Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects

Blood

Volumn 126, Issue 13, 2015, Pages 1609-1620

  Gartlan, Kate H ^a,b   Markey, Kate A ^a   Varelias, Antiopi ^a,b   Bunting, Mark D ^a   Koyama, Motoko ^a   Kuns, Rachel D ^a   Raffelt, Neil C ^a   Olver, Stuart D ^a   Lineburg, Katie E ^a   Cheong, Melody ^a   Teal, Bianca E ^a   Lor, Mary ^a   Comerford, Iain ^c   Teng, Michele W L ^a   Smyth, Mark J ^a,b   McCluskey, James ^d   Rossjohn, Jamie ^e,f   Stockinger, Brigitta ^g   Boyle, Glen M ^a   Lane, Steven W ^a   Clouston, Andrew D ^h   McColl, Shaun R ^c   MacDonald, Kelli P A ^a   Hill, Geoffrey R ^a,i   more..

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e MONASH UNIVERSITY   (Australia)

^f CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^g NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^h Envoi Specialist Pathologists ^*  (Australia)

ⁱ ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 6; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RORGAMMAT; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; CD8 ANTIGEN;

ACUTE GRAFT VERSUS HOST DISEASE; ALLOGENEIC STEM CELL TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELL FATE; CELL LINEAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; EFFECTOR CELL; FEMALE; GENE DELETION; GENE EXPRESSION; GENETIC ASSOCIATION; GRAFT VERSUS LEUKEMIA EFFECT; INFLAMMATION; INFLAMMATORY CELL; LEUKOCYTE MIGRATION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; T CELL DEPLETION; T LYMPHOCYTE SUBPOPULATION; TC17 CELL; ADVERSE EFFECTS; ANIMAL; BAGG ALBINO MOUSE; BONE MARROW TRANSPLANTATION; C57BL MOUSE; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOLOGY; PATHOLOGY; STEM CELL TRANSPLANTATION; TH17 CELL;

ANIMALS; ANTIGENS, CD8; BONE MARROW TRANSPLANTATION; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; GRAFT VS HOST DISEASE; GRAFT VS LEUKEMIA EFFECT; HUMANS; INTERLEUKIN-17; MICE, INBRED BALB C; MICE, INBRED C57BL; STEM CELL TRANSPLANTATION; TH17 CELLS;

EID: 84942275251     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-01-622662     Document Type: Article

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