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Volumn 19, Issue 4, 2013, Pages 494-499

Inadequate T follicular cell help impairs B cell immunity during HIV infection

(17)  Cubas, Rafael A a   Mudd, Joseph C b   Savoye, Anne Laure c   Perreau, Matthieu c   Van Grevenynghe, Julien a   Metcalf, Talibah a   Connick, Elizabeth d   Meditz, Amie d   Freeman, Gordon J e   Abesada Terk, Guillermo f   Jacobson, Jeffrey M g   Brooks, Ari D g   Crotty, Shane h,i   Estes, Jacob D j   Pantaleo, Giuseppe c   Lederman, Michael M b   Haddad, Elias K a  


Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN; INDUCIBLE T CELL COSTIMULATOR; INTERLEUKIN 21; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; IMMUNOGLOBULIN G; INTERLEUKIN DERIVATIVE;

EID: 84878454838     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3109     Document Type: Article
Times cited : (304)

References (40)
  • 1
    • 1542283730 scopus 로고    scopus 로고
    • Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection
    • De Milito, A. et al. Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection. Blood 103, 2180-2186 (2004).
    • (2004) Blood , vol.103 , pp. 2180-2186
    • De Milito, A.1
  • 2
    • 33748176405 scopus 로고    scopus 로고
    • Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection
    • Titanji, K. et al. Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection. Blood 108, 1580-1587 (2006).
    • (2006) Blood , vol.108 , pp. 1580-1587
    • Titanji, K.1
  • 3
    • 34250176946 scopus 로고    scopus 로고
    • Loss of discrete memory B cell subsets is associated with impaired immunization responses in HIV-1 infection and may be a risk factor for invasive pneumococcal disease
    • Hart, M. et al. Loss of discrete memory B cell subsets is associated with impaired immunization responses in HIV-1 infection and may be a risk factor for invasive pneumococcal disease. J. Immunol. 178, 8212-8220 (2007).
    • (2007) J. Immunol , vol.178 , pp. 8212-8220
    • Hart, M.1
  • 4
    • 63149142646 scopus 로고    scopus 로고
    • B cells in HIV infection and disease
    • Moir, S. & Fauci, A.S. B cells in HIV infection and disease. Nat. Rev. Immunol. 9, 235-245 (2009).
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 235-245
    • Moir, S.1    Fauci, A.S.2
  • 5
    • 80053399756 scopus 로고    scopus 로고
    • Loss of memory B cells during chronic HIV infection is driven by Foxo3a-and TRAIL-mediated apoptosis
    • van Grevenynghe, J. et al. Loss of memory B cells during chronic HIV infection is driven by Foxo3a-and TRAIL-mediated apoptosis. J. Clin. Invest. 121, 3877-3888 (2011).
    • (2011) J. Clin. Invest , vol.121 , pp. 3877-3888
    • Van Grevenynghe, J.1
  • 6
    • 0035947417 scopus 로고    scopus 로고
    • Loss of memory (CD27) B lymphocytes in HIV-1 infection
    • De Milito, A., Morch, C., Sonnerborg, A. & Chiodi, F. Loss of memory (CD27) B lymphocytes in HIV-1 infection. AIDS 15, 957-964 (2001).
    • (2001) AIDS , vol.15 , pp. 957-964
    • De Milito, A.1    Morch, C.2    Sonnerborg, A.3    Chiodi, F.4
  • 7
    • 63849131879 scopus 로고    scopus 로고
    • Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
    • Scheid, J.F. et al. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature 458, 636-640 (2009).
    • (2009) Nature , vol.458 , pp. 636-640
    • Scheid, J.F.1
  • 8
    • 80053132436 scopus 로고    scopus 로고
    • Broad neutralization coverage of HIV by multiple highly potent antibodies
    • Walker, L.M. et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature 477, 466-470 (2011).
    • (2011) Nature , vol.477 , pp. 466-470
    • Walker, L.M.1
  • 9
    • 77954920017 scopus 로고    scopus 로고
    • Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
    • Wu, X. et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science 329, 856-861 (2010).
    • (2010) Science , vol.329 , pp. 856-861
    • Wu, X.1
  • 10
    • 79956104027 scopus 로고    scopus 로고
    • Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells
    • Fahey, L.M. et al. Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells. J. Exp. Med. 208, 987-999 (2011).
    • (2011) J. Exp. Med , vol.208 , pp. 987-999
    • Fahey, L.M.1
  • 11
    • 81055157812 scopus 로고    scopus 로고
    • Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection
    • Harker, J.A., Lewis, G.M., Mack, L. & Zuniga, E.I. Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection. Science 334, 825-829 (2011).
    • (2011) Science , vol.334 , pp. 825-829
    • Harker, J.A.1    Lewis, G.M.2    MacK, L.3    Zuniga, E.I.4
  • 12
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty, S. Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 29, 621-663 (2011).
    • (2011) Annu. Rev. Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 13
    • 10544241554 scopus 로고    scopus 로고
    • Quantitative image analysis of HIV-1 infection in lymphoid tissue
    • Haase, A.T. et al. Quantitative image analysis of HIV-1 infection in lymphoid tissue. Science 274, 985-989 (1996).
    • (1996) Science , vol.274 , pp. 985-989
    • Haase, A.T.1
  • 14
    • 43949092756 scopus 로고    scopus 로고
    • Characterization of the follicular dendritic cell reservoir of human immunodeficiency virus type 1
    • Keele, B.F. et al. Characterization of the follicular dendritic cell reservoir of human immunodeficiency virus type 1. J. Virol. 82, 5548-5561 (2008).
    • (2008) J. Virol , vol.82 , pp. 5548-5561
    • Keele, B.F.1
  • 15
    • 84865997747 scopus 로고    scopus 로고
    • Expansion of HIV-specific T follicular helper cells in chronic HIV infection
    • Lindqvist, M. et al. Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J. Clin. Invest. 122, 3271-3280 (2012).
    • (2012) J. Clin. Invest , vol.122 , pp. 3271-3280
    • Lindqvist, M.1
  • 16
    • 84859415408 scopus 로고    scopus 로고
    • Spatial alterations between CD4+ T follicular helper, B, and CD8+ T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape
    • Hong, J.J., Amancha, P.K., Rogers, K., Ansari, A.A. & Villinger, F. Spatial alterations between CD4+ T follicular helper, B, and CD8+ T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape. J. Immunol. 188, 3247-3256 (2012).
    • (2012) J. Immunol , vol.188 , pp. 3247-3256
    • Hong, J.J.1    Amancha, P.K.2    Rogers, K.3    Ansari, A.A.4    Villinger, F.5
  • 17
    • 84865395104 scopus 로고    scopus 로고
    • CD4 T follicular helper cell dynamics during SIV infection
    • Petrovas, C. et al. CD4 T follicular helper cell dynamics during SIV infection. J. Clin. Invest. 122, 3281-3294 (2012).
    • (2012) J. Clin. Invest , vol.122 , pp. 3281-3294
    • Petrovas, C.1
  • 18
    • 26844552845 scopus 로고    scopus 로고
    • Persistence of HIV-1 structural proteins and glycoproteins in lymph nodes of patients under highly active antiretroviral therapy
    • Popovic, M. et al. Persistence of HIV-1 structural proteins and glycoproteins in lymph nodes of patients under highly active antiretroviral therapy. Proc. Natl. Acad. Sci. USA 102, 14807-14812 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 14807-14812
    • Popovic, M.1
  • 19
    • 46049112339 scopus 로고    scopus 로고
    • Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
    • Moir, S. et al. Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J. Exp. Med. 205, 1797-1805 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 1797-1805
    • Moir, S.1
  • 20
    • 49049086136 scopus 로고    scopus 로고
    • CpG oligonucleotides enhance proliferative and effector responses of B cells in HIV-infected individuals
    • Malaspina, A. et al. CpG oligonucleotides enhance proliferative and effector responses of B cells in HIV-infected individuals. J. Immunol. 181, 1199-1206 (2008).
    • (2008) J. Immunol , vol.181 , pp. 1199-1206
    • Malaspina, A.1
  • 21
    • 84870283741 scopus 로고    scopus 로고
    • B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1
    • Karnowski, A. et al. B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. J. Exp. Med. 209, 2049-2064 (2012).
    • (2012) J. Exp. Med , vol.209 , pp. 2049-2064
    • Karnowski, A.1
  • 22
    • 79959328032 scopus 로고    scopus 로고
    • ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
    • Choi, Y.S. et al. ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity 34, 932-946 (2011).
    • (2011) Immunity , vol.34 , pp. 932-946
    • Choi, Y.S.1
  • 23
    • 61449255987 scopus 로고    scopus 로고
    • IL-21: An executor of B cell fate
    • Konforte, D., Simard, N. & Paige, C.J. IL-21: an executor of B cell fate. J. Immunol. 182, 1781-1787 (2009).
    • (2009) J. Immunol , vol.182 , pp. 1781-1787
    • Konforte, D.1    Simard, N.2    Paige, C.J.3
  • 24
    • 84872685720 scopus 로고    scopus 로고
    • The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood
    • Sage, P.T., Francisco, L.M., Carman, C.V. & Sharpe, A.H. The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood. Nat. Immunol. 14, 152-161 (2012).
    • (2012) Nat. Immunol , vol.14 , pp. 152-161
    • Sage, P.T.1    Francisco, L.M.2    Carman, C.V.3    Sharpe, A.H.4
  • 25
    • 79961151137 scopus 로고    scopus 로고
    • Foxp3+ follicular regulatory T cells control the germinal center response
    • Linterman, M.A. et al. Foxp3+ follicular regulatory T cells control the germinal center response. Nat. Med. 17, 975-982 (2011).
    • (2011) Nat. Med , vol.17 , pp. 975-982
    • Linterman, M.A.1
  • 26
    • 79961158055 scopus 로고    scopus 로고
    • Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
    • Chung, Y. et al. Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat. Med. 17, 983-988 (2011).
    • (2011) Nat. Med , vol.17 , pp. 983-988
    • Chung, Y.1
  • 27
    • 80555133319 scopus 로고    scopus 로고
    • Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells
    • Wollenberg, I. et al. Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells. J. Immunol. 187, 4553-4560 (2011).
    • (2011) J. Immunol , vol.187 , pp. 4553-4560
    • Wollenberg, I.1
  • 28
    • 79956198905 scopus 로고    scopus 로고
    • Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells
    • Hams, E. et al. Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells. J. Immunol. 186, 5648-5655 (2011).
    • (2011) J. Immunol , vol.186 , pp. 5648-5655
    • Hams, E.1
  • 29
    • 58449124804 scopus 로고    scopus 로고
    • The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
    • Bauquet, A.T. et al. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat. Immunol. 10, 167-175 (2009).
    • (2009) Nat. Immunol , vol.10 , pp. 167-175
    • Bauquet, A.T.1
  • 30
    • 84859711533 scopus 로고    scopus 로고
    • Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation
    • Kroenke, M.A. et al. Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J. Immunol. 188, 3734-3744 (2012).
    • (2012) J. Immunol , vol.188 , pp. 3734-3744
    • Kroenke, M.A.1
  • 31
    • 0033152267 scopus 로고    scopus 로고
    • The transcription factor c-Maf controls the production of interleukin-4 but not other TH2 cytokines
    • Kim, J.I., Ho, I.C., Grusby, M.J. & Glimcher, L.H. The transcription factor c-Maf controls the production of interleukin-4 but not other TH2 cytokines. Immunity 10, 745-751 (1999).
    • (1999) Immunity , vol.10 , pp. 745-751
    • Kim, J.I.1    Ho, I.C.2    Grusby, M.J.3    Glimcher, L.H.4
  • 32
    • 51849116934 scopus 로고    scopus 로고
    • Decreased levels of circulating IL-21 in HIV-infected AIDS patients: Correlation with CD4+ T-cell counts
    • Iannello, A. et al. Decreased levels of circulating IL-21 in HIV-infected AIDS patients: correlation with CD4+ T-cell counts. Viral Immunol. 21, 385-388 (2008).
    • (2008) Viral Immunol , vol.21 , pp. 385-388
    • Iannello, A.1
  • 33
    • 0037456827 scopus 로고    scopus 로고
    • Antibody neutralization and escape by HIV-1
    • Wei, X. et al. Antibody neutralization and escape by HIV-1. Nature 422, 307-312 (2003).
    • (2003) Nature , vol.422 , pp. 307-312
    • Wei, X.1
  • 34
    • 77953747963 scopus 로고    scopus 로고
    • The PD-1 pathway in tolerance and autoimmunity
    • Francisco, L.M., Sage, P.T. & Sharpe, A.H. The PD-1 pathway in tolerance and autoimmunity. Immunol. Rev. 236, 219-242 (2010).
    • (2010) Immunol. Rev , vol.236 , pp. 219-242
    • Francisco, L.M.1    Sage, P.T.2    Sharpe, A.H.3
  • 35
    • 84855911057 scopus 로고    scopus 로고
    • Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection
    • Butler, N.S. et al. Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection. Nat. Immunol. 13, 188-195 (2012).
    • (2012) Nat. Immunol , vol.13 , pp. 188-195
    • Butler, N.S.1
  • 36
    • 62249172189 scopus 로고    scopus 로고
    • Enhancing SIV-specific immunity in vivo by PD-1 blockade
    • Velu, V. et al. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature 458, 206-210 (2009).
    • (2009) Nature , vol.458 , pp. 206-210
    • Velu, V.1
  • 37
    • 33748439841 scopus 로고    scopus 로고
    • Persistent humoral immune defect in highly active antiretroviral therapy-treated children with HIV-1 infection: Loss of specific antibodies against attenuated vaccine strains and natural viral infection
    • Bekker, V. et al. Persistent humoral immune defect in highly active antiretroviral therapy-treated children with HIV-1 infection: loss of specific antibodies against attenuated vaccine strains and natural viral infection. Pediatrics 118, e315-e322 (2006).
    • (2006) Pediatrics , vol.118
    • Bekker, V.1
  • 38
    • 77953137946 scopus 로고    scopus 로고
    • Impaired generation of hepatitis B virus-specific memory B cells in HIV infected individuals following vaccination
    • Mehta, N. et al. Impaired generation of hepatitis B virus-specific memory B cells in HIV infected individuals following vaccination. Vaccine 28, 3672-3678 (2010).
    • (2010) Vaccine , vol.28 , pp. 3672-3678
    • Mehta, N.1
  • 39
    • 82155178683 scopus 로고    scopus 로고
    • SIV infection of rhesus macaques results in dysfunctional T-and B-cell responses to neo and recall Leishmania major vaccination
    • Klatt, N.R. et al. SIV infection of rhesus macaques results in dysfunctional T-and B-cell responses to neo and recall Leishmania major vaccination. Blood 118, 5803-5812 (2011).
    • (2011) Blood , vol.118 , pp. 5803-5812
    • Klatt, N.R.1
  • 40
    • 0036801658 scopus 로고    scopus 로고
    • Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis
    • Schacker, T.W. et al. Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis. J. Clin. Invest. 110, 1133-1139 (2002).
    • (2002) J. Clin. Invest , vol.110 , pp. 1133-1139
    • Schacker, T.W.1


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