopus 로고    scopus 로고
    • An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin
    • Cooke KR, Kobzik L, Martin TR, et al. An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin. Blood. 1996;88:3230-3239.
    • (1996) Blood , vol.88 , pp. 3230-3239
    • Cooke, K.R.1    Kobzik, L.2    Martin, T.R.3
  • 37
    • 0036281797 scopus 로고    scopus 로고
    • Acute graft-versus-host disease does not require alloantigen expression on host epithelium
    • Teshima T, Ordemann R, Reddy P, et al. Acute graft-versus-host disease does not require alloantigen expression on host epithelium. Nat Med. 2002;8:575-581.
    • (2002) Nat Med , vol.8 , pp. 575-581
    • Teshima, T.1    Ordemann, R.2    Reddy, P.3
  • 38
    • 0036493605 scopus 로고    scopus 로고
    • Flt3 ligand therapy for recipients of allogeneic bone marrow transplants expands host CD8 alpha(+) dendritic cells and reduces experimental acute graft-versus-host disease
    • Teshima T, Reddy P, Lowler KP, et al. Flt3 ligand therapy for recipients of allogeneic bone marrow transplants expands host CD8 alpha(+) dendritic cells and reduces experimental acute graft-versus-host disease. Blood. 2002;99:1825-1832.
    • (2002) Blood , vol.99 , pp. 1825-1832
    • Teshima, T.1    Reddy, P.2    Lowler, K.P.3
  • 39
    • 30144445540 scopus 로고    scopus 로고
    • Fetal tolerance to maternal antigens improves the outcome of allogeneic bone marrow transplantation by a CD4+ CD25+ T-cell-dependent mechanism
    • Matsuoka K, Ichinohe T, Hashimoto D, Asakura S, Tanimoto M, Teshima T. Fetal tolerance to maternal antigens improves the outcome of allogeneic bone marrow transplantation by a CD4+ CD25+ T-cell-dependent mechanism. Blood. 2006;107:404-409.
    • (2006) Blood , vol.107 , pp. 404-409
    • Matsuoka, K.1    Ichinohe, T.2    Hashimoto, D.3    Asakura, S.4    Tanimoto, M.5    Teshima, T.6
  • 40
    • 10844271455 scopus 로고    scopus 로고
    • Stimulation of host NKT cells by synthetic glycolipid regulates acute graft-versus-host disease by inducing Th2 polarization of donor T cells
    • Hashimoto D, Asakura S, Miyake S, et al. Stimulation of host NKT cells by synthetic glycolipid regulates acute graft-versus-host disease by inducing Th2 polarization of donor T cells. J Immunol. 2005;174:551-556.
    • (2005) J Immunol , vol.174 , pp. 551-556
    • Hashimoto, D.1    Asakura, S.2    Miyake, S.3
  • 42
    • 29844442863 scopus 로고    scopus 로고
    • Histopathologic diagnosis of chronic graft-versus-host disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: II. Pathology Working Group Report
    • Shulman HM, Kleiner D, Lee SJ, et al. Histopathologic diagnosis of chronic graft-versus-host disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: II. Pathology Working Group Report. Biol Blood Marrow Transplant. 2006;12:31-47.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 31-47
    • Shulman, H.M.1    Kleiner, D.2    Lee, S.J.3
  • 43
    • 28744444180 scopus 로고    scopus 로고
    • National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report
    • Filipovich AH, Weisdorf D, Pavletic S, et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report. Biol Blood Marrow Transplant. 2005;11:945-956.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 945-956
    • Filipovich, A.H.1    Weisdorf, D.2    Pavletic, S.3
  • 44
    • 0035139040 scopus 로고    scopus 로고
    • Tumor cell vaccine elicits potent antitumor immunity after allogeneic T-cell-depleted bone marrow transplantation
    • Teshima T, Mach N, Hill GR, et al. Tumor cell vaccine elicits potent antitumor immunity after allogeneic T-cell-depleted bone marrow transplantation. Cancer Res. 2001;61:162-171.
    • (2001) Cancer Res , vol.61 , pp. 162-171
    • Teshima, T.1    Mach, N.2    Hill, G.R.3
  • 45
    • 14944370670 scopus 로고    scopus 로고
    • Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: Requirements depend on target organ
    • Anderson BE, McNiff JM, Jain D, Blazar BR, Shlomchik WD, Shlomchik MJ. Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ. Blood. 2005;105:2227-2234.
    • (2005) Blood , vol.105 , pp. 2227-2234
    • Anderson, B.E.1    McNiff, J.M.2    Jain, D.3    Blazar, B.R.4    Shlomchik, W.D.5    Shlomchik, M.J.6
  • 46
    • 20144371067 scopus 로고    scopus 로고
    • Prognostic value of pretransplantation host thymic function in HLA-identical sibling hematopoietic stem cell transplantation
    • Clave E, Rocha V, Talvensaari K, et al. Prognostic value of pretransplantation host thymic function in HLA-identical sibling hematopoietic stem cell transplantation. Blood. 2005;105:2608-2613.
    • (2005) Blood , vol.105 , pp. 2608-2613
    • Clave, E.1    Rocha, V.2    Talvensaari, K.3
  • 47
    • 0025006543 scopus 로고
    • Effector mechanisms in cyclosporine A-induced syngeneic graft-versus-host disease: Role of CD4+ and CD8+ T lymphocyte subsets
    • Hess AD, Fischer AC, Beschorner WE. Effector mechanisms in cyclosporine A-induced syngeneic graft-versus-host disease: role of CD4+ and CD8+ T lymphocyte subsets. J Immunol. 1990;145:526-533.
    • (1990) J Immunol , vol.145 , pp. 526-533
    • Hess, A.D.1    Fischer, A.C.2    Beschorner, W.E.3
  • 48
    • 30344487288 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells and graft-versus-host disease
    • Hoffmann P, Edinger M. CD4+CD25+ regulatory T cells and graft-versus-host disease. Semin Hematol. 2006;43:62-69.
    • (2006) Semin Hematol , vol.43 , pp. 62-69
    • Hoffmann, P.1    Edinger, M.2
  • 49
    • 22244462396 scopus 로고    scopus 로고
    • Regulatory T cells in immunologic self-tolerance and autoimmune disease
    • Sakaguchi S, Sakaguchi N. Regulatory T cells in immunologic self-tolerance and autoimmune disease. Int Rev Immunol. 2005;24:211-226.
    • (2005) Int Rev Immunol , vol.24 , pp. 211-226
    • Sakaguchi, S.1    Sakaguchi, N.2
  • 50
    • 0035920510 scopus 로고    scopus 로고
    • Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells
    • Bensinger SJ, Bandeira A, Jordan MS, Caton AJ, Laufer TM. Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells. J Exp Med. 2001;194:427-438.
    • (2001) J Exp Med , vol.194 , pp. 427-438
    • Bensinger, S.J.1    Bandeira, A.2    Jordan, M.S.3    Caton, A.J.4    Laufer, T.M.5
  • 51
    • 33646882230 scopus 로고    scopus 로고
    • Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance
    • Shimoda M, Mmanywa F, Joshi SK, et al. Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance. J Immunol. 2006;176:6503-6511.
    • (2006) J Immunol , vol.176 , pp. 6503-6511
    • Shimoda, M.1    Mmanywa, F.2    Joshi, S.K.3
  • 53
    • 0023242018 scopus 로고
    • L3T4-positive T cells participate in the induction of graft-vs-host disease in response to minor histocompatibility antigens
    • Hamilton BL. L3T4-positive T cells participate in the induction of graft-vs-host disease in response to minor histocompatibility antigens. J Immunol. 1987;139:2511-2515.
    • (1987) J Immunol , vol.139 , pp. 2511-2515
    • Hamilton, B.L.1
  • 54
    • 20444362731 scopus 로고    scopus 로고
    • Emergent autoimmunity in graft-versus-host disease
    • Tivol E, Komorowski R, Drobyski WR. Emergent autoimmunity in graft-versus-host disease. Blood. 2005;105:4885-4891.
    • (2005) Blood , vol.105 , pp. 4885-4891
    • Tivol, E.1    Komorowski, R.2    Drobyski, W.R.3
  • 55
    • 18644365981 scopus 로고    scopus 로고
    • Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: Evidence from a lymphopenic T cell model
    • Bhandoola A, Tai X, Eckhaus M, et al. Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model. Immunity. 2002;17:425-436.
    • (2002) Immunity , vol.17 , pp. 425-436
    • Bhandoola, A.1    Tai, X.2    Eckhaus, M.3
  • 56
    • 0033571072 scopus 로고    scopus 로고
    • Anti-TGF-beta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: A model for human scleroderma
    • McCormick LL, Zhang Y, Tootell E, Gilliam AC. Anti-TGF-beta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: a model for human scleroderma. J Immunol. 1999;163:5693-5699.
    • (1999) J Immunol , vol.163 , pp. 5693-5699
    • McCormick, L.L.1    Zhang, Y.2    Tootell, E.3    Gilliam, A.C.4
  • 57
    • 0033556556 scopus 로고    scopus 로고
    • Serum transforming growth factor-beta1 levels in bone marrow transplant recipients correlate with blood cell counts and chronic graft-versus-host disease
    • Liem LM, Fibbe WE, van Houwelingen HC, Goulmy E. Serum transforming growth factor-beta1 levels in bone marrow transplant recipients correlate with blood cell counts and chronic graft-versus-host disease. Transplantation. 1999;67:59-65.
    • (1999) Transplantation , vol.67 , pp. 59-65
    • Liem, L.M.1    Fibbe, W.E.2    van Houwelingen, H.C.3    Goulmy, E.4
  • 58
    • 0037087318 scopus 로고    scopus 로고
    • Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: Cutaneous cytokines, chemokines, and immune cell activation
    • Zhang Y, McCormick LL, Desai SR, Wu C, Gilliam AC. Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation. J Immunol. 2002;168:3088-3098.
    • (2002) J Immunol , vol.168 , pp. 3088-3098
    • Zhang, Y.1    McCormick, L.L.2    Desai, S.R.3    Wu, C.4    Gilliam, A.C.5
  • 59
    • 24744447794 scopus 로고    scopus 로고
    • TGF-beta in allogeneic stem cell transplantation: Friend or foe?
    • Banovic T, MacDonald KP, Morris ES, et al. TGF-beta in allogeneic stem cell transplantation: friend or foe? Blood. 2005;106:2206-2214.
    • (2005) Blood , vol.106 , pp. 2206-2214
    • Banovic, T.1    MacDonald, K.P.2    Morris, E.S.3
  • 60
    • 20144386800 scopus 로고    scopus 로고
    • Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission
    • Miklos DB, Kim HT, Miller KH, et al. Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission. Blood. 2005;105:2973-2978.
    • (2005) Blood , vol.105 , pp. 2973-2978
    • Miklos, D.B.1    Kim, H.T.2    Miller, K.H.3
  • 61
    • 0033566353 scopus 로고    scopus 로고
    • Massive activation-induced cell death of alloreactive T cells with apoptosis of bystander postthymic T cells prevents immune reconstitution in mice with graft-versus-host disease
    • Brochu S, Rioux-Masse B, Roy J, Roy DC, Perreault C. Massive activation-induced cell death of alloreactive T cells with apoptosis of bystander postthymic T cells prevents immune reconstitution in mice with graft-versus-host disease. Blood. 1999;94:390-400.
    • (1999) Blood , vol.94 , pp. 390-400
    • Brochu, S.1    Rioux-Masse, B.2    Roy, J.3    Roy, D.C.4    Perreault, C.5
  • 62
    • 0038494591 scopus 로고    scopus 로고
    • Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays
    • Ichiba T, Teshima T, Kuick R, et al. Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays. Blood. 2003;102:763-771.
    • (2003) Blood , vol.102 , pp. 763-771
    • Ichiba, T.1    Teshima, T.2    Kuick, R.3
  • 63
    • 0029835390 scopus 로고    scopus 로고
    • Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
    • Laufer TM, DeKoning J, Markowitz JS, Lo D, Glimcher LH. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature. 1996;383:81-85.
    • (1996) Nature , vol.383 , pp. 81-85
    • Laufer, T.M.1    DeKoning, J.2    Markowitz, J.S.3    Lo, D.4    Glimcher, L.H.5
  • 64
    • 0033136289 scopus 로고    scopus 로고
    • Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo
    • Laufer TM, Fan L, Glimcher LH. Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo. J Immunol. 1999;162:5078-5084.
    • (1999) J Immunol , vol.162 , pp. 5078-5084
    • Laufer, T.M.1    Fan, L.2    Glimcher, L.H.3
  • 65
    • 0022591006 scopus 로고
    • Clonal analysis of murine graft-vs.-host disease: I. Phenotype and functional analysis of T lymphocyte clones
    • Parkman R. Clonal analysis of murine graft-vs.-host disease: I. Phenotype and functional analysis of T lymphocyte clones. J Immunol. 1986;136:3543-3548.
    • (1986) J Immunol , vol.136 , pp. 3543-3548
    • Parkman, R.1


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