The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection

Journal of Experimental Medicine

Volumn 212, Issue 12, 2015, Pages 2041-2056

  Dominguez, Claudia X ^a   Amezquita, Robert A ^a,b   Guan, Tianxia ^a,b   Marshall, Heather D ^a   Joshi, Nikhil S ^a   Kleinstein, Steven H ^a   Kaech, Susan M ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; CRE RECOMBINASE; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; KRUPPEL LIKE FACTOR 4; L SELECTIN; PROTEIN BCL 2; PROTEIN BCL 6; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR T BET; TRANSCRIPTION FACTORS ZEB2; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; IMMUNOGLOBULIN RECEPTOR; KLRG1 PROTEIN, MOUSE; PROTEIN BINDING; REPRESSOR PROTEIN; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21; TRANSCRIPTOME; ZFHX1B PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARENAVIRUS INFECTION; ARTICLE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL PLASTICITY; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION PROCESS; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; EFFECTOR CELL; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE REPRESSION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA SEQUENCE; ANIMAL; C57BL MOUSE; CLUSTER ANALYSIS; DEFICIENCY; DNA MICROARRAY; FLOW CYTOMETRY; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTIC CHORIOMENINGITIS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; VIROLOGY;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CLUSTER ANALYSIS; FLOW CYTOMETRY; HOMEODOMAIN PROTEINS; HOST-PATHOGEN INTERACTIONS; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-BOX DOMAIN PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; TRANSCRIPTOME;

EID: 84971523245     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20150186     Document Type: Article

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