-
2
-
-
34250212629
-
The transcriptional regulation of B cell lineage commitment
-
2 Nutt, S.L., Kee, B.L., The transcriptional regulation of B cell lineage commitment. Immunity 26 (2007), 715–725.
-
(2007)
Immunity
, vol.26
, pp. 715-725
-
-
Nutt, S.L.1
Kee, B.L.2
-
3
-
-
33847690322
-
Terminal differentiation of lymphocytes depends on Blimp-1
-
3 Kallies, A., Nutt, S.L., Terminal differentiation of lymphocytes depends on Blimp-1. Curr. Opin. Immunol. 19 (2007), 156–162.
-
(2007)
Curr. Opin. Immunol.
, vol.19
, pp. 156-162
-
-
Kallies, A.1
Nutt, S.L.2
-
4
-
-
84886790466
-
T-bet: a bridge between innate and adaptive immunity
-
4 Lazarevic, V., et al. T-bet: a bridge between innate and adaptive immunity. Nat. Rev. Immunol. 13 (2013), 777–789.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 777-789
-
-
Lazarevic, V.1
-
5
-
-
84969754451
-
+ T cells against microbes
-
+ T cells against microbes. Annu. Rev. Immunol. 34 (2016), 317–334.
-
(2016)
Annu. Rev. Immunol.
, vol.34
, pp. 317-334
-
-
Sallusto, F.1
-
6
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
6 Szabo, S.J., et al. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100 (2000), 655–669.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
-
7
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
7 Zheng, W., Flavell, R.A., The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89 (1997), 587–596.
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
8
-
-
69249109601
-
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
-
8 Johnston, R.J., et al. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science 325 (2009), 1006–1010.
-
(2009)
Science
, vol.325
, pp. 1006-1010
-
-
Johnston, R.J.1
-
9
-
-
70049101558
-
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment
-
9 Yu, D., et al. The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity 31 (2009), 457–468.
-
(2009)
Immunity
, vol.31
, pp. 457-468
-
-
Yu, D.1
-
10
-
-
69249101229
-
Bcl6 mediates the development of T follicular helper cells
-
10 Nurieva, R.I., et al. Bcl6 mediates the development of T follicular helper cells. Science 325 (2009), 1001–1005.
-
(2009)
Science
, vol.325
, pp. 1001-1005
-
-
Nurieva, R.I.1
-
11
-
-
84255178198
-
Early Th1 cell differentiation is marked by a Tfh cell-like transition
-
11 Nakayamada, S., et al. Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity 35 (2011), 919–931.
-
(2011)
Immunity
, vol.35
, pp. 919-931
-
-
Nakayamada, S.1
-
12
-
-
80755172184
-
Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells
-
12 Pepper, M., et al. Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity 35 (2011), 583–595.
-
(2011)
Immunity
, vol.35
, pp. 583-595
-
-
Pepper, M.1
-
13
-
-
80755163540
-
+ cell properties during viral infection
-
+ cell properties during viral infection. Immunity 35 (2011), 633–646.
-
(2011)
Immunity
, vol.35
, pp. 633-646
-
-
Marshall, H.D.1
-
14
-
-
79956201473
-
The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns
-
14 Oestreich, K.J., et al. The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns. J. Exp. Med. 208 (2011), 1001–1013.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1001-1013
-
-
Oestreich, K.J.1
-
15
-
-
84952978140
-
Severe malaria infections impair germinal center responses by inhibiting T follicular helper cell differentiation
-
15 Ryg-Cornejo, V., et al. Severe malaria infections impair germinal center responses by inhibiting T follicular helper cell differentiation. Cell Rep. 14 (2016), 68–81.
-
(2016)
Cell Rep.
, vol.14
, pp. 68-81
-
-
Ryg-Cornejo, V.1
-
16
-
-
78751690647
-
+ T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion
-
+ T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity 34 (2011), 108–121.
-
(2011)
Immunity
, vol.34
, pp. 108-121
-
-
Morita, R.1
-
17
-
-
84885743368
-
+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses
-
+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses. Immunity 39 (2013), 758–769.
-
(2013)
Immunity
, vol.39
, pp. 758-769
-
-
Locci, M.1
-
18
-
-
84958259928
-
Reversible reprogramming of circulating memory T follicular helper cell function during chronic HIV infection
-
18 Cubas, R., et al. Reversible reprogramming of circulating memory T follicular helper cell function during chronic HIV infection. J. Immunol. 195 (2015), 5625–5636.
-
(2015)
J. Immunol.
, vol.195
, pp. 5625-5636
-
-
Cubas, R.1
-
19
-
-
84878454838
-
Inadequate T follicular cell help impairs B cell immunity during HIV infection
-
19 Cubas, R.A., et al. Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat. Med. 19 (2013), 494–499.
-
(2013)
Nat. Med.
, vol.19
, pp. 494-499
-
-
Cubas, R.A.1
-
20
-
-
84983776546
-
Induction of Th1-biased T follicular helper (Tfh) cells in lymphoid tissues during chronic simian immunodeficiency virus infection defines functionally distinct germinal center Tfh cells
-
20 Velu, V., et al. Induction of Th1-biased T follicular helper (Tfh) cells in lymphoid tissues during chronic simian immunodeficiency virus infection defines functionally distinct germinal center Tfh cells. J. Immunol. 197 (2016), 1832–1842.
-
(2016)
J. Immunol.
, vol.197
, pp. 1832-1842
-
-
Velu, V.1
-
21
-
-
84992702535
-
Protective neutralizing influenza antibody response in the absence of T follicular helper cells
-
21 Miyauchi, K., et al. Protective neutralizing influenza antibody response in the absence of T follicular helper cells. Nat. Immunol. 17 (2016), 1447–1458.
-
(2016)
Nat. Immunol.
, vol.17
, pp. 1447-1458
-
-
Miyauchi, K.1
-
22
-
-
74049131014
-
Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells
-
22 Pepper, M., et al. Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells. Nat. Immunol. 11 (2010), 83–89.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 83-89
-
-
Pepper, M.1
-
23
-
-
84866532132
-
Induction and molecular signature of pathogenic TH17 cells
-
23 Lee, Y., et al. Induction and molecular signature of pathogenic TH17 cells. Nat. Immunol. 13 (2012), 991–999.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 991-999
-
-
Lee, Y.1
-
24
-
-
84949196321
-
CD5L/AIM regulates lipid biosynthesis and restrains Th17 cell pathogenicity
-
24 Wang, C., et al. CD5L/AIM regulates lipid biosynthesis and restrains Th17 cell pathogenicity. Cell 163 (2015), 1413–1427.
-
(2015)
Cell
, vol.163
, pp. 1413-1427
-
-
Wang, C.1
-
25
-
-
79951677394
-
Fate mapping of IL-17-producing T cells in inflammatory responses
-
25 Hirota, K., et al. Fate mapping of IL-17-producing T cells in inflammatory responses. Nat. Immunol. 12 (2011), 255–263.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 255-263
-
-
Hirota, K.1
-
26
-
-
67650433931
-
T-bet is essential for encephalitogenicity of both Th1 and Th17 cells
-
26 Yang, Y., et al. T-bet is essential for encephalitogenicity of both Th1 and Th17 cells. J. Exp. Med. 206 (2009), 1549–1564.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1549-1564
-
-
Yang, Y.1
-
27
-
-
84896402211
-
The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-gamma-producing T helper 17 cells
-
27 Wang, Y., et al. The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-gamma-producing T helper 17 cells. Immunity 40 (2014), 355–366.
-
(2014)
Immunity
, vol.40
, pp. 355-366
-
-
Wang, Y.1
-
28
-
-
84969921427
-
+ T cell responses in the intestine
-
+ T cell responses in the intestine. Nat. Commun., 7, 2016, 11627.
-
(2016)
Nat. Commun.
, vol.7
, pp. 11627
-
-
Krausgruber, T.1
-
29
-
-
34548027000
-
+ T cell fates via the graded expression of T-bet transcription factor
-
+ T cell fates via the graded expression of T-bet transcription factor. Immunity 27 (2007), 281–295.
-
(2007)
Immunity
, vol.27
, pp. 281-295
-
-
Joshi, N.S.1
-
30
-
-
47749141467
-
+ T cells lacking T-bet and eomesodermin
-
+ T cells lacking T-bet and eomesodermin. Science 321 (2008), 408–411.
-
(2008)
Science
, vol.321
, pp. 408-411
-
-
Intlekofer, A.M.1
-
31
-
-
30044440799
-
+ T cell fate coupled by T-bet and eomesodermin
-
+ T cell fate coupled by T-bet and eomesodermin. Nat. Immunol. 6 (2005), 1236–1244.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1236-1244
-
-
Intlekofer, A.M.1
-
32
-
-
0242410712
-
+ T cell function by the transcription factor Eomesodermin
-
+ T cell function by the transcription factor Eomesodermin. Science 302 (2003), 1041–1043.
-
(2003)
Science
, vol.302
, pp. 1041-1043
-
-
Pearce, E.L.1
-
33
-
-
79959375167
-
+ T cell responses during chronic infection
-
+ T cell responses during chronic infection. Nat. Immunol. 12 (2011), 663–671.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 663-671
-
-
Kao, C.1
-
34
-
-
84870230232
-
+ T cells cooperate to contain chronic viral infection
-
+ T cells cooperate to contain chronic viral infection. Science 338 (2012), 1220–1225.
-
(2012)
Science
, vol.338
, pp. 1220-1225
-
-
Paley, M.A.1
-
35
-
-
84971523245
-
The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection
-
35 Dominguez, C.X., et al. The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection. J. Exp. Med. 212 (2015), 2041–2056.
-
(2015)
J. Exp. Med.
, vol.212
, pp. 2041-2056
-
-
Dominguez, C.X.1
-
36
-
-
84960194165
-
+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet
-
+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet. Nat. Immunol. 17 (2016), 422–432.
-
(2016)
Nat. Immunol.
, vol.17
, pp. 422-432
-
-
Xin, A.1
-
37
-
-
84908127758
-
+ T cells during influenza viral infection
-
+ T cells during influenza viral infection. Immunity 41 (2014), 633–645.
-
(2014)
Immunity
, vol.41
, pp. 633-645
-
-
Laidlaw, B.J.1
-
38
-
-
84963543332
-
T-box transcription factors combine with the cytokines TGF-beta and IL-15 to control tissue-resident memory T cell fate
-
38 Mackay, L.K., et al. T-box transcription factors combine with the cytokines TGF-beta and IL-15 to control tissue-resident memory T cell fate. Immunity 43 (2015), 1101–1111.
-
(2015)
Immunity
, vol.43
, pp. 1101-1111
-
-
Mackay, L.K.1
-
39
-
-
84964887792
-
Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes
-
39 Mackay, L.K., et al. Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes. Science 352 (2016), 459–463.
-
(2016)
Science
, vol.352
, pp. 459-463
-
-
Mackay, L.K.1
-
40
-
-
84976272630
-
NK cells and type 1 innate lymphoid cells: partners in host defense
-
40 Spits, H., et al. NK cells and type 1 innate lymphoid cells: partners in host defense. Nat. Immunol. 17 (2016), 758–764.
-
(2016)
Nat. Immunol.
, vol.17
, pp. 758-764
-
-
Spits, H.1
-
41
-
-
84896847858
-
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
-
41 Daussy, C., et al. T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow. J. Exp. Med. 211 (2014), 563–577.
-
(2014)
J. Exp. Med.
, vol.211
, pp. 563-577
-
-
Daussy, C.1
-
42
-
-
84898640432
-
Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages
-
42 Klose, C.S., et al. Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages. Cell 157 (2014), 340–356.
-
(2014)
Cell
, vol.157
, pp. 340-356
-
-
Klose, C.S.1
-
43
-
-
84862777436
-
The transcription factors T-bet and eomes control key checkpoints of natural killer cell maturation
-
43 Gordon, S.M., et al. The transcription factors T-bet and eomes control key checkpoints of natural killer cell maturation. Immunity 36 (2012), 55–67.
-
(2012)
Immunity
, vol.36
, pp. 55-67
-
-
Gordon, S.M.1
-
44
-
-
84977471548
-
T-bet and eomesodermin in NK cell development, maturation, and function
-
44 Simonetta, F., et al. T-bet and eomesodermin in NK cell development, maturation, and function. Front. Immunol., 7, 2016, 241.
-
(2016)
Front. Immunol.
, vol.7
, pp. 241
-
-
Simonetta, F.1
-
45
-
-
84875445419
-
The transcription factor T-bet is essential for the development of NKp46 innate lymphocytes via the Notch pathway
-
45 Rankin, L.C., et al. The transcription factor T-bet is essential for the development of NKp46 innate lymphocytes via the Notch pathway. Nat. Immunol. 14 (2013), 389–395.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 389-395
-
-
Rankin, L.C.1
-
46
-
-
84997701962
-
Adipose-resident group 1 innate lymphoid cells promote obesity-associated insulin resistance
-
46 O'sullivan, T.E., et al. Adipose-resident group 1 innate lymphoid cells promote obesity-associated insulin resistance. Immunity 45 (2016), 428–441.
-
(2016)
Immunity
, vol.45
, pp. 428-441
-
-
O'sullivan, T.E.1
-
47
-
-
79951470129
-
A role for Blimp1 in the transcriptional network controlling natural killer cell maturation
-
47 Kallies, A., et al. A role for Blimp1 in the transcriptional network controlling natural killer cell maturation. Blood 117 (2011), 1869–1879.
-
(2011)
Blood
, vol.117
, pp. 1869-1879
-
-
Kallies, A.1
-
48
-
-
1842785209
-
T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells
-
48 Townsend, M.J., et al. T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity 20 (2004), 477–494.
-
(2004)
Immunity
, vol.20
, pp. 477-494
-
-
Townsend, M.J.1
-
49
-
-
84907365390
-
+ intraepithelial lymphocyte development
-
+ intraepithelial lymphocyte development. Immunity 41 (2014), 230–243.
-
(2014)
Immunity
, vol.41
, pp. 230-243
-
-
Klose, C.S.1
-
50
-
-
84886673181
-
Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells
-
50 Lee, Y.J., et al. Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells. Nat. Immunol. 14 (2013), 1146–1154.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 1146-1154
-
-
Lee, Y.J.1
-
51
-
-
84867856710
-
+ innate lymphoid cells
-
+ innate lymphoid cells. Immunity 37 (2012), 674–684.
-
(2012)
Immunity
, vol.37
, pp. 674-684
-
-
Powell, N.1
-
52
-
-
84883801440
-
Diversity among memory B cells: origin, consequences, and utility
-
52 Tarlinton, D., Good-Jacobson, K., Diversity among memory B cells: origin, consequences, and utility. Science 341 (2013), 1205–1211.
-
(2013)
Science
, vol.341
, pp. 1205-1211
-
-
Tarlinton, D.1
Good-Jacobson, K.2
-
53
-
-
0037117557
-
T-bet regulates IgG class switching and pathogenic autoantibody production
-
53 Peng, S.L., et al. T-bet regulates IgG class switching and pathogenic autoantibody production. Proc. Natl. Acad. Sci. U. S. A. 99 (2002), 5545–5550.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 5545-5550
-
-
Peng, S.L.1
-
54
-
-
84861235461
-
Divergent transcriptional programming of class-specific B cell memory by T-bet and RORalpha
-
54 Wang, N.S., et al. Divergent transcriptional programming of class-specific B cell memory by T-bet and RORalpha. Nat. Immunol. 13 (2012), 604–611.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 604-611
-
-
Wang, N.S.1
-
55
-
-
0041522519
-
T-bet regulates T-independent IgG2a class switching
-
55 Gerth, A.J., et al. T-bet regulates T-independent IgG2a class switching. Int. Immunol. 15 (2003), 937–944.
-
(2003)
Int. Immunol.
, vol.15
, pp. 937-944
-
-
Gerth, A.J.1
-
56
-
-
84969245659
-
B cell IFN-gamma receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6
-
56 Jackson, S.W., et al. B cell IFN-gamma receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. J. Exp. Med. 213 (2016), 733–750.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 733-750
-
-
Jackson, S.W.1
-
57
-
-
0038639600
-
CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells
-
57 Liu, N., et al. CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells. Nat. Immunol. 4 (2003), 687–693.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 687-693
-
-
Liu, N.1
-
58
-
-
76249112770
-
IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
-
58 Kashiwada, M., et al. IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 821–826.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 821-826
-
-
Kashiwada, M.1
-
59
-
-
66049120992
-
Ikaros controls isotype selection during immunoglobulin class switch recombination
-
59 Sellars, M., et al. Ikaros controls isotype selection during immunoglobulin class switch recombination. J. Exp. Med. 206 (2009), 1073–1087.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1073-1087
-
-
Sellars, M.1
-
60
-
-
84983784437
-
Cutting edge: B cell-intrinsic T-bet expression is required to control chronic viral infection
-
60 Barnett, B.E., et al. Cutting edge: B cell-intrinsic T-bet expression is required to control chronic viral infection. J. Immunol. 197 (2016), 1017–1022.
-
(2016)
J. Immunol.
, vol.197
, pp. 1017-1022
-
-
Barnett, B.E.1
-
61
-
-
31544463262
-
Long-lived plasma cells in immunity and immunopathology
-
61 Moser, K., et al. Long-lived plasma cells in immunity and immunopathology. Immunol. Lett. 103 (2006), 83–85.
-
(2006)
Immunol. Lett.
, vol.103
, pp. 83-85
-
-
Moser, K.1
-
62
-
-
84882759383
-
T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance
-
62 Rubtsova, K., et al. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proc. Natl. Acad. Sci. U. S. A. 110 (2013), E3216–E3224.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. E3216-E3224
-
-
Rubtsova, K.1
-
63
-
-
80051569441
-
A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
-
63 Hao, Y., et al. A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. Blood 118 (2011), 1294–1304.
-
(2011)
Blood
, vol.118
, pp. 1294-1304
-
-
Hao, Y.1
-
64
-
-
80051568169
-
+ B-cell population is important for the development of autoimmunity
-
+ B-cell population is important for the development of autoimmunity. Blood 118 (2011), 1305–1315.
-
(2011)
Blood
, vol.118
, pp. 1305-1315
-
-
Rubtsov, A.V.1
-
65
-
-
84969132610
-
IFN-gamma receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity
-
65 Domeier, P.P., et al. IFN-gamma receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity. J. Exp. Med. 213 (2016), 715–732.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 715-732
-
-
Domeier, P.P.1
-
66
-
-
18944370055
-
Regulation of IFN-gamma production by B effector 1 cells: essential roles for T-bet and the IFN-gamma receptor
-
66 Harris, D.P., et al. Regulation of IFN-gamma production by B effector 1 cells: essential roles for T-bet and the IFN-gamma receptor. J. Immunol. 174 (2005), 6781–6790.
-
(2005)
J. Immunol.
, vol.174
, pp. 6781-6790
-
-
Harris, D.P.1
-
67
-
-
28244458933
-
Cutting edge: the development of IL-4-producing B cells (B effector 2 cells) is controlled by IL-4, IL-4 receptor alpha, and Th2 cells
-
67 Harris, D.P., et al. Cutting edge: the development of IL-4-producing B cells (B effector 2 cells) is controlled by IL-4, IL-4 receptor alpha, and Th2 cells. J. Immunol. 175 (2005), 7103–7107.
-
(2005)
J. Immunol.
, vol.175
, pp. 7103-7107
-
-
Harris, D.P.1
-
68
-
-
0034568991
-
Reciprocal regulation of polarized cytokine production by effector B and T cells
-
68 Harris, D.P., et al. Reciprocal regulation of polarized cytokine production by effector B and T cells. Nat. Immunol. 1 (2000), 475–482.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 475-482
-
-
Harris, D.P.1
-
69
-
-
84983760966
-
Cutting edge: IL-4, IL-21, and IFN-γ interact to govern T-bet and CD11c expression in TLR-activated B cells
-
69 Naradikian, M.S., et al. Cutting edge: IL-4, IL-21, and IFN-γ interact to govern T-bet and CD11c expression in TLR-activated B cells. J. Immunol. 197 (2016), 1023–1028.
-
(2016)
J. Immunol.
, vol.197
, pp. 1023-1028
-
-
Naradikian, M.S.1
-
70
-
-
79952091851
-
CXCR3 in T cell function
-
70 Groom, J.R., Luster, A.D., CXCR3 in T cell function. Exp. Cell Res. 317 (2011), 620–631.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 620-631
-
-
Groom, J.R.1
Luster, A.D.2
-
71
-
-
33947190910
-
Temporal dissection of T-bet functions
-
71 Matsuda, J.L., et al. Temporal dissection of T-bet functions. J. Immunol. 178 (2007), 3457–3465.
-
(2007)
J. Immunol.
, vol.178
, pp. 3457-3465
-
-
Matsuda, J.L.1
-
72
-
-
0032536869
-
Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
-
72 Sallusto, F., et al. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J. Exp. Med. 187 (1998), 875–883.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 875-883
-
-
Sallusto, F.1
-
73
-
-
84870491540
-
CD8 T cells induce T-bet-dependent migration toward CXCR3 ligands by differentiated B cells produced during responses to alum-protein vaccines
-
73 Serre, K., et al. CD8 T cells induce T-bet-dependent migration toward CXCR3 ligands by differentiated B cells produced during responses to alum-protein vaccines. Blood 120 (2012), 4552–4559.
-
(2012)
Blood
, vol.120
, pp. 4552-4559
-
-
Serre, K.1
-
74
-
-
84857125483
-
Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection
-
74 Onodera, T., et al. Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 2485–2490.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 2485-2490
-
-
Onodera, T.1
-
75
-
-
84870864876
-
+ T helper 1 cell differentiation
-
+ T helper 1 cell differentiation. Immunity 37 (2012), 1091–1103.
-
(2012)
Immunity
, vol.37
, pp. 1091-1103
-
-
Groom, J.R.1
-
76
-
-
78649853665
-
T-bet and eomesodermin are required for T cell-mediated antitumor immune responses
-
76 Zhu, Y., et al. T-bet and eomesodermin are required for T cell-mediated antitumor immune responses. J. Immunol. 185 (2010), 3174–3183.
-
(2010)
J. Immunol.
, vol.185
, pp. 3174-3183
-
-
Zhu, Y.1
-
77
-
-
78649263390
-
Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression
-
77 Miller, S.A., et al. Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression. Mol. Cell 40 (2010), 594–605.
-
(2010)
Mol. Cell
, vol.40
, pp. 594-605
-
-
Miller, S.A.1
-
78
-
-
80054722812
-
Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells
-
78 Joshi, N.S., et al. Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells. J. Immunol. 187 (2011), 4068–4076.
-
(2011)
J. Immunol.
, vol.187
, pp. 4068-4076
-
-
Joshi, N.S.1
-
79
-
-
84887515800
-
+ T cells are critical for protection against influenza A virus
-
+ T cells are critical for protection against influenza A virus. Immunity 39 (2013), 939–948.
-
(2013)
Immunity
, vol.39
, pp. 939-948
-
-
Slutter, B.1
-
80
-
-
68249134207
-
KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors
-
80 Weinreich, M.A., et al. KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors. Immunity 31 (2009), 122–130.
-
(2009)
Immunity
, vol.31
, pp. 122-130
-
-
Weinreich, M.A.1
-
81
-
-
84870027825
-
STATs shape the active enhancer landscape of T cell populations
-
81 Vahedi, G., et al. STATs shape the active enhancer landscape of T cell populations. Cell 151 (2012), 981–993.
-
(2012)
Cell
, vol.151
, pp. 981-993
-
-
Vahedi, G.1
-
82
-
-
79957708430
-
Expression of chemokine receptor CXCR3 on T cells affects the balance between effector and memory CD8 T-cell generation
-
82 Hu, J.K., et al. Expression of chemokine receptor CXCR3 on T cells affects the balance between effector and memory CD8 T-cell generation. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), E118–E127.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. E118-E127
-
-
Hu, J.K.1
-
83
-
-
65749103365
-
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
-
83 Koch, M.A., et al. The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat. Immunol. 10 (2009), 595–602.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 595-602
-
-
Koch, M.A.1
-
84
-
-
84923035090
-
Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance
-
84 Yu, F., et al. Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance. Nat. Immunol. 16 (2015), 197–206.
-
(2015)
Nat. Immunol.
, vol.16
, pp. 197-206
-
-
Yu, F.1
-
85
-
-
84866483591
-
reg cell populations required to limit infection-induced pathology
-
reg cell populations required to limit infection-induced pathology. Immunity 37 (2012), 511–523.
-
(2012)
Immunity
, vol.37
, pp. 511-523
-
-
Hall, A.O.1
-
86
-
-
85016352384
-
T-bet enhances regulatory T cell fitness and directs control of Th1 responses in crescentic GN
-
86 Nosko, A., et al. T-bet enhances regulatory T cell fitness and directs control of Th1 responses in crescentic GN. J. Am. Soc. Nephrol. 28 (2017), 185–196.
-
(2017)
J. Am. Soc. Nephrol.
, vol.28
, pp. 185-196
-
-
Nosko, A.1
-
87
-
-
85003426944
-
Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice
-
87 Tan, T.G., et al. Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice. Proc. Natl. Acad. Sci. U. S. A. 113 (2016), E8141–E8150.
-
(2016)
Proc. Natl. Acad. Sci. U. S. A.
, vol.113
, pp. E8141-E8150
-
-
Tan, T.G.1
-
89
-
-
33751584436
-
+ T cell differentiation
-
+ T cell differentiation. J. Immunol. 177 (2006), 7515–7519.
-
(2006)
J. Immunol.
, vol.177
, pp. 7515-7519
-
-
Takemoto, N.1
-
90
-
-
0035827347
-
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
-
90 Mullen, A.C., et al. Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science 292 (2001), 1907–1910.
-
(2001)
Science
, vol.292
, pp. 1907-1910
-
-
Mullen, A.C.1
-
91
-
-
74549216531
-
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells
-
91 Pipkin, M.E., et al. Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity 32 (2010), 79–90.
-
(2010)
Immunity
, vol.32
, pp. 79-90
-
-
Pipkin, M.E.1
-
92
-
-
84856062668
-
+ T cells in vivo
-
+ T cells in vivo. Eur. J. Immunol. 42 (2012), 320–329.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 320-329
-
-
Wiesel, M.1
-
93
-
-
84944681622
-
The interleukin-2-mTORc1 kinase axis defines the signaling, differentiation, and metabolism of T helper 1 and follicular B helper T cells
-
93 Ray, J.P., et al. The interleukin-2-mTORc1 kinase axis defines the signaling, differentiation, and metabolism of T helper 1 and follicular B helper T cells. Immunity 43 (2015), 690–702.
-
(2015)
Immunity
, vol.43
, pp. 690-702
-
-
Ray, J.P.1
-
94
-
-
84866499256
-
reg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor beta2
-
reg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor beta2. Immunity 37 (2012), 501–510.
-
(2012)
Immunity
, vol.37
, pp. 501-510
-
-
Koch, M.A.1
-
95
-
-
33646467806
-
Differential effects of IL-27 on human B cell subsets
-
95 Larousserie, F., et al. Differential effects of IL-27 on human B cell subsets. J. Immunol. 176 (2006), 5890–5897.
-
(2006)
J. Immunol.
, vol.176
, pp. 5890-5897
-
-
Larousserie, F.1
-
96
-
-
4043122529
-
Induction of IgG2a class switching in B cells by IL-27
-
96 Yoshimoto, T., et al. Induction of IgG2a class switching in B cells by IL-27. J. Immunol. 173 (2004), 2479–2485.
-
(2004)
J. Immunol.
, vol.173
, pp. 2479-2485
-
-
Yoshimoto, T.1
-
97
-
-
28244472817
-
Stat1-dependent synergistic activation of T-bet for IgG2a production during early stage of B cell activation
-
97 Xu, W., Zhang, J.J., Stat1-dependent synergistic activation of T-bet for IgG2a production during early stage of B cell activation. J. Immunol. 175 (2005), 7419–7424.
-
(2005)
J. Immunol.
, vol.175
, pp. 7419-7424
-
-
Xu, W.1
Zhang, J.J.2
-
98
-
-
84860710456
-
The Ets-1 transcription factor is required for Stat1-mediated T-bet expression and IgG2a class switching in mouse B cells
-
98 Nguyen, H.V., et al. The Ets-1 transcription factor is required for Stat1-mediated T-bet expression and IgG2a class switching in mouse B cells. Blood 119 (2012), 4174–4181.
-
(2012)
Blood
, vol.119
, pp. 4174-4181
-
-
Nguyen, H.V.1
-
99
-
-
79956085895
-
Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages
-
99 Liao, W., et al. Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat. Immunol. 12 (2011), 551–559.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 551-559
-
-
Liao, W.1
-
100
-
-
84885156779
-
Active STAT5 regulates T-bet and eomesodermin expression in CD8 T cells and imprints a T-bet-dependent Tc1 program with repressed IL-6/TGF-beta1 signaling
-
100 Grange, M., et al. Active STAT5 regulates T-bet and eomesodermin expression in CD8 T cells and imprints a T-bet-dependent Tc1 program with repressed IL-6/TGF-beta1 signaling. J. Immunol. 191 (2013), 3712–3724.
-
(2013)
J. Immunol.
, vol.191
, pp. 3712-3724
-
-
Grange, M.1
-
101
-
-
84896372779
-
Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells
-
101 Ray, J.P., et al. Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells. Immunity 40 (2014), 367–377.
-
(2014)
Immunity
, vol.40
, pp. 367-377
-
-
Ray, J.P.1
-
102
-
-
0037013930
-
Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
-
102 Gorelik, L., et al. Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation. J. Exp. Med. 195 (2002), 1499–1505.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1499-1505
-
-
Gorelik, L.1
-
103
-
-
85002609650
-
+ T cells sustain the immune response to chronic viral infections
-
+ T cells sustain the immune response to chronic viral infections. Immunity 45 (2016), 415–427.
-
(2016)
Immunity
, vol.45
, pp. 415-427
-
-
Utzschneider, D.T.1
-
104
-
-
84988410229
-
+ T cells curtail chronic viral infection
-
+ T cells curtail chronic viral infection. Nature 537 (2016), 412–428.
-
(2016)
Nature
, vol.537
, pp. 412-428
-
-
He, R.1
-
105
-
-
84988266244
-
+ T cells that provide the proliferative burst after PD-1 therapy
-
+ T cells that provide the proliferative burst after PD-1 therapy. Nature 537 (2016), 417–421.
-
(2016)
Nature
, vol.537
, pp. 417-421
-
-
Im, S.J.1
-
106
-
-
84981285538
-
+ follicular cytotoxic T cells control viral infection in B cell follicles
-
+ follicular cytotoxic T cells control viral infection in B cell follicles. Nat. Immunol. 17 (2016), 1187–1196.
-
(2016)
Nat. Immunol.
, vol.17
, pp. 1187-1196
-
-
Leong, Y.A.1
-
107
-
-
84940450115
-
Synchronizing transcriptional control of T cell metabolism and function
-
107 Man, K., Kallies, A., Synchronizing transcriptional control of T cell metabolism and function. Nat. Rev. Immunol. 15 (2015), 574–584.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 574-584
-
-
Man, K.1
Kallies, A.2
-
108
-
-
84911132031
-
Bcl-6 directly represses the gene program of the glycolysis pathway
-
108 Oestreich, K.J., et al. Bcl-6 directly represses the gene program of the glycolysis pathway. Nat. Immunol. 15 (2014), 957–964.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 957-964
-
-
Oestreich, K.J.1
|