B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6

Journal of Experimental Medicine

Volumn 213, Issue 5, 2016, Pages 733-750

  Jackson, Shaun W ^a,b   Jacobs, Holly M ^a   Arkatkar, Tanvi ^a   Dam, Elizabeth M ^c   Scharping, Nicole E ^a   Kolhatkar, Nikita S ^a,b   Hou, Baidong ^d   Buckner, Jane H ^c   Rawlings, David J ^a,b  

^a SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c BENAROYA RESEARCH INSTITUTE   (United States)

^d INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; B LYMPHOCYTE ANTIGEN; B LYMPHOCYTE RECEPTOR; BETA INTERFERON; CD40 ANTIGEN; COMPLEMENT COMPONENT C3; GAMMA INTERFERON RECEPTOR; IMMUNOGLOBULIN M ANTIBODY; INTERFERON RECEPTOR; PEANUT AGGLUTININ; PROTEIN BCL 6; RESIQUIMOD; RUXOLITINIB; TOLL LIKE RECEPTOR 7; TRANSCRIPTION FACTOR T BET; BCL6 PROTEIN, HUMAN; BCL6 PROTEIN, MOUSE; GAMMA INTERFERON; IFNG PROTEIN, MOUSE; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GERMINAL CENTER; HUMAN; HUMAN CELL; IMMUNE COMPLEX NEPHRITIS; IMMUNOFLUORESCENCE TEST; IMMUNOPATHOGENESIS; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; SPLEEN WEIGHT; SPLENOMEGALY; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE ACTIVATION; UPREGULATION; ANIMAL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; AUTOANTIBODIES; B-LYMPHOCYTES; GERMINAL CENTER; INTERFERON-GAMMA; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-BCL-6; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84969245659     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20151724     Document Type: Article

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