-
1
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol. 2005;6:1133-1141.
-
(2005)
Nat Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
-
2
-
-
33646164439
-
Expanding the effector CD4 T-cell repertoire: The Th17 lineage
-
Harrington LE, Mangan PR, Weaver CT. Expanding the effector CD4 T-cell repertoire: the Th17 lineage. Curr Opin Immunol. 2006;18:349-356.
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 349-356
-
-
Harrington, L.E.1
Mangan, P.R.2
Weaver, C.T.3
-
3
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan PR, Harrington LE, O'Quinn DB, et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature. 2006;441: 231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
-
4
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L, Ivanov II, Spolski R, et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol. 2007;8:967-974.
-
(2007)
Nat Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
Ivanov II, S.R.2
-
5
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17-T helper cells
-
Ivanov II, McKenzie BS, Zhou L, et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17-T helper cells. Cell. 2006;126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
-
6
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORalpha and RORgamma
-
Yang XO, Pappu BP, Nurieva R, et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORalpha and RORgamma. Immunity. 2008;28:29-39.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
-
7
-
-
27544490377
-
Interleukin 17-producing CD4-effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17-producing CD4-effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005;6:1123-1132.
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
-
8
-
-
33749318470
-
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
-
Liang SC, Tan XY, Luxenberg DP, et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med. 2006;203: 2271-2279.
-
(2006)
J Exp Med
, vol.203
, pp. 2271-2279
-
-
Liang, S.C.1
Tan, X.Y.2
Luxenberg, D.P.3
-
9
-
-
33947195292
-
IL-17- mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infection
-
Umemura M, Yahagi A, Hamada S, et al. IL-17- mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infection. J Immunol. 2007;178:3786-3796.
-
(2007)
J Immunol
, vol.178
, pp. 3786-3796
-
-
Umemura, M.1
Yahagi, A.2
Hamada, S.3
-
10
-
-
0034807936
-
Interleukin-17 and lung host defense against Klebsiella pneumoniae infection
-
Ye P, Garvey PB, Zhang P, et al. Interleukin-17 and lung host defense against Klebsiella pneumoniae infection. Am J Respir Cell Mol Biol. 2001;25:335-340.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 335-340
-
-
Ye, P.1
Garvey, P.B.2
Zhang, P.3
-
11
-
-
0034541221
-
Microbial lipopeptides induce the production of IL-17 in Th cells
-
Infante-Duarte C, Horton HF, Byrne MC, Kamradt T. Microbial lipopeptides induce the production of IL-17 in Th cells. J Immunol. 2000;165:6107-6115.
-
(2000)
J Immunol
, vol.165
, pp. 6107-6115
-
-
Infante-Duarte, C.1
Horton, H.F.2
Byrne, M.C.3
Kamradt, T.4
-
12
-
-
3242814586
-
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice
-
Huang W, Na L, Fidel PL, Schwarzenberger P. Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J Infect Dis. 2004;190:624-631.
-
(2004)
J Infect Dis
, vol.190
, pp. 624-631
-
-
Huang, W.1
Na, L.2
Fidel, P.L.3
Schwarzenberger, P.4
-
13
-
-
0032939561
-
Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitors
-
Antonysamy MA, Fanslow WC, Fu F, et al. Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitors. J Immunol. 1999; 162:577-584.
-
(1999)
J Immunol
, vol.162
, pp. 577-584
-
-
Antonysamy, M.A.1
Fanslow, W.C.2
Fu, F.3
-
14
-
-
0036063633
-
Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejection
-
Loong CC, Hsieh HG, Lui WY, Chen A, Lin CY. Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejection. J Pathol. 2002;197:322-332.
-
(2002)
J Pathol
, vol.197
, pp. 322-332
-
-
Loong, C.C.1
Hsieh, H.G.2
Lui, W.Y.3
Chen, A.4
Lin, C.Y.5
-
15
-
-
33748286452
-
The role of interleukin-17 during acute rejection after lung transplantation
-
Vanaudenaerde BM, DuPont LJ, Wuyts WA, et al. The role of interleukin-17 during acute rejection after lung transplantation. Eur Respir J. 2006;27: 779-787.
-
(2006)
Eur Respir J
, vol.27
, pp. 779-787
-
-
Vanaudenaerde, B.M.1
DuPont, L.J.2
Wuyts, W.A.3
-
16
-
-
0037216498
-
Increased expression of interleukin 17 in inflammatory bowel disease
-
Fujino S, Andoh A, Bamba S, et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut. 2003;52:65-70.
-
(2003)
Gut
, vol.52
, pp. 65-70
-
-
Fujino, S.1
Andoh, A.2
Bamba, S.3
-
17
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
Nakae S, Nambu A, Sudo K, Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol. 2003; 171:6173-6177.
-
(2003)
J Immunol
, vol.171
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
18
-
-
33646433989
-
Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
-
Chen Y, Langrish CL, McKenzie B, et al. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J Clin Invest. 2006;116:1317-1326.
-
(2006)
J Clin Invest
, vol.116
, pp. 1317-1326
-
-
Chen, Y.1
Langrish, C.L.2
McKenzie, B.3
-
19
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen D, Cheung J, Scheerens H, et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest. 2006;116:1310-1316.
-
(2006)
J Clin Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
-
20
-
-
0029555301
-
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
-
Yao Z, Fanslow WC, Seldin MF, et al. Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity. 1995;3:811-821.
-
(1995)
Immunity
, vol.3
, pp. 811-821
-
-
Yao, Z.1
Fanslow, W.C.2
Seldin, M.F.3
-
21
-
-
38849097777
-
An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment
-
Liang SC, Long AJ, Bennett F, et al. An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment. J Immunol. 2007;179:7791-7799.
-
(2007)
J Immunol
, vol.179
, pp. 7791-7799
-
-
Liang, S.C.1
Long, A.J.2
Bennett, F.3
-
22
-
-
33846906224
-
Interleukin- 22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
Zheng Y, Danilenko DM, Valdez P, et al. Interleukin- 22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature. 2007;445:648-651.
-
(2007)
Nature
, vol.445
, pp. 648-651
-
-
Zheng, Y.1
Danilenko, D.M.2
Valdez, P.3
-
23
-
-
14844342604
-
IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
-
Boniface K, Bernard FX, Garcia M, Gurney AL, Lecron JC, Morel F. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J Immunol. 2005;174:3695-3702.
-
(2005)
J Immunol
, vol.174
, pp. 3695-3702
-
-
Boniface, K.1
Bernard, F.X.2
Garcia, M.3
Gurney, A.L.4
Lecron, J.C.5
Morel, F.6
-
24
-
-
33750712522
-
Keratinocytes as targets for interleukin-10-related cytokines: A putative role in the pathogenesis of psoriasis
-
Boniface K, Lecron JC, Bernard FX, et al. Keratinocytes as targets for interleukin-10-related cytokines: a putative role in the pathogenesis of psoriasis. Eur Cytokine Netw. 2005;16:309-319.
-
(2005)
Eur Cytokine Netw
, vol.16
, pp. 309-319
-
-
Boniface, K.1
Lecron, J.C.2
Bernard, F.X.3
-
25
-
-
33646552450
-
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis
-
Wolk K, Witte E, Wallace E, et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol. 2006;36:1309-1323.
-
(2006)
Eur J Immunol
, vol.36
, pp. 1309-1323
-
-
Wolk, K.1
Witte, E.2
Wallace, E.3
-
26
-
-
24144477540
-
Interleukin- 22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts
-
Andoh A, Zhang Z, Inatomi O, et al. Interleukin- 22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts. Gastroenterology. 2005;129:969-984.
-
(2005)
Gastroenterology
, vol.129
, pp. 969-984
-
-
Andoh, A.1
Zhang, Z.2
Inatomi, O.3
-
27
-
-
33645829078
-
IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
-
Brand S, Beigel F, Olszak T, et al. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am J Physiol Gastrointest Liver Physiol. 2006;290:G827-838.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Brand, S.1
Beigel, F.2
Olszak, T.3
-
28
-
-
34247573902
-
Graft-versus-host disease
-
Shlomchik WD. Graft-versus-host disease. Nat Rev Immunol. 2007;7:340-352.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 340-352
-
-
Shlomchik, W.D.1
-
29
-
-
0036550199
-
Cytolytic pathways in haematopoietic stem-cell transplantation
-
van den Brink MR, Burakoff SJ. Cytolytic pathways in haematopoietic stem-cell transplantation. Nat Rev Immunol. 2002;2:273-281.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 273-281
-
-
van den Brink, M.R.1
Burakoff, S.J.2
-
30
-
-
14944370670
-
Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: Requirements depend on target organ
-
Anderson BE, McNiff JM, Jain D, Blazar BR, Shlomchik WD, Shlomchik MJ. Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ. Blood. 2005;105:2227-2234.
-
(2005)
Blood
, vol.105
, pp. 2227-2234
-
-
Anderson, B.E.1
McNiff, J.M.2
Jain, D.3
Blazar, B.R.4
Shlomchik, W.D.5
Shlomchik, M.J.6
-
31
-
-
0027452843
-
Differential cytokine expression in acute and chronic murine graft-versus-host-disease
-
Allen RD, Staley TA, Sidman CL. Differential cytokine expression in acute and chronic murine graft-versus-host-disease. Eur J Immunol. 1993; 23:333-337.
-
(1993)
Eur J Immunol
, vol.23
, pp. 333-337
-
-
Allen, R.D.1
Staley, T.A.2
Sidman, C.L.3
-
32
-
-
0027410737
-
Cytokine storm of graft-versus-host disease: A critical effector role for interleukin-1
-
Ferrara JL, Abhyankar S, Gilliland DG. Cytokine storm of graft-versus-host disease: a critical effector role for interleukin-1. Transplant Proc. 1993;25:1216-1217.
-
(1993)
Transplant Proc
, vol.25
, pp. 1216-1217
-
-
Ferrara, J.L.1
Abhyankar, S.2
Gilliland, D.G.3
-
33
-
-
0027462749
-
Selective inhibition of CD4 graft-versus-host activity in IL-2-treated mice
-
Sykes M, Abraham VS, Harty MW, Pearson DA. Selective inhibition of CD4 graft-versus-host activity in IL-2-treated mice. Transplant Proc. 1993; 25:1225-1226.
-
(1993)
Transplant Proc
, vol.25
, pp. 1225-1226
-
-
Sykes, M.1
Abraham, V.S.2
Harty, M.W.3
Pearson, D.A.4
-
34
-
-
0030472390
-
Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graftversus- host disease
-
Krenger W, Cooke KR, Crawford JM, et al. Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graftversus- host disease. Transplantation. 1996;62: 1278-1285.
-
(1996)
Transplantation
, vol.62
, pp. 1278-1285
-
-
Krenger, W.1
Cooke, K.R.2
Crawford, J.M.3
-
35
-
-
0034103630
-
Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets
-
Nikolic B, Lee S, Bronson RT, Grusby MJ, Sykes M. Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets. J Clin Invest. 2000;105:1289-1298.
-
(2000)
J Clin Invest
, vol.105
, pp. 1289-1298
-
-
Nikolic, B.1
Lee, S.2
Bronson, R.T.3
Grusby, M.J.4
Sykes, M.5
-
36
-
-
10744230688
-
LPAM (alpha 4 beta 7 integrin) is an important homing integrin on alloreactive T cells in the development of intestinal graft-versus-host disease
-
Petrovic A, Alpdogan O, Willis LM, et al. LPAM (alpha 4 beta 7 integrin) is an important homing integrin on alloreactive T cells in the development of intestinal graft-versus-host disease. Blood. 2004;103:1542-1547.
-
(2004)
Blood
, vol.103
, pp. 1542-1547
-
-
Petrovic, A.1
Alpdogan, O.2
Willis, L.M.3
-
37
-
-
36348980530
-
Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease
-
Chen X, Vodanovic-Jankovic S, Johnson B, Keller M, Komorowski R, Drobyski WR. Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease. Blood. 2007;110:3804-3813.
-
(2007)
Blood
, vol.110
, pp. 3804-3813
-
-
Chen, X.1
Vodanovic-Jankovic, S.2
Johnson, B.3
Keller, M.4
Komorowski, R.5
Drobyski, W.R.6
-
38
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn T, Bettelli E, Gao W, et al. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature. 2007;448:484-487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
-
39
-
-
43549110961
-
Regulation of inflammatory responses by IL-17F
-
Yang XO, Chang SH, Park H, et al. Regulation of inflammatory responses by IL-17F. J Exp Med. 2008;205:1063-1075.
-
(2008)
J Exp Med
, vol.205
, pp. 1063-1075
-
-
Yang, X.O.1
Chang, S.H.2
Park, H.3
-
40
-
-
47649122633
-
Tumor-specific Th17-polarized cells eradicate large established melanoma
-
Muranski P, Boni A, Antony PA, et al. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood. 2008;112:362-373.
-
(2008)
Blood
, vol.112
, pp. 362-373
-
-
Muranski, P.1
Boni, A.2
Antony, P.A.3
-
41
-
-
34248562792
-
IL-23 and IL-17 in the establishment of protective pulmonary CD4-T cell responses after vaccination and during Mycobacterium tuberculosis challenge
-
Khader SA, Bell GK, Pearl JE, et al. IL-23 and IL-17 in the establishment of protective pulmonary CD4-T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol. 2007;8:369-377.
-
(2007)
Nat Immunol
, vol.8
, pp. 369-377
-
-
Khader, S.A.1
Bell, G.K.2
Pearl, J.E.3
-
42
-
-
0031691282
-
Interleukin-17 and interferon- gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes
-
Teunissen MB, Koomen CW, de Waal Malefyt R, Wierenga EA, Bos JD. Interleukin-17 and interferon- gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes. J Invest Dermatol. 1998;111:645-649.
-
(1998)
J Invest Dermatol
, vol.111
, pp. 645-649
-
-
Teunissen, M.B.1
Koomen, C.W.2
de Waal Malefyt, R.3
Wierenga, E.A.4
Bos, J.D.5
-
43
-
-
52649136967
-
Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease
-
Yi T, Zhao D, Lin CL, et al. Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease. Blood. 2008;112:2101-2110.
-
(2008)
Blood
, vol.112
, pp. 2101-2110
-
-
Yi, T.1
Zhao, D.2
Lin, C.L.3
-
44
-
-
0031826580
-
The cytokine modulation of acute graft-versus-host disease
-
Ferrara JL. The cytokine modulation of acute graft-versus-host disease. Bone Marrow Transplant. 1998;21 Suppl 3:S13-15.
-
(1998)
Bone Marrow Transplant
, vol.21
, Issue.SUPPL. 3
-
-
Ferrara, J.L.1
-
45
-
-
34547103280
-
Absence of donor T-cell-derived soluble TNF decreases graft-versus-host disease without impairing graftversus- tumor activity
-
Borsotti C, Franklin AR, Lu SX, et al. Absence of donor T-cell-derived soluble TNF decreases graft-versus-host disease without impairing graftversus- tumor activity. Blood. 2007;110:783-786.
-
(2007)
Blood
, vol.110
, pp. 783-786
-
-
Borsotti, C.1
Franklin, A.R.2
Lu, S.X.3
-
46
-
-
15244344110
-
Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
-
Stark MA, Huo Y, Burcin TL, Morris MA, Olson TS, Ley K. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity. 2005;22:285-294.
-
(2005)
Immunity
, vol.22
, pp. 285-294
-
-
Stark, M.A.1
Huo, Y.2
Burcin, T.L.3
Morris, M.A.4
Olson, T.S.5
Ley, K.6
-
47
-
-
38749143286
-
Interleukin- 17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
-
Tzartos JS, Friese MA, Craner MJ, et al. Interleukin- 17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol. 2008;172:146-155.
-
(2008)
Am J Pathol
, vol.172
, pp. 146-155
-
-
Tzartos, J.S.1
Friese, M.A.2
Craner, M.J.3
-
48
-
-
33747089041
-
Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
-
Uhlig HH, McKenzie BS, Hue S, et al. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity. 2006; 25:309-318.
-
(2006)
Immunity
, vol.25
, pp. 309-318
-
-
Uhlig, H.H.1
McKenzie, B.S.2
Hue, S.3
-
49
-
-
53749102607
-
IL-17A is produced by Th17, gammadelta T cells and other CD4-lymphocytes during infection with Salmonella enterica serovar Enteritidis and has a mild effect in bacterial clearance
-
Schulz SM, Kohler G, Holscher C, Iwakura Y, Alber G. IL-17A is produced by Th17, gammadelta T cells and other CD4-lymphocytes during infection with Salmonella enterica serovar Enteritidis and has a mild effect in bacterial clearance. Int Immunol. 2008;20:1129-1138.
-
(2008)
Int Immunol
, vol.20
, pp. 1129-1138
-
-
Schulz, S.M.1
Kohler, G.2
Holscher, C.3
Iwakura, Y.4
Alber, G.5
|