Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4 + T cells that mediate autoimmune-like chronic Graft-versus-Host disease

Journal of Immunology

Volumn 189, Issue 1, 2012, Pages 222-233

  Young, James S ^a,b   Wu, Tao ^b,c   Chen, Yuhong ^b,d   Zhao, Dongchang ^b   Liu, Hongjun ^b   Yi, Tangsheng ^a,b   Johnston, Heather ^a,b   Racine, Jeremy ^a,b   Li, Xiaofan ^b,e   Wang, Audrey ^f   Todorov, Ivan ^b   Zeng, Defu ^a,b  

^a Irell and Manella Graduate School of Biological Sciences   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^e FUJIAN MEDICAL UNIVERSITY   (China)

^f City of Hope   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 7 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL EXPANSION; CELL SELECTION; CHRONIC GRAFT VERSUS HOST DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; FLOW CYTOMETRY; GRAFT RECIPIENT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOPATHOLOGY; LUNG; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SALIVARY GLAND; SKIN; SPLEEN; SURVIVAL; TISSUE INJURY;

ANIMALS; AUTOANTIBODIES; B-LYMPHOCYTE SUBSETS; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC DISEASE; CLONE CELLS; DISEASE MODELS, ANIMAL; GRAFT VS HOST DISEASE; LUNG; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; MICE, KNOCKOUT; MICE, TRANSGENIC; SALIVARY GLANDS; SKIN; UP-REGULATION;

EID: 84862888262     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200677     Document Type: Article

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