Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells

Journal of Immunology

Volumn 191, Issue 1, 2013, Pages 488-499

  Wu, Tao ^a,b   Young, James S ^a,c   Johnston, Heather ^a,c   Ni, Xiong ^a,b   Deng, Ruishu ^a   Racine, Jeremy ^a,c   Wang, Miao ^a   Wang, Audrey ^d   Todorov, Ivan ^a   Wang, Jianmin ^b   Zeng, Defu ^a,c  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c Irell and Manella Graduate School of Biological Sciences   (United States)

^d City of Hope   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC GRAFT VERSUS HOST DISEASE; CONTROLLED STUDY; DIARRHEA; EPITHELIUM CELL; HAIR LOSS; HLA MATCHING; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SALIVARY GLAND; SKIN FIBROSIS; SURVIVAL; THYMUS; TISSUE INJURY;

ACUTE DISEASE; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; THYMUS GLAND;

EID: 84879621050     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300657     Document Type: Article

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