Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

Nature

Volumn 537, Issue 7620, 2016, Pages 417-421

  Im, Se Jin ^a   Hashimoto, Masao ^a   Gerner, Michael Y ^b,c   Lee, Junghwa ^a   Kissick, Haydn T ^a   Burger, Matheus C ^d   Shan, Qiang ^e   Hale, J Scott ^a   Lee, Judong ^a   Nasti, Tahseen H ^a   Sharpe, Arlene H ^f,g   Freeman, Gordon J ^f   Germain, Ronald N ^b   Nakaya, Helder I ^d   Xue, Hai Hui ^e   Ahmed, Rafi ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e UNIVERSITY OF IOWA   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; PROGRAMMED DEATH 1 LIGAND 1; TRANSCRIPTION FACTOR 7; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HNF1A PROTEIN, MOUSE; ICOS PROTEIN, MOUSE; INDUCIBLE T CELL COSTIMULATOR; PDCD1 PROTEIN, MOUSE; PROGRAMMED DEATH 1 RECEPTOR;

APOPTOSIS; CANCER; CELLS AND CELL COMPONENTS; GENE EXPRESSION; OPTIMIZATION; PROTEIN; VIRUS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL RENEWAL; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SELF-RENEWAL; CYTOLOGY; DRUG EFFECTS; HELPER CELL; IMMUNOLOGY; IMMUNOTHERAPY; METABOLISM; PHYSIOLOGY; T LYMPHOCYTE SUBPOPULATION;

LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MUS;

ANIMALS; ANTIGENS, CD28; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SELF RENEWAL; FEMALE; HEMATOPOIETIC STEM CELLS; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; IMMUNOTHERAPY; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; PROGRAMMED CELL DEATH 1 RECEPTOR; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84988266244     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature19330     Document Type: Article

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